Refine
Year of publication
Document Type
- Article (52)
- Book (1)
- Doctoral Thesis (1)
Has Fulltext
- yes (54)
Is part of the Bibliography
- no (54)
Keywords
- LHC (6)
- ALICE (3)
- ALICE experiment (2)
- Bone density (2)
- COVID-19 (2)
- CV9202 (2)
- Magnetic resonance imaging (2)
- Osteoporosis (2)
- Spine (2)
- Tomography (x-ray computed) (2)
- adipose-derived stromal/stem cells (2)
- extracellular vesicles (2)
- hypoxia (2)
- mesenchymal stromal/stem cells (2)
- multidetector computed tomography (2)
- pp collisions (2)
- 900 GeV (1)
- ARDS (1)
- Algorithms (1)
- Artificial Intelligence (1)
- Asian tiger mosquito (1)
- BI1361849 (1)
- Beauty production (1)
- Besitz (1)
- Besitzrecht (1)
- Biodiversity Data (1)
- Biomonitoring (1)
- Bone diseases, Metabolic (1)
- Bone marrow (1)
- Botanical Collections (1)
- Bromeliads (1)
- CD-ROM (1)
- CT dual-energy computed tomography (1)
- Calcium (1)
- Cardiovascular diseases (1)
- Cell Biology (1)
- Clinical trial (1)
- Comparison with QCD (1)
- Complex I (1)
- Complex II (1)
- Computed tomography imaging (1)
- Computed tomography, X-ray (1)
- Congenital (1)
- Conservation (1)
- Contrast agent (1)
- Critical care (1)
- DNA barcoding (1)
- Diagnostic imaging (1)
- Digitization (1)
- Dual-energy computed tomography (1)
- Dysgonomonas (1)
- Edema (1)
- Femtoscopy (1)
- Fetal heart (1)
- Geschichte 1839 (1)
- Glucose (1)
- HBT (1)
- HLA antibodies (1)
- Hadron production (1)
- Heart defects (1)
- Heavy flavor production (1)
- Heavy flavour production (1)
- Heavy-ion collisions (1)
- Herbaria (1)
- Herniated disk (1)
- Hypofractionated radiotherapy (1)
- Image processing (1)
- Immunomonitoring (1)
- Inclusive spectra (1)
- Intensity interferometry (1)
- Intervertebral disc displacement (1)
- Jahrhundert, 19. / Recht (1)
- Landrecht (1)
- Low-copy nuclear gene (1)
- MRI (1)
- Microbiology, Virology & Host Pathogen Interaction (1)
- Microbiota (1)
- Microdialysis (1)
- Mid-rapidity (1)
- Multi-strange baryons (1)
- Myocarditis (1)
- Non-small cell lung cancer (1)
- Nonpenetrating (1)
- Nuclear modification factor (1)
- Osteoporotic fractures (1)
- Outcome (1)
- Oxidative phosphorylation (1)
- PYTHIA (1)
- Pb–Pb (1)
- Phantoms (imaging) (1)
- Plant collections (1)
- Positron emission tomography (1)
- Preussen (1)
- Preußen (1)
- Privateigentum (1)
- Prognostic models (1)
- Proton–proton (1)
- RNA (1)
- RNActive (1)
- Research Infrastructure (1)
- Römisches Recht (1)
- Semantics (1)
- Sibling species (1)
- Single electrons (1)
- Single muons (1)
- Spinal injuries (1)
- Stroke (1)
- Systems & Computational Biology (1)
- TLR2/6 (1)
- Taxonomy (1)
- Tomography (1)
- Transverse momentum (1)
- Truncus arteriosus (1)
- Vaccination (1)
- Vasculitis (1)
- Vertebral body (1)
- Virtual noncalcium reconstructions (1)
- Wolbachia (1)
- Wounds (1)
- X-ray computed (1)
- amino acids (1)
- angiography (1)
- aortic stenosis (1)
- arachidonic acid (1)
- blood flow recovery (1)
- cardiac remodeling (1)
- clear cell sarcoma (1)
- collateral growth (1)
- computer-assisted (1)
- diagnostic imaging (1)
- exosomes (1)
- femoral artery ligation (1)
- heart failure (1)
- heart neoplasms (1)
- immunological risk (1)
- in vivo dosimetry (1)
- innate immunity (1)
- interferon (1)
- kidney transplantation (1)
- liver (1)
- local radiotherapy (1)
- mRNA (1)
- mRNA active cancer immunotherapy (1)
- mRNA vaccine (1)
- magnetic resonance imaging (1)
- microRNA (1)
- neoplasm metastasis (1)
- non-small cell lung cancer (1)
- omega-3 fatty acids (1)
- portal vein (1)
- proteomics (1)
- radiation dosage (1)
- radiation dosimetry (1)
- radiation protection (1)
- rats (1)
- renal tubular epithelial cells (1)
- spectra (1)
- thrombosis (1)
- translatomics (1)
- unacceptable antigen mismatches (1)
- waiting time (1)
- √sN N = 2.76 TeV (1)
Institute
- Medizin (25)
- Physik (20)
- Frankfurt Institute for Advanced Studies (FIAS) (18)
- Informatik (18)
- Senckenbergische Naturforschende Gesellschaft (4)
- Institut für Ökologie, Evolution und Diversität (3)
- Biochemie und Chemie (2)
- Biowissenschaften (2)
- Biochemie, Chemie und Pharmazie (1)
- Psychologie und Sportwissenschaften (1)
Background: Intensive Care Resources are heavily utilized during the COVID-19 pandemic. However, risk stratification and prediction of SARS-CoV-2 patient clinical outcomes upon ICU admission remain inadequate. This study aimed to develop a machine learning model, based on retrospective & prospective clinical data, to stratify patient risk and predict ICU survival and outcomes. Methods: A Germany-wide electronic registry was established to pseudonymously collect admission, therapeutic and discharge information of SARS-CoV-2 ICU patients retrospectively and prospectively. Machine learning approaches were evaluated for the accuracy and interpretability of predictions. The Explainable Boosting Machine approach was selected as the most suitable method. Individual, non-linear shape functions for predictive parameters and parameter interactions are reported. Results: 1039 patients were included in the Explainable Boosting Machine model, 596 patients retrospectively collected, and 443 patients prospectively collected. The model for prediction of general ICU outcome was shown to be more reliable to predict “survival”. Age, inflammatory and thrombotic activity, and severity of ARDS at ICU admission were shown to be predictive of ICU survival. Patients’ age, pulmonary dysfunction and transfer from an external institution were predictors for ECMO therapy. The interaction of patient age with D-dimer levels on admission and creatinine levels with SOFA score without GCS were predictors for renal replacement therapy. Conclusions: Using Explainable Boosting Machine analysis, we confirmed and weighed previously reported and identified novel predictors for outcome in critically ill COVID-19 patients. Using this strategy, predictive modeling of COVID-19 ICU patient outcomes can be performed overcoming the limitations of linear regression models. Trial registration “ClinicalTrials” (clinicaltrials.gov) under NCT04455451.
The first measurement of two-pion Bose–Einstein correlations in central Pb–Pb collisions at √sNN=2.76 TeV at the Large Hadron Collider is presented. We observe a growing trend with energy now not only for the longitudinal and the outward but also for the sideward pion source radius. The pion homogeneity volume and the decoupling time are significantly larger than those measured at RHIC.
Inclusive transverse momentum spectra of primary charged particles in Pb–Pb collisions at √sNN=2.76 TeV have been measured by the ALICE Collaboration at the LHC. The data are presented for central and peripheral collisions, corresponding to 0–5% and 70–80% of the hadronic Pb–Pb cross section. The measured charged particle spectra in |η|<0.8 and 0.3<pT<20 GeV/c are compared to the expectation in pp collisions at the same sNN, scaled by the number of underlying nucleon–nucleon collisions. The comparison is expressed in terms of the nuclear modification factor RAA. The result indicates only weak medium effects (RAA≈0.7) in peripheral collisions. In central collisions, RAA reaches a minimum of about 0.14 at pT=6–7 GeV/c and increases significantly at larger pT. The measured suppression of high-pT particles is stronger than that observed at lower collision energies, indicating that a very dense medium is formed in central Pb–Pb collisions at the LHC.
The inclusive charged particle transverse momentum distribution is measured in proton–proton collisions at s=900 GeV at the LHC using the ALICE detector. The measurement is performed in the central pseudorapidity region (|η|<0.8) over the transverse momentum range 0.15<pT<10 GeV/c. The correlation between transverse momentum and particle multiplicity is also studied. Results are presented for inelastic (INEL) and non-single-diffractive (NSD) events. The average transverse momentum for |η|<0.8 is 〈pT〉INEL=0.483±0.001 (stat.)±0.007 (syst.) GeV/c and 〈pT〉NSD=0.489±0.001 (stat.)±0.007 (syst.) GeV/c, respectively. The data exhibit a slightly larger 〈pT〉 than measurements in wider pseudorapidity intervals. The results are compared to simulations with the Monte Carlo event generators PYTHIA and PHOJET.
Rapidity and transverse momentum dependence of inclusive J/ψ production in pp collisions at √s=7 TeV
(2011)
The ALICE experiment at the LHC has studied inclusive J/ψ production at central and forward rapidities in pp collisions at √s=7 TeV. In this Letter, we report on the first results obtained detecting the J/ψ through the dilepton decay into e+e− and μ+μ− pairs in the rapidity ranges |y|<0.9 and 2.5<y<4, respectively, and with acceptance down to zero pT. In the dielectron channel the analysis was carried out on a data sample corresponding to an integrated luminosity Lint=5.6 nb−1 and the number of signal events is NJ/ψ=352±32(stat.)±28(syst.); the corresponding figures in the dimuon channel are Lint=15.6 nb−1 and NJ/ψ=1924±77(stat.)±144(syst.). The measured production cross sections are σJ/ψ(|y|<0.9)=10.7±1.0(stat.)±1.6(syst.)−2.3+1.6(syst.pol.)μb and σJ/ψ(2.5<y<4)=6.31±0.25(stat.)±0.76(syst.)−1.96+0.95(syst.pol.)μb. The differential cross sections, in transverse momentum and rapidity, of the J/ψ were also measured.
The pT-differential inclusive production cross section of the prompt charm-strange meson Ds+ in the rapidity range |y|<0.5 was measured in proton–proton collisions at s=7 TeV at the LHC using the ALICE detector. The analysis was performed on a data sample of 2.98×108 events collected with a minimum-bias trigger. The corresponding integrated luminosity is Lint=4.8 nb−1. Reconstructing the decay Ds+→ϕπ+, with ϕ→K−K+, and its charge conjugate, about 480 Ds± mesons were counted, after selection cuts, in the transverse momentum range 2<pT<12 GeV/c. The results are compared with predictions from models based on perturbative QCD. The ratios of the cross sections of four D meson species (namely D0, D+, D⁎+ and Ds+) were determined both as a function of pT and integrated over pT after extrapolating to full pT range, together with the strangeness suppression factor in charm fragmentation. The obtained values are found to be compatible within uncertainties with those measured by other experiments in e+e−, ep and pp interactions at various centre-of-mass energies.
he first measurements of the invariant differential cross sections of inclusive π0 and η meson production at mid-rapidity in proton–proton collisions at s=0.9 TeV and s=7 TeV are reported. The π0 measurement covers the ranges 0.4<pT<7 GeV/c and 0.3<pT<25 GeV/c for these two energies, respectively. The production of η mesons was measured at s=√7 TeV in the range 0.4<pT<15 GeV/c. Next-to-Leading Order perturbative QCD calculations, which are consistent with the π0 spectrum at s=0.9 TeV, overestimate those of π0 and η mesons at s=√7 TeV, but agree with the measured η/π0 ratio at s=√7 TeV.
The ALICE Collaboration has measured inclusive J/ψ production in pp collisions at a center-of-mass energy √s=2.76 TeV at the LHC. The results presented in this Letter refer to the rapidity ranges |y|<0.9 and 2.5<y<4 and have been obtained by measuring the electron and muon pair decay channels, respectively. The integrated luminosities for the two channels are Linte=1.1 nb−1 and Lintμ=19.9 nb−1, and the corresponding signal statistics are NJ/ψe+e−=59±14 and NJ/ψμ+μ−=1364±53. We present dσJ/ψ/dy for the two rapidity regions under study and, for the forward-y range, d2σJ/ψ/dydpt in the transverse momentum domain 0<pt<8 GeV/c. The results are compared with previously published results at s=7 TeV and with theoretical calculations.
The ALICE experiment has measured low-mass dimuon production in pp collisions at √s=7 TeV in the dimuon rapidity region 2.5<y<4. The observed dimuon mass spectrum is described as a superposition of resonance decays (η,ρ,ω,η′,ϕ) into muons and semi-leptonic decays of charmed mesons. The measured production cross sections for ω and ϕ are σω(1<pt<5 GeV/c,2.5<y<4)=5.28±0.54(stat)±0.49(syst) mb and σϕ(1<pt<5 GeV/c,2.5<y<4)=0.940±0.084(stat)±0.076(syst) mb. The differential cross sections d2σ/dydpt are extracted as a function of pt for ω and ϕ. The ratio between the ρ and ω cross section is obtained. Results for the ϕ are compared with other measurements at the same energy and with predictions by models.
Identical neutral kaon pair correlations are measured in √s=7 TeV pp collisions in the ALICE experiment. One-dimensional Ks0Ks0 correlation functions in terms of the invariant momentum difference of kaon pairs are formed in two multiplicity and two transverse momentum ranges. The femtoscopic parameters for the radius and correlation strength of the kaon source are extracted. The fit includes quantum statistics and final-state interactions of the a0/f0 resonance. Ks0Ks0 correlations show an increase in radius for increasing multiplicity and a slight decrease in radius for increasing transverse mass, mT, as seen in ππ correlations in pp collisions and in heavy-ion collisions. Transverse mass scaling is observed between the Ks0Ks0 and ππ radii. Also, the first observation is made of the decay of the f2′(1525) meson into the Ks0Ks0 channel in pp collisions.