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The production cross sections of the prompt charmed mesons D0, D+, D∗+ and Ds were measured at mid-rapidity in p-Pb collisions at a centre-of-mass energy per nucleon pair sNN−−−√=5.02 TeV with the ALICE detector at the LHC. D mesons were reconstructed from their decays D0→K−π+, D+→K−π+π+, D∗+→D0π+, D+s→ϕπ+→K−K+π+, and their charge conjugates. The pT-differential production cross sections were measured at mid-rapidity in the interval 1<pT<24 GeV/c for D0, D+ and D∗+ mesons and in 2<pT<12 GeV/c for Ds mesons, using an analysis method based on the selection of decay topologies displaced from the interaction vertex. The production cross sections of the D0, D+ and D∗+ mesons were also measured in three pT intervals as a function of the rapidity ycms in the centre-of-mass system in −1.26<ycms<0.34. In addition, the prompt D0 cross section was measured in pp collisions at s√=7 TeV and p-Pb collisions at sNN−−−√=5.02 TeV down to pT=0 using an analysis technique that is based on the estimation and subtraction of the combinatorial background, without reconstruction of the D0 decay vertex. The nuclear modification factor RpPb(pT), defined as the ratio of the pT-differential D-meson cross section in p-Pb collisions and that in pp collisions scaled by the mass number of the Pb nucleus, was calculated for the four D-meson species and found to be compatible with unity within experimental uncertainties. The results are compared to theoretical calculations that include cold-nuclear-matter effects and to transport model calculations incorporating the interactions of charm quarks with an expanding deconfined medium.
The production cross sections of the prompt charmed mesons D0, D+, D∗+ and Ds were measured at mid-rapidity in p-Pb collisions at a centre-of-mass energy per nucleon pair sNN−−−√=5.02 TeV with the ALICE detector at the LHC. D mesons were reconstructed from their decays D0→K−π+, D+→K−π+π+, D∗+→D0π+, D+s→ϕπ+→K−K+π+, and their charge conjugates. The pT-differential production cross sections were measured at mid-rapidity in the interval 1<pT<24 GeV/c for D0, D+ and D∗+ mesons and in 2<pT<12 GeV/c for Ds mesons, using an analysis method based on the selection of decay topologies displaced from the interaction vertex. The production cross sections of the D0, D+ and D∗+ mesons were also measured in three pT intervals as a function of the rapidity ycms in the centre-of-mass system in −1.26<ycms<0.34. In addition, the prompt D0 cross section was measured in pp collisions at s√=7 TeV and p-Pb collisions at sNN−−−√=5.02 TeV down to pT=0 using an analysis technique that is based on the estimation and subtraction of the combinatorial background, without reconstruction of the D0 decay vertex. The nuclear modification factor RpPb(pT), defined as the ratio of the pT-differential D-meson cross section in p-Pb collisions and that in pp collisions scaled by the mass number of the Pb nucleus, was calculated for the four D-meson species and found to be compatible with unity within experimental uncertainties. The results are compared to theoretical calculations that include cold-nuclear-matter effects and to transport model calculations incorporating the interactions of charm quarks with an expanding deconfined medium.
Particle identification is an important feature of the ALICE detector at the LHC. In particular, for particle identification via the time-of-flight technique, the precise determination of the event collision time represents an important ingredient of the quality of the measurement. In this paper, the different methods used for such a measurement in ALICE by means of the T0 and the TOF detectors are reviewed. Efficiencies, resolution and the improvement of the particle identification separation power of the methods used are presented for the different LHC colliding systems (pp , p-Pb and Pb-Pb) during the first period of data taking of LHC (Run 1).
Particle identification is an important feature of the ALICE detector at the LHC. In particular, for particle identification via the time-of-flight technique, the precise determination of the event collision time represents an important ingredient of the quality of the measurement. In this paper, the different methods used for such a measurement in ALICE by means of the T0 and the TOF detectors are reviewed. Efficiencies, resolution and the improvement of the particle identification separation power of the methods used are presented for the different LHC colliding systems (pp , p-Pb and Pb-Pb) during the first period of data taking of LHC (Run 1).
Particle identification is an important feature of the ALICE detector at the LHC. In particular, for particle identification via the time-of-flight technique, the precise determination of the event collision time represents an important ingredient of the quality of the measurement. In this paper, the different methods used for such a measurement in ALICE by means of the T0 and the TOF detectors are reviewed. Efficiencies, resolution and the improvement of the particle identification separation power of the methods used are presented for the different LHC colliding systems (pp , p-Pb and Pb-Pb) during the first period of data taking of LHC (Run 1).
Das im Jahr 2013 begonnene und für einen Zeitraum von 18 Jahren konzipierte Forschungsvorhaben zielt auf die Erstellung eines historisch-semantischen Wörterbuchs zum Denken der Schule von Salamanca und ihrer Bedeutung für politische Theorie und Recht in der Moderne. Als Grundlage dieses Wörterbuchs wird ein digitales Corpus von zentralen Texten der Schule von Salamanca aufgebaut, das mit der elektronischen Version des Wörterbuchs verknüpft ist und der internationalen und interdisziplinären Forschergemeinschaft direkten Zugriff auf die einschlägigen Quellentexte ermöglicht. Durch die Volltexterschließung der digitalen Quellen wird zugleich ein in seiner Funktionalität neuartiges elektronisches Arbeitsinstrument geschaffen, das einen wichtigen Fortschritt gegenüber allen bisherigen Digitalisierungsprojekten in diesem Bereich darstellt. Dieses Arbeitsinstrument wird auch über seine Funktionalität für das zu erstellende Wörterbuch hinaus qualitativ neue Forschungsmöglichkeiten eröffnen.
Beides – Wörterbuch und Quellencorpus – werden in einem repository erfasst und über eine Webseite als Forschungsinstrument der internationalen scientific community zur Verfügung gestellt. Das Wörterbuch wird zum Schluss der letzten Arbeitsphase zusätzlich in Buchform publiziert. Die weltweite Forschung zur Schule von Salamanca und zu ihrer Wirkungsgeschichte wird damit zum ersten Mal Zugriff auf ein gemeinsames Textcorpus haben und über einen intellektuellen Referenzrahmen für dessen historische Unter-suchung und interdisziplinäre Diskussion verfügen.
Dieser Beitrag soll Ausgangslage und Zielsetzung des Vorhabens zusammenfassen (1.), das geplante Quellencorpus (2.), das Wörterbuch (3.) und den Arbeitsplan (4.) vorstellen.
Objective: Spinal epidural abscess (SEA) is a severe and life-threatening disease. Although commonly performed, the effect of timing in surgical treatment on patient outcome is still unclear. With this study, we aim to provide evidence for early surgical treatment in patients with SEA.
Methods: Patients treated for SEA in the authors' department between 2007 and 2016 were included for analysis and retrospectively analyzed for basic clinical parameters and outcome. Pre- and postoperative neurological status were assessed using the American Spinal Injury Association Impairment Scale (AIS). The self-reported quality of life (QOL) based on the Short-Form Health Survey 36 (SF-36) was assessed prospectively. Surgery was defined as "early", when performed within 12 hours after admission and "late" when performed thereafter. Conservative therapy was preferred and recommend in patients without neurological deficits and in patients denying surgical intervention.
Results: One hundred and twenty-three patients were included in this study. Forty-nine patients (39.8%) underwent early, 47 patients (38.2%) delayed surgery and 27 (21.9%) conservative therapy. No significant differences were observed regarding mean age, sex, diabetes, prior history of spinal infection, and bony destruction. Patients undergoing early surgery revealed a significant better clinical outcome before discharge than patients undergoing late surgery (p=0.001) and conservative therapy. QOL based on SF-36 were significantly better in the early surgery cohort in two of four physical items (physical functioning and bodily pain) and in one of four psychological items (role limitation) after a mean follow-up period of 58 months. Readmission to the hospital and failure of conservative therapy were observed more often in patients undergoing conservative therapy.
Conclusion: Our data on both clinical outcome and QOL provide evidence for early surgery within 12 hours after admission in patients with SEA.
We welcome critical appraisals that help to provide balance; however, Dietrich et al. gave an unjustified reproach. We feel that Dietrich’s position is severely compromised because he serves as an expert for the bisphenol A (BPA) Industry Group (Brussels, Belgium). We would like to respond to the issues raised by Dietrich et al., as well as to their oversights and inappropriate interpretations of our findings...