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Institute
Adams, John ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, Robert V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Carroll, J. ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chaloupka, Petr ; Chattopdhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; de Moura, M. M. ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dong, W. J. ; Dong, Xin ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Mazumdar, M. R. ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Foley, K. J. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, Mikhail L. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kunz, Christopher Lee ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Milosevich, Z. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, Debadeepti ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Mora-Corral, M. J. ; Morozov, Dmitry A. ; Morozov, V. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Norman, B. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, Victor ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, Shashikant C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, Baba V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rai, Gulshan ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schroeder, Lee S. ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Vander Molen, A. M. ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zolnierczuk, Piotr Adam ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
We present STAR measurements of charged hadron production as a function of centrality in Au+Au collisions at sqrt[sNN ]=130 GeV . The measurements cover a phase space region of 0.2< pT <6.0 GeV/c in transverse momentum and -1< eta <1 in pseudorapidity. Inclusive transverse momentum distributions of charged hadrons in the pseudorapidity region 0.5< | eta | <1 are reported and compared to our previously published results for | eta | <0.5 . No significant difference is seen for inclusive pT distributions of charged hadrons in these two pseudorapidity bins. We measured dN/d eta distributions and truncated mean pT in a region of pT > pcutT , and studied the results in the framework of participant and binary scaling. No clear evidence is observed for participant scaling of charged hadron yield in the measured pT region. The relative importance of hard scattering processes is investigated through binary scaling fraction of particle production.
Adams, J. ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Badyal, S. K. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Carroll, J. ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopdhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; de Moura, M. M. ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dogra, Sunil Manohar ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Mazumdar, M. R. ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Foley, K. J. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kunz, Christopher Lee ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Milosevich, Z. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, D. K. ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rai, Gulshan ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schroeder, Lee S. ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Sichtermann, E ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Vander Molen, A. M. ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zolnierczuk, Piotr Adam ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
Results on high transverse momentum charged particle emission with respect to the reaction plane are presented for Au+Au collisions at sqrt[sNN]=200 GeV. Two- and four-particle correlations results are presented as well as a comparison of azimuthal correlations in Au+Au collisions to those in p+p at the same energy. The elliptic anisotropy v2 is found to reach its maximum at pt~3 GeV/c, then decrease slowly and remain significant up to pt ~ 7-10 GeV/c. Stronger suppression is found in the back-to-back high-pt particle correlations for particles emitted out of plane compared to those emitted in plane. The centrality dependence of v2 at intermediate pt is compared to simple models based on jet quenching.
Adams, John ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Carroll, J. ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopdhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; de Moura, M. M. ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Mazumdar, M. R. Dutta ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Foley, K. J. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kunz, Christopher Lee ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William J. ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Milosevich, Z. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, Debadeepti ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Mora-Corral, M. J. ; Morozov, Dmitry A. ; Morozov, V. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Norman, B. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rai, Gulshan ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schroeder, Lee S. ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; de Toledo, A. Szanto ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Molen, A. M. Vander ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, V. P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zolnierczuk, Piotr Adam ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
Transverse energy ( ET ) distributions have been measured for Au+Au collisions at sqrt[sNN ]=200 GeV by the STAR Collaboration at RHIC. ET is constructed from its hadronic and electromagnetic components, which have been measured separately. ET production for the most central collisions is well described by several theoretical models whose common feature is large energy density achieved early in the fireball evolution. The magnitude and centrality dependence of ET per charged particle agrees well with measurements at lower collision energy, indicating that the growth in ET for larger collision energy results from the growth in particle production. The electromagnetic fraction of the total ET is consistent with a final state dominated by mesons and independent of centrality.
Adams, John ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Carroll, J. ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopdhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; Moura, M. M. de ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Mazumdar, M. R. Dutta ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Foley, K. J. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kunz, Christopher Lee ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Milosevich, Z. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, Debadeepti ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Mora-Corral, M. J. ; Morozov, Dmitry A. ; Morozov, V. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Norman, B. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V.K.S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rai, Gulshan ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schroeder, Lee S. ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Molen, A. M. Vander ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, V. P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zolnierczuk, Piotr Adam ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
We present data on e+ e- pair production accompanied by nuclear breakup in ultraperipheral gold-gold collisions at a center of mass energy of 200 GeV per nucleon pair. The nuclear breakup requirement selects events at small impact parameters, where higher-order diagrams for pair production should be enhanced. We compare the data with two calculations: one based on the equivalent photon approximation, and the other using lowest-order quantum electrodynamics (QED). The data distributions agree with both calculations, except that the pair transverse momentum spectrum disagrees with the equivalent photon approach. We set limits on higher-order contributions to the cross section.
Adams, John ; Adler, Clemens ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhatia, V. S. ; Bichsel, Hans ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Cadman, Robert V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Carroll, J. ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chaloupka, Petr ; Chattopdhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; de Moura, M. M. ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Mazumdar, M. R. ; Eckardt, Volker ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Flierl, Dominik Bernhard ; Foley, K. J. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, Ludovic ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Gronstal, S. ; Grosnick, David P. ; Guertin, Steven M. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, Steven Francis ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, Mikhail L. ; Kotchenda, L. ; Kramer, Michael ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kunz, Christopher Lee ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Lansdell, C. L. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; LI, Y. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, Durga Prasad ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, Lilian ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meißner, Falk ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, Michael L. ; Milosevich, Z. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, Debadeepti ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Mora-Corral, M. J. ; Morozov, Dmitry A. ; Morozov, V. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Norman, Benjamin Edward ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, Alexei I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, Vladimir A. ; Phatak, Shashikant C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rai, Gulshan ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, Gael ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, Andrew Allen ; Ruan, Lijuan ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schroeder, Lee S. ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, Stepan S. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; St. Claire, L. ; Stadnik, A. ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Struck, Christof ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Vander Molen, A. M. ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, V. P. ; Vokal, Stanislav ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, John P. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, Z. P. ; Zolnierczuk, Piotr Adam ; Zoulkarneev, Rafael ; Zoulkarneeva, Youlia ; Zubarev, A. N.
The transverse mass spectra and midrapidity yields for Xi s and Omega s are presented. For the 10% most central collisions, the Xi -bar+/h- ratio increases from the Super Proton Synchrotron to the Relativistic Heavy Ion Collider energies while the Xi -/h- stays approximately constant. A hydrodynamically inspired model fit to the Xi spectra, which assumes a thermalized source, seems to indicate that these multistrange particles experience a significant transverse flow effect, but are emitted when the system is hotter and the flow is smaller than values obtained from a combined fit to pi , K, p, and Lambda s.
Adams, J. ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopdhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; de Moura, M. M. ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dogra, Sunil Manohar ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Mazumdar, M. R. ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gaillard, L. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lin, G. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, D. K. ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Mora-Corral, M. J. ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Sarsour, M. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Sichtermann, Ernst P. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Vander Molen, A. M. ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
The pseudorapidity asymmetry and centrality dependence of charged hadron spectra in d+Au collisions at sqrt[sNN ]=200 GeV are presented. The charged particle density at midrapidity, its pseudorapidity asymmetry, and centrality dependence are reasonably reproduced by a multiphase transport model, by HIJING, and by the latest calculations in a saturation model. Ratios of transverse momentum spectra between backward and forward pseudorapidity are above unity for pT below 5 GeV/c . The ratio of central to peripheral spectra in d+Au collisions shows enhancement at 2< pT <6 GeV/c , with a larger effect at backward rapidity than forward rapidity. Our measurements are in qualitative agreement with gluon saturation and in contrast to calculations based on incoherent multiple partonic scatterings.
Adams, J. ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Badyal, S. K. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopadhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; Moura, M. M. de ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dogra, Sunil Manohar ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Mazumdar, M. R. Dutta ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gaillard, L. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lin, G. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, D. K. ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Sarsour, M. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Sichtermann, Ernst P. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Molen, A. M. Vander ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten Jr., C. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
The short-lived K(892)* resonance provides an efficient tool to probe properties of the hot and dense medium produced in relativistic heavy-ion collisions. We report measurements of K* in sqrt[sNN]=200GeV Au+Au and p+p collisions reconstructed via its hadronic decay channels K(892)*0-->K pi and K(892)*±-->K0S pi ± using the STAR detector at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory. The K*0 mass has been studied as a function of pT in minimum bias p+p and central Au+Au collisions. The K*pT spectra for minimum bias p+p interactions and for Au+Au collisions in different centralities are presented. The K*/K yield ratios for all centralities in Au+Au collisions are found to be significantly lower than the ratio in minimum bias p+p collisions, indicating the importance of hadronic interactions between chemical and kinetic freeze-outs. A significant nonzero K*0 elliptic flow (v2) is observed in Au+Au collisions and is compared to the K0S and Lambda v2. The nuclear modification factor of K* at intermediate pT is similar to that of K0S but different from Lambda . This establishes a baryon-meson effect over a mass effect in the particle production at intermediate pT (2<pT <= 4GeV/c).
Adams, John ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Badyal, S. K. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopadhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Sabita ; de Moura, M. M. ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dogra, Sunil Manohar ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Mazumdar, M. R. ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gaillard, L. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Yi ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, Mikhail L. ; Kotchenda, Leonid ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lin, G. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, D. K. ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Sarsour, M. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Sichtermann, E ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Vander Molen, A. M. ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
Midrapidity open charm spectra from direct reconstruction of D0(D0-bar)-->K± pi ± in d+Au collisions and indirect electron-positron measurements via charm semileptonic decays in p+p and d+Au collisions at sqrt[sNN]=200 GeV are reported. The D0(D0-bar) spectrum covers a transverse momentum (pT) range of 0.1<pT<3 GeV/c, whereas the electron spectra cover a range of 1<pT<4 GeV/c. The electron spectra show approximate binary collision scaling between p+p and d+Au collisions. From these two independent analyses, the differential cross section per nucleon-nucleon binary interaction at midrapidity for open charm production from d+Au collisions at BNL RHIC is d sigma NNcc-bar/dy=0.30±0.04(stat)±0.09(syst) mb. The results are compared to theoretical calculations. Implications for charmonium results in A+A collisions are discussed.
Adams, J. ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Badyal, S. K. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopdhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; Moura, M. M. de ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dogra, Sunil Manohar ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Mazumdar, M. R. ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lin, G. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, D. K. ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Sichtermann, Ernst P. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Molen, A. M. Vander ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Jr., C. Whitten ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zolnierczuk, Piotr Adam ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N.
Correlations in the hadron distributions produced in relativistic Au+Au collisions are studied in the discrete wavelet expansion method. The analysis is performed in the space of pseudorapidity (| eta | <= 1) and azimuth(full 2 pi ) in bins of transverse momentum (pt) from 0.14 <= pt <= 2.1GeV/c. In peripheral Au+Au collisions a correlation structure ascribed to minijet fragmentation is observed. It evolves with collision centrality and pt in a way not seen before, which suggests strong dissipation of minijet fragmentation in the longitudinally expanding medium.
Azimuthally sensitive Hanbury Brown-Twiss interferometry in Au+Au collisions at sqrt[sNN]=200 GeV
(2004)
Adams, J. ; Adler, Clemens ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Badyal, S. K. ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bhardwaj, S. ; Bhati, Ashok Kumar ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Cadman, R. V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Carroll, J. ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chaloupka, Petr ; Chattopadhyay, S. ; Chen, H. F. ; Chen, Y. ; Chernenko, S. P. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Majumdar, Mihir Ranjan ; Eckardt, Volker ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faine, V. ; Faivre, Julien ; Fatemi, Renee H. ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fisyak, Yuri V. ; Flierl, Dominik Bernhard ; Foley, K. J. ; Fu, J. ; Gagliardi, Carl A. ; Gagunashvili, N. ; Gans, J. ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Gronstal, S. ; Grosnick, David P. ; Guertin, Steven M. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Heppelmann, Steven Francis ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Horsley, M. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, E. ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Johnson, I. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kovalenko, A. D. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kunde, Gerd J. ; Kunz, Christopher Lee ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, S. ; Lasiuk, Brian ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednický, Richard ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Z. ; Liu, Q. J. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; Lopez-Noriega, M. ; Love, William A. ; Ludlam, Thomas ; Lynn, David ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mangotra, Lalit K. ; Mahapatra, D. P. ; Majka, Richard Daniel ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Milosevich, Z. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, Debadeepti ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Mora-Corral, M. J. ; Morozov, Dmitry A. ; Morozov, V. ; de Moura, M. M. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Norman, B. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Paic, Guy ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rai, Gulshan ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogachevski, O. V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schroeder, Lee S. ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shestermanov, Konstantin E. ; Shimanskii, S. S. ; Singaraju, Rama Narayana ; Simon, F. ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Struck, Christof ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Tonjes, Marguerite Belt ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ullrich, Thomas ; Underwood, David G. ; Van Buren, Gene ; VanderMolen, A. M. ; Varma, Raghava ; Vasilevski, I. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Whitten, Charles A. ; Wieman, Howard ; Willson, Robert ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Yuting, B. ; Zanevski, Y. V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zhaomin, Z. P. ; Zizong, Z. P. ; Żołnierczuk, Piotr Adam ; Zoulkarneev, R. ; Zoulkarneeva, J. ; Zubarev, A. N.
We present the results of a systematic study of the shape of the pion distribution in coordinate space at freeze-out in Au+Au collisions at BNL RHIC using two-pion Hanbury Brown-Twiss (HBT) interferometry. Oscillations of the extracted HBT radii versus emission angle indicate sources elongated perpendicular to the reaction plane. The results indicate that the pressure and expansion time of the collision system are not sufficient to completely quench its initial shape.
System size and centrality dependence of the balance function in A + A collisions at √sNN = 17.2 GeV
(2004)
Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Cerny, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Farantatos, Gerassimos ; Flierl, Dominik Bernhard ; Fodor, Zoltán ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczyński, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence ; Pühlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Richard, Agnes Carol Joanna ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimányi, József
Electric charge correlations were studied for p+p, C+C, Si+Si and centrality selected Pb+Pb collisions at sqrt s_NN = 17.2$ GeV with the NA49 large acceptance detector at the CERN-SPS. In particular, long range pseudo-rapidity correlations of oppositely charged particles were measured using the Balance Function method. The width of the Balance Function decreases with increasing system size and centrality of the reactions. This decrease could be related to an increasing delay of hadronization in central Pb+Pb collisions.
Rybczyński, Maciej ; Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Cerny, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Farantatos, Gerassimos ; Flierl, Dominik Bernhard ; Fodor, Zoltán ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczyński, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence ; Pühlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Richard, Agnes Carol Joanna ; Roland, Christof ; Roland, Gunther ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Susa, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Trainor, Thomas A. ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimányi, József
System size dependence of multiplicity fluctuations of charged particles produced in nuclear collisions at 158 A GeV was studied in the NA49 CERN experiment. Results indicate a non-monotonic dependence of the scaled variance of the multiplicity distribution with a maximum for semi-peripheral Pb+Pb interactions with number of projectile participants of about 35. This effect is not observed in a string-hadronic model of nuclear collision HIJING.
Adams, John ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bradley D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Badyal, S. K. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwaj, Somnath ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bhatia, V. S. ; Bichsel, Hans ; Bielčík, Jaroslav ; Bielčíková, Jana ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, Robert V. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Castillo Castellanos, Javier Ernesto ; Catu, Oana ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopadhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, Jean Pierre ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, Supriya ; Moura, M. M. de ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dogra, Sunil Manohar ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Mazumdar, M. R. Dutta ; Eckardt, Volker ; Edwards, W. R. ; Efimov, Leonid G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Fomenko, K. ; Fu, J. ; Gagliardi, Carl A. ; Gaillard, L. ; Gans, Jonathan Edward ; Ganti, Murthy S. ; Gaudichet, L. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gonzalez, Johan Enmanuel ; Grachov, Oleg A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, Mark Thomas ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, Gerald W. ; Huang, Huan Zhong ; Huang, Shengli ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, William W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kutuev, R. Kh. ; Kuznetsov, A. A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, Jens Sören ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lin, G. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q. J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Langacre, R. S. ; Lopez-Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Yu-Gang ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, Christopher J. ; McShane, Tom S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, D. K. ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Petrov, V. A. ; Phatak, S. C. ; Picha, R. ; Planinic, Mirko ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Sarsour, M. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Sichtermann, Ernst P. ; Simon, F. ; Singaraju, Rama Narayana ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, Aihong ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Leeuwen, Marco van ; Molen, A. M. vander ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Vernet, Renaud ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M. ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, Gary D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir Yurevich ; Zanevsky, Yuri V. ; Zhang, Haibin ; Zhang, W. M. ; Zhang, Z. P. ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N. ; Braem, A. ; Davenport, M. ; De Cataldo, Giacinto ; Di Bari, Domenico ; Martinengo, Paolo ; Nappi, Eugenio ; Paic, Guy ; Posa, E. ; Puiz, F. ; Schyns, Emile
The results from the STAR Collaboration on directed flow (v1), elliptic flow (v2), and the fourth harmonic (v4) in the anisotropic azimuthal distribution of particles from Au+Au collisions at sqrt[sNN]=200GeV are summarized and compared with results from other experiments and theoretical models. Results for identified particles are presented and fit with a blast-wave model. Different anisotropic flow analysis methods are compared and nonflow effects are extracted from the data. For v2, scaling with the number of constituent quarks and parton coalescence are discussed. For v4, scaling with v22 and quark coalescence are discussed.
Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Černý, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Farantatos, Gerassimos ; Flierl, Dominik Bernhard ; Fodor, Zoltan ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin Vasilev ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matey D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczyński, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence ; Pühlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Richard, Agnes Carol Joanna ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimányi, József
Electric charge correlations were studied for p+p, C+C, Si+Si, and centrality selected Pb+Pb collisions at sqrt[sNN]=17.2 GeV with the NA49 large acceptance detector at the CERN SPS. In particular, long-range pseudorapidity correlations of oppositely charged particles were measured using the balance function method. The width of the balance function decreases with increasing system size and centrality of the reactions. This decrease could be related to an increasing delay of hadronization in central Pb+Pb collisions.
Event-by-event fluctuations of particle ratios in central Pb + Pb collisions at 20 to 158 AGeV
(2004)
Roland, Christof ; Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Cerny, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Farantatos, Gerassimos ; Flierl, Dominik Bernhard ; Fodor, Zoltán ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornaś, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin Vasilev ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczyński, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence ; Pühlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Roland, Gunther ; Richard, Agnes Carol Joanna ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Trainor, Thomas A. ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimányi, József
In the vicinity of the QCD phase transition, critical fluctuations have been predicted to lead to non-statistical fluctuations of particle ratios, depending on the nature of the phase transition. Recent results of the NA49 energy scan program show a sharp maximum of the ratio of K+ to Pi+ yields in central Pb+Pb collisions at beam energies of 20-30 AGeV. This observation has been interpreted as an indication of a phase transition at low SPS energies. We present first results on event-by-event fluctuations of the kaon to pion and proton to pion ratios at beam energies close to this maximum.
System-size dependence of strangeness production in nucleus-nucleus collisions at √sNN = 17.3 GeV
(2005)
Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Cerny, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Farantatos, Gerassimos ; Flierl, Dominik Bernhard ; Fodor, Zoltán ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin Vasilev ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczyński, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence ; Pühlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Richard, Agnes Carol Joanna ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Trainor, Thomas A. ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimányi, József
Emission of pi, K, phi and Lambda was measured in near-central C+C and Si+Si collisions at 158 AGeV beam energy. Together with earlier data for p+p, S+S and Pb+Pb, the system-size dependence of relative strangeness production in nucleus-nucleus collisions is obtained. Its fast rise and the saturation observed at about 60 participating nucleons can be understood as onset of the formation of coherent partonic subsystems of increasing size. PACS numbers: 25.75.-q
Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Cerny, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Farantatos, Gerassimos ; Flierl, Dominik Bernhard ; Fodor, Zoltán ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin Vasilev ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczyński, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence ; Pühlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Richard, Agnes Carol Joanna ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Trainor, Thomas A. ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimányi, József
Results are presented on Omega production in central Pb+Pb collisions at 40 and 158 AGeV beam energy. Given are transverse-mass spectra, rapidity distributions, and total yields for the sum Omega+Antiomega at 40 AGeV and for Omega and Antiomega separately at 158 AGeV. The yields are strongly under-predicted by the string-hadronic UrQMD model and are in better agreement with predictions from a hadron gas models. PACS numbers: 25.75.Dw
Flierl, Dominik Bernhard ; Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Černý, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Fodor, Zoltán ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin Vasilev ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczynski, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence ; Pühlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Richard, Agnes Carol Joanna ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Trainor, Thomas A. ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimanyi, József
The hadronic final state of central Pb+Pb collisions at 20, 30, 40, 80, and 158 AGeV has been measured by the CERN NA49 collaboration. The mean transverse mass of pions and kaons at midrapidity stays nearly constant in this energy range, whereas at lower energies, at the AGS, a steep increase with beam energy was measured. Compared to p+p collisions as well as to model calculations, anomalies in the energy dependence of pion and kaon production at lower SPS energies are observed. These findings can be explained, assuming that the energy density reached in central A+A collisions at lower SPS energies is sufficient to transform the hot and dense nuclear matter into a deconfined phase.
Flierl, Dominik Bernhard ; Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Billmeier, Anja ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Brun, René ; Bunčić, Predrag ; Černý, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csato, Péter ; Darmenov, Nikolay ; Dimitrov, Anton ; Dinkelaker, Peter ; Eckardt, Volker ; Farantatos, Gerassimos ; Fodor, Zoltán ; Foka, Panagiota ; Freund, Peter ; Friese, Volker ; Gal, József ; Gaździcki, Marek ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Hohne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kollegger, Thorsten ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin Vasilev ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Mayes, Bill W. ; Melkumov, Georgy L. ; Meurer, Christine ; Mischke, André ; Mitrovski, Michael Kosta ; Molnar, József ; Mrowczynski, Stanislaw ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Pinsky, Lawrence S. ; Puhlhofer, Falk ; Reid, Jeffrey G. ; Renfordt, Rainer Arno Ernst ; Richard, Agnes Carol Joanna ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Sann, Hans ; Schmitz, Norbert ; Seyboth, Peter ; Sikler, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpetery, Imre ; Sziklai, János ; Trainor, Thomas A. ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zaranek, Jacek ; Zimanyi, József
The hadronic final state of central Pb+Pb collisions at 20, 30, 40, 80, and 158 AGeV has been measured by the CERN NA49 collaboration. The mean transverse mass of pions and kaons at midrapidity stays nearly constant in this energy range, whereas at lower energies, at the AGS, a steep increase with beam energy was measured. Compared to p+p collisions as well as to model calculations, anomalies in the energy dependence of pion and kaon production at lower SPS energies are observed. These findings can be explained, assuming that the energy density reached in central A+A collisions at lower SPS energies is sufficient to force the hot and dense nuclear matter into a deconfined phase.
Adams, John ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Amonett, John ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Badyal, S. K. ; Bai, Yu ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Bekele, Selemon ; Belaga, Victoria Vladimirovna ; Bellwied, Rene ; Berger, Jens ; Bezverkhny, B. I. ; Bharadwa, S. ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bhatia, V. S. ; Bichsel, Hans ; Billmeier, Anja ; Bland, Leslie C. ; Blyth, Charles O. ; Bonner, Billy E. ; Botje, Michiel ; Boucham, Abdelkrim ; Brandin, Andrei V. ; Bravar, Alessandro ; Bystersky, M. ; Cadman, R. V. ; Cai, X. Z. ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Castillo Castellanos, Javier Ernesto ; Cebra, Daniel A. ; Chajecki, Zbigniew ; Chaloupka, Petr ; Chattopadhyay, S. ; Chen, H. F. ; Chen, Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Christie, William ; Coffin, J. P. ; Cormier, Thomas Michael ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Das, S. ; Moura, M. M. de ; Derevschikov, Anatoly A. ; Didenko, Lidia ; Dietel, Thomas ; Dogra, Sunil Manohar ; Dong, W. J. ; Dong, X. ; Draper, James E. ; Du, F. ; Dubey, Anand Kumar ; Dunin, V. B. ; Dunlop, James C. ; Dutta Mazumdar, M. R. ; Eckardt, Volker ; Edwards, W. R. ; Efimov, L. G. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Fachini, Patricia ; Faivre, Julien ; Fatemi, Renee H. ; Fedorišin, Jan ; Filimonov, Kirill ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Fomenko, K. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Guertin, Steven M. ; Guo, Y. ; Gupta, Anik ; Gutierrez, Thomas Dominic ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Hardtke, David H. ; Harris, John W. ; Heinz, M. ; Henry, Thomas W. ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffmann, G. W. ; Huang, H. Z. ; Huang, S. L. ; Hughes, Emlyn Willard ; Humanic, Thomas J. ; Igo, George J. ; Ishihara, A. ; Jacobs, Peter Martin ; Jacobs, W.W. ; Janik, Michał ; Jiang, H. ; Jones, Peter Graham ; Judd, Eleanor G. ; Kabana, Sonia ; Kang, K. ; Kaplan, Morton ; Keane, Declan ; Khodyrev, V. Yu. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Kislov, E. M. ; Klay, Jennifer Lynn ; Klein, Spencer Robert ; Klyachko, A. ; Koetke, Donald D. ; Kollegger, Thorsten ; Kopytine, M. ; Kotchenda, L. ; Kramer, M. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Kuhn, Christian Claude ; Kulikov, Anatoly I. ; Kumar, Ajay ; Kutuev, R.Kh. ; Kuznetsov, A.A. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; Lange, Jens Sören ; Laue, Frank ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lehocka, S. ; LeVine, Micheal J. ; Li, C. ; Li, Q. ; Li, Y. ; Lin, G. ; Lindenbaum, S. J. ; Lisa, Michael A. ; Liu, F. ; Liu, L. ; Liu, Q.J. ; Liu, Z. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Long, H. ; Longacre, Ronald S. ; López Noriega, M. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G. L. ; Ma, Jing-guo ; Ma, Y. G. ; Magestro, Daniel ; Mahajan, Sanjay ; Mahapatra, D. P. ; Majka, Richard Daniel ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Martin, L. ; Marx, Jay N. ; Matis, Howard S. ; Matulenko, Yuri A. ; McClain, C. J. ; McShane, T. S. ; Meissner, F. ; Melnick, Yu. ; Meščanin, Aleksei P. ; Miller, M. L. ; Minaev, Nikolai G. ; Mironov, Camelia ; Mischke, André ; Mishra, D. K. ; Mitchell, J. ; Mohanty, Bedangadas ; Molnar, Levente ; Moore, C. F. ; Morozov, D. A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nayak, S. K. ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Nikitin, Vladimir A. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okorokov, Vitaly A. ; Oldenburg, Markus D. ; Olson, Douglas L. ; Pal, Susanta Kumar ; Panebratsev, Yuri ; Panitkin, Sergei Yurievich ; Pavlinov, A. I. ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Pluta, Jan Marian ; Porile, Norbert T. ; Porter, Jeffrey Brent ; Poskanzer, Arthur M. ; Potekhin, Maxim ; Potrebenikova, E. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Putschke, Jörn H. ; Rakness, Gregory L. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ravel, Olivier ; Ray, Robert L. ; Razin, Sergej V. ; Reichhold, Dennis Michael ; Reid, Jeffrey G. ; Renault, G. ; Retiere, Fabrice ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, Lijuan ; Sahoo, Raghunath ; Sakrejda, Iwona ; Salur, Sevil ; Sandweiss, Jack H. ; Savin, Igor A. ; Sazhin, P. S. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Schweda, Kai ; Seger, Janet Elizabeth ; Seyboth, Peter ; Shahaliev, Ehtiram ; Shao, M. ; Shao, W. ; Sharma, M. ; Shen, W. Q. ; Shestermanov, Konstantin E. ; Shimanskiy, S. S. ; Sichtermann, E ; Simon, F. ; Singaraju, R. N. ; Skoro, Goran P. ; Smirnov, Nikolai ; Snellings, Raimond ; Sood, Gopika ; Sorensen, Paul Richard ; Sowinski, James ; Speltz, Jeff ; Spinka, Harold. M. ; Srivastava, Brijesh Kumar ; Stadnik, A. ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Stock, Reinhard ; Stock, Reinhard ; Stolpovsky, Alexander ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Sugarbaker, Evan R. ; Suire, Christophe Pierre ; Šumbera, Michal ; Surrow, Bernd ; Symons, T. J. M. ; Toledo, Alejandro Szanto de ; Szarwas, Piotr ; Tai, An ; Takahashi, Jun ; Tang, A. H. ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Timoshenko, Sergei ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Urkinbaev, Anarbay ; Van Buren, Gene ; Ward, H. ; Watson, J. W. ; Webb, Jason C. ; Wells, R. ; Westfall, G. D. ; Wetzler, Alexander Albert ; Whitten, Charles A. ; Wieman, H. ; Wissink, Scott W. ; Witt, Richard ; Wood, J. ; Wu, J. ; Xu, N. ; Xu, Z. ; Xu, Z. Z. ; Yamamoto, E. ; Yepes, Pablo P. ; Yurevich, Vladimir I. ; Zanevsky, Yuri V. ; Zhang, Haitao ; Zhang, W. M. ; Zhang, Z. P. ; Zolnierczuk, Piotr Adam ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zubarev, A. N. ; Leeuwen, Marco van ; Vander Molen, A. M. ; Varma, Raghava ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Verne, R. ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, S. A. ; Vznuzdaev, Marat ; Waggoner, William T. ; Wang, F. ; Wang, G. ; Wang, X. L. ; Wang, Y. ; Wang, Y. ; Wang, Z. M.
We present a systematic analysis of two-pion interferometry in Au+Au collisions at sqrt[sNN]=200GeV using the STAR detector at Relativistic Heavy Ion Collider. We extract the Hanbury-Brown and Twiss radii and study their multiplicity, transverse momentum, and azimuthal angle dependence. The Gaussianness of the correlation function is studied. Estimates of the geometrical and dynamical structure of the freeze-out source are extracted by fits with blast-wave parametrizations. The expansion of the source and its relation with the initial energy density distribution is studied.
Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, Juraj ; Bramm, Roland ; Bunčić, Predrag ; Cerny, Vladimír ; Christakoglou, Panagiotis ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Dinkelaker, Peter ; Eckardt, Volker ; Flierl, Dominik Bernhard ; Fodor, Zoltán ; Foka, Panagiota ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Genchev, Vladimir ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, Alexandre ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kornas, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin ; Malakhov, Aleksandr I. ; Markert, Christina ; Mateev, Matej D. ; Melkumov, Georgy L. ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczyński, Stanislaw ; Nicolic, V. ; Pálla, Gabriella ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Pikna, Miroslav ; Prindle, Duncan J. ; Pühlhofer, Falk ; Renfordt, Rainer Arno Ernst ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Schmitz, Norbert ; Schuster, Tim ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Stefanek, Grzegorz ; Stock, Reinhard ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Szymański, Paweł ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Yoo, In-Kwon ; Zimányi, József
Results are presented from a search for the decays D0 -> K min pi plus and D0 bar -> K plus pi min in a sample of 3.8x10^6 central Pb-Pb events collected with a beam energy of 158A GeV by NA49 at the CERN SPS. No signal is observed. An upper limit on D0 production is derived and compared to predictions from several models.
Alt, Christopher ; Antičić, Tome ; Baatar, B. ; Barna, Daniel ; Bartke, Jerzy ; Betev, Latchezar ; Białkowska, Helena ; Blume, Christoph ; Boimska, Bożena ; Botje, Michiel ; Bracinik, J. ; Bramm, Roland ; Černý, Vladimír ; Christakoglou, Panagiotis ; Chung, P. ; Chvala, Ondrej ; Cramer, John G. ; Csató, Péter ; Dinkelaker, Peter ; Eckard, V. ; Flierl, Dominik Bernhard ; Fodor, Zoltán ; Foka, Panagiota ; Friese, Volker ; Gál, József ; Gaździcki, Marek ; Genchev, Vladimir ; Georgopoulos, George ; Gładysz-Dziaduś, Ewa ; Grebieszkow, Katarzyna ; Hegyi, Sándor ; Höhne, Claudia ; Kadija, Krešo ; Karev, A. ; Kikola, D. ; Kliemant, Michael ; Kniege, Stefan ; Kolesnikov, Vadim I. ; Kornaś, Ewelina ; Korus, Robert ; Kowalski, Marek ; Kraus, Ingrid ; Kreps, Michal ; Laszlo, A. ; Lacey, R ; Leeuwen, Marco van ; Lévai, Péter ; Litov, Leandr ; Lungwitz, Benjamin ; Makariev, Martin ; Malakhov, Aleksandr I. ; Mateev, Matej D. ; Melkumov, Georgy L. ; Mischke, André ; Mitrovski, Michael Kosta ; Molnár, József ; Mrówczynski, Stanislaw ; Nicolic, V. ; Nicolic, G. ; Panagiotou, Apostolos D. ; Panayotov, Dobromir ; Petridis, Athanasios ; Peryt, Wiktor Stanislaw ; Pikna, Miroslav ; Pluta, Jan Marian ; Prindle, Duncan J. ; Pühlhofer, Falk ; Renfordt, Rainer Arno Ernst ; Roland, Christof ; Roland, Gunther ; Rybczyński, Maciej ; Rybicki, Andrzej ; Sandoval, Andres ; Schmitz, N. ; Schuster, Tim ; Seyboth, Peter ; Siklér, Ferenc ; Sitar, Branislav ; Skrzypczak, Ewa ; Slodkowski, M. ; Stefanek, Grzegorz ; Stock, Reinhard ; Strabel, Claudia ; Ströbele, Herbert ; Šuša, Tatjana ; Szentpétery, Imre ; Sziklai, János ; Szuba, M. ; Szymanski, P. ; Trubnikov, Victor ; Varga, Dezsö ; Vassiliou, Maria ; Veres, Gábor I. ; Vesztergombi, György ; Vranić, Danilo ; Wetzler, Alexander Albert ; Włodarczyk, Zbigniew ; Wojtaszek, A. ; Yoo, In-Kwon ; Zimányi, József
The energy dependence of multiplicity fluctuations was studied for the most central Pb+Pb collisions at 20A, 30A, 40A, 80A and 158A GeV by the NA49 experiment at the CERN SPS. The multiplicity distribution for negatively and positively charged hadrons is significantly narrower than Poisson one for all energies. No significant structure in energy dependence of the scaled variance of multiplicity fluctuations is observed. The measured scaled variance is lower than the one predicted by the grand-canonical formulation of the hadron-resonance gas model. The results for scaled variance are in approximate agreement with the string-hadronic model UrQMD.
Dongen, Jenny van ; Hagenbeek, Fiona A. ; Suderman, Matthew ; Roetman, Peter J. ; Sugden, Karen ; Geburtig-Chiocchetti, Andreas ; Ismail, Khadeeja ; Mulder, Rosa H. ; Hafferty, Jonathan D. ; Adams, Mark J. ; Walker, Rosie M. ; Morris, Stewart W. ; Lahti, Jari ; Küpers, Leanne K. ; Escaramis, Georgia ; Alemany, Silvia ; Bonder, Marc Jan ; Meijer, Mandy ; Ip, Hill F. ; Jansen, Rick ; Baselmans, Bart M. L. ; Parmar, Priyanka ; Lowry, Estelle ; Streit, Fabian ; Sirignano, Lea ; Send, Tabea S. ; Frank, Josef ; Jylhävä, Juulia ; Wang, Yunzhang ; Mishra, Pashupati Prasad ; Colins, Olivier F. ; Corcoran, David L. ; Poulton, Richie ; Mill, Jonathan ; Hannon, Eilis ; Arseneault, Louise ; Korhonen, Tellervo ; Vuoksimaa, Eero ; Felix, Janine F. ; Bakermans-Kranenburg, Marian J. ; Campbell, Archie ; Czamara, Darina ; Binder, Elisabeth ; Corpeleijn, Eva ; González Ruiz, Juan Ramon ; Grazuleviciene, Regina ; Gutzkow, Kristine B. ; Evandt, Jorunn ; Vafeiadi, Marina ; Klein, Marieke ; Meer, Dennis van der ; Ligthart, Lannie ; Heijmans, Bastiaan Theodoor ; Hoen, Peter A. C. 't ; Meurs, Joyce Berdina Josepha van ; Franke, Lude ; Boomsma, Dorret I. ; Pool, René ; Hottenga, Jouke J. ; Greevenbroek, Marleen M. J. van ; Stehouwer, Coen D. A. ; Kallen, Carla J. H. van der ; Schalkwijk, Casper G. ; Wijmenga, Cisca ; Zhernakova, Sasha ; Tigchelaar, Ettje F. ; Slagboom, P. Eline ; Beekman, Marian ; Deelen, Joris ; Heemst, Diana van ; Veldink, Jan H. ; Berg, Leonard H. van den ; Duijn, Cornelia M. van ; Hofman, Bert A. ; Isaacs, Aaron ; Uitterlinden, André G. ; Jhamai, P. Mila ; Verbiest, Michael ; Suchiman, H. Eka D. ; Verkerk, Marijn ; Breggen, Ruud van der ; Rooij, Jeroen van ; Lakenberg, Nico ; Mei, Hailiang ; Iterson, Maarten van ; Galen, Michiel van ; Bot, Jan ; Zhernakova, Dasha V. ; Hof, Peter van ’t ; Deelen, Patrick ; Nooren, Irene ; Moed, Matthijs ; Vermaat, Martijn ; Luijk, René ; Dijk, Freerk van ; Arindrarto, Wibowo ; Kielbasa, Szymon M. ; Swertz, Morris A. ; Zwet, Erik. W. van ; Hoen, Peter-Bram ’t ; Kluft, Cornelis ; Davies, Gareth E. ; Hakulinen, Christian ; Keltikangas-Järvinen, Liisa ; Franke, Barbara ; Freitag, Christine M. ; Konrad, Kerstin ; Hervás, Amaia ; Fernández-Rivas, Aranzazu ; Vetro, Agnes ; Raitakari, Olli ; Lehtimäki, Terho ; Vermeiren, Robert ; Strandberg, Timo ; Räikkönen, Katri ; Snieder, Harold ; Witt, Stephanie H. ; Deuschle, Michael ; Pedersen, Nancy L. ; Hägg, Sara ; Sunyer, Jordi ; Kaprio, Jaakko ; Ollikainen, Miina ; Moffitt, Terrie E. ; Tiemeier, Henning ; IJzendoorn, Marinus H. van ; Relton, Caroline ; Vrijheid, Martine ; Sebert, Sylvain ; Jarvelin, Marjo-Riitta ; Caspi, Avshalom ; Evans, Kathryn L. ; McIntosh, Andrew M. ; Bartels, Meike
DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of genetic, stochastic, and environmental influences associated with aggression. Here, we report the first large meta-analysis of epigenome-wide association studies (EWAS) of aggressive behavior (N = 15,324 participants). In peripheral blood samples of 14,434 participants from 18 cohorts with mean ages ranging from 7 to 68 years, 13 methylation sites were significantly associated with aggression (alpha = 1.2 × 10−7; Bonferroni correction). In cord blood samples of 2425 children from five cohorts with aggression assessed at mean ages ranging from 4 to 7 years, 83% of these sites showed the same direction of association with childhood aggression (r = 0.74, p = 0.006) but no epigenome-wide significant sites were found. Top-sites (48 at a false discovery rate of 5% in the peripheral blood meta-analysis or in a combined meta-analysis of peripheral blood and cord blood) have been associated with chemical exposures, smoking, cognition, metabolic traits, and genetic variation (mQTLs). Three genes whose expression levels were associated with top-sites were previously linked to schizophrenia and general risk tolerance. At six CpGs, DNA methylation variation in blood mirrors variation in the brain. On average 44% (range = 3–82%) of the aggression–methylation association was explained by current and former smoking and BMI. These findings point at loci that are sensitive to chemical exposures with potential implications for neuronal functions. We hope these results to be a starting point for studies leading to applications as peripheral biomarkers and to reveal causal relationships with aggression and related traits.
Abelev, Betty ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Bai, Y. ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Baumgart, S. ; Beavis, D.R. ; Bellwied, Rene ; Benedosso, F. ; Betancourt, M.J. ; Betts, R.R. ; Bharadwaj, Somnath ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bichsel, Hans ; Bielčík, Jaroslav ; Bielčíková, Jana ; Biritz, B. ; Bland, Leslie C. ; Bombara, Marek ; Bonner, B.E. ; Botje, Michiel ; Bouchet, J. ; Braidot, E. ; Brandin, Andrei V. ; Bruna, Elena ; Bueltmann, S. ; Burton, T.P. ; Bystersky, M. ; Cai, X.Z. ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Callner, J. ; Catu, O. ; Cebra, Daniel A. ; Cendejas, R. ; Cervantes, M.C. ; Chajecki, Z. ; Chaloupka, Petr ; Chattopadhyay, S. ; Chen, H.F. ; Chen, J.H. ; Chen, J.Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Choi, K.E. ; Christie, William ; Chung, Suh-Urk ; Clarke, R.F. ; Codrington, M.J. ; Coffin, Jean Pierre ; Corliss, R. ; Cormier, Thomas Michael ; Cosentino, Mauro Rogerio ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Dash, Sadhana ; Daugherity, M. ; De Silva, C. ; Dedovič, Tatiana G. ; DePhillips, M. ; Derevschikov, Anatoly A. ; Souza, Rafael Derradi de ; Didenko, Lidia ; Djawotho, P. ; Dogra, Sunil Manohar ; Dong, X. ; Drachenberg, James Lucus ; Draper, James E. ; Du, F. ; Dunlop, James C. ; Dutta Mazumdar, M.R. ; Edwards, W.R. ; Efimov, Leonid G. ; Elhalhuli, E. ; Elnimr, M. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Eun, L. ; Fachini, Patricia ; Fatemi, Renee H. ; Fedorišin, Jan ; Feng, A. ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Gagliardi, Carl A. ; Gaillard, L. ; Gangadharan, Dhevan Raja ; Ganti, Murthy S. ; Garcia-Solis, Edmundo Javier ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gorbunov, Y.N. ; Gordon, A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Grube, B. ; Guertin, Steven M. ; Guimaraes, K.S.F.F. ; Gupta, Anik ; Gupta, N. ; Guryn, Włodzimierz ; Haag, B. ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Harris, John W. ; He, W. ; Heinz, Mark Thomas ; Hepplemann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffman, A.M. ; Hoffmann, Gerald W. ; Hofman, D.J. ; Hollis, R.S. ; Huang, Huan Zhong ; Humanic, Thomas J. ; Igo, George J. ; Iordanova, A. ; Jacobs, P. ; Jacobs, William W. ; Jakl, P. ; Jin, F. ; Jones, C.L. ; Jones, Peter Graham ; Joseph, J. ; Judd, Eleanor G. ; Kabana, Sonia ; Kajimoto, K. ; Kang, K. ; Kapitan, J. ; Kaplan, Morton ; Keane, Declan ; Kechechyan, Armen ; Kettler, D. ; Khodyrev, V.Yu. ; Kikola, D.P. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Klein, Spencer Robert ; Knospe, Anders Garritt ; Kocoloski, A. ; Koetke, Donald D. ; Kopytine, M. ; Kotchenda, L. ; Kouchpil, V. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Krus, M. ; Kuhn, Christian Claude ; Kumar, Lokesh ; Kurnadi, P. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; LaPointe, S. ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lee, C.-H. ; Leight, W. ; LeVine, Micheal J. ; Li, C. ; Li, Y. ; Lin, G. ; Lin, X. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, H. ; Liu, J. ; Liu, L. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Longacre, Ronald S. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Lynn, David ; Ma, G.L. ; Ma, Yu-Gang ; Mahapatra, Durga Prasad ; Majka, Richard Daniel ; Mall, O.I. ; Mangotra, L.K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Matis, Howard S. ; Matulenko, Yu.A. ; McShane, Tom S. ; Meščanin, Aleksei P. ; Millner, R. ; Minaev, Nikolai G. ; Mioduszewski, Saskia ; Mischke, André ; Mitchell, J. ; Mohanty, Bedangadas ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nattrass, Christine ; Nayak, Tapan Kumar ; Nelson, John M. ; Nepali, C. ; Netrakanti, Pawan Kumar ; Ng, M.J. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okada, H. ; Okorokov, Vitaly A. ; Olson, Douglas L. ; Pachr, Miloš ; Page, Brian S. ; Pal, Susanta Kumar ; Pandit, Y. ; Panebratsev, Yuri ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Phatak, S.C. ; Planinic, Mirko ; Pluta, Jan Marian ; Poljak, Nikola ; Poskanzer, Arthur M. ; Potukuchi, B.V.K.S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Pruthi, Navneet Kumar ; Putschke, Jörn H. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ray, Robert L. ; Redwine, R. ; Reed, Rosi Jan ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, L. ; Russcher, M.J. ; Rykov, Vladimir L. ; Sahoo, Raghunath ; Sakrejda, Iwona ; Sakuma, T. ; Salur, Sevil ; Sandweiss, Jack H. ; Sarsour, M. ; Savin, Igor A. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Seger, Janet Elizabeth ; Selyuzhenkov, Ilya ; Seyboth, Peter ; Shabetai, Alexandre ; Shahaliev, Ehtiram ; Shao, M. ; Sharma, M. ; Shi, Shusu ; Shi, X.-H. ; Sichtermann, Ernst P. ; Simon, F. ; Singaraju, Rama Narayana ; Skoby, Michael J. ; Smirnov, Nikolai ; Snellings, Raimond ; Sorensen, Paul Richard ; Sowinski, James ; Spinka, Harold. M. ; Srivastava, B. ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Staszak, D. ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Suarez, M.C. ; Subba, N.L. ; Šumbera, Michal ; Sun, X.M. ; Sun, Y. ; Sun, Z. ; Surrow, Bernd ; Symons, Timothy James MacNeil ; Toledo, Alejandro Szanto de ; Takahashi, Jun ; Tang, Aihong ; Tang, Zebo ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Tian, J. ; Timmins, Anthony Robert ; Timoshenko, Sergei ; Tlusty, David ; Tokarev, Mikhail V. ; Trainor, T.A. ; Tram, V.N. ; Trattner, A.L. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Van Buren, Gene ; Leeuwen, Marco van ; Vander Molen, A.M. ; Vanfossen, J.A. ; Varma, Raghava ; Vasconcelos, G.M.S. ; Vasilevski, I.M. ; Vasiliev, Alexander Nikolaevich ; Videbæk, Flemming ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Wada, M. ; Waggoner, William T. ; Walker, M. ; Wang, F. ; Wang, G. ; Wang, J.S. ; Wang, Q. ; Wang, X. ; Wang, X.L. ; Wang, Y. ; Webb, Jason C. ; Westfall, Gary D. ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wu, Y. ; Xu, N. ; Xu, Qinghua ; Xu, Y. ; Xu, Z. ; Yepes, Pablo P. ; Yoo, In-Kwon ; Yue, Q. ; Zawisza, M. ; Zbroszczyk, Hanna Paulina ; Zhan, W. ; Zhang, H. ; Zhang, S. ; Zhang, W.M. ; Zhang, Y. ; Zhang, Z.P. ; Zhao, Y. ; Zhong, C. ; Zhou, J. ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zuo, J.X.
We study the beam-energy and system-size dependence of \phi meson production (using the hadronic decay mode \phi -- K+K-) by comparing the new results from Cu+Cu collisions and previously reported Au+Au collisions at \sqrt{s_NN} = 62.4 and 200 GeV measured in the STAR experiment at RHIC. Data presented are from mid-rapidity (|y|<0.5) for 0.4 < pT < 5 GeV/c. At a given beam energy, the transverse momentum distributions for \phi mesons are observed to be similar in yield and shape for Cu+Cu and Au+Au colliding systems with similar average numbers of participating nucleons. The \phi meson yields in nucleus-nucleus collisions, normalised by the average number of participating nucleons, are found to be enhanced relative to those from p+p collisions with a different trend compared to strange baryons. The enhancement for \phi mesons is observed to be higher at \sqrt{s_NN} = 200 GeV compared to 62.4 GeV. These observations for the produced \phi(s\bar{s}) mesons clearly suggest that, at these collision energies, the source of enhancement of strange hadrons is related to the formation of a dense partonic medium in high energy nucleus-nucleus collisions and cannot be alone due to canonical suppression of their production in smaller systems.
Abelev, Betty ; Aggarwal, Madan Mohan ; Ahammed, Zubayer ; Anderson, Bryon D. ; Arkhipkin, Dmitry A. ; Averichev, Georgy S. ; Balewski, Jan ; Barannikova, Olga ; Barnby, Lee Stuart ; Baudot, Jérome ; Baumgart, S. ; Beavis, D. R. ; Bellwied, Rene ; Benedosso, F. ; Betancourt, M. J. ; Betts, R. R. ; Bhasin, Anju ; Bhati, Ashok Kumar ; Bichsel, Hans ; Bielčík, Jaroslav ; Bielčíková, Jana ; Biritz, B. ; Bland, Leslie C. ; Bombara, Marek ; Bonner, Billy E. ; Botje, Michiel ; Bouchet, J. ; Braidot, E. ; Brandin, Andrei V. ; Bruna, Elena ; Bueltmann, S. ; Burton, T. P. ; Bystersky, M. ; Cai, Xiang-Zhou ; Caines, Helen Louise ; Calderón de la Barca Sánchez, Manuel ; Catu, O. ; Cebra, Daniel A. ; Cendejas, R. ; Cervantes, M. C. ; Chajecki, Z. ; Chaloupka, Petr ; Chattopadhyay, S. ; Chen, H. F. ; Chen, J. H. ; Chen, J. Y. ; Cheng, J. ; Cherney, Michael Gerard ; Chikanian, Alexei ; Choi, K. E. ; Christie, William ; Clarke, R. F. ; Codrington, M. J. M. ; Corliss, R. ; Cormier, Thomas Michael ; Cosentino, Mauro Rogerio ; Cramer, John G. ; Crawford, Henry J. ; Das, Debasish ; Dash, Sadhana ; Daugherity, M. ; Silva, L. C. De ; Dedovich, T. G. ; DePhillips, M. ; Derevschikov, Anatoly A. ; de Souza, R. Derradi ; Didenko, Lidia ; Djawotho, P. ; Dogra, Sunil Manohar ; Dong, X. ; Drachenberg, James Lucus ; Draper, James E. ; Dunlop, James C. ; Mazumdar, M. R. Dutta ; Edwards, W. R. ; Efimov, Leonid G. ; Elhalhuli, E. ; Elnimr, M. ; Emelianov, V. ; Engelage, Jon M. ; Eppley, Geary Wareham ; Erazmus, Barbara Ewa ; Estienne, Magali Danielle ; Eun, L. ; Fachini, Patricia ; Fatemi, Renee H. ; Fedorišin, Jan ; Feng, A. ; Filip, Peter ; Finch, Evan ; Fine, Valeri ; Fisyak, Yuri V. ; Gagliardi, Carl A. ; Gaillard, L. ; Gangadharan, Dhevan Raja ; Ganti, Murthy S. ; Garcia-Solis, E. J. ; Geromitsos, A. ; Geurts, Frank ; Ghazikhanian, Vahe ; Ghosh, Premomoy ; Gorbunov, Y. N. ; Gordon, A. ; Grebenyuk, Oleksandr ; Grosnick, David P. ; Grube, B. ; Guertin, Steven M. ; Guimaraes, K. S. F. F. ; Gupta, Anik ; Gupta, N. ; Guryn, Włodzimierz ; Haag, B. ; Hallman, Timothy J. ; Hamed, Ahmed M. ; Harris, John W. ; He, W. ; Heinz, Mark Thomas ; Heppelmann, S. ; Hippolyte, Boris ; Hirsch, Andrew S. ; Hjort, Eric ; Hoffman, A. M. ; Hoffmann, Gerald W. ; Hofman, D. J. ; Hollis, R. S. ; Huang, Huan Zhong ; Humanic, Thomas J. ; Huo, L. ; Igo, George J. ; Iordanova, A. ; Jacobs, P. ; Jacobs, William W. ; Jakl, P. ; Jena, Chitrasen ; Jin, F. ; Jones, C. L. ; Jones, Peter Graham ; Joseph, J. ; Judd, Eleanor G. ; Kabana, Sonia ; Kajimoto, K. ; Kang, K. ; Kapitan, J. ; Keane, Declan ; Kechechyan, Armen ; Kettler, D. ; Khodyrev, V. Yu. ; Kikola, D. P. ; Kiryluk, Joanna ; Kisiel, Adam Ryszard ; Klein, Spencer Robert ; Knospe, Anders Garritt ; Kocoloski, A. ; Koetke, Donald D. ; Kopytine, M. ; Korsch, W. ; Kotchenda, L. ; Kouchpil, V. ; Kravtsov, Peter ; Kravtsov, Vladimir I. ; Krueger, Keith William ; Krus, M. ; Kuhn, Christian Claude ; Kumar, Lokesh ; Kurnadi, P. ; Lamont, Matthew A. C. ; Landgraf, Jeffery M. ; LaPointe, S. ; Lauret, Jerome ; Lebedev, Alexei ; Lednicky, Richard ; Lee, C. -H. ; Lee, J. H. ; Leight, W. ; LeVine, Micheal J. ; Li, C. ; Li, N. ; Li, Y. ; Lin, G. ; Lindenbaum, Sam J. ; Lisa, Michael A. ; Liu, F. ; Liu, J. ; Liu, L. ; Ljubicic, Tonko A. ; Llope, William Joseph ; Longacre, Ronald S. ; Love, William A. ; Lu, Y. ; Ludlam, Thomas ; Ma, G. L. ; Ma, Yu-Gang ; Mahapatra, Durga Prasad ; Majka, Richard Daniel ; Mall, O. I. ; Mangotra, Lalit K. ; Manweiler, Robert W. ; Margetis, Spyridon ; Markert, Christina ; Matis, Howard S. ; Matulenko, Yuri A. ; McDonald, Daniel ; McShane, Tom S. ; Meščanin, Aleksei P. ; Milner, R. ; Minaev, Nikolai G. ; Mioduszewski, Saskia ; Mischke, André ; Mohanty, Bedangadas ; Morozov, Dmitry A. ; Munhoz, Marcelo Gameiro ; Nandi, Basanta Kumar ; Nattrass, Christine ; Nayak, Tapan Kumar ; Nelson, John M. ; Netrakanti, Pawan Kumar ; Ng, M. J. ; Nogach, Larisa V. ; Nurušev, Sandibek B. ; Odyniec, Grazyna Janina ; Ogawa, Akio ; Okada, H. ; Okorokov, Vitaly A. ; Olson, Douglas L. ; Pachr, Miloš ; Page, Brian S. ; Pal, Susanta Kumar ; Pandit, Y. ; Panebratsev, Yuri ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Perevoztchikov, V. ; Perkins, Chris ; Peryt, Wiktor Stanislaw ; Phatak, S. C. ; Pile, P. ; Planinic, Mirko ; Pluta, Jan Marian ; Plyku, D. ; Poljak, Nikola ; Poskanzer, Arthur M. ; Potukuchi, B. V. K. S. ; Prindle, Duncan J. ; Pruneau, Claude A. ; Pruthi, Navneet Kumar ; Pujahari, P. R. ; Putschke, Jörn H. ; Raniwala, Rashmi ; Raniwala, Sudhir ; Ray, Robert L. ; Redwine, R. ; Reed, Rosi Jan ; Ridiger, Alexey ; Ritter, Hans Georg ; Roberts, Jabus B. ; Rogačevskij, Oleg V. ; Romero, Juan L. ; Rose, A. ; Roy, Christelle Sophie ; Ruan, L. ; Russcher, M. J. ; Sahoo, Raghunath ; Sakrejda, Iwona ; Sakuma, T. ; Salur, Sevil ; Sandweiss, Jack H. ; Sarsour, M. ; Schambach, Joachim ; Scharenberg, Rolf Paul ; Schmitz, Norbert ; Seger, Janet Elizabeth ; Selyuzhenkov, Ilya ; Seyboth, Peter ; Shabetai, Alexandre ; Shahaliev, Ehtiram ; Shao, M. ; Sharma, M. ; Shi, Shusu ; Shi, X. -H. ; Sichtermann, Ernst P. ; Simon, F. ; Singaraju, Rama Narayana ; Skoby, Michael J. ; Smirnov, Nikolai ; Snellings, Raimond ; Sorensen, Paul Richard ; Sowinski, James ; Spinka, Harold. M. ; Srivastava, B. ; Stadnik, A. ; Stanislaus, T. D. Shirvel ; Staszak, D. ; Strichanov, Michail Nikolaevič ; Stringfellow, Blair ; Suaide, Alexandre Alarcon do Passo ; Suarez, M. C. ; Subba, N. L. ; Šumbera, Michal ; Sun, X. M. ; Sun, Y. ; Sun, Z. ; Surrow, Bernd ; Symons, Timothy James MacNeil ; de Toledo, A. Szanto ; Takahashi, Jun ; Tang, Aihong ; Tang, Zebo ; Tarini, L. H. ; Tarnowsky, Terence J. ; Thein, Dylan ; Thomas, James H. ; Tian, J. ; Timmins, Anthony Robert ; Timoshenko, Sergei ; Tlusty, David ; Tokarev, Mikhail V. ; Trainor, Thomas A. ; Tram, V. N. ; Trattner, A. L. ; Trentalange, Stephen ; Tribble, Robert E. ; Tsai, Oleg D. ; Ulery, Jason Glyndwr ; Ullrich, Thomas ; Underwood, David G. ; Van Buren, Gene ; Leeuwen, Marco van ; Molen, A. M. Vander ; Vanfossen, J. A. ; Varma, Raghava ; Vasconcelos, G. M. S. ; Vasilevski, I. M. ; Vasiliev, Alexander Nikolaevich ; Videbæk, Flemming ; Vigdor, Steven E. ; Viyogi, Yogendra P. ; Vokal, Stanislav ; Voloshin, Sergei ; Wada, M. ; Walker, M. ; Wang, F. ; Wang, G. ; Wang, J. S. ; Wang, Q. ; Wang, X. ; Wang, X. L. ; Wang, Y. ; Webb, Grant ; Webb, Jason C. ; Westfall, Gary D. ; Whitten, Charles A. ; Wieman, Howard ; Wissink, Scott W. ; Witt, Richard ; Wu, Y. ; Xie, W. ; Xu, N. ; Xu, Qinghua ; Xu, Y. ; Xu, Z. ; Yang, Y. ; Yepes, Pablo P. ; Yip, K. ; Yoo, I. -K. ; Yue, Q. ; Zawisza, M. ; Zbroszczyk, Hanna Paulina ; Zhan, W. ; Zhang, S. ; Zhang, W. M. ; Zhang, X. P. ; Zhang, Y. ; Zhang, Z. P. ; Zhao, Y. ; Zhong, C. ; Zhou, J. ; Zoulkarneev, R. ; Zoulkarneeva, Youlia ; Zuo, J. X.
The STAR Collaboration at the Relativistic Heavy Ion Collider presents measurements of 𝐽/𝜓→𝑒+𝑒− at midrapidity and high transverse momentum (𝑝𝑇>5 GeV/𝑐) in 𝑝+𝑝 and central Cu+Cu collisions at √𝑠𝑁𝑁=200 GeV. The inclusive 𝐽/𝜓 production cross section for Cu+Cu collisions is found to be consistent at high 𝑝𝑇 with the binary collision-scaled cross section for 𝑝+𝑝 collisions. At a confidence level of 97%, this is in contrast to a suppression of 𝐽/𝜓 production observed at lower 𝑝𝑇. Azimuthal correlations of 𝐽/𝜓 with charged hadrons in 𝑝+𝑝 collisions provide an estimate of the contribution of 𝐵-hadron decays to 𝐽/𝜓 production of 13%±5%.
Immunohistochemical assessment of phosphorylated mTORC1-pathway proteins in human brain tumors
(2015)
Harter, Patrick Nikolaus ; Jennewein, Lukas ; Baumgarten, Peter ; Ilina, Elena ; Burger, Michael Christian ; Thiepold, Anna-Luisa ; Tichy, Julia Frederike ; Zörnig, Martin ; Senft, Christian ; Steinbach, Joachim Peter ; Mittelbronn, Michel Guy André ; Ronellenfitsch, Michael Wilfried
Background: Current pathological diagnostics include the analysis of (epi-)genetic alterations as well as oncogenic pathways. Deregulated mammalian target of rapamycin complex 1 (mTORC1) signaling has been implicated in a variety of cancers including malignant gliomas and is considered a promising target in cancer treatment. Monitoring of mTORC1 activity before and during inhibitor therapy is essential. The aim of our study is to provide a recommendation and report on pitfalls in the use of phospho-specific antibodies against mTORC1-targets phospho-RPS6 (Ser235/236; Ser240/244) and phospho-4EBP1 (Thr37/46) in formalin fixed, paraffin embedded material.
Methods and findings: Primary, established cell lines and brain tumor tissue from routine diagnostics were assessed by immunocyto-, immunohistochemistry, immunofluorescent stainings and immunoblotting. For validation of results, immunoblotting experiments were performed. mTORC-pathway activation was pharmacologically inhibited by torin2 and rapamycin. Torin2 treatment led to a strong reduction of signal intensity and frequency of all tested antibodies. In contrast phospho-4EBP1 did not show considerable reduction in staining intensity after rapamycin treatment, while immunocytochemistry with both phospho-RPS6-specific antibodies showed a reduced signal compared to controls. Staining intensity of both phospho-RPS6-specific antibodies did not show considerable decrease in stability in a timeline from 0–230 minutes without tissue fixation, however we observed a strong decrease of staining intensity in phospho-4EBP1 after 30 minutes. Detection of phospho-signals was strongly dependent on tissue size and fixation gradient. mTORC1-signaling was significantly induced in glioblastomas although not restricted to cancer cells but also detectable in non-neoplastic cells.
Conclusion: Here we provide a recommendation for phospho-specific immunohistochemistry for patient-orientated therapy decisions and monitoring treatment response.
Vorobjev, Gleb ; Andre, Christiane ; Barth, Winfried ; Berdermann, Elèni ; Clemente, Gianluigi ; Ciobanu, Mircea Iuliu ; Dahl, Ludwig ; Forck, Peter ; Gerhard, Peter ; Haseitl, Rainer ; Herfurth, Frank ; Kaiser, Michael ; Kaufmann, Wolfgang ; Kester, Oliver ; Kluge, Heinz Jürgen ; Kotovski, Nikita ; Kozhuharov, Christophor ; Maier, Michael ; Quint, Wolfgang ; Reiter, Andreas ; Sokolov, Alexey ; Stöhlker, Thomas ; Pfister, Jochen ; Ratzinger, Ulrich ; Schempp, Alwin
The HITRAP linear decelerator currently being set up at GSI will provide slow, few keV/u highly charged ions for atomic physics experiments. The expected beam intensity is up to 105 ions per shot. To optimize phase and amplitude of the RF systems intensity, bunch length and kinetic energy of the particles need to be monitored. The bunch length that we need to fit is about 2 ns, which is typically measured by capacitive pickups. However, they do not work for the low beam intensities that we face. We investigated the bunch length with a fast CVD diamond detector working in single particle counting mode. Averaging over 8 shots yields a clear, regular picture of the bunched beam. Energy measurements by capacitive pickups are limited by the presence of intense primary and partially decelerated beam and hence make tuning of the IH-structure impossible. The energy of the decelerated fraction of the beam behind the first deceleration cavity was determined to about 10 % accuracy with a permanent dipole magnet combined with a MCP. Better detector calibration should help reaching the required 1%. Design of the detectors as well as the results of the measurements will be presented.
White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA Epilepsy study
(2019)
Hatton, Sean N. ; Huynh, Khoa H. ; Bonilha, Leonardo ; Abela, Eugenio Cecilio ; Alhusaini, Saud ; Altmann, André ; Alvim, Marina K. M. ; Balachandra, Akshara R. ; Bartolini, Emanuele ; Bender, Benjamin ; Bernasconi, Neda ; Bernasconi, Andrea ; Bernhardt, Boris ; Bargallo, Núria ; Caldairou, Benoit ; Caligiuri, Maria Eugenia ; Carr, Sarah J. A. ; Cavalleri, Gianpiero L. ; Cendes, Fernando ; Concha, Luis ; Davoodi-Bojd, Esmaeil ; Desmond, Patricia M. ; Devinsky, Orrin ; Doherty, Colin P. ; Domin, Martin ; Duncan, John S. ; Focke, Niels K. ; Foley, Sonya F. ; Gambardella, Antonio ; Gleichgerrcht, Ezequiel ; Guerrini, Renzo ; Hamandi, Khalid ; Ishikawa, Akari ; Keller, Simon S. ; Kochunov, Peter V. ; Kotikalapudi, Raviteja ; Kreilkamp, Barbara A. K. ; Kwan, Patrick ; Labate, Angelo ; Langner, Sönke ; Lenge, Matteo ; Liu, Min ; Lui, Elaine ; Martin, Pascal ; Mascalchi, Mario ; Moreira, José Carlos Vasques ; Morita-Sherman, Marcia Elisabete ; O’Brien, Terence J. ; Pardoe, Heath R. ; Pariente Zorrilla, José Carlos ; Ribeiro, Letı́cia F. ; Richardson, Mark Philip ; Rocha, Cristiane S. ; Rodrı́guez-Cruces, Raúl ; Rosenow, Felix ; Severino, Mariasavina ; Sinclair, Benjamin ; Soltanian-Zadeh, Hamid ; Striano, Pasquale ; Taylor, Peter N. ; Thomas, Rhys H. ; Tortora, Domenico ; Velakoulis, Dennis ; Vezzani, Annamaria ; Vivash, Lucy ; Podewils, Felix von ; Vos, Sjoerd B. ; Weber, Bernd ; Winston, Gavin P. ; Yasuda, Clarissa L. ; Thompson, Paul M. ; Jahanshad, Neda ; Sisodiya, Sanjay M. ; McDonald, Carrie R.
The epilepsies are commonly accompanied by widespread abnormalities in cerebral white matter. ENIGMA-Epilepsy is a large quantitative brain imaging consortium, aggregating data to investigate patterns of neuroimaging abnormalities in common epilepsy syndromes, including temporal lobe epilepsy, extratemporal epilepsy, and genetic generalized epilepsy. Our goal was to rank the most robust white matter microstructural differences across and within syndromes in a multicentre sample of adult epilepsy patients. Diffusion-weighted MRI data were analyzed from 1,069 non-epileptic controls and 1,249 patients: temporal lobe epilepsy with hippocampal sclerosis (N=599), temporal lobe epilepsy with normal MRI (N=275), genetic generalized epilepsy (N=182) and nonlesional extratemporal epilepsy (N=193). A harmonized protocol using tract-based spatial statistics was used to derive skeletonized maps of fractional anisotropy and mean diffusivity for each participant, and fiber tracts were segmented using a diffusion MRI atlas. Data were harmonized to correct for scanner-specific variations in diffusion measures using a batch-effect correction tool (ComBat). Analyses of covariance, adjusting for age and sex, examined differences between each epilepsy syndrome and controls for each white matter tract (Bonferroni corrected at p<0.001). Across “all epilepsies” lower fractional anisotropy was observed in most fiber tracts with small to medium effect sizes, especially in the corpus callosum, cingulum and external capsule. Less robust effects were seen with mean diffusivity. Syndrome-specific fractional anisotropy and mean diffusivity differences were most pronounced in patients with hippocampal sclerosis in the ipsilateral parahippocampal cingulum and external capsule, with smaller effects across most other tracts. Those with temporal lobe epilepsy and normal MRI showed a similar pattern of greater ipsilateral than contralateral abnormalities, but less marked than those in patients with hippocampal sclerosis. Patients with generalized and extratemporal epilepsies had pronounced differences in fractional anisotropy in the corpus callosum, corona radiata and external capsule, and in mean diffusivity of the anterior corona radiata. Earlier age of seizure onset and longer disease duration were associated with a greater extent of microstructural abnormalities in patients with hippocampal sclerosis. We demonstrate microstructural abnormalities across major association, commissural, and projection fibers in a large multicentre study of epilepsy. Overall, epilepsy patients showed white matter abnormalities in the corpus callosum, cingulum and external capsule, with differing severity across epilepsy syndromes. These data further define the spectrum of white matter abnormalities in common epilepsy syndromes, yielding new insights into pathological substrates that may be used to guide future therapeutic and genetic studies.
Scholz, Alexander ; Harter, Patrick Nikolaus ; Cremer, Sebastian ; Yalcin, Burak H. ; Gurnik, Stefanie ; Yamaji, Maiko ; Di Tacchio, Mariangela ; Sommer, Kathleen ; Baumgarten, Peter ; Bähr, Roy Oliver ; Steinbach, Joachim Peter ; Trojan, Jörg ; Glas, Martin ; Herrlinger, Ulrich ; Krex, Dietmar ; Meinhardt, Matthias ; Weyerbrock, Astrid ; Timmer, Marco ; Goldbrunner, Roland ; Deckert, Martina ; Braun, Christian ; Schittenhelm, Jens ; Früh, Jochen ; Ullrich, Evelyn ; Mittelbronn, Michel Guy André ; Plate, Karl ; Reiss, Yvonne
Glioblastoma multiforme (GBM) is treated by surgical resection followed by radiochemotherapy. Bevacizumab is commonly deployed for anti‐angiogenic therapy of recurrent GBM; however, innate immune cells have been identified as instigators of resistance to bevacizumab treatment. We identified angiopoietin‐2 (Ang‐2) as a potential target in both naive and bevacizumab‐treated glioblastoma. Ang‐2 expression was absent in normal human brain endothelium, while the highest Ang‐2 levels were observed in bevacizumab‐treated GBM. In a murine GBM model, VEGF blockade resulted in endothelial upregulation of Ang‐2, whereas the combined inhibition of VEGF and Ang‐2 leads to extended survival, decreased vascular permeability, depletion of tumor‐associated macrophages, improved pericyte coverage, and increased numbers of intratumoral T lymphocytes. CD206+ (M2‐like) macrophages were identified as potential novel targets following anti‐angiogenic therapy. Our findings imply a novel role for endothelial cells in therapy resistance and identify endothelial cell/myeloid cell crosstalk mediated by Ang‐2 as a potential resistance mechanism. Therefore, combining VEGF blockade with inhibition of Ang‐2 may potentially overcome resistance to bevacizumab therapy.
Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma
(2020)
Braun, Yannick ; Filipski, Katharina Johanna ; Bernatz, Simon ; Baumgarten, Peter ; Roller, Bastian ; Zinke, Jenny ; Zeiner, Pia Susan ; Ilina, Elena ; Senft, Christian ; Ronellenfitsch, Michael Wilfried ; Plate, Karl ; Bähr, Roy Oliver ; Hattingen, Elke ; Steinbach, Joachim Peter ; Mittelbronn, Michel Guy André ; Harter, Patrick Nikolaus
Aims: Changes in metabolism are known to contribute to tumour phenotypes. If and how metabolic alterations in brain tumours contribute to patient outcome is still poorly understood. Epigenetics impact metabolism and mitochondrial function. The aim of this study is a characterisation of metabolic features in molecular subgroups of isocitrate dehydrogenase mutant (IDHmut) and isocitrate dehydrogenase wildtype (IDHwt) gliomas. Methods: We employed DNA methylation pattern analyses with a special focus on metabolic genes, large-scale metabolism panel immunohistochemistry (IHC), qPCR-based determination of mitochondrial DNA copy number and immune cell content using IHC and deconvolution of DNA methylation data. We analysed molecularly characterised gliomas (n = 57) for in depth DNA methylation, a cohort of primary and recurrent gliomas (n = 22) for mitochondrial copy number and validated these results in a large glioma cohort (n = 293). Finally, we investigated the potential of metabolic markers in Bevacizumab (Bev)-treated gliomas (n = 29). Results: DNA methylation patterns of metabolic genes successfully distinguished the molecular subtypes of IDHmut and IDHwt gliomas. Promoter methylation of lactate dehydrogenase A negatively correlated with protein expression and was associated with IDHmut gliomas. Mitochondrial DNA copy number was increased in IDHmut tumours and did not change in recurrent tumours. Hierarchical clustering based on metabolism panel IHC revealed distinct subclasses of IDHmut and IDHwt gliomas with an impact on patient outcome. Further quantification of these markers allowed for the prediction of survival under anti-angiogenic therapy. Conclusion: A mitochondrial signature was associated with increased survival in all analyses, which could indicate tumour subgroups with specific metabolic vulnerabilities.
Lal, Dennis ; Ruppert, Ann-Kathrin ; Trucks, Holger ; Schulz, Herbert ; Kovel, Carolien G. de ; Kasteleijn-Nolst Trenité, Dorothée G. ; Sonsma, Anja C. M. ; Koeleman, Bobby P. ; Lindhout, Dick ; Weber, Yvonne G. ; Lerche, Holger ; Kapser, Claudia ; Schankin, Christoph Josef ; Kunz, Wolfram S. ; Surges, Rainer ; Elger, Christian Erich ; Gaus, Verena ; Schmitz, Bettina ; Helbig, Ingo ; Muhle, Hiltrud ; Stephani, Ulrich ; Klein, Karl Martin ; Rosenow, Felix ; Neubauer, Bernd Axel ; Reinthaler, Eva Maria ; Zimprich, Fritz ; Feucht, Martha ; Møller, Rikke S. ; Hjalgrim, Helle ; Jonghe, Peter De ; Suls, Arvid ; Lieb, Wolfgang ; Franke, Andre ; Strauch, Konstantin ; Gieger, Christian ; Schurmann, Claudia ; Schminke, Ulf ; Nürnberg, Peter ; Sander, Thomas
Genetic generalised epilepsy (GGE) is the most common form of genetic epilepsy, accounting for 20% of all epilepsies. Genomic copy number variations (CNVs) constitute important genetic risk factors of common GGE syndromes. In our present genome-wide burden analysis, large (≥ 400 kb) and rare (< 1%) autosomal microdeletions with high calling confidence (≥ 200 markers) were assessed by the Affymetrix SNP 6.0 array in European case-control cohorts of 1,366 GGE patients and 5,234 ancestry-matched controls. We aimed to: 1) assess the microdeletion burden in common GGE syndromes, 2) estimate the relative contribution of recurrent microdeletions at genomic rearrangement hotspots and non-recurrent microdeletions, and 3) identify potential candidate genes for GGE. We found a significant excess of microdeletions in 7.3% of GGE patients compared to 4.0% in controls (P = 1.8 x 10-7; OR = 1.9). Recurrent microdeletions at seven known genomic hotspots accounted for 36.9% of all microdeletions identified in the GGE cohort and showed a 7.5-fold increased burden (P = 2.6 x 10-17) relative to controls. Microdeletions affecting either a gene previously implicated in neurodevelopmental disorders (P = 8.0 x 10-18, OR = 4.6) or an evolutionarily conserved brain-expressed gene related to autism spectrum disorder (P = 1.3 x 10-12, OR = 4.1) were significantly enriched in the GGE patients. Microdeletions found only in GGE patients harboured a high proportion of genes previously associated with epilepsy and neuropsychiatric disorders (NRXN1, RBFOX1, PCDH7, KCNA2, EPM2A, RORB, PLCB1). Our results demonstrate that the significantly increased burden of large and rare microdeletions in GGE patients is largely confined to recurrent hotspot microdeletions and microdeletions affecting neurodevelopmental genes, suggesting a strong impact of fundamental neurodevelopmental processes in the pathogenesis of common GGE syndromes.
Jennewein, Lukas ; Ronellenfitsch, Michael Wilfried ; Antonietti, Patrick ; Ilina, Elena ; Jung, Jennifer ; Stadel, Daniela ; Flohr, Lisa-Marie ; Zinke, Jenny ; Renesse, Janusz von ; Drott, Ulrich ; Baumgarten, Peter ; Braczynski, Anne Kristin ; Penski, Cornelia ; Burger, Michael Christian ; Theurillat, Jean-Philippe ; Steinbach, Joachim Peter ; Plate, Karl ; Đikić, Ivan ; Fulda, Simone ; Brandts, Christian Hubertus ; Kögel, Donat ; Behrends, Christian ; Harter, Patrick Nikolaus ; Mittelbronn, Michel Guy André
Recently, the conserved intracellular digestion mechanism ‘autophagy’ has been considered to be involved in early tumorigenesis and its blockade proposed as an alternative treatment approach. However, there is an ongoing debate about whether blocking autophagy has positive or negative effects in tumor cells. Since there is only poor data about the clinico-pathological relevance of autophagy in gliomas in vivo, we first established a cell culture based platform for the in vivo detection of the autophago-lysosomal components. We then investigated key autophagosomal (LC3B, p62, BAG3, Beclin1) and lysosomal (CTSB, LAMP2) molecules in 350 gliomas using immunohistochemistry, immunofluorescence, immunoblotting and qPCR. Autophagy was induced pharmacologically or by altering oxygen and nutrient levels. Our results show that autophagy is enhanced in astrocytomas as compared to normal CNS tissue, but largely independent from the WHO grade and patient survival. A strong upregulation of LC3B, p62, LAMP2 and CTSB was detected in perinecrotic areas in glioblastomas suggesting micro-environmental changes as a driver of autophagy induction in gliomas. Furthermore, glucose restriction induced autophagy in a concentration-dependent manner while hypoxia or amino acid starvation had considerably lesser effects. Apoptosis and autophagy were separately induced in glioma cells both in vitro and in vivo. In conclusion, our findings indicate that autophagy in gliomas is rather driven by micro-environmental changes than by primary glioma-intrinsic features thus challenging the concept of exploitation of the autophago-lysosomal network (ALN) as a treatment approach in gliomas.
Rainger, Joe ; Beusekom, Ellen van ; Ramsay, Jacqueline K. ; McKie, Lisa ; Al-Gazali, Lihadh ; Pallotta, Rosanna ; Saponari, Anita ; Branney, Peter ; Fisher, Malcolm ; Morrison, Harris ; Bicknell, Louise ; Gautier, Philippe ; Perry, Paul ; Sokhi, Kishan ; Sexton, David ; Bardakjian, Tanya M. ; Schneider, Adele S. ; Elcioglu, Nursel ; Ozkinay, Ferda ; Koenig, Rainer ; Mégarbané, Andre ; Semerci, C. Nur ; Khan, Ayesha ; Zafar, Saemah ; Hennekam, Raoul C. ; Sousa, Sérgio B. ; Ramos, Lina ; Garavelli, Livia ; Furga, Andrea Superti ; Wischmeijer, Anita ; Jackson, Ian J. ; Gillessen-Kaesbach, Gabriele Gertrud ; Brunner, Han G. ; Wieczorek, Dagmar ; Bokhoven, Hans van ; FitzPatrick, David R.
Ophthalmo-acromelic syndrome (OAS), also known as Waardenburg Anophthalmia syndrome, is defined by the combination of eye malformations, most commonly bilateral anophthalmia, with post-axial oligosyndactyly. Homozygosity mapping and subsequent targeted mutation analysis of a locus on 14q24.2 identified homozygous mutations in SMOC1 (SPARC-related modular calcium binding 1) in eight unrelated families. Four of these mutations are nonsense, two frame-shift, and two missense. The missense mutations are both in the second Thyroglobulin Type-1 (Tg1) domain of the protein. The orthologous gene in the mouse, Smoc1, shows site- and stage-specific expression during eye, limb, craniofacial, and somite development. We also report a targeted pre-conditional gene-trap mutation of Smoc1 (Smoc1tm1a) that reduces mRNA to ~10% of wild-type levels. This gene-trap results in highly penetrant hindlimb post-axial oligosyndactyly in homozygous mutant animals (Smoc1tm1a/tm1a). Eye malformations, most commonly coloboma, and cleft palate occur in a significant proportion of Smoc1tm1a/tm1a embryos and pups. Thus partial loss of Smoc-1 results in a convincing phenocopy of the human disease. SMOC-1 is one of the two mammalian paralogs of Drosophila Pentagone, an inhibitor of decapentaplegic. The orthologous gene in Xenopus laevis, Smoc-1, also functions as a Bone Morphogenic Protein (BMP) antagonist in early embryogenesis. Loss of BMP antagonism during mammalian development provides a plausible explanation for both the limb and eye phenotype in humans and mice.
Seck, Peter von ; Sander, F. Martin ; Lanzendorf, Leon ; Seck, Sabine von ; Schmidt-Lucke, Jan André ; Zielonka, Mirja ; Schmidt-Lucke, Caroline
In evidence-based weight-loss programs weight regain is common after an initial weight reduction. Eating slowly significantly lowers meal energy intake and hunger ratings. Despite this knowledge, obese individuals do not implement this behaviour. We, thus tested the hypothesis of changing eating behaviour with an intra-oral medical device leading to constant weight reduction in overweight and obesity.
Six obese patients (6 men, age 56 ± 14, BMI 29 ± 2 kg / m2) with increased CVRF profile were included in this prospective study. All patients had been treated for obesity during the last 10 years in a single centre and had at least 3 frustrate evidence-based diets. Patients received a novel non-invasive intra-oral medical device to slow eating time. Further advice included not to count calories, to avoid any other form of diet, to take their time with their meals, and to eat whatever they liked.
This device was used only during meals for the first 4 to 8 weeks for a total of 88 [20–160] hours. Follow-up period was 23 [15–38] months. During this period, patients lost 11% [5–20%] (p<0.001) of their initial weight. At 12 months, all patients had lost >5%, and 67% (4/6) achieved a >10% bodyweight loss. In the course of the study, altered eating patterns were observed. There were no complications with the medical device. Of note, all patients continued to lose weight after the initial intervention period (p<0.001) and none of them had weight regain.
With this medical device, overweight and obese patients with a history of previously frustrating attempts to lose weight achieved a significant and sustained weight loss over two years. These results warrant the ongoing prospective randomised controlled trial to prove concept and mechanism of action.
Duplissy, Jonathan ; DeCarlo, Peter F. ; Dommen, Josef ; Alfarra, M. Rami ; Metzger, Axel ; Barmpadimos, Iakovos ; Prevot, André Stephan Henry ; Weingartner, Ernest ; Tritscher, Torsten ; Gysel, Martin ; Aiken, Allison C. ; Jimenez, Jose Luis ; Canagaratna, Manjula R. ; Worsnop, Douglas R. ; Collins, Donald R. ; Tomlinson, Jason M. ; Baltensperger, Urs
A hygroscopicity tandem differential mobility analyzer (HTDMA) was used to measure the water uptake (hygroscopicity) of secondary organic aerosol (SOA) formed during the chemical and photochemical oxidation of several organic precursors in a smog chamber. Electron ionization mass spectra of the non-refractory submicron aerosol were simultaneously determined with an aerosol mass spectrometer (AMS), and correlations between the two different signals were investigated. SOA hygroscopicity was found to strongly correlate with the relative abundance of the ion signal m/z 44 expressed as a fraction of total organic signal (f44). m/z 44 is due mostly to the ion fragment CO2+ for all types of SOA systems studied, and has been previously shown to strongly correlate with organic O/C for ambient and chamber OA. The analysis was also performed on ambient OA from two field experiments at the remote site Jungfraujoch, and the megacity Mexico City, where similar results were found. A simple empirical linear relation between the hygroscopicity of OA at subsaturated RH, as given by the hygroscopic growth factor (GF) or "ϰorg" parameter, and f44 was determined and is given by ϰorg = 2.2 × f44 − 0.13. This approximation can be further verified and refined as the database for AMS and HTDMA measurements is constantly being expanded around the world. The use of this approximation could introduce an important simplification in the parameterization of hygroscopicity of OA in atmospheric models, since f44 is correlated with the photochemical age of an air mass.
Eißmann, Moritz ; Schwamb, Bettina ; Melzer, Inga Maria ; Moser, Julia ; Siele, Dagmar ; Köhl, Ulrike ; Rieker, Ralf Joachim ; Wachter, David Lukas ; Agaimy, Abbas ; Herpel, Esther ; Baumgarten, Peter ; Mittelbronn, Michel Guy André ; Rakel, Stefanie ; Kögel, Donat ; Böhm, Stefanie ; Gutschner, Tony ; Diederichs, Sven ; Zörnig, Martin
Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a functional yeast survival screen that was used to isolate novel human anti-apoptotic genes overexpressed in treatment-resistant tumors. The screening of three different cDNA libraries prepared from metastatic melanoma, glioblastomas and leukemic blasts allowed for the identification of many yeast cell death-repressing cDNAs, including 28% of genes that are already known to inhibit apoptosis, 35% of genes upregulated in at least one tumor entity and 16% of genes described as both anti-apoptotic in function and upregulated in tumors. These results confirm the great potential of this screening tool to identify novel anti-apoptotic and tumor-relevant molecules. Three of the isolated candidate genes were further analyzed regarding their anti-apoptotic function in cell culture and their potential as a therapeutic target for molecular therapy. PAICS, an enzyme required for de novo purine biosynthesis, the long non-coding RNA MALAT1 and the MAST2 kinase are overexpressed in certain tumor entities and capable of suppressing apoptosis in human cells. Using a subcutaneous xenograft mouse model, we also demonstrated that glioblastoma tumor growth requires MAST2 expression. An additional advantage of the yeast survival screen is its universal applicability. By using various inducible pro-apoptotic killer proteins and screening the appropriate cDNA library prepared from normal or pathologic tissue of interest, the survival screen can be used to identify apoptosis inhibitors in many different systems.
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex
(2020)
Nürenberg-Goloub, Elina ; Kratzat, Hanna ; Heinemann, Holger ; Heuer, André ; Kötter, Peter ; Berninghausen, Otto ; Becker, Thomas ; Tampé, Robert ; Beckmann, Roland
Ribosome recycling by the twin-ATPase ABCE1 is a key regulatory process in mRNA translation and surveillance and in ribosome-associated protein quality control in Eukarya and Archaea. Here, we captured the archaeal 30S ribosome post-splitting complex at 2.8 Å resolution by cryo-electron microscopy. The structure reveals the dynamic behavior of structural motifs unique to ABCE1, which ultimately leads to ribosome splitting. More specifically, we provide molecular details on how conformational rearrangements of the iron–sulfur cluster domain and hinge regions of ABCE1 are linked to closure of its nucleotide-binding sites. The combination of mutational and functional analyses uncovers an intricate allosteric network between the ribosome, regulatory domains of ABCE1, and its two structurally and functionally asymmetric ATP-binding sites. Based on these data, we propose a refined model of how signals from the ribosome are integrated into the ATPase cycle of ABCE1 to orchestrate ribosome recycling.
Response to upfront azacitidine in juvenile myelomonocytic leukemia in the AZA-JMML-001 trial
(2021)
Niemeyer, Charlotte ; Flotho, Christian ; Lipka, Daniel ; Starý, Jan ; Rössig, Claudia ; Baruchel, André ; Klingebiel, Thomas ; Micalizzi, Concetta ; Michel, Gérard ; Nysom, Karsten ; Rives, Susana ; Schmugge Liner, Markus ; Zecca, Marco ; Schönung, Maximilian ; Baumann, Irith ; Nöllke, Peter ; Benettaib, Bouchra ; Biserna, Noha ; Poon, Jennifer ; Simcock, Mathew ; Patturajan, Meera ; Menezes, Daniel ; Gaudy, Allison ; Heuvel-Eibrink, Marry M. van den ; Locatelli, Franco
Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative therapy for most children with juvenile myelomonocytic leukemia (JMML). Novel therapies controlling the disorder prior to HSCT are needed. We conducted a phase 2, multicenter, open-label study to evaluate the safety and antileukemic activity of azacitidine monotherapy prior to HSCT in newly diagnosed JMML patients. Eighteen patients enrolled from September 2015 to November 2017 were treated with azacitidine (75 mg/m2) administered IV once daily on days 1 to 7 of a 28-day cycle. The primary end point was the number of patients with clinical complete remission (cCR) or clinical partial remission (cPR) after 3 cycles of therapy. Pharmacokinetics, genome-wide DNA-methylation levels, and variant allele frequencies of leukemia-specific index mutations were also analyzed. Sixteen patients completed 3 cycles and 5 patients completed 6 cycles. After 3 cycles, 11 patients (61%) were in cPR and 7 (39%) had progressive disease. Six of 16 patients (38%) who needed platelet transfusions were transfusion-free after 3 cycles. All 7 patients with intermediate- or low-methylation signatures in genome-wide DNA-methylation studies achieved cPR. Seventeen patients received HSCT; 14 (82%) were leukemia-free at a median follow-up of 23.8 months (range, 7.0-39.3 months) after HSCT. Azacitidine was well tolerated and plasma concentration-–time profiles were similar to observed profiles in adults. In conclusion, azacitidine monotherapy is a suitable option for children with newly diagnosed JMML. Although long-term safety and efficacy remain to be fully elucidated in this population, these data demonstrate that azacitidine provides valuable clinical benefit to JMML patients prior to HSCT. This trial was registered at www.clinicaltrials.gov as #NCT02447666.
Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma
(2018)
Ronellenfitsch, Michael Wilfried ; Zeiner, Pia Susan ; Mittelbronn, Michel Guy André ; Urban, Hans ; Pietsch, Torsten ; Reuter, Dirk ; Senft, Christian ; Steinbach, Joachim Peter ; Westphal, Manfred ; Harter, Patrick Nikolaus
Glioblastoma (GB) is the most frequent primary brain tumor in adults with a dismal prognosis despite aggressive treatment including surgical resection, radiotherapy and chemotherapy with the alkylating agent temozolomide. Thus far, the successful implementation of the concept of targeted therapy where a drug targets a selective alteration in cancer cells was mainly limited to model diseases with identified genetic drivers. One of the most commonly altered oncogenic drivers of GB and therefore plausible therapeutic target is the epidermal growth factor receptor (EGFR). Trials targeting this signaling cascade, however, have been negative, including the phase III OSAG 101-BSA-05 trial. This highlights the need for further patient selection to identify subgroups of GB with true EGFR-dependency. In this retrospective analysis of treatment-naïve samples of the OSAG 101-BSA-05 trial cohort, we identify the EGFR signaling activity markers phosphorylated PRAS40 and phosphorylated ribosomal protein S6 as predictive markers for treatment efficacy of the EGFR-blocking antibody nimotuzumab in MGMT promoter unmethylated GBs. Considering the total trial population irrespective of MGMT status, a clear trend towards a survival benefit from nimotuzumab was already detectable when tumors had above median levels of phosphorylated ribosomal protein S6. These results could constitute a basis for further investigations of nimotuzumab or other EGFR- and downstream signaling inhibitors in selected patient cohorts using the reported criteria as candidate predictive biomarkers.
Wirsik, Naita Maren ; Ehlers, Jakob ; Mäder, Lisa Victoria ; Ilina, Elena ; Blank, Anna-Eva ; Grote, Anne ; Feuerhake, Friedrich ; Baumgarten, Peter ; Devraj, Kavi ; Harter, Patrick Nikolaus ; Mittelbronn, Michel Guy André ; Naumann, Ulrike
Aims: In primary central nervous system tumours, epithelial-to-mesenchymal transition (EMT) gene expression is associated with increased malignancy. However, it has also been shown that EMT factors in gliomas are almost exclusively expressed by glioma vessel-associated pericytes (GA-Peris). In this study, we aimed to identify the mechanism of EMT in GA-Peris and its impact on angiogenic processes.
Methods; In glioma patients, vascular density and the expression of the pericytic markers platelet derived growth factor receptor (PDGFR)-β and smooth muscle actin (αSMA) were examined in relation to the expression of the EMT transcription factor SLUG and were correlated with survival of patients with glioblastoma (GBM). Functional mechanisms of SLUG regulation and the effects on primary human brain vascular pericytes (HBVP) were studied in vitro by measuring proliferation, cell motility and growth characteristics.
Results: The number of PDGFR-β- and αSMA-positive pericytes did not change with increased malignancy nor showed an association with the survival of GBM patients. However, SLUG-expressing pericytes displayed considerable morphological changes in GBM-associated vessels, and TGF-β induced SLUG upregulation led to enhanced proliferation, motility and altered growth patterns in HBVP. Downregulation of SLUG or addition of a TGF-β antagonising antibody abolished these effects.
Conclusions: We provide evidence that in GA-Peris, elevated SLUG expression is mediated by TGF-β, a cytokine secreted by most glioma cells, indicating that the latter actively modulate neovascularisation not only by modulating endothelial cells, but also by influencing pericytes. This process might be responsible for the formation of an unstructured tumour vasculature as well as for the breakdown of the blood–brain barrier in GBM.
Mönch, Christian ; Mihaljevic, Andre L. ; Hermanutz, Valentin ; Thasler, Wolfgang E. ; Suna, Kenan ; Diener, Markus K. ; Seehofer, Daniel ; Mischinger, Hans-Jörg ; Jansen-Winkeln, Boris ; Knaebel, Hanns-Peter ; Bechstein, Wolf Otto
Background: Despite improvements in liver surgery over the past decades, hemostasis during hepatic resections remains challenging. This multicenter randomized study compares the hemostatic effect of a collagen hemostat vs. a carrier-bound fibrin sealant after hepatic resection.
Methods: Patients scheduled for elective liver resection were randomized intraoperatively to receive either the collagen hemostat (COLL) or the carrier-bound fibrin sealant (CBFS) for secondary hemostasis. The primary endpoint was the proportion of patients with hemostasis after 3 min. Secondary parameters were the proportions of patients with hemostasis after 5 and 10 min, the total time to hemostasis, and the complication rates during a 3 months follow-up period.
Results: A total of 128 patients were included. In the COLL group, 53 out of 61 patients (86.9 %) achieved complete hemostasis within 3 min after application of the hemostat compared to 52 out of 65 patients (80.0 %) in the CBFS group. The 95 % confidence interval for this difference [−6.0 %, 19.8 %] does not include the lower noninferiority margin (−10 %). Thus, the COLL treatment can be regarded as noninferior to the comparator. The proportions of patients with hemostasis after 3, 5, and 10 min were not significantly different between the two study arms. Postoperative mortality and morbidity were similar in both treatment groups.
Conclusion: The collagen hemostat is as effective as the carrier-bound fibrin sealant in obtaining secondary hemostasis during liver resection with a comparable complication rate.
Jarick, Ivonne ; Volckmar, Anna-Lena ; Pütter, Carolin ; Pechlivanis, Sonali ; Nguyen, Trang T. ; Dauvermann, Maria R. ; Beck, Sebastian ; Albayrak, Özgür ; Scherag, Susann ; Gilsbach, Susanne ; Cichon, Sven ; Hoffmann, Per ; Degenhardt, Franziska ; Nöthen, Markus Maria ; Schreiber, Stefan ; Wichmann, Heinz Erich ; Jöckel, Karl-Heinz ; Heinrich, Joachim ; Tiesler, Carla Marie Thérèse ; Faraone, Stephen V. ; Walitza, Susanne ; Sinzig, Judith ; Freitag, Christine M. ; Meyer, Jobst ; Herpertz-Dahlmann, Beate ; Lehmkuh, Gerd ; Renner, Tobias J. ; Warnke, Andreas ; Romanos, Marcel ; Lesch, Klaus-Peter J. ; Reif, Andreas ; Schimmelmann, Benno G. ; Hebebrand, Johannes ; Scherag, André ; Hinney, Anke
Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurodevelopmental disorder. Genetic loci have not yet been identified by genome-wide association studies. Rare copy number variations (CNVs), such as chromosomal deletions or duplications, have been implicated in ADHD and other neurodevelopmental disorders. To identify rare (frequency ≤1%) CNVs that increase the risk of ADHD, we performed a whole-genome CNV analysis based on 489 young ADHD patients and 1285 adult population-based controls and identified one significantly associated CNV region. In tests for a global burden of large (>500 kb) rare CNVs, we observed a nonsignificant (P=0.271) 1.126-fold enriched rate of subjects carrying at least one such CNV in the group of ADHD cases. Locus-specific tests of association were used to assess if there were more rare CNVs in cases compared with controls. Detected CNVs, which were significantly enriched in the ADHD group, were validated by quantitative (q)PCR. Findings were replicated in an independent sample of 386 young patients with ADHD and 781 young population-based healthy controls. We identified rare CNVs within the parkinson protein 2 gene (PARK2) with a significantly higher prevalence in ADHD patients than in controls (P=2.8 × 10(-4) after empirical correction for genome-wide testing). In total, the PARK2 locus (chr 6: 162 659 756-162 767 019) harboured three deletions and nine duplications in the ADHD patients and two deletions and two duplications in the controls. By qPCR analysis, we validated 11 of the 12 CNVs in ADHD patients (P=1.2 × 10(-3) after empirical correction for genome-wide testing). In the replication sample, CNVs at the PARK2 locus were found in four additional ADHD patients and one additional control (P=4.3 × 10(-2)). Our results suggest that copy number variants at the PARK2 locus contribute to the genetic susceptibility of ADHD. Mutations and CNVs in PARK2 are known to be associated with Parkinson disease.
Hahn, Tim ; Marquand, Andre F. ; Plichta, Michael M. ; Ehlis, Ann-Christine ; Schecklmann, Martin ; Dresler, Thomas ; Jarczok, Tomasz Antoni ; Eirich, Elisa ; Leonhard, Christine ; Reif, Andreas ; Lesch, Klaus-Peter J. ; Brammer, Michael J. ; Mourão-Miranda, Janaina ; Fallgatter, Andreas Jochen
Pattern recognition approaches to the analysis of neuroimaging data have brought new applications such as the classification of patients and healthy controls within reach. In our view, the reliance on expensive neuroimaging techniques which are not well tolerated by many patient groups and the inability of most current biomarker algorithms to accommodate information about prior class frequencies (such as a disorder's prevalence in the general population) are key factors limiting practical application. To overcome both limitations, we propose a probabilistic pattern recognition approach based on cheap and easy-to-use multi-channel near-infrared spectroscopy (fNIRS) measurements. We show the validity of our method by applying it to data from healthy controls (n = 14) enabling differentiation between the conditions of a visual checkerboard task. Second, we show that high-accuracy single subject classification of patients with schizophrenia (n = 40) and healthy controls (n = 40) is possible based on temporal patterns of fNIRS data measured during a working memory task. For classification, we integrate spatial and temporal information at each channel to estimate overall classification accuracy. This yields an overall accuracy of 76% which is comparable to the highest ever achieved in biomarker-based classification of patients with schizophrenia. In summary, the proposed algorithm in combination with fNIRS measurements enables the analysis of sub-second, multivariate temporal patterns of BOLD responses and high-accuracy predictions based on low-cost, easy-to-use fNIRS patterns. In addition, our approach can easily compensate for variable class priors, which is highly advantageous in making predictions in a wide range of clinical neuroimaging applications. Hum Brain Mapp, 2013. © 2012 Wiley Periodicals, Inc.
Zeiner, Pia Susan ; Zinke, Jenny ; Kowalewski, Daniel Johannes ; Bernatz, Simon ; Tichy, Julia Frederike ; Ronellenfitsch, Michael Wilfried ; Thorsen, Frits ; Berger, Annemarie ; Forster, Marie-Thérèse ; Muller, Arnaud ; Steinbach, Joachim Peter ; Beschorner, Rudi ; Wischhusen, Jörg ; Kvasnicka, Hans Michael ; Plate, Karl ; Stefanovic, Stefan ; Weide, Benjamin ; Mittelbronn, Michel Guy André ; Harter, Patrick Nikolaus
Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of adaptive and innate anti-tumor response including the Human Leukocyte Antigen (HLA) machinery of antigen presentation is still unclear. We present data on the HLA class II-chaperone molecule CD74 in brain metastases and its impact on the HLA peptidome complexity.
We analyzed CD74 and HLA class II expression on tumor cells in a subset of 236 human brain metastases, primary tumors and peripheral metastases of different entities in association with clinical data including overall survival. Additionally, we assessed whole DNA methylome profiles including CD74 promoter methylation and differential methylation in 21 brain metastases. We analyzed the effects of a siRNA mediated CD74 knockdown on HLA-expression and HLA peptidome composition in a brain metastatic melanoma cell line.
We observed that CD74 expression on tumor cells is a strong positive prognostic marker in brain metastasis patients and positively associated with tumor-infiltrating T-lymphocytes (TILs). Whole DNA methylome analysis suggested that CD74 tumor cell expression might be regulated epigenetically via CD74 promoter methylation. CD74high and TILhigh tumors displayed a differential DNA methylation pattern with highest enrichment scores for antigen processing and presentation. Furthermore, CD74 knockdown in vitro lead to a reduction of HLA class II peptidome complexity, while HLA class I peptidome remained unaffected.
In summary, our results demonstrate that a functional HLA class II processing machinery in brain metastatic tumor cells, reflected by a high expression of CD74 and a complex tumor cell HLA peptidome, seems to be crucial for better patient prognosis.
Harter, Patrick Nikolaus ; Zinke, Jenny ; Scholz, Alexander ; Tichy, Julia Frederike ; Zachskorn, Cornelia ; Kvasnicka, Hans Michael ; Goeppert, Benjamin ; Delloye-Bourgeois, Céline ; Hattingen, Elke ; Senft, Christian ; Steinbach, Joachim Peter ; Plate, Karl ; Mehlen, Patrick ; Schulte, Dorothea ; Mittelbronn, Michel Guy André
The multifunctional molecule netrin-1 is upregulated in various malignancies and has recently been presented as a major general player in tumorigenesis leading to tumor progression and maintenance in various animal models. However, there is still a lack of clinico-epidemiological data related to netrin-1 expression. Therefore, the aim of our study was to elucidate the association of netrin-1 expression and patient survival in brain metastases since those constitute one of the most limiting factors for patient prognosis. We investigated 104 brain metastases cases for netrin-1 expression using in-situ hybridization and immunohistochemistry with regard to clinical parameters such as patient survival and MRI data. Our data show that netrin-1 is strongly upregulated in most cancer subtypes. Univariate analyses revealed netrin-1 expression as a significant factor associated with poor patient survival in the total cohort of brain metastasis patients and in sub-entities such as non-small cell lung carcinomas. Interestingly, many cancer samples showed a strong nuclear netrin-1 signal which was recently linked to a truncated netrin-1 variant that enhances tumor growth. Nuclear netrin-1 expression was associated with poor patient survival in univariate as well as in multivariate analyses. Our data indicate both total and nuclear netrin-1 expression as prognostic factors in brain metastases patients in contrast to other prognostic markers in oncology such as patient age, number of brain metastases or Ki67 proliferation index. Therefore, nuclear netrin-1 expression constitutes one of the first reported molecular biomarkers for patient survival in brain metastases. Furthermore, netrin-1 may constitute a promising target for future anti-cancer treatment approaches in brain metastases.
Rettinger, Eva ; Meyer, Vida ; Kreyenberg, Hermann ; Volk, Andreas ; Kuçi, Selim ; Willasch, Andre Manfred ; Koscielniak, Ewa ; Fulda, Simone ; Wels, Winfried ; Bönig, Halvard-Björn ; Klingebiel, Thomas ; Bader, Peter
Allogeneic stem cell transplantation (allo-SCT) has become an important treatment modality for patients with high-risk acute myeloid leukemia (AML) and is also under investigation for soft tissue sarcomas. The therapeutic success is still limited by minimal residual disease (MRD) status ultimately leading to patients’ relapse. Adoptive donor lymphocyte infusions based on MRD status using IL-15-expanded cytokine-induced killer (CIK) cells may prevent relapse without causing graft-versus-host-disease (GvHD). To generate preclinical data we developed mouse models to study anti-leukemic- and anti-tumor-potential of CIK cells in vivo. Immunodeficient mice (NOD/SCID/IL-2Rγc−, NSG) were injected intravenously with human leukemic cell lines THP-1, SH-2 and with human rhabdomyosarcoma (RMS) cell lines RH41 and RH30 at minimal doses required for leukemia or tumor engraftment. Mice transplanted with THP-1 or RH41 cells were randomly assigned for analysis of CIK cell treatment. Organs of mice were analyzed by flow cytometry as well as quantitative polymerase chain reaction for engraftment of malignant cells and CIK cells. Potential of CIK cells to induce GvHD was determined by histological analysis. Tissues of the highest degree of THP-1 cell expansion included bone marrow followed by liver, lung, spleen, peripheral blood (PB), and brain. RH30 and RH41 engraftment mainly took place in liver and lung, but was also detectable in spleen and PB. In spite of delayed CIK cell expansion compared with malignant cells, CIK cells injected at equal amounts were sufficient for significant reduction of RH41 cells, whereas against fast-expanding THP-1 cells 250 times more CIK than THP-1 cells were needed to achieve comparable results. Our preclinical in vivo mouse models showed a reliable 100% engraftment of malignant cells which is essential for analysis of anti-cancer therapy. Furthermore our data demonstrated that IL-15-activated CIK cells have potent cytotoxic capacity against AML and RMS cells without causing GvHD.
Ziel des Beitrags ist es, am Musterfall von Andreas Gryphius' 'Catharina von Georgien' (1657) - einem der bedeutendsten Texte der europäischen Barockliteratur - die politischen Implikationen zu beleuchten, die das Leiden der Märtyrerin im Trauerspiel des 17. Jahrhunderts begleiten. Den Leitfaden bildet dabei das Konzept der politischen Körperschaft, das Ernst H. Kantorowicz als Element der theologischen Herrscherlehre des Spätmittelalters beschrieben hat. Im Trauerspiel von Gryphius ist der Leib der Märtyrerin, so die These, keineswegs nur das Sinnbild einer am Modell der 'passio Christi' ausgerichteten Leidensgeschichte, sondern zugleich ein 'body politic' mit mystischer Bedeutung. Gryphius erzeugt diese Koinzidenz, indem er die Rollen der Königin, die als Interimsherrscherin amtiert und die des Opfers, das für den christlichen Glauben auf dem Scheiterhaufen stirbt, zusammenführt. Catharinas Leidensgeschichte erfüllt eine politische Mission, denn die blutige Zeugenschaft, die sie durch ihre 'passio' ablegt, dient dem Zweck der Sicherung eines übergeordneten Systems der Macht, das sie stellvertretend für ihren Sohn als Thronerben im Interregnum repräsentiert. Den Ausgangspunkt der folgenden Überlegungen bildet daher die Frage nach dem politisch-theologischen Hintergrund des Martyriums, das Catharina von Georgien bei Gryphius durchleidet.
PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells
(2011)
Lee, Sophia Boyoung ; Doberstein, Kai ; Baumgarten, Peter ; Wieland, Anja ; Ungerer, Christopher ; Bürger, Claudia ; Hardt, Katja ; Boehncke, Wolf-Henning ; Pfeilschifter, Josef ; Mihic-Probst, Daniela ; Mittelbronn, Michel Guy André ; Gutwein, Paul
PAX transcription factors play an important role during development and carcinogenesis. In this study, we investigated PAX2 protein levels in melanocytes and melanoma cells by Western Blot and immunofluorescence analysis and characterized the role of PAX2 in the pathogenesis of melanoma. In vitro we found weak PAX2 protein expression in keratinocytes and melanocytes. Compared to melanocytes increased PAX2 protein levels were detectable in melanoma cell lines. Interestingly, in tissue sections of melanoma patients nuclear PAX2 expression strongly correlated with nuclear atypia and the degree of prominent nucleoli, indicating an association of PAX2 with a more atypical cellular phenotype. In addition, with chromatin immunoprecipitation assay, PAX2 overexpression and PAX2 siRNA we present compelling evidence that PAX2 can regulate ADAM10 expression, a metalloproteinase known to play important roles in melanoma metastasis. In human tissue samples we found co-expression of PAX2 and ADAM10 in melanocytes of benign nevi and in melanoma cells of patients with malignant melanoma. Importantly, the downregulation of PAX2 by specific siRNA inhibited the anchorage independent cell growth and decreased the migratory and invasive capacity of melanoma cells. Furthermore, the downregulation of PAX2 abrogated the chemoresistance of melanoma cells against cisplatin, indicating that PAX2 expression mediates cell survival and plays important roles during melanoma progression.
Kuçi, Selim ; Rettinger, Eva ; Voß, Bernhard ; Weber, Gerrit ; Stais, Miriam ; Kreyenberg, Hermann ; Willasch, Andre Manfred ; Kuçi, Zyrafete ; Koscielniak, Ewa ; Klöß, Stephan ; Laer, Dorothee von ; Klingebiel, Thomas ; Bader, Peter
Background: Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines and investigated the mechanisms involved.
Design and Methods: Peripheral blood mononuclear cells from six healthy donors were used to generate and expand cytokine-induced killer cells. The phenotype and composition of these cells were determined by multiparameter flow cytometry, while their cytotoxic effect against rhabdomyosarcoma cells was evaluated by a europium release assay.
Results: Cytokine-induced killer cells efficiently lysed cells from both rhabdomyosarcoma cell lines. Antibody-mediated masking of either NKG2D molecule on cytokine-induced killer cells or its ligands on rhabdomyosarcoma cells (major histocompatibility antigen related chain A and B and UL16 binding protein 2) diminished this effect by 50%, suggesting a major role for the NKG2D molecule in rhabdomyosarcoma cell killing. No effect was observed after blocking CD11a, CD3 or TCRαβ molecules on cytokine-induced killer cells or CD1d on rhabdomyosar-coma cells. Remarkably, cytokine-induced killer cells used tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to activate caspase-3, as the main caspase responsible for the execution of apoptosis. Accordingly, blocking TRAIL receptors on embryonic rhabdomyosarcoma cell lines significantly reduced the anti-tumor effect of cytokine-induced killer cells. About 50% of T cells within the cytokine-induced killer population had an effector memory phenotype, 20% had a naïve phenotype and approximately 30% of the cells had a central memory phenotype. In addition, cytokine-induced killer cells expressed low levels of activation-induced markers CD69 and CD137 and demonstrated a low alloreactive potential.
Conclusions: Our data suggest that cytokine-induced killer cells may be used as a novel adoptive immunotherapy for the treatment of patients with rhabdomyosarcoma after allogeneic stem cell transplantation.