Characterization of neonates born to mothers with SARS-CoV-2 infection: review and meta-analysis
- Characterization of neonates born to mothers with SARS-CoV-2 infection has been partially carried out. There has been no systematic review providing a holistic neonatal presentation including possible vertical transmission. A systematic literature search was performed using PubMed, Google Scholar and Web of Science up to June, 6 2020. Studies on neonates born to mothers with SARS-CoV-2 infection were included. A binary random effect model was used for prevalence and 95% confidence interval. 32 studies involving 261 neonates were included in meta-analysis. Most neonates born to infected mothers did not show any clinical abnormalities (80.4%). Clinical features were dyspnea in 11 (42.3%) and fever in 9 newborns (19.1%). Of 261 neonates, 120 neonates were tested for infection, of whom 12 (10.0%) tested positive. Swabs from placenta, cord blood and vaginal secretion were negative. Neonates are mostly non affected by the mother's SARS-CoV-2 infection. The risk of vertical transmission is low.
Verfasserangaben: | Vanessa NeefORCiDGND, Horst BuxmannORCiDGND, Holger RabenauORCiDGND, Kai ZacharowskiORCiDGND, Florian RaimannORCiDGND |
---|---|
URN: | urn:nbn:de:hebis:30:3-575578 |
DOI: | https://doi.org/10.1016/j.pedneo.2020.10.001 |
ISSN: | 2212-1692 |
ISSN: | 1875-9572 |
Pubmed-Id: | https://pubmed.ncbi.nlm.nih.gov/33334687 |
Titel des übergeordneten Werkes (Englisch): | Pediatrics and neonatology |
Verlag: | Elsevier |
Verlagsort: | [Singapore] |
Dokumentart: | Wissenschaftlicher Artikel |
Sprache: | Englisch |
Datum der Veröffentlichung (online): | 24.10.2020 |
Datum der Erstveröffentlichung: | 24.10.2020 |
Veröffentlichende Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Datum der Freischaltung: | 23.12.2020 |
Freies Schlagwort / Tag: | COVID-19; SARS-CoV-2; infant; neonate; newborn |
Jahrgang: | 2020 |
Seitenzahl: | 10 |
HeBIS-PPN: | 476200474 |
Institute: | Medizin / Medizin |
DDC-Klassifikation: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Lizenz (Deutsch): | Creative Commons - Namensnennung-Nicht kommerziell - Keine Bearbeitung 4.0 |