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Über die UV-Bestrahlung von Desoxyribonucleinsäure in Glykol

  • Glycol causes a denaturation of the DNA double helix structure in solution. As could be shown earlier, heat denaturation of DNA leads to an increased dimerization of thymine following uvirradiation. In contrast to this, thymine dimer is not increased - but is even slightly decreased - when DNA is uv-irradiated in the presence of glycol. These results are discussed with regard to the distortion of the hydration layer and the hydrophobic stacking of bases, as influenced by glycol.

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Metadaten
Author:Hanswerner DellwegGND, Adolf WackerGND
URN:urn:nbn:de:hebis:30:3-713444
DOI:https://doi.org/10.1515/znb-1965-0210
ISSN:1865-7117
ISSN:0932-0776
Parent Title (German):Zeitschrift für Naturforschung, B
Publisher:Verlag der Zeitschrift für Naturforschung
Place of publication:Tübingen
Document Type:Article
Language:German
Date of Publication (online):2014/06/02
Year of first Publication:1965
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2023/07/14
Volume:20
Issue:2
Page Number:3
First Page:141
Last Page:143
HeBIS-PPN:512320187
Institutes:Biochemie, Chemie und Pharmazie / Biochemie und Chemie
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung 3.0