Analyzing the release of copeptin from the heart in acute myocardial infarction using a transcoronary gradient model

  • Copeptin is the C-terminal end of pre-provasopressin released equimolar to vasopressin into circulation and recently discussed as promising cardiovascular biomarker amendatory to established markers such as troponins. Vasopressin is a cytokine synthesized in the hypothalamus. A direct release of copeptin from the heart into the circulation is implied by data from a rat model showing a cardiac origin in hearts put under cardiovascular wall stress. Therefore, evaluation of a potential release of copeptin from the human heart in acute myocardial infarction (AMI) has been done.

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Author:Jes-Niels Boeckel, Jana Oppermann, Remzi Anadol, Stephan Fichtlscherer, Andreas M. ZeiherORCiDGND, Till KellerORCiDGND
Pubmed Id:
Parent Title (English):Scientific Reports
Document Type:Article
Date of Publication (online):2016/12/20
Date of first Publication:2016/02/11
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2016/12/21
Page Number:5
First Page:1
Last Page:5
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Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung 4.0