Tracking daily fatigue fluctuations in multiple sclerosis : ecological momentary assessment provides unique insights
- Studies investigating the prevalence, cause, and consequence of multiple sclerosis (MS) fatigue typically use single measures that implicitly assume symptom-stability over time, neglecting information about if, when, and why severity fluctuates. We aimed to examine the extent of moment-to-moment and day-to-day variability in fatigue in relapsing-remitting MS and healthy individuals, and identify daily life determinants of fluctuations. Over 4 weekdays, 76 participants (38 relapsing-remitting MS; 38 controls) recruited from multiple sites provided real-time self-reports six times daily (n = 1661 observations analyzed) measuring fatigue severity, stressors, mood, and physical exertion, and daily self-reports of sleep quality. Fatigue fluctuations were evident in both groups. Fatigue was highest in relapsing-remitting MS, typically peaking in late-afternoon. In controls, fatigue started lower and increased steadily until bedtime. Real-time stressors and negative mood were associated with increased fatigue, and positive mood with decreased fatigue in both groups. Increased fatigue was related to physical exertion in relapsing-remitting MS, and poorer sleep quality in controls. In relapsing-remitting MS, fatigue fluctuates substantially over time. Many daily life determinants of fluctuations are similar in relapsing-remitting MS and healthy individuals (stressors, mood) but physical exertion seems more relevant in relapsing-remitting MS and sleep quality most relevant in healthy individuals.
Author: | Daniel J. H. Powell, Christina Liossi, Wolff Schlotz, Rona Moss-Morris |
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URN: | urn:nbn:de:hebis:30:3-468157 |
DOI: | https://doi.org/10.1007/s10865-017-9840-4 |
DOI: | https://doi.org/28281106 |
ISSN: | 1573-3521 |
ISSN: | 0160-7715 |
Parent Title (English): | Journal of behavioral medicine |
Publisher: | Springer Science + Business Media B.V. |
Place of publication: | Dordrecht [u. a.] |
Document Type: | Article |
Language: | English |
Year of Completion: | 2017 |
Date of first Publication: | 2017/03/09 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2018/06/21 |
Tag: | Affect; Ambulatory assessment; Ecological momentary assessment; Fatigue; Multiple sclerosis; Psychological stress |
Volume: | 40 |
Issue: | 5 |
Page Number: | 12 |
First Page: | 772 |
Last Page: | 783 |
Note: | © The Author(s) 2017. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
HeBIS-PPN: | 434441570 |
Institutes: | Psychologie und Sportwissenschaften / Psychologie |
Angeschlossene und kooperierende Institutionen / MPI für empirische Ästhetik | |
Dewey Decimal Classification: | 1 Philosophie und Psychologie / 15 Psychologie / 150 Psychologie |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung 4.0 |