Liliya Doronina, Graham M. Hughes, Diana Moreno-Santillan, Colleen Lawless, Tadhg Lonergan, Louise Ryan, David Jebb, Bogdan M. Kirilenko, Jennifer M. Korstian, Liliana M. Dávalos, Sonja C. Vernes, Eugene W. Myers, Emma C. Teeling, Michael Hiller, Lars S. Jermiin, Jürgen Schmitz, Mark S. Springer, David A. Ray
- Relationships among laurasiatherian clades represent one of the most highly disputed topics in mammalian phylogeny. In this study, we attempt to disentangle laurasiatherian interordinal relationships using two independent genome-level approaches: (1) quantifying retrotransposon presence/absence patterns, and (2) comparisons of exon datasets at the levels of nucleotides and amino acids. The two approaches revealed contradictory phylogenetic signals, possibly due to a high level of ancestral incomplete lineage sorting. The positions of Eulipotyphla and Chiroptera as the first and second earliest divergences were consistent across the approaches. However, the phylogenetic relationships of Perissodactyla, Cetartiodactyla, and Ferae, were contradictory. While retrotransposon insertion analyses suggest a clade with Cetartiodactyla and Ferae, the exon dataset favoured Cetartiodactyla and Perissodactyla. Future analyses of hitherto unsampled laurasiatherian lineages and synergistic analyses of retrotransposon insertions, exon and conserved intron/intergenic sequences might unravel the conflicting patterns of relationships in this major mammalian clade.
MetadatenAuthor: | Liliya DoroninaORCiDGND, Graham M. HughesORCiD, Diana Moreno-SantillanORCiD, Colleen LawlessORCiD, Tadhg LonerganORCiD, Louise RyanORCiD, David Jebb, Bogdan M. KirilenkoORCiDGND, Jennifer M. Korstian, Liliana M. DávalosORCiDGND, Sonja C. VernesORCiD, Eugene W. MyersORCiD, Emma C. TeelingORCiD, Michael HillerORCiDGND, Lars S. JermiinORCiD, Jürgen SchmitzORCiDGND, Mark S. Springer, David A. RayORCiD |
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URN: | urn:nbn:de:hebis:30:3-692445 |
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DOI: | https://doi.org/10.3390/genes13050766 |
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ISSN: | 2073-4425 |
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Parent Title (English): | Genes |
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Publisher: | MDPI |
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Place of publication: | Basel |
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Document Type: | Article |
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Language: | English |
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Date of Publication (online): | 2022/04/26 |
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Date of first Publication: | 2022/04/26 |
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Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
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Release Date: | 2022/12/19 |
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Tag: | Laurasiatheria; Scrotifera; anomaly zone; exon coalescence; exon concatenation; retrophylogenomics |
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Volume: | 13 |
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Issue: | 5, art. 766 |
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Article Number: | 766 |
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Page Number: | 17 |
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First Page: | 1 |
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Last Page: | 17 |
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Note: | Data Availability Statement
All retrotransposon data are presented in Supplementary Materials. The exon DNA and amino acid alignments and individual gene trees are deposited at https://figshare.com/s/b0bca1ca0f8328ec993a (accessed on 28 March 2022). |
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Institutes: | Biowissenschaften |
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Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
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Sammlungen: | Universitätspublikationen |
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Licence (German): | Creative Commons - CC BY - Namensnennung 4.0 International |
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