Hämoproteinoide mit peroxidatischer und katalatischer Aktivität
The peroxidatic and catalatic activity of hemoproteinoids
- Hemoproteinoids related to contemporary porphyrin-dependent peroxidases were synthesized under simple conditions. The peroxidative activity of hematin increased by a factor of 50 if the hematin was bound to proteinoids whereas the catalatic activity of hematin decreased rather under the same conditions. The peroxidative activity of hemoproteinoids particularly increased with their lysine content whereas the catalatic activity especially decreased in proteinoids with high phenylalanine content. The isoelectric points of the lysine-rich peroxidic hemoproteinoids were about 8. Their relatively broad pH-activity optimum was about pH 7.0. The molecular weights were a little below 20 000. Hematin content and amino acid composition of the synthetic materials were varied greatly. The substrate specificity appeared as broad as that of biogenous peroxidases, e. g., horseradish peroxidase. Among the many substrates was NADH. The possible importance of the peroxidative oxidation of NADH-type coenzymes by primitive heterotrophic organisms or prebiological systems in an anaerobic environment is discussed.
Author: | Klaus DoseGND, Laila Zaki Mohamed AhmedGND |
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URN: | urn:nbn:de:hebis:30:3-714956 |
DOI: | https://doi.org/10.1515/znb-1971-0218 |
ISSN: | 1865-7117 |
ISSN: | 0932-0776 |
Parent Title (German): | Zeitschrift für Naturforschung, B |
Publisher: | Verlag der Zeitschrift für Naturforschung |
Place of publication: | Tübingen |
Document Type: | Article |
Language: | German |
Date of Publication (online): | 2014/06/02 |
Year of first Publication: | 1971 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2023/07/28 |
Volume: | 26 |
Issue: | 2 |
Page Number: | 5 |
First Page: | 144 |
Last Page: | 148 |
HeBIS-PPN: | 512583781 |
Institutes: | Biochemie, Chemie und Pharmazie / Biochemie und Chemie |
Angeschlossene und kooperierende Institutionen / MPI für Biophysik | |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie | |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung 3.0 |