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Oxidative folding of proteins: the 'smoking gun' of glutathione

  • Glutathione has long been suspected to be the primary low molecular weight compound present in all cells promoting the oxidative protein folding, but twenty years ago it was found “not guilty”. Now, new surprising evidence repeats its request to be the “smoking gun” which reopens the criminal trial revealing the crucial involvement of this tripeptide.

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Author:Alessio Bocedi, Giada Cattani, Giorgia Gambardella, Linda Schulte, Harald SchwalbeORCiDGND, Giorgio Ricci
URN:urn:nbn:de:hebis:30:3-621756
DOI:https://doi.org/10.3390/ijms221810148
ISSN:1422-0067
Parent Title (English):International journal of molecular sciences
Publisher:MDPI
Place of publication:Basel
Document Type:Article
Language:English
Date of Publication (online):2021/09/20
Date of first Publication:2021/09/20
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2022/03/02
Tag:cysteine reactivity; glutathione; glutathionylation; nitrosylation; oxidative folding; ribosomal exit tunnel; transient complex
Volume:22
Issue:8, art. 10148
Page Number:6
First Page:1
Last Page:6
HeBIS-PPN:49205116X
Institutes:Biochemie, Chemie und Pharmazie
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0