A comparison of third-generation semi-invasive arterial waveform analysis with thermodilution in patients undergoing coronary surgery

  • Uncalibrated semi-invasive continous monitoring of cardiac index (CI) has recently gained increasing interest. The aim of the present study was to compare the accuracy of CI determination based on arterial waveform analysis with transpulmonary thermodilution. Fifty patients scheduled for elective coronary surgery were studied after induction of anaesthesia and before and after cardiopulmonary bypass (CPB), respectively. Each patient was monitored with a central venous line, the PiCCO system, and the FloTrac/Vigileo-system. Measurements included CI derived by transpulmonary thermodilution and uncalibrated semi-invasive pulse contour analysis. Percentage changes of CI were calculated. There was a moderate, but significant correlation between pulse contour CI and thermodilution CI both before (r(2) = 0.72, P < 0.0001) and after (r(2) = 0.62, P < 0.0001) CPB, with a percentage error of 31% and 25%, respectively. Changes in pulse contour CI showed a significant correlation with changes in thermodilution CI both before (r(2) = 0.52, P < 0.0001) and after (r(2) = 0.67, P < 0.0001) CPB. Our findings demonstrated that uncalibrated semi-invasive monitoring system was able to reliably measure CI compared with transpulmonary thermodilution in patients undergoing elective coronary surgery. Furthermore, the semi-invasive monitoring device was able to track haemodynamic changes and trends.

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Author:Ole Broch, Jochen Renner, Matthias Lars Grünewald, Patrick MeybohmORCiDGND, Jan Schöttler, Markus Steinfath, Manu Malbrain, Berthold Bein
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/22919321
Parent Title (English):The ScientificWorld journal
Place of publication:Boynton Beach, Fla.
Document Type:Article
Date of Publication (online):2012/07/31
Date of first Publication:2012/07/31
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2013/02/25
Issue:Article ID 451081
Page Number:7
Copyright © 2012 Ole Broch et al. This is an open access article distributed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung 3.0