Advances in antibody-based hiv-1 vaccines development

  • Despite the great success of antiretroviral therapy, both in the treatment and prevention of HIV-1 infection, a vaccine is still urgently needed to end the epidemic. According to UNAIDS, in 2018, about 35% of HIV-1 infected persons did not receive antiretroviral therapy (ART), resulting in 1.7 million new infections in that year. One major reason for actual HIV-1 transmissions is the fact that about 20% of HIV- 1 infected persons do not know about their HIV-positive status and therefore are not on ART despite the potential high viral load linked to high risk of virus transmission. Therefore, in particular in countries with high HIV incidence, a preventive vaccine is required to reduce HIV transmissions in the general population. In this special issue of Vaccines, invited experts contribute a series of articles to the current understanding of antibody-based HIV-1 vaccine development. ...

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Author:Ursula Dietrich
URN:urn:nbn:de:hebis:30:3-531382
DOI:https://doi.org/10.3390/vaccines8010044
ISSN:2076-393X
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/31991723
Parent Title (English):Vaccines
Publisher:MDPI
Place of publication:Basel
Document Type:Article
Language:English
Year of Completion:2020
Date of first Publication:2020/01/25
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2020/03/18
Volume:8
Issue:1, Art. 44
Page Number:4
First Page:1
Last Page:4
Note:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
HeBIS-PPN:463785355
Institutes:Angeschlossene und kooperierende Institutionen / Georg-Speyer-Haus
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0