Multidrug-resistant organisms (MDROs) in patients with subarachnoid hemorrhage (SAH)
- Patient care in a neurointensive care unit (neuro-ICU) is challenging. Multidrug-resistant organisms (MDROs) are increasingly common in the routine clinical practice. We evaluated the impact of infection with MDROs on outcomes in patients with subarachnoid hemorrhage (SAH). A single-center retrospective analysis of SAH cases involving patients treated in the neuro-ICU was performed. The outcome was assessed 6 months after SAH using the modified Rankin Scale [mRS, favorable (0–2) and unfavorable (3–6)]. Data were compared by matched-pair analysis. Patient characteristics were well matched in the MDRO (n = 61) and control (n = 61) groups. In this center, one nurse was assigned to a two-bed room. If a MDRO was detected, the patient was isolated, and the nurse was assigned to the patient infected with the MDRO. In the MDRO group, 29 patients (48%) had a favorable outcome, while 25 patients (41%) in the control group had a favorable outcome; the difference was not significant (p > 0.05). Independent prognostic factors for unfavorable outcomes were worse status at admission (OR = 3.1), concomitant intracerebral hematoma (ICH) (OR = 3.7), and delayed cerebral ischemia (DCI) (OR = 6.8). Infection with MRDOs did not have a negative impact on the outcome in SAH patients. Slightly better outcomes were observed in SAH patients infected with MDROs, suggesting the benefit of individual care.
Author: | Ha-Young RhimGND, Sae-Yeon WonORCiDGND, Sepide KashefiolaslORCiDGND, Nina BrawanskiORCiDGND, Elke HattingenORCiDGND, Joachim BerkefeldORCiDGND, Volker SeifertORCiD, Jürgen KonczallaORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-637114 |
DOI: | https://doi.org/10.1038/s41598-021-87863-y |
ISSN: | 2045-2322 |
Parent Title (English): | Scientific reports |
Publisher: | Macmillan Publishers Limited, part of Springer Nature |
Place of publication: | [London] |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2021/04/15 |
Date of first Publication: | 2021/04/15 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2022/11/08 |
Tag: | Health care; Medical research; Neurology |
Volume: | 11 |
Issue: | art. 8309 |
Article Number: | 8309 |
Page Number: | 7 |
First Page: | 1 |
Last Page: | 7 |
Note: | Open Access funding enabled and organized by Projekt DEAL. |
HeBIS-PPN: | 507123271 |
Institutes: | Medizin |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung 4.0 |