Multidrug-resistant organisms (MDROs) in patients with subarachnoid hemorrhage (SAH)

  • Patient care in a neurointensive care unit (neuro-ICU) is challenging. Multidrug-resistant organisms (MDROs) are increasingly common in the routine clinical practice. We evaluated the impact of infection with MDROs on outcomes in patients with subarachnoid hemorrhage (SAH). A single-center retrospective analysis of SAH cases involving patients treated in the neuro-ICU was performed. The outcome was assessed 6 months after SAH using the modified Rankin Scale [mRS, favorable (0–2) and unfavorable (3–6)]. Data were compared by matched-pair analysis. Patient characteristics were well matched in the MDRO (n = 61) and control (n = 61) groups. In this center, one nurse was assigned to a two-bed room. If a MDRO was detected, the patient was isolated, and the nurse was assigned to the patient infected with the MDRO. In the MDRO group, 29 patients (48%) had a favorable outcome, while 25 patients (41%) in the control group had a favorable outcome; the difference was not significant (p > 0.05). Independent prognostic factors for unfavorable outcomes were worse status at admission (OR = 3.1), concomitant intracerebral hematoma (ICH) (OR = 3.7), and delayed cerebral ischemia (DCI) (OR = 6.8). Infection with MRDOs did not have a negative impact on the outcome in SAH patients. Slightly better outcomes were observed in SAH patients infected with MDROs, suggesting the benefit of individual care.

Download full text files

Export metadata

Metadaten
Author:Ha-Young RhimGND, Sae-Yeon WonORCiDGND, Sepide KashefiolaslGND, Nina BrawanskiGND, Elke HattingenORCiDGND, Joachim BerkefeldGND, Volker Seifert, Jürgen KonczallaORCiDGND
URN:urn:nbn:de:hebis:30:3-637114
DOI:https://doi.org/10.1038/s41598-021-87863-y
ISSN:2045-2322
Parent Title (English):Scientific reports
Publisher:Macmillan Publishers Limited, part of Springer Nature
Place of publication:[London]
Document Type:Article
Language:English
Date of Publication (online):2021/04/15
Date of first Publication:2021/04/15
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2022/11/08
Tag:Health care; Medical research; Neurology
Volume:11
Issue:art. 8309
Article Number:8309
Page Number:7
First Page:1
Last Page:7
Note:
Open Access funding enabled and organized by Projekt DEAL.
Institutes:Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0