Biochemistry of methanol-dependent acetogenesis in Eubacterium callanderi KIST612

  • Methanol is the simplest of all alcohols, is universally distributed in anoxic sediments as a result of plant material decomposition and is constantly attracting attention as an interesting substrate for anaerobes like acetogens that can convert bio-renewable methanol into value-added chemicals. A major drawback in the development of environmentally friendly but economically attractive biotechnological processes is the present lack of information on biochemistry and bioenergetics during methanol conversion in these bacteria. The mesophilic acetogen Eubacterium callanderi KIST612 is naturally able to consume methanol and produce acetate as well as butyrate. To grasp the full potential of methanol-based production of chemicals, we analysed the genes and enzymes involved in methanol conversion to acetate and identified the redox carriers involved. We will display a complete model for methanol-derived acetogenesis and butyrogenesis in Eubacterium callanderi KIST612, tracing the electron transfer routes and shed light on the bioenergetics during the process.
Metadaten
Author:Helge M. Dietrich, Florian Kremp, Christian Manfred ÖppingerGND, Luna Ribaric, Volker MüllerORCiD
URN:urn:nbn:de:hebis:30:3-639201
DOI:https://doi.org/10.1111/1462-2920.15643
ISSN:1462-2920
Parent Title (English):Environmental microbiology
Publisher:Blackwell
Place of publication:Oxford [u.a.]
Document Type:Article
Language:English
Date of Publication (online):2021/06/14
Date of first Publication:2021/06/14
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2022/04/05
Volume:23
Issue:8
Page Number:13
First Page:4505
Last Page:4517
Note:
Financial support by the European Research Area Cofund on BioTechnologies (ERA CoBioTech; project BIOMETCHEM) is gratefully acknowledged.
HeBIS-PPN:493708057
Institutes:Biowissenschaften
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0