Impact of DMEK on visual quality in patients with Fuchs' endothelial dystrophy
- Purpose: To investigate short-term (3 months follow-up) changes in visual quality following Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy (FED). Methods: In this prospective institutional case series, 51 patients that underwent DMEK for FED were included. Assessment included the Quality of Vision (QoV) questionnaire preoperatively, at 1 month, and 3 months after surgery. Secondary outcome measures were anterior segment parameters acquired by Scheimpflug imaging, corrected distance visual acuity (CDVA), and endothelial cell density (ECD). Results: Glare, hazy vision, blurred vision, and daily fluctuation in vision were the symptoms mostly reported preoperatively. All symptoms demonstrated a significant reduction of item scores for severity, frequency, and bothersome in the course after DMEK (P < 0.01). Glare and fluctuation in vision remained to some extent during the follow-up period (median score = 1). Preoperatively, corneal densitometry correlated moderately to weakly with severity of hazy vision (rs = 0.39; P = 0.03) and frequency (rs = 0.26; P = 0.02) as well as severity (rs = 0.27; P = 0.03) of blurry vision. CDVA and central corneal thickness (CCT) did not correlate with visual complains. Conclusions: Following DMEK for FED, patient-reported visual symptoms assessed by the QoV questionnaire represent a useful tool providing valuable information on the impact of DMEK on visual quality that cannot be directly estimated by morphological parameters and visual acuity only.
Author: | Vanessa Ademmer, Bishr AghaGND, Mehdi ShajariGND, Thomas KohnenORCiDGND, Ingo SchmackORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-640177 |
DOI: | https://doi.org/10.1007/s00417-021-05334-6 |
ISSN: | 1435-702X |
Parent Title (English): | Graefe's archive for clinical and experimental ophthalmology |
Publisher: | Springer |
Place of publication: | Berlin ; Heidelberg |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2021/09/16 |
Date of first Publication: | 2021/09/16 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2022/01/11 |
Tag: | DMEK; Fuchs endothelial dystrophy; Scheimpflug imaging; Visual quality |
Volume: | 2021 |
Issue: | online version before inclusion in an issue |
Page Number: | 8 |
Note: | Early View: Online Version before inclusion in an issue. |
HeBIS-PPN: | 491319711 |
Institutes: | Medizin |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung 4.0 |