Refine
Year of publication
Document Type
- Article (5324)
- Doctoral Thesis (1502)
- Part of Periodical (211)
- Conference Proceeding (189)
- Preprint (171)
- Book (86)
- Contribution to a Periodical (67)
- Review (50)
- Working Paper (22)
- Part of a Book (17)
Language
Keywords
- inflammation (80)
- COVID-19 (60)
- SARS-CoV-2 (48)
- apoptosis (38)
- cancer (38)
- glioblastoma (38)
- Inflammation (37)
- breast cancer (34)
- autophagy (29)
- prostate cancer (28)
- Cancer (26)
- Apoptosis (25)
- Depression (25)
- Epilepsy (23)
- biomarker (23)
- immunotherapy (23)
- macrophage (23)
- ADHD (22)
- Video (21)
- HIV (20)
- microRNA (20)
- chemotherapy (19)
- epilepsy (19)
- hypoxia (19)
- mitochondria (19)
- pain (19)
- Biomarker (18)
- Breast cancer (18)
- MRI (18)
- Quality of life (18)
- aging (18)
- children (18)
- data science (18)
- depression (18)
- reactive oxygen species (17)
- Germany (16)
- Stroke (16)
- Surgery (16)
- Treatment (16)
- angiogenesis (16)
- glioma (16)
- prevention (16)
- proliferation (16)
- stroke (16)
- Cirrhosis (15)
- Neuroscience (15)
- Outcome (15)
- endothelial cells (15)
- fMRI (15)
- mTOR (15)
- quality of life (15)
- treatment (15)
- tumor microenvironment (15)
- Genetics (14)
- diagnosis (14)
- mortality (14)
- multiple sclerosis (14)
- obesity (14)
- radical prostatectomy (14)
- schizophrenia (14)
- Angiogenesis (13)
- Biomarkers (13)
- Capsule endoscopy (13)
- Deutschland (13)
- Diagnostik (13)
- Human behaviour (13)
- Magnetic resonance imaging (13)
- Mammakarzinom (13)
- Mortality (13)
- NADPH oxidase (13)
- Oncology (13)
- Radiotherapy (13)
- attention (13)
- bladder cancer (13)
- cirrhosis (13)
- cytokines (13)
- epidemiology (13)
- lung cancer (13)
- macrophages (13)
- EEG (12)
- Gene expression (12)
- Immunotherapy (12)
- Mitochondria (12)
- Prävention (12)
- ROS (12)
- Sepsis (12)
- miRNA (12)
- survival (12)
- targeted therapy (12)
- Chemotherapy (11)
- Endoscopy (11)
- Immunology (11)
- Machine learning (11)
- PCR (11)
- Parkinson’s disease (11)
- Primary care (11)
- Seizure (11)
- child (11)
- cognition (11)
- colorectal cancer (11)
- epigenetics (11)
- gene therapy (11)
- integrins (11)
- invasion (11)
- macrophage polarization (11)
- outcome (11)
- oxidative stress (11)
- prevalence (11)
- psoriasis (11)
- radiotherapy (11)
- surgery (11)
- ACLF (10)
- COPD (10)
- Diagnostic markers (10)
- Epidemiology (10)
- Heart failure (10)
- Hepatocellular carcinoma (10)
- Research article (10)
- Small bowel (10)
- Suicide (10)
- Survival (10)
- Trauma (10)
- cell death (10)
- coronavirus (10)
- extracellular matrix (10)
- hepatitis C virus (10)
- infection (10)
- leukemia (10)
- liver (10)
- metastasis (10)
- migration (10)
- neuroblastoma (10)
- osteoarthritis (10)
- proteomics (10)
- risk factors (10)
- Atrial fibrillation (9)
- Autophagy (9)
- Bipolar disorder (9)
- Blood (9)
- Children (9)
- Diagnosis (9)
- Evaluation (9)
- General practice (9)
- HCV (9)
- Hemorrhage (9)
- Kongress (9)
- Macrophages (9)
- Medizinische Ausbildung (9)
- Metastasen (9)
- Pain (9)
- Prostate cancer (9)
- Proteomics (9)
- Schizophrenia (9)
- VEGF (9)
- artificial intelligence (9)
- atherosclerosis (9)
- brain metastases (9)
- complications (9)
- elderly (9)
- hepatocellular carcinoma (9)
- human (9)
- innate immunity (9)
- machine learning (9)
- magnetic resonance imaging (9)
- metabolism (9)
- neurodegeneration (9)
- portal hypertension (9)
- sphingosine-1-phosphate (9)
- vaccination (9)
- Acute myeloid leukemia (8)
- Behandlung (8)
- Cardiovascular magnetic resonance (8)
- Diabetes mellitus (8)
- Diagnostics (8)
- Drug therapy (8)
- Epilepsie (8)
- Europe (8)
- Hepatitis C (8)
- Hepatitis C virus (8)
- Hypertension (8)
- Liver diseases (8)
- Malaria (8)
- Molecular biology (8)
- Multimorbidity (8)
- NASH (8)
- Prognosis (8)
- Rare diseases (8)
- TAVI (8)
- adhesion (8)
- aortic stenosis (8)
- chronic kidney disease (8)
- curcumin (8)
- development (8)
- differentiation (8)
- drug resistance (8)
- medical education (8)
- metastases (8)
- monocytes (8)
- p53 (8)
- periodontitis (8)
- physical activity (8)
- polytrauma (8)
- primary care (8)
- sepsis (8)
- therapy (8)
- trauma (8)
- ubiquitin (8)
- working memory (8)
- AML (7)
- Allgemeinmedizin (7)
- Autism spectrum disorder (7)
- Autopsy (7)
- Brustkrebs (7)
- Cell biology (7)
- DNA methylation (7)
- EGFR (7)
- Endothelial cells (7)
- Gender (7)
- HCC (7)
- HDAC (7)
- Herb induced liver injury (7)
- Hypoxia (7)
- Immunohistochemistry (7)
- Immunological methods (7)
- Immunologische Methoden (7)
- Medical research (7)
- Mental health and psychiatry (7)
- Multiple sclerosis (7)
- NK cells (7)
- Obesity (7)
- Osteoporosis (7)
- PD-L1 (7)
- PI3K (7)
- Patients (7)
- Postural control (7)
- Prevalence (7)
- Prevention (7)
- TRAIL (7)
- Transfusion (7)
- Translational research (7)
- antiviral therapy (7)
- asthma (7)
- biomarkers (7)
- bipolar disorder (7)
- cochlear implant (7)
- efficacy (7)
- fibrosis (7)
- gender (7)
- gene expression (7)
- heart failure (7)
- hematopoietic stem cell transplantation (7)
- hereditary angioedema (7)
- hippocampus (7)
- iron (7)
- liver cirrhosis (7)
- liver transplantation (7)
- machine-learning (7)
- medical students (7)
- microbiome (7)
- mouse (7)
- natural killer cells (7)
- neuropathic pain (7)
- particulate matter (7)
- polypharmacy (7)
- prognosis (7)
- renal cell carcinoma (7)
- resistance (7)
- seizure (7)
- sphingolipids (7)
- thrombosis (7)
- toxicity (7)
- ATM (6)
- Adenocarcinoma (6)
- Antiviral therapy (6)
- Atherosclerosis (6)
- Balloon enteroscopy (6)
- Borrelia (6)
- CDK4/6 (6)
- Cancer treatment (6)
- Clinical trial (6)
- Colorectal cancer (6)
- Comorbidity (6)
- Complications (6)
- Crohn’s disease (6)
- DMEK (6)
- Data science (6)
- Death rates (6)
- Elderly (6)
- Enteroscopy (6)
- Exercise (6)
- Forensic entomology (6)
- Gesundheitspolitik (6)
- Gesundheitswesen (6)
- Glioblastoma (6)
- Goethe-Universität Frankfurt am Main. Fachbereich Humanmedizin (6)
- HBV (6)
- Health economics (6)
- Histology (6)
- Immunsuppression (6)
- In vitro (6)
- Incidence (6)
- Liver transplantation (6)
- Medical education (6)
- Medizin und Gesundheit (6)
- Medizinstudium (6)
- Morbidity (6)
- Multivariate analysis (6)
- Neurology (6)
- Non-small cell lung cancer (6)
- OSCE (6)
- Oral anticoagulation (6)
- Outcomes (6)
- PD1/PDL1 (6)
- Patient blood management (6)
- Physical activity (6)
- Pneumonia (6)
- Polytrauma (6)
- Portal hypertension (6)
- Pregnancy (6)
- Radiomics (6)
- Reactive oxygen species (6)
- Rectal cancer (6)
- Registry (6)
- Rheumatoid arthritis (6)
- Risk factors (6)
- Status epilepticus (6)
- Studien (6)
- Surgical and invasive medical procedures (6)
- T cell (6)
- T cells (6)
- Targeted therapy (6)
- Therapie (6)
- Ultrasound (6)
- Viral load (6)
- acute myeloid leukemia (6)
- acute-on-chronic liver failure (6)
- adolescents (6)
- anemia (6)
- atrial fibrillation (6)
- bevacizumab (6)
- clinical trial (6)
- colon cancer (6)
- cytotoxicity (6)
- dentate gyrus (6)
- diabetes (6)
- diffusion tensor imaging (6)
- environmental tobacco smoke (6)
- exercise (6)
- exosomes (6)
- fibroblasts (6)
- flow cytometry (6)
- growth (6)
- guideline (6)
- immunity (6)
- immunohistochemistry (6)
- influenza (6)
- information theory (6)
- integrin (6)
- iron deficiency (6)
- medizinische Ausbildung (6)
- melanoma (6)
- mesenchymal stromal/stem cells (6)
- microglia (6)
- multimorbidity (6)
- ovarian cancer (6)
- overall survival (6)
- phosphorylation (6)
- platelets (6)
- pregnancy (6)
- prophylaxis (6)
- radiation (6)
- safety (6)
- signal transduction (6)
- sphingosine 1-phosphate (6)
- stress (6)
- systematic review (6)
- tumor-associated macrophages (6)
- vitamin D (6)
- ARDS (5)
- Aging (5)
- Anticoagulation (5)
- Aortic stenosis (5)
- Arteriosklerose (5)
- Artificial intelligence (5)
- Aspergillus (5)
- Ataxia telangiectasia (5)
- Attention (5)
- Attitude (5)
- Autism (5)
- B cells (5)
- BMC (5)
- Biochemistry (5)
- C-reactive protein (5)
- Calliphoridae (5)
- Candida (5)
- Cardiovascular diseases (5)
- Cell signalling (5)
- Clinical trials (5)
- Cognition (5)
- Consensus (5)
- Cytokines (5)
- DAA (5)
- Diabetes (5)
- Diagnose (5)
- Dopamine (5)
- Drug induced liver injury (5)
- ELISA (5)
- Education (5)
- Endothelium (5)
- Epigenetics (5)
- Everolimus (5)
- Ewing sarcoma (5)
- Experimental models of disease (5)
- Gastric cancer (5)
- Gene regulation (5)
- Glioma (5)
- Guidelines (5)
- HIV-1 (5)
- HNSCC (5)
- Heart (5)
- Hepatitis (5)
- Hepatotoxicity (5)
- Herbal hepatotoxicity (5)
- Hippocampus (5)
- Hodgkin lymphoma (5)
- IL-6 (5)
- Kardiovaskuläre Krankheit (5)
- Kommunikation (5)
- MEG (5)
- MRSA (5)
- MRT (5)
- Machine-learning (5)
- Melanoma (5)
- MicroRNAs (5)
- Molecular neuroscience (5)
- Mouse models (5)
- Musculoskeletal system (5)
- NF-κB (5)
- NK cell (5)
- NK-92 (5)
- NKG2D (5)
- NMR-Tomographie (5)
- Omicron (5)
- Pandemic (5)
- Parkinson's disease (5)
- Personalized medicine (5)
- Platelet-rich fibrin (5)
- Polypharmacy (5)
- Predictive markers (5)
- Proliferation (5)
- Psychiatric disorders (5)
- RUCAM (5)
- Randomized controlled trial (5)
- Rhabdomyosarcoma (5)
- Safety (5)
- Signaling (5)
- Smac (5)
- Surgical oncology (5)
- Training (5)
- Treatment outcome (5)
- Tumor microenvironment (5)
- Ubiquitination (5)
- Vaccination (5)
- Validation (5)
- Vitamin D (5)
- XIAP (5)
- acute coronary syndrome (5)
- acute lymphoblastic leukemia (5)
- adaptation (5)
- ataxia telangiectasia (5)
- cardiac surgery (5)
- cell therapy (5)
- ceramides (5)
- cervical cancer (5)
- chimeric antigen receptor (5)
- complement (5)
- conduct disorder (5)
- critical care (5)
- dendritic cells (5)
- dental implants (5)
- diabetes mellitus (5)
- digital medicine (5)
- evaluation (5)
- everolimus (5)
- forensic entomology (5)
- functional magnetic resonance imaging (5)
- graph theory (5)
- hyperglycemia (5)
- lipocalin-2 (5)
- liver fibrosis (5)
- lncRNA (5)
- meningioma (5)
- metabolomics (5)
- mice (5)
- mutual information (5)
- natural killer cell (5)
- nitric oxide (5)
- outcomes (5)
- pandemic (5)
- patient blood management (5)
- patients (5)
- plasticity (5)
- precision medicine (5)
- predictive coding (5)
- preeclampsia (5)
- prostaglandins (5)
- public health (5)
- qualitative research (5)
- quantitative MRI (5)
- regeneration (5)
- rhabdomyosarcoma (5)
- rheumatoid arthritis (5)
- screening (5)
- sulforaphane (5)
- synaptic plasticity (5)
- transcranial magnetic stimulation (5)
- ubiquitination (5)
- vaccine (5)
- valproic acid (5)
- vector (5)
- 177Lu-PSMA-617 (4)
- 3D printing (4)
- ABCB1 (4)
- Acute inflammation (4)
- Acute lymphoblastic leukemia (4)
- Adhesion (4)
- Age groups (4)
- Alcohol (4)
- Alzheimer's disease (4)
- Alzheimer’s disease (4)
- Anemia (4)
- Angiography (4)
- Animal models (4)
- Antikörper (4)
- Aortic valve (4)
- Ascites (4)
- Aspergillus fumigatus (4)
- Bacterial infection (4)
- Biopsy (4)
- Bladder cancer (4)
- Blood pressure (4)
- Bone marrow (4)
- Brain (4)
- Brain metastasis (4)
- CIK cells (4)
- CRISPR/Cas9 (4)
- CRP (4)
- CT (4)
- CXCR4 (4)
- Cannabis (4)
- Cardiology (4)
- Cardiovascular disease (4)
- Cell proliferation (4)
- Cell staining (4)
- Cell therapy (4)
- Cesarean section (4)
- Chemoradiotherapy (4)
- Chronic kidney disease (4)
- Classification (4)
- Clinical genetics (4)
- Cohort studies (4)
- Communication (4)
- Critical care (4)
- DILI (4)
- DNA damage (4)
- DTI (4)
- Data processing (4)
- Decision making (4)
- Decorin (4)
- Denosumab (4)
- Density equalizing mapping (4)
- Developmental biology (4)
- Diagnostic medicine (4)
- Dravet syndrome (4)
- E-Learning (4)
- ER stress (4)
- Emotion regulation (4)
- Emotions (4)
- Endoscopic retrograde cholangiopancreatography (4)
- Epileptischer Anfall (4)
- Evidence-based medicine (4)
- Extracellular matrix (4)
- Extracellular vesicles (4)
- Fibrosis (4)
- Flow cytometry (4)
- Genetics research (4)
- Geschlecht (4)
- Gesundheitsökonomie (4)
- Glioblastom (4)
- HAE (4)
- Health care (4)
- Healthcare worker (4)
- Heart transplantation (4)
- Hematology (4)
- Hereditary angioedema (4)
- Hirnforschung (4)
- Homeostasis (4)
- IAP proteins (4)
- Immunologie (4)
- Immunsystem (4)
- Infection (4)
- Infections (4)
- Innate immunity (4)
- IntelliCage (4)
- Intensive care (4)
- Intensive care units (4)
- Interleukin (4)
- Interleukin-6 (4)
- Kinematic analysis (4)
- Knees (4)
- Labor and delivery (4)
- Lebensqualität (4)
- Legs (4)
- Liver cirrhosis (4)
- Liver fibrosis (4)
- Long non-coding RNAs (4)
- Lung failure (4)
- Lymphozyt (4)
- MSD (4)
- Mechanisms of disease (4)
- Medical risk factors (4)
- Medizindidaktik (4)
- Medizinstudenten (4)
- Medizinstudierende (4)
- Migration (4)
- Molecular medicine (4)
- Mouse (4)
- Musculoskeletal diseases (4)
- Myocardial infarction (4)
- NAFLD (4)
- NO (4)
- Neonates (4)
- Neutropenia (4)
- Next-generation sequencing (4)
- Nierentransplantation (4)
- Nox4 (4)
- NoxO1 (4)
- Nrf2 (4)
- PSMA (4)
- Pandemie (4)
- Patient safety (4)
- Pediatric (4)
- Physicians (4)
- Physiology (4)
- Prophylaxis (4)
- Prostatakarzinom (4)
- Psychology (4)
- Pulmonary embolism (4)
- Quality of care (4)
- Quantitative MRI (4)
- Register (4)
- Registries (4)
- Rehabilitation (4)
- Resistenz (4)
- Risiko (4)
- Roussel Uclaf Causality Assessment Method (4)
- STAT3 (4)
- Schlaganfall (4)
- Schmerz (4)
- Screening (4)
- Seltene Erkrankungen (4)
- Sensitivity (4)
- Sensitivity and Specificity (4)
- Sex (4)
- Sex differences (4)
- Sport (4)
- Stem cell (4)
- Stem cells (4)
- Surveillance (4)
- Systematic review (4)
- TACE (4)
- Tacrolimus (4)
- Therapy (4)
- Thrombose (4)
- Thrombosis (4)
- Tissue engineering (4)
- Tumormarker (4)
- Ultraschall (4)
- Wound healing (4)
- acetaminophen (4)
- acute kidney injury (4)
- adjuvant therapy (4)
- adjuvante Therapie (4)
- adverse events (4)
- age (4)
- aggression (4)
- alcohol (4)
- alirocumab (4)
- anaemia (4)
- animal model (4)
- antibodies (4)
- antioxidants (4)
- augmentation (4)
- bibliometrics (4)
- bibliometry (4)
- bioinformatics (4)
- brachytherapy (4)
- cGMP (4)
- cancer stem cells (4)
- cardiovascular disease (4)
- cell biology (4)
- cell migration (4)
- cerebrospinal fluid (4)
- chemoradiotherapy (4)
- chemoresistance (4)
- cholesterol (4)
- classification (4)
- climate change (4)
- clinical study (4)
- combination therapy (4)
- complication (4)
- computed tomography (4)
- cortex (4)
- cystic fibrosis (4)
- cytomegalovirus (4)
- dementia (4)
- dental implant (4)
- dentist (4)
- direct-acting antivirals (4)
- doxorubicin (4)
- early breast cancer (4)
- electroencephalography (4)
- electrolytic cleaning (4)
- entropy (4)
- ergonomics (4)
- extracellular vesicles (4)
- faculty development (4)
- frühes Mammakarzinom (4)
- general practice (4)
- haemophilia treatment (4)
- health-related quality of life (4)
- heart (4)
- hemorrhage (4)
- hepatitis C (4)
- hepatitis C virus (HCV) (4)
- histology (4)
- imaging (4)
- immune evasion (4)
- immune response (4)
- impulsivity (4)
- in vitro (4)
- inflammasome (4)
- inflammatory bowel disease (4)
- kidney (4)
- leukocytes (4)
- levetiracetam (4)
- lipoxygenase (4)
- long non-coding RNA (4)
- mTORC1 (4)
- management (4)
- mass spectrometry (4)
- mesenchymal stromal cells (4)
- metabolic syndrome (4)
- metastatic prostate cancer (4)
- motility (4)
- multiple myeloma (4)
- musculoskeletal disorders (4)
- neoadjuvant therapy (4)
- neural oscillations (4)
- nociception (4)
- p21 (4)
- pancreatic cancer (4)
- patient safety (4)
- pediatric (4)
- perception (4)
- periimplantitis (4)
- peripheral artery disease (4)
- phagocytosis (4)
- primary cilium (4)
- primary health care (4)
- primary immunodeficiency (4)
- proteome (4)
- psoriatic arthritis (4)
- questionnaire (4)
- rapamycin (4)
- rat (4)
- registry (4)
- risk (4)
- simulation training (4)
- smoking (4)
- spirochetes (4)
- status epilepticus (4)
- stem cell transplantation (4)
- temozolomide (4)
- temporal lobe epilepsy (4)
- thrombolysis (4)
- thymus (4)
- tissue engineering (4)
- tooth loss (4)
- transfusion (4)
- transplantation (4)
- traumatic brain injury (4)
- treatment centres (4)
- trials (4)
- tumor growth (4)
- tumor progression (4)
- wound healing (4)
- (surface) partial differential equations (3)
- 3D rapid prototyping (3)
- ADAM15 (3)
- ALL (3)
- Abdominal aortic aneurysm (3)
- Acute kidney injury (3)
- Adherence (3)
- Adults (3)
- Adverse events (3)
- Allergie (3)
- Amblyopia (3)
- Antibiotics (3)
- Antibodies (3)
- Antiretroviral therapy (3)
- Anämie (3)
- Aortic valve replacement (3)
- Arbeitsgedächtnis (3)
- Ataxia-telangiectasia (3)
- Autismus (3)
- B-cell lymphoma (3)
- BAG3 (3)
- BCR/ABL (3)
- BMI (3)
- BRAF (3)
- BRD4 (3)
- Behavior (3)
- Bibliometrics (3)
- Biographie (3)
- Blood-brain barrier (3)
- Bone defect (3)
- Bone regeneration (3)
- Bone tissue engineering (3)
- Borrelia burgdorferi (3)
- Brain tumor (3)
- Bronchialasthma (3)
- Burden of illness (3)
- C. elegans (3)
- C1 inhibitor (3)
- CAD/CAM (3)
- CAR (3)
- CD36 (3)
- COMP (3)
- CRM (3)
- CTGF (3)
- CXCL12 (3)
- CXCR3 (3)
- Calcium (3)
- Cancer chemotherapy (3)
- Cancer detection and diagnosis (3)
- Cancer genetics (3)
- Cancer genomics (3)
- Cardiac surgery (3)
- Carotis (3)
- Case report (3)
- Catheter ablation (3)
- Cerebellum (3)
- Cerebrospinal fluid (3)
- Chaperone (3)
- Child (3)
- Chromatin accessibility (3)
- Chronic diseases (3)
- Chronic hepatitis C (3)
- Ciclosporin (3)
- Citation analysis (3)
- Clinical Trials and Observations (3)
- Clinical competence (3)
- Clinical decision support systems (3)
- Cochlear implant (3)
- Cochlear implantation (3)
- Cognitive impairment (3)
- Cognitive neuroscience (3)
- Collagen (3)
- Comorbidities (3)
- Complex I (3)
- Compliance (3)
- Computer software (3)
- Computer-assisted diagnosis (3)
- Conduct disorder (3)
- Connective tissue (3)
- Corona (3)
- Coronary heart disease (3)
- Costs (3)
- Cystic fibrosis (3)
- Cytoskeleton (3)
- DNA mismatch repair (3)
- DNase1-seq (3)
- Deep brain stimulation (3)
- Delegation (3)
- Dental implant (3)
- Dental students (3)
- Dentistry (3)
- Digitalisierung (3)
- Dose response (3)
- Drug hepatotoxicity (3)
- Drug resistance (3)
- Drugs (3)
- ECMO (3)
- EEG microstates (3)
- Eccentric fixation (3)
- Edema (3)
- Efficiency (3)
- Ejection fraction (3)
- Electroencephalography (3)
- Emergency room (3)
- Encephalopathy (3)
- Endocrinology (3)
- Endovascular repair (3)
- Entscheidungsassistenz (3)
- Entzündung (3)
- Epileptische Anfälle (3)
- European Union (3)
- Europäische Union (3)
- Exosomes (3)
- Eyes (3)
- FFLU (3)
- FTY720 (3)
- Fasting (3)
- Feedback (3)
- Fibronectin (3)
- Fingolimod (3)
- Finite Volumes (3)
- Fistula (3)
- Forensic medicine (3)
- Frühgeburt (3)
- Functional clustering (3)
- G-CSF (3)
- GPCR (3)
- Gene Regulation (3)
- Gene fusion (3)
- Gene therapy (3)
- Genome-wide association studies (3)
- Global health (3)
- Glucose (3)
- H1N1 (3)
- HER2 (3)
- HER2/neu (3)
- HIF (3)
- HPV (3)
- HSCT (3)
- Head and neck cancer (3)
- Health services research (3)
- Healthcare costs (3)
- Healthy adults (3)
- HepG2 (3)
- Hepatitis B (3)
- HoLEP (3)
- Hospitals (3)
- Human genetics (3)
- Hämodynamik (3)
- IAPs (3)
- IBD (3)
- ICD (3)
- IFT (3)
- IL-1β (3)
- Immunchemie (3)
- Immunosuppression (3)
- Induction chemotherapy (3)
- Inflammatory bowel disease (3)
- Inflammatory diseases (3)
- Influenza (3)
- Insulin (3)
- Integrin (3)
- Interleukin-22 (3)
- Ischemia (3)
- Jaw (3)
- Kidney transplantation (3)
- Kinder (3)
- Knochenersatzmaterial (3)
- Knowledge (3)
- Kolonkarzinom (3)
- LCMV (3)
- LPS (3)
- Langerhans cell histiocytosis (3)
- Language (3)
- Leberzirrhose (3)
- Lehre (3)
- Lehrqualifikation (3)
- Lesions (3)
- Leukozyt (3)
- Liver Transplantation (3)
- LncRNA (3)
- Lumbar spine (3)
- MCAK (3)
- MLL (3)
- MYC (3)
- Macrophage polarization (3)
- Major depressive disorder (3)
- Masquelet technique (3)
- Mass spectrometry (3)
- Medizingeschichte (3)
- Medizinische Versorgung (3)
- Memory (3)
- Mental health (3)
- Mesenchymal stem cells (3)
- Messenger RNA (3)
- Metabolic diseases (3)
- Metabolomics (3)
- Methicillin-resistant Staphylococcus aureus (3)
- Microbiology (3)
- Microbiome (3)
- Microwave ablation (3)
- Mitochondrial dysfunction (3)
- Mitosis (3)
- Morphogenesis (3)
- Motor control (3)
- Multianalyte detection (3)
- Multidetector computed tomography (3)
- Multiplate (3)
- Musculoskeletal disorder (3)
- NADH dehydrogenase (3)
- NSCLC (3)
- Neuroblastom (3)
- Neurochirurgie (3)
- Neurodegeneration (3)
- Neuroinflammation (3)
- Nitric oxide (3)
- Nivolumab (3)
- Non-coding RNA (3)
- Nox (3)
- OSPE (3)
- OXA-48 (3)
- Obduktion (3)
- Observational study (3)
- Occlusion treatment (3)
- Occupational health (3)
- Offene Versorgung (3)
- Open repair (3)
- Oxidativer Stress (3)
- PARK2 (3)
- PDGFRβ (3)
- PSA (3)
- Pathogenesis (3)
- Pediatric patients (3)
- Pediatrics (3)
- Penile carcinomas (3)
- Peri-implantitis (3)
- Periodontitis (3)
- Phagocytosis (3)
- Phosphorylation (3)
- Platelets (3)
- Podospora anserina (3)
- Portal veins (3)
- Pre-analytics (3)
- Preclinical research (3)
- Prediction (3)
- Preterm birth (3)
- Preventive medicine (3)
- Primary health care (3)
- Primärversorgung (3)
- Prognostic markers (3)
- Progranulin (3)
- Protease inhibitor therapy (3)
- Psoriasis (3)
- Public health (3)
- Pulmonary hypertension (3)
- Qualitätssicherung (3)
- RCT (3)
- RITA (3)
- RNA (3)
- RNA therapeutics (3)
- Reaction time (3)
- Rechtsmedizin (3)
- Regeneration (3)
- Regression analysis (3)
- Reliabilität (3)
- Renal cell carcinoma (3)
- Research Article (3)
- Respiration (3)
- Rezidiv (3)
- S1P (3)
- SUDEP (3)
- SUMO (3)
- SVR (3)
- Sarcoma (3)
- Schwangerschaft (3)
- Senescence (3)
- Sensitivität und Spezifität (3)
- Serodiagnosis (3)
- Simulated patients (3)
- Sleep (3)
- Sports and exercise medicine (3)
- Squamous cell carcinoma (3)
- Statistical data (3)
- Stereotactic body radiation therapy (3)
- Sudden cardiac death (3)
- Suicidality (3)
- Surgeons (3)
- TGF-β (3)
- TIPS (3)
- TKI (3)
- TSC (3)
- Teaching (3)
- Tele-EEG (3)
- Telemedicine (3)
- Temozolomide (3)
- Thoracic trauma (3)
- Thrombozytenkonzentrat (3)
- Thyroid (3)
- Todesart (3)
- Torque (3)
- Toxicity (3)
- Transarterial chemoembolization (3)
- Transcription factors (3)
- Type 2 diabetes (3)
- Undergraduate medical education (3)
- Upper body posture (3)
- Variant histology (3)
- Versorgungsqualität (3)
- Wundheilung (3)
- Zika virus (3)
- Zoonosis (3)
- accident (3)
- acute coronary syndromes (3)
- acute decompensation (3)
- adenosine (3)
- adherence (3)
- adult (3)
- aged (3)
- ageing (3)
- albumin (3)
- alcohol use disorder (3)
- allogeneic stem cell transplantation (3)
- alveolar ridge augmentation (3)
- anal cancer (3)
- animal (3)
- animal models (3)
- anti-angiogenic therapy (3)
- antiviral (3)
- arteriogenesis (3)
- ascites (3)
- aspirin (3)
- astrocytes (3)
- atezolizumab (3)
- auditory cortex (3)
- autism spectrum disorder (3)
- bacteria (3)
- behavior (3)
- biocompatibility (3)
- bioenergetics (3)
- bleeding (3)
- blood (3)
- blood transfusion (3)
- body mass index (3)
- bone (3)
- bone regeneration (3)
- bortezomib (3)
- brain imaging (3)
- brain metastasis (3)
- breast (3)
- burden of illness (3)
- cAMP (3)
- calprotectin (3)
- calretinin (3)
- cancer immunotherapy (3)
- carbapenemases (3)
- cardiac (3)
- caregivers (3)
- cartilage (3)
- caspase-2 (3)
- caspase-8 (3)
- catheter ablation (3)
- cell cycle (3)
- cerebellum (3)
- chemokines (3)
- chronic myeloid leukemia (3)
- cisplatin (3)
- classical Hodgkin lymphoma (3)
- clinical benefit (3)
- clinical research (3)
- clinical trials (3)
- clock genes (3)
- co-infection (3)
- collagen (3)
- colon (3)
- complexome profiling (3)
- computational virology (3)
- confinement (3)
- connectivity (3)
- cortisol (3)
- critical size defect (3)
- critically ill patients (3)
- cytokine-induced killer cells (3)
- dental education (3)
- dental profession (3)
- dexamethasone (3)
- diabetic nephropathy (3)
- diagnostic algorithm (3)
- diagnostics (3)
- didactic (3)
- dopamine (3)
- drug discovery (3)
- drug induced liver injury (3)
- eNOS (3)
- echocardiography (3)
- education (3)
- electrophysiology (3)
- endocannabinoids (3)
- endoplasmic reticulum (3)
- epidermal growth factor receptor (3)
- event-related potentials (3)
- executive function (3)
- external beam radiotherapy (3)
- fatigue (3)
- fenfluramine (3)
- focal adhesion (3)
- follow-up (3)
- functional connectivity (3)
- functional outcome (3)
- gamma (3)
- gastric cancer (3)
- gene regulation (3)
- genetics (3)
- glycolysis (3)
- growth inhibition (3)
- guidelines (3)
- haemophilia care (3)
- head and neck cancer (3)
- healthcare worker (3)
- heart rate (3)
- hematopoietic stem and progenitor cells (3)
- hemodialysis (3)
- hepatitis B (3)
- herb induced liver injury (3)
- histone acetylation (3)
- hyperactivity (3)
- immune cells (3)
- immune checkpoint inhibitors (3)
- immune escape (3)
- immune reconstitution (3)
- immunology (3)
- immunosuppression (3)
- inertial motion capture (3)
- insulin resistance (3)
- interleukin-22 (3)
- interleukins (3)
- invasive fungal disease (3)
- invasive fungal infection (3)
- iron metabolism (3)
- irradiation (3)
- language (3)
- leptin (3)
- lipids (3)
- liver injury (3)
- local recurrence (3)
- lockdown (3)
- lung function (3)
- lyme disease (3)
- lymphoma (3)
- mRNA (3)
- magnetoencephalography (3)
- massively parallel multigrid solvers (3)
- mathematical modeling (3)
- memory (3)
- metastatic (3)
- metformin (3)
- miRNAs (3)
- microwave ablation (3)
- mild cognitive impairment (3)
- mitochondrial disease (3)
- mitophagy (3)
- mitosis (3)
- modeling (3)
- molecular mechanisms (3)
- monitoring (3)
- monoclonal antibody (3)
- morbidity (3)
- mouse model (3)
- multidrug resistance (3)
- mycophenolic acid (3)
- myocarditis (3)
- necroptosis (3)
- neoadjuvant chemotherapy (3)
- neonate (3)
- neoplasms (3)
- neural network (3)
- neurocritical care (3)
- neuroimaging (3)
- neuropathy (3)
- neutralization (3)
- neutralizing antibodies (3)
- newborn (3)
- next-generation sequencing (3)
- non-coding RNA (3)
- observational study (3)
- occupational infections (3)
- oncology (3)
- online survey (3)
- osteoporosis (3)
- overweight (3)
- oxidative phosphorylation (3)
- p47phox (3)
- pediatric patients (3)
- pentose phosphate pathway (3)
- perforant path transection (3)
- perfusion (3)
- peri-implantitis (3)
- pericarditis (3)
- pharmacodynamics (3)
- plasmid (3)
- platelet-rich fibrin (3)
- pneumonia (3)
- predictor (3)
- prefrontal cortex (3)
- primary prostate cancer (3)
- prognostic factors (3)
- prostaglandin (3)
- proteoglycan (3)
- quality assurance (3)
- radical prostatecomy (3)
- realistic geometries (3)
- receptor (3)
- reliability (3)
- remodelling (3)
- renal cell cancer (3)
- renal function (3)
- reproducibility (3)
- resting state (3)
- review (3)
- rituximab (3)
- salvage therapy (3)
- seizures (3)
- senescence (3)
- serum (3)
- severe acute respiratory syndrome coronavirus 2 (3)
- sex (3)
- signaling (3)
- simulation (3)
- skeletal muscle (3)
- sleep (3)
- soft tissue sarcoma (3)
- sphingolipid (3)
- spinal cord (3)
- strength training (3)
- stress response (3)
- supportive periodontal therapy (3)
- surgical procedures (3)
- systematic biopsy (3)
- systemic antibiotics (3)
- therapeutics (3)
- therapy monitoring (3)
- tobacco prevention (3)
- toll-like receptor (3)
- training (3)
- transcription factor (3)
- transcriptome (3)
- transient elastography (3)
- tyrosine kinase inhibitor (3)
- tyrosine kinase inhibitors (3)
- ultrasound (3)
- vemurafenib (3)
- viral dynamics (3)
- working conditions (3)
- yeast (3)
- zinc (3)
- - (2)
- 3D spatio-temporal resolved mathematical models (2)
- 5-lipoxygenase (2)
- A/D transition (2)
- ABCC1 (2)
- ABCG2 (2)
- ACL (2)
- ADHS (2)
- AIDS (2)
- AKI (2)
- ALK (2)
- AMH (2)
- AMPK (2)
- ARFI (2)
- ATP (2)
- ATP-citrate lyase (2)
- Abdominelles Aortenaneurysma (2)
- Abort (2)
- Academic medicine (2)
- Access (2)
- Accidental reaction (2)
- Acinetobacter baumannii (2)
- Acne inversa (2)
- Acoustics (2)
- Activities of daily living (2)
- Acuris (2)
- Acute Myeloid Leukemia (AML) (2)
- Acute decompensation (2)
- Acute lymphocytic leukaemia (2)
- Acute myeloid leukaemia (2)
- Acute seizure plan (2)
- Acute-on-chronic liver failure (2)
- Addiction (2)
- Addison’s disease (2)
- Adipose tissue (2)
- Adipose-derived mesenchymal stem cells (2)
- Adolescents (2)
- Adult neurogenesis (2)
- Adverse drug reaction (2)
- Aedes aegypti (2)
- Aedes albopictus (2)
- Affinity Labeling (2)
- Age estimation (2)
- Akaike information criterion (AIC) (2)
- Akute lymphatische Leukämie (2)
- Akuter Anfallsplan (2)
- Alcohol consumption (2)
- Alcoholic liver disease (2)
- Algorithms (2)
- Alleles (2)
- Allergen avoidance (2)
- Allergic asthma (2)
- Allergy (2)
- Allosteric inhibition (2)
- Alpelisib (2)
- Alzheimer (2)
- Anaemia (2)
- Anal cancer (2)
- Analgesia (2)
- Analgesie (2)
- Anandamide (2)
- Anatomy (2)
- Angiographie (2)
- Animal model (2)
- Anschlussheilbehandlung (2)
- Anti-IgE (2)
- Anti-seizure medication (2)
- Anticoagulant therapy (2)
- Anticonvulsants (2)
- Antigen test (2)
- Antikonvulsiva (2)
- Antikörpertest (2)
- Antimicrobial treatment (2)
- Antiretrovirals (2)
- Anxiety (2)
- Aortic dissection (2)
- Apheresis (2)
- Apixaban (2)
- Arrhythmia (2)
- Arthroplasty (2)
- Arzneimittelmarkt (2)
- Arzneimittelrecht (2)
- Asphyxia (2)
- Assessment (2)
- Asthma (2)
- Ataxia (2)
- Atezolizumab (2)
- Attention-deficit/hyperactivity disorder (2)
- Auditory rehabilitation (2)
- Auditory system (2)
- Aurora A (2)
- Austria (2)
- Autoimmunity (2)
- Autologous biomaterial (2)
- BA.1 (2)
- BCL2 (2)
- BCL6 (2)
- BCOR (2)
- BCX7353 (2)
- BDNF (2)
- BMNC (2)
- BNT162b2 (2)
- BPH (2)
- BRCA1 (2)
- BRCA2 (2)
- Babesia divergens (2)
- Babesia microti (2)
- Back pain (2)
- Bartonella henselae (2)
- Bauchaortenaneurysma (2)
- Behandlungsposition (2)
- Benefit (2)
- Berufskrankheit (2)
- Betriebliche Gesundheitsförderung (2)
- Bevacizumab (2)
- Big Data (2)
- Big Five (2)
- Biglycan (2)
- Bile duct stone (2)
- Biofilm (2)
- Bioinformatics (2)
- Biological profile (2)
- Biomedical informatics (2)
- Biophysical models (2)
- Biorecognition strategies (2)
- Biosynthetic mesh (2)
- Bipolar (2)
- Birth weight (2)
- Bleeding (2)
- Blog (2)
- Blood groups (2)
- Blood loss (2)
- Blood loss estimation (2)
- Blood plasma (2)
- Bloodstream infections (2)
- Blow flies (2)
- Blutübertragbare Virusinfektionen (2)
- Body mass index (2)
- Body modification (2)
- Body posture (2)
- Bone density (2)
- Bone marrow aspiration (2)
- Bone marrow-derived mesenchymal stem cells (2)
- Bone metastases (2)
- Bowel obstruction (2)
- Brasilien (2)
- Breast neoplasms (2)
- Breast tumors (2)
- Burden of disease (2)
- CAM (2)
- CBA (2)
- CC16 (2)
- CCL2 (2)
- CD14 (2)
- CD16 (2)
- CD19 (2)
- CD44 (2)
- CD62 (2)
- CDK9 (2)
- CDKN1A (2)
- CIOMS (2)
- CIRS (2)
- CLP (2)
- CMV (2)
- COVID 19 (2)
- COVID-19 surveillance (2)
- CPE (2)
- CRISPR/Cas (2)
- CSM (2)
- CTLA-4 (2)
- CUELA (2)
- CV9202 (2)
- Callous-unemotional traits (2)
- Calpain (2)
- Calprotectin (2)
- Cancer epidemiology (2)
- Cancer models (2)
- Cancer therapy (2)
- Cancer-specific mortality (2)
- Cannabidiol (2)
- Capecitabine (2)
- Carbapenemase (2)
- Cardiac arrest (2)
- Cardiac hypertrophy (2)
- Cardiac magnetic resonance (2)
- Cardioprotection (2)
- Cardiovascular biology (2)
- Carotisstenose (2)
- Case management (2)
- Cats (2)
- Causality assessment (2)
- Celiac disease (2)
- Cell binding (2)
- Cell culture (2)
- Cell death (2)
- Cell death and immune response (2)
- Cell differentiation (2)
- Cell division (2)
- Cell salvage (2)
- Checkpoint inhibitor (2)
- Chemical biology (2)
- Chemokines (2)
- Chemoprevention (2)
- Children and adolescents (2)
- Chirurgie (2)
- Cholangiography (2)
- Cholangiopancreatography (2)
- Chondrocytes (2)
- Chronic disease (2)
- Chronic hepatitis (2)
- Chronic inflammation (2)
- Chronic obstructive pulmonary disease (2)
- Chronisch-myeloische Leukämie (2)
- Clinical Global Impression of Change (2)
- Clinical presentation (2)
- Clinical studies (2)
- Clinical study (2)
- Cocaine (2)
- Cochleaimplantation (2)
- Cognitive behavioral therapy (2)
- Colloids (2)
- Colonoscopy (2)
- Community based intervention (2)
- Community health services (2)
- Comparative analysis (2)
- Complex Formation (2)
- Complication management (2)
- Computational models (2)
- Computer hardware (2)
- Computer science (2)
- Computertomographie (2)
- Coronary artery disease (2)
- Coronavirus (2)
- Cortex (2)
- Cost-effectiveness (2)
- Covid-19 (2)
- Croatia (2)
- Crohn's disease (2)
- Cryoelectron microscopy (2)
- Crystal structure (2)
- CspZ (2)
- Cuela (2)
- Curriculum (2)
- CyberKnife robotic radiosurgery (2)
- CysLTR1 (2)
- Cytogenetics (2)
- Cytokine (2)
- Cytologie (2)
- Cytoskeletal proteins (2)
- DMARDs (biologic) (2)
- DNA (2)
- DNA damage response (2)
- DSM (2)
- Daptomycin (2)
- Data visualization (2)
- Decision (2)
- Decision trees (2)
- Defibrillation (2)
- Degradation (2)
- Dehydrogenases (2)
- Dementia (2)
- Dengue (2)
- Density-equalizing mapping (2)
- Dental implants (2)
- Dentist (2)
- Dentists (2)
- Development (2)
- Diagnostic algorithm (2)
- Diagnostic test (2)
- Dialyse (2)
- Differential diagnosis (2)
- Differentiation (2)
- Differenzierung (2)
- Digestive system procedures (2)
- Digitalization (2)
- Direct current electrical stimulation (2)
- Directly acting antiviral agent (2)
- Disease Activity (2)
- Diseases (2)
- Disintegration (2)
- Distance to water (2)
- Docetaxel (2)
- Double-balloon enteroscopy (2)
- Drug development (2)
- Dynamic MRI (2)
- E3 ligase (2)
- EBM (2)
- EEG-fMRI (2)
- EET (2)
- EMT (2)
- ENCODE-DREAM in vivo Transcription Factor binding site prediction challenge (2)
- EQ-5D (2)
- ERP (2)
- ESBL (2)
- EWSR1 (2)
- Ears (2)
- Edinger, Ludwig (2)
- Edoxaban (2)
- Efficacy (2)
- Electrical stimulation (2)
- Electrophysiology (2)
- Elevation (2)
- Empathy (2)
- EndMT (2)
- Endocannabinoid (2)
- Endocannabinoids (2)
- Endokrinologie (2)
- Endoscopic retrograde (2)
- Endoscopic ultrasound (2)
- Endothel (2)
- Endothelial permeability (2)
- Endotoxin (2)
- Endovaskuläre Behandlung (2)
- Ensemble learning (2)
- Enterobacteriaceae (2)
- Enterscopy (2)
- Environmental support (2)
- Enzyme-linked Immunosorbent Assay (2)
- Enzyme-linked immunoassays (2)
- EphB4 (2)
- Epicutaneous immunotherapy (2)
- Epidemiologie (2)
- Epidemiology and End Results (2)
- Epidermal growth factor receptor (2)
- Epileptic seizures (2)
- Epstein-Barr virus (2)
- Equity (2)
- Ergonomics (2)
- Erwachsene (2)
- Erweiterter Suizid (2)
- Etiology (2)
- Europäische Integration (2)
- Euthanasie <Nationalsozialismus> (2)
- Evidence based medicine (2)
- Evidence-based (2)
- Evidence-based dentistry (2)
- Evidenzbasierte Medizin (2)
- Extended donor criteria (2)
- Extended suicide (2)
- Extracellular matrix proteins (2)
- Eye movements (2)
- FEV1 (2)
- FGFR (2)
- FHIR (2)
- FLT3-ITD (2)
- Face (2)
- Family practice (2)
- Fatty liver (2)
- Feasibility (2)
- Fertilität (2)
- Fertilité (2)
- Fibroblasts (2)
- Finanzierung (2)
- Flaps (2)
- Follow-up treatment (2)
- Forensische Osteologie (2)
- Fortbildung (2)
- Frailty (2)
- Früherkennung (2)
- Fuchs endothelial dystrophy (2)
- Function (2)
- Functional characterization (2)
- Functional connectivity (2)
- Functional electrical stimulation (2)
- Functional magnetic resonance imaging (2)
- Funding (2)
- G2A (2)
- GABA (2)
- GEMs (2)
- GFAP (2)
- GWAS (2)
- Gadobutrol (2)
- Gait analysis (2)
- Galaktografie (2)
- Galaktomosynthese (2)
- Gastritis (2)
- Gastrointestinal bleeding (2)
- Gastroschisis (2)
- Gelenkersatz (2)
- Gemeinschaftliche Selbsttötung (2)
- Gender reassigning surgery (2)
- Gene ontology (2)
- General practitioners (2)
- Genetic testing (2)
- Genetik (2)
- Geographic variation (2)
- Geographically weighted regression (GWR) (2)
- Geriatric patients (2)
- Gerinnungsfaktor VIII (2)
- German people (2)
- Geschichte (2)
- Gesetz zur Verhütung erbkranken Nachwuchses (2)
- Gesetzliche Krankenversicherung (2)
- Gesundheit (2)
- Gezielte Therapie (2)
- Glaucoma (2)
- Gleason score (2)
- Glucose metabolism (2)
- Glycolysis (2)
- Goldstein, Kurt (2)
- Grafts (2)
- Growth factors (2)
- Guideline (2)
- HBsAg (2)
- HCMV (2)
- HDACi (2)
- HES (2)
- HIV protease inhibitors (2)
- HIV-Infektion (2)
- HL7 FHIR (2)
- HOD (2)
- HRM (2)
- HSV (2)
- HSV-1 (2)
- Hashimoto-Thyreoiditis (2)
- Hausarztmangel (2)
- Hausarztpraxis (2)
- Health care workers (2)
- Health policy (2)
- Health services (2)
- Healthcare personnel (2)
- Healthcare resource utilization (2)
- Hematologic malignancies (2)
- Hemodynamics (2)
- Hepatitis-C-Virus (2)
- Hepatocytes (2)
- Herpes Zoster Infektion (2)
- Herpes-simplex-Virus (2)
- Herztransplantation (2)
- Heterogeneity (2)
- High oblique sagittal osteotomy (2)
- High-density lipoprotein (2)
- Hirninfarkt (2)
- Histologie (2)
- Holmes tremor (2)
- Homicide (2)
- Homosexualität (2)
- Hospital (2)
- HuR (2)
- Hypertonie (2)
- Hörrehabilitation (2)
- Hörrinde (2)
- Hüfte (2)
- ICU (2)
- IDH mutation (2)
- IHC (2)
- IL-10 (2)
- IL-12 (2)
- IL-33 (2)
- IR-A (2)
- ISR (2)
- Identification (2)
- Ileus (2)
- Image analysis (2)
- Image processing (2)
- Imatinib mesilat (2)
- Immune cells (2)
- Immune suppression (2)
- Immune system (2)
- Immunenzymtechniken (2)
- Immunity (2)
- Immunität <Medizin> (2)
- Immunmodulation (2)
- Immunoenzyme Techniques (2)
- Immunogenicity (2)
- Immunturbidimetrie (2)
- Impfraten (2)
- Impfstoff (2)
- Impfung (2)
- Implementation (2)
- In vivo (2)
- Incidence rate (2)
- Incisional hernia (2)
- Indirect-binding (2)
- Indonesia (2)
- Infection control (2)
- Infectious diseases (2)
- Infektiologie (2)
- Infektion (2)
- Information theory (2)
- Injuries (2)
- Injury (2)
- Innate Immunity (2)
- Insulin signalling (2)
- Integration (2)
- Intensive care treatment (2)
- Interdisciplinarity (2)
- Interferon (2)
- Interleukin-1 (2)
- Internet (2)
- Interview (2)
- Iron (2)
- Iron deficiency (2)
- Iron deficiency anemia (2)
- Ischemia/reperfusion injury (2)
- Ixodes ricinus (2)
- Joint loading (2)
- KGF (2)
- Katherine (2)
- Ketogenic diet (2)
- Ki-67 (2)
- Kinases (2)
- Kind (2)
- Kinderwunsch (2)
- Klassifikation (2)
- Klebsiella pneumoniae (2)
- Klinische Ergebnisse (2)
- Klinische Kompetenz (2)
- Knochen (2)
- Kolorektales Karzinom (2)
- Kommerzialisierung (2)
- Kompetenzen (2)
- Komplikation (2)
- Krankenhaus (2)
- Krankenhausfinanzierung (2)
- Krankenversicherung (2)
- Krebs (2)
- Körperbild (2)
- Körperhaltung (2)
- L-DOPA (2)
- L2 (2)
- LSCC (2)
- LVAD (2)
- Labordiagnostik (2)
- Lactate Dehydrogenase (2)
- Landarztprogramm (2)
- Laparoskopie (2)
- Learning and memory (2)
- Left hemisphere (2)
- Leitlinien (2)
- Leptin (2)
- Leukemia (2)
- Leukemias (2)
- Leukämie (2)
- Linear regression analysis (2)
- Lipid signalling (2)
- Lipidomics (2)
- Liver (2)
- Liver cancer (2)
- Liver injury (2)
- Livestock (2)
- Local climate (2)
- Local therapy (2)
- Lokalrezidiv (2)
- Long-term care (2)
- Long-term potentiation (2)
- Longitudinal (2)
- Low back pain (2)
- Low-molecular-weight heparin (2)
- Low-virulent infection (2)
- Luciferase (2)
- Lucilia sericata (2)
- Lung cancer (2)
- Lungenfunktion (2)
- Lyme disease (2)
- Lymph nodes (2)
- Lymphectasia (2)
- Lymphocytes (2)
- Lymphom (2)
- Lymphoma (2)
- Lysophosphatidic acids (2)
- Lysosome (2)
- M2-PK (2)
- MALAT1 (2)
- MCAO (2)
- MCI (2)
- MICA (2)
- MLH1 (2)
- MLKL (2)
- MMP9 (2)
- MR spectroscopy (2)
- MTT assay (2)
- Macroautophagy (2)
- Magnetic resonance (2)
- Malaria prevalence (2)
- Malnutrition (2)
- Mamma (2)
- Manner of death (2)
- Marburg virus (2)
- Markovianity (2)
- Mastectomy (2)
- Maxillary sinus (2)
- Medical consultation (2)
- Medical diagnostics (2)
- Medication Appropriateness Index (2)
- Medicine (2)
- Medizin (2)
- Meldepflicht (2)
- Membrane potential (2)
- Membrane proteins (2)
- Mesh (2)
- Meta-analysis (2)
- Metabolic syndrome (2)
- Metabolism (2)
- Metastasis (2)
- Metastatic (2)
- Metastatic breast cancer (2)
- Metastatic castration-resistant prostate cancer (2)
- Microglia (2)
- Microsurgery (2)
- Migrants (2)
- Minimal residual disease (2)
- Mitochondrial ROS (2)
- Mitochondrial complex I (2)
- MitraClip (2)
- Mixed methods (2)
- Mobilization (2)
- Model (2)
- Molecular autopsy (2)
- Molecular profiling (2)
- Molecular subtypes (2)
- Monitoring (2)
- Monocytes (2)
- Morbus Basedow (2)
- Morphology (2)
- Morphometry (2)
- Mountain (2)
- Multidrug resistance (2)
- Multiple Sklerose (2)
- Multiple chronic conditions (2)
- Multivariable analysis (2)
- Muskuloskeletale Erkrankungen (2)
- Mutation (2)
- Mutations (2)
- Myalgia (2)
- Myeloid Neoplasia (2)
- Myocardial perfusion (2)
- Myokarditis (2)
- NADH:ubiquinone oxidoreductase (2)
- NCCN (2)
- NCoR1 (2)
- NF-κB pathway (2)
- NFκB (2)
- NIRS (2)
- NK cells (2)
- NOTCH1 (2)
- NS-Medizin (2)
- NS5A (2)
- Nachsorge (2)
- Nachweismethoden (2)
- Nachweisverfahren (2)
- Nadelstichverletzungen (2)
- Necrotizing enterocolitis (2)
- Neoplasms (2)
- Nepal (2)
- Nephrectomy (2)
- Nerve fibers (2)
- Nerve regeneration (2)
- Neugeborenes (2)
- Neural circuits (2)
- Neural stem cells (2)
- Neuroimaging (2)
- Neurologie (2)
- Neuron (2)
- Neuronal morphology (2)
- Neurons (2)
- Neurosurgery (2)
- Neurotoxicity (2)
- Neurotransmitter (2)
- Nevirapine (2)
- Nicotine (2)
- Non-REM sleep (2)
- Non-interventional study (2)
- Normal distribution (2)
- Notaufnahme (2)
- Nox1 (2)
- Nucleic acid biomarkers (2)
- Nuklearmedizin (2)
- Nutrition (2)
- OCT (2)
- Observational (2)
- Obstetrics and gynecology (2)
- Occupational disease (2)
- Olfactory system (2)
- Operation/Chirurgie (2)
- Ophthalmology (2)
- Opioids (2)
- Opportunistic infections (2)
- Optogenetics (2)
- Oral immunotherapy (2)
- Oral surgery (2)
- Ordinary least squares (OLS) (2)
- Organ dysfunction (2)
- Organ dysfunctions (2)
- Organ preservation (2)
- Oroantral (2)
- Orthognathic surgery (2)
- Orthopaedics (2)
- Osteogenic differentiation (2)
- Outcome assessment (2)
- Outcomes research (2)
- Outpatients (2)
- Ovarian cancer (2)
- Oxidative stress (2)
- OxyELITE Pro (2)
- P2X7 receptor (2)
- P600 (2)
- PAC-1 (2)
- PAH (2)
- PARP (2)
- PD-1 (2)
- PD1/ PDL1 (2)
- PD‑L1 (2)
- PET (2)
- PINK1 (2)
- PLGA (2)
- PML (2)
- PRF (2)
- PRNT (2)
- PROTAC (2)
- PTEN (2)
- Pacemaker (2)
- Pain management (2)
- Palliative care (2)
- Palliative care [MeSH] (2)
- Parenteral nutrition (2)
- Parkin (2)
- Parkinson disease (2)
- Particulate matter (2)
- Pathologic complete response (2)
- Pathology (2)
- Patient Blood Management (2)
- Patient manikins (2)
- Patient needs (2)
- Patient preference (2)
- Patient-centred care (2)
- Patientenbedürfnisse (2)
- Patterns of care (2)
- Pediatric infections (2)
- Pelargonium sidoides (2)
- Penile cancer (2)
- Pentaglobin (2)
- Percutaneous coronary intervention (2)
- Perikarditis (2)
- Periodontal therapy (2)
- Periodontal treatment (2)
- Periphere arterielle Verschlusskrankheit (2)
- Peritonitis (2)
- Persistence (2)
- Person-Umwelt-Passung (2)
- Person-environment fit (2)
- Personal- und Organisationsentwicklung (2)
- Personalisierte translationale Therapie (2)
- Petri net (2)
- Pharmacology (2)
- Philadelphia chromosome (2)
- Phylogenetic analysis (2)
- Physical environment (2)
- Plasma (2)
- Plasmodium (2)
- Plasticity (2)
- Plerixafor (2)
- Plk1 inhibitors (2)
- Pneumocystis jirovecii (2)
- Pneumoperitoneum (2)
- Point-of-care testing (2)
- Police (2)
- Polyphenole (2)
- Post-mortem interval (2)
- Post-translational modifications (2)
- Postoperative radiochemotherapy (2)
- Posttraumatic stress disorder (2)
- Posture analysis (2)
- Poverty (2)
- Practical skills (2)
- Predictive coding (2)
- Predominant polarity (2)
- Preeclampsia (2)
- Primary cilium (2)
- Prisoners (2)
- Prisons (2)
- Probability density (2)
- Probability distribution (2)
- Procalcitonin (2)
- Professionalisierung (2)
- Prognosefaktoren (2)
- Prognostic (2)
- Prognostic tool (2)
- Programm (2)
- Prostataspezifisches Antigen (2)
- Prostatic neoplasms (2)
- Proteasome (2)
- Protein Translocation (2)
- Protein biomarkers (2)
- Protein translation (2)
- Protein-Protein Interactions (2)
- Prädiktive Validität (2)
- Prädiktivfaktoren (2)
- Prävalenz (2)
- Pseudomonas aeruginosa (2)
- Psychedelics (2)
- Psychopharmaka (2)
- Pulmonary veins (2)
- Pädiatrie (2)
- Qualitative research (2)
- Quality indicators (2)
- Qualitätsmanagement (2)
- Questionnaire (2)
- Questionnaires (2)
- RAS (2)
- RDoC (2)
- RIPK3 (2)
- RMS (2)
- RNA binding proteins (2)
- RNA interference (2)
- RNA interference (RNAi) (2)
- RNA isolation (2)
- RNA therapy (2)
- RNA-sequencing (2)
- RNAseq (2)
- RNF4 (2)
- ROS1 (2)
- Rab7 (2)
- Radiation (2)
- Radical prostatectomy (2)
- Radiochemotherapy (2)
- Radiologie (2)
- Rainfall (2)
- Random forest (2)
- Randomized controlled trials (2)
- Reanimation (2)
- Recurrence (2)
- Red blood cell transfusion (2)
- Redoxin (2)
- Reform (2)
- Refractory ALL (2)
- Rehabilitation outcome (2)
- Rehabilitationsergebnis (2)
- Rejection (2)
- Relaxometry (2)
- Remuneration (2)
- Renal system (2)
- Reproducibility (2)
- Rescue medication (2)
- Research architecture (2)
- Respiratory chain (2)
- Respiratory distress syndrome (2)
- Respiratory infections (2)
- Restenosis (2)
- Resting-state (2)
- Retina (2)
- Reward (2)
- Rheumatoid Arthritis (2)
- Ribavirin (2)
- Richtlinie (2)
- Risikofaktoren (2)
- Risk assessment (2)
- Risk factor (2)
- Risk stratification (2)
- Rivaroxaban (2)
- Roussel Uclaf Causality Assessment Method (RUCAM) (2)
- Rural area (2)
- S1P lyase (2)
- S1P receptors (2)
- SAMHD1 (2)
- SARS (2)
- SARS coronavirus (2)
- SARS-CoV-2 monitoring (2)
- SARS-CoV-2 testing (2)
- SARS-CoV‑2 (2)
- SARS‐CoV‐2 (2)
- SCC (2)
- SCCHN (2)
- SD-OCT (2)
- SENP (2)
- SF-36 (2)
- SIRS (2)
- SIRT1 (2)
- SKAP1 (2)
- SNP (2)
- SOD (2)
- SPM (2)
- SPTAN1 (2)
- STAT1 (2)
- STING (2)
- SV2A (2)
- Sarcoidosis (2)
- Scheimpflug imaging (2)
- Schilddrüsenfunktion (2)
- Schilddrüsenknoten (2)
- Schizophrenie (2)
- Scientists (2)
- Seizures (2)
- Selbstmanagement (2)
- Self-management (2)
- Self-renewal (2)
- Sensitivität (2)
- Sensory processing (2)
- Serin (2)
- Serodiagnose (2)
- Seroprevalence (2)
- Serum (2)
- Sestrin 2 (2)
- Sexualität (2)
- Short bowel syndrome (2)
- Shunt (2)
- Simulation training (2)
- Skills (2)
- Smoking habits (2)
- Social Media (2)
- Social epidemiology (2)
- Social health determinants (2)
- Social participation (2)
- Socio-economic analysis (2)
- Socioeconomic status (2)
- Sonication (2)
- Sorafenib (2)
- Soziale Ungleichheit (2)
- Specificity (2)
- Speech (2)
- Speech discrimination (2)
- Spezifität (2)
- Sphingolipids (2)
- Spinal cord (2)
- Spine (2)
- Spiroergometrie (2)
- Sprache (2)
- Sprachstörung (2)
- Sprachverstehen (2)
- Sprechen (2)
- Sprechstörung (2)
- Staff development (2)
- Stammzelltransplantation (2)
- Standard endoscopy (2)
- Standard value (2)
- Standardization (2)
- Stem-cell therapies (2)
- Sterblichkeit (2)
- Stereotaxie (2)
- Stickstoffmonoxid (2)
- Strength training (2)
- Streptococcus pneumoniae (2)
- Striatum (2)
- Stroke unit (2)
- Structural plasticity (2)
- Study protocol (2)
- Subarachnoid hemorrhage (2)
- Sudden death (2)
- Suicide pact (2)
- Suizidalität (2)
- Sumatra (2)
- Sunitinib (2)
- Superficial vein thrombosis (2)
- Superoxide (2)
- Supplementation (2)
- Supported decision making (2)
- Supportivtherapie (2)
- Survival analysis (2)
- Survivin (2)
- Sweden (2)
- Synaptic plasticity (2)
- Synaptic transmission (2)
- Synovial sarcoma (2)
- Systematic reviews (2)
- Systemic inflammation (2)
- Systemic therapy (2)
- T-cell (2)
- T-cell receptor (2)
- T-cells (2)
- TBK1 (2)
- TBSS (2)
- TEP (2)
- TF-complexes (2)
- TGF-β1 (2)
- TGFβ (2)
- THR (2)
- TMT (2)
- TRPA1 (2)
- Tailored therapy (2)
- Target identification (2)
- Targeted therapies (2)
- Tattoo (2)
- Teeth (2)
- Tenofovir (2)
- Tetrahydrobiopterin (2)
- Thailand (2)
- Theft (2)
- Thermoregulation (2)
- Thromboembolism (2)
- Thrombolysis (2)
- Thrombophilie (2)
- Thrombotic thrombocytopenic purpura (2)
- Tight junctions (2)
- Toll-like receptor (2)
- Tomography (2)
- Tomography (x-ray computed) (2)
- Tomosynthese (2)
- Tooth loss (2)
- Transcription (2)
- Transcription Factors (2)
- Transfusionsmedizin (2)
- Transgender (2)
- Transmission (2)
- Transplantatabstoßung (2)
- Transplantation (2)
- Traumatic brain injury (2)
- Traumatic injury (2)
- Treatment position (2)
- Treg cell (2)
- Troponin (2)
- Tumor marker (2)
- Tumour immunology (2)
- Tyrosinkinasen (2)
- T‑DM1 (2)
- UGCG (2)
- Ubiquitin Ligase (2)
- Ubiquitylation (2)
- Ulcerative colitis (2)
- Ultrasonography (2)
- Universität Frankfurt am Main (2)
- Unterstützung der Umwelt (2)
- Urethral cancer (2)
- Urology (2)
- Usability (2)
- Uteroglobin (2)
- V4 (2)
- VDR (2)
- VEGF receptors (2)
- VIGALL (2)
- VRE (2)
- VT (2)
- Vaccine (2)
- Vaccine uptake rate (2)
- Validity (2)
- Validität (2)
- Vascular endothelial growth factor (VEGF) (2)
- Vascularization (2)
- Veins (2)
- Vergütung (2)
- Versorgung (2)
- Versorgungsforschung (2)
- Versorgungsstrukturen (2)
- Viral Load (2)
- Viral infection (2)
- Virologie (2)
- Viruslast (2)
- Virussicherheit (2)
- Vision (2)
- Visual acuity (2)
- Visual estimation (2)
- Visual quality (2)
- Vitamin D deficiency (2)
- Vmem (2)
- Volume therapy (2)
- Warburg effect (2)
- Wearable cardioverter-defibrillator (2)
- Web 2.0 (2)
- Weiterbildung (2)
- Western blot (2)
- Wettbewerb (2)
- Wettbewerbsfreiheit (2)
- Wettbewerbsfähigkeit (2)
- White blood cells (2)
- Wnt (2)
- Women (2)
- Working memory (2)
- Wounds (2)
- X-ray crystallography (2)
- Zahnmedizin (2)
- Zebrafish (2)
- Zellkultur (2)
- Zigarette (2)
- Zika fever (2)
- Zink (2)
- Zoopotentation (2)
- Zooprophylaxis (2)
- ablation (2)
- abuse (2)
- acetyl-CoA (2)
- acute lung injury (2)
- acute myeloid leukaemia (2)
- acute respiratory distress syndrome (2)
- adalimumab (2)
- additives (2)
- adenovirus (2)
- adipocytes (2)
- adipose-derived mesenchymal stem cells (2)
- adipose-derived stromal/stem cells (2)
- adjuvant chemotherapy (2)
- admission test (2)
- adolescence (2)
- adoptive cancer immunotherapy (2)
- adoptive immunotherapy (2)
- adult neurogenesis (2)
- advanced (2)
- advanced care planning (2)
- adverse reaction (2)
- age-related macular degeneration (2)
- air flow (2)
- algorithm (2)
- allogeneic hematopoietic stem cell transplantation (2)
- alpelisib (2)
- alpha power (2)
- alpha-synuclein (2)
- amino acids (2)
- amphiregulin (2)
- amyotrophic lateral sclerosis (ALS) (2)
- analgesics (2)
- anaplastic large cell lymphoma (2)
- animal experiment (2)
- animal experiments (2)
- anorexia nervosa (2)
- antibacterial activity (2)
- antibiotic resistance (2)
- antibiotic therapy (2)
- antibody (2)
- antibody test (2)
- anticoagulation (2)
- anticonvulsants (2)
- antiepileptic drug (2)
- antiepileptic drugs (2)
- antifungal therapy (2)
- antigen (2)
- antioxidant (2)
- antiseizure medication (2)
- antisocial behavior (2)
- antiviral drugs (2)
- anxiety (2)
- aptamer (2)
- arachidonic acid (2)
- arousal (2)
- arthritis (2)
- assessment (2)
- astrocytoma (2)
- attachment loss (2)
- audiovisual (2)
- autism (2)
- autoantibodies (2)
- autoimmune diabetes (2)
- autoimmune disease (2)
- autoimmunity (2)
- autologous stem cell transplantation (2)
- automation (2)
- autopsy (2)
- betulinic acid (2)
- bibliometric analysis (2)
- biliary stricture (2)
- bio imaging (2)
- biochemistry (2)
- biofilm (2)
- biologics (2)
- bioluminescence (2)
- biopsy (2)
- biopsy cores (2)
- blood borne infection (2)
- blood flow restriction (2)
- blood pressure (2)
- blood-brain barrier (2)
- bloodborne viruses (2)
- blutübertragbare Infektionskrankheiten (2)
- body plethysmography (2)
- bone healing (2)
- bone marrow microenvironment (2)
- bone marrow mononuclear cells (2)
- bone metabolism (2)
- bone metastasis (2)
- borrelia (2)
- brain cancer (2)
- brain function (2)
- brain networks (2)
- brain states (2)
- brain tumor (2)
- brain-derived neurotrophic factor (2)
- brainstem (2)
- bulimia nervosa (2)
- cART (2)
- cabozantinib (2)
- calcitriol (2)
- campesterol (2)
- cancer cell metabolism (2)
- cancer specific survival (2)
- cancer therapy (2)
- cancer treatment (2)
- cancer-associated fibroblasts (2)
- cancer-specific mortality (2)
- cancer-specific survival (2)
- cannabis (2)
- capsaicin (2)
- carbapenem resistance (2)
- carbapenemase (2)
- carcinoma (2)
- cardiolipin (2)
- cardiovascular (2)
- case-referent study (2)
- caspase-1 (2)
- cataract surgery (2)
- cell culture (2)
- cell motility (2)
- cell proliferation (2)
- cells (2)
- central nervous system (2)
- ceramide (2)
- cerebral hemorrhage (2)
- cerebral protection (2)
- cerebral venous thrombosis (2)
- cerebrovascular disease (2)
- cesarean section (2)
- chemotaxis (2)
- chemotherapy resistance (2)
- chest trauma (2)
- childhood acute myeloid leukemia (2)
- childhood cancer (2)
- children and adolescents (2)
- cholestanol (2)
- cholesterol absorption (2)
- cholesterol synthesis (2)
- chronic granulomatous disease (2)
- chronic hepatitis C (2)
- chronic inflammation (2)
- chronic thromboembolic pulmonary hypertension (2)
- cigarette (2)
- circadian (2)
- circadian rhythm (2)
- circadian rhythms (2)
- circular RNA (2)
- cisplatin resistance (2)
- citation (2)
- cleaning (2)
- clinical immunology (2)
- clinical isolates (2)
- clinical studies (2)
- clinically important restrictions and symptoms (2)
- coagulopathy (2)
- cochlea (2)
- colon carcinoma cells (2)
- colorectal cancer (CRC) (2)
- colorectal carcinoma (2)
- combination therapies (2)
- communication (2)
- comorbidities (2)
- comorbidity (2)
- complementary and alternative medicine (2)
- complementary medicine (2)
- complex I (2)
- complex systems (2)
- compliance (2)
- computational neuroscience (2)
- computer-assisted (2)
- concordance (2)
- consensus (2)
- constipation (2)
- contemporary (2)
- continuous performance test (2)
- convulsive seizures (2)
- coping (2)
- corneal edema (2)
- corneal transplantation (2)
- corona virus (2)
- coronary artery bypass graft surgery (2)
- coronary artery disease (2)
- corpus callosum (2)
- cost-effective (2)
- counseling (2)
- criticality (2)
- cryoballoon (2)
- cryopreservation (2)
- cyclooxygenase (2)
- cyclosporin A (2)
- cyclosporine (2)
- cytochrome P450 2E1 (2)
- cytokine (2)
- cytotoxic T cells (2)
- dabrafenib (2)
- data quality (2)
- deafness (2)
- decision making (2)
- decompensated liver cirrhosis (2)
- delay (2)
- delirium (2)
- dental assistant (2)
- dental assistants (2)
- dentists (2)
- dentoalveolar surgery (2)
- desensitization (2)
- detoxification (2)
- deubiquitinase (DUB) (2)
- diet (2)
- dietary supplements (2)
- dihydroceramide (2)
- disease burden (2)
- disease models (2)
- disease progression (2)
- disintegration (2)
- dislocation (2)
- distress (2)
- docetaxel (2)
- doxycycline (2)
- drug release (2)
- drug-induced liver injury (2)
- drugs (2)
- dual task (2)
- dysphagia (2)
- e-Learning (2)
- eLearning (2)
- eating disorders (2)
- economic burden (2)
- eicosanoids (2)
- elderly patients (2)
- electrocardiography (2)
- electron transport chain (2)
- emergency care (2)
- encoding (2)
- endodontic curriculum (2)
- endodontic education (2)
- endothelial (2)
- endothelial cell (2)
- endovascular treatment (2)
- entorhinal cortex lesion (2)
- ephrinB2 (2)
- epidemics (2)
- epidermal growth factor (2)
- epigenetic (2)
- epileptic encephalopathy (2)
- epileptogenesis (2)
- epithelial to mesenchymal transition (2)
- erectile dysfunction (2)
- erythropoietin (2)
- esophageal cancer (2)
- euthymic (2)
- evolution (2)
- expertise (2)
- extraversion (2)
- factor H (2)
- fall (2)
- fasting (2)
- fecal occult blood test (2)
- feedback (2)
- female subjects (2)
- femoral artery ligation (2)
- ferric carboxymaltose (2)
- fibrinolysis (2)
- focal therapy (2)
- follow‑up (2)
- fortgeschritten (2)
- fracture (2)
- functional genetics (2)
- functional genomics (2)
- fungi (2)
- funktionelle Bildgebung (2)
- furcation involvement class III (2)
- fusion (2)
- fusion biopsy (2)
- fäkaler okkulter Stuhltest (2)
- gait analysis (2)
- galactography (2)
- galactomosynthesis (2)
- gene signature (2)
- genetic diversity (2)
- genetic variants (2)
- genome (2)
- glucose metabolism (2)
- growth factor (2)
- guided bone regeneration (2)
- haemophilia (2)
- haemophilia A (2)
- head and neck neoplasms (2)
- head and neck squamous cell carcinoma (2)
- health (2)
- health care (2)
- health information exchange (2)
- health services research (2)
- healthcare personnel (2)
- healthcare workers (2)
- hedgehog signaling (2)
- hematopoiesis (2)
- hematopoietic stem cells (2)
- hemodynamic (2)
- hemolysis (2)
- hemorrhagic transformation (2)
- hepatic encephalopathy (2)
- hepatitis B virus (2)
- hepatotoxicity (2)
- herbal hepatotoxicity (2)
- herpes zoster (2)
- hip (2)
- hippocampal sclerosis (2)
- histamine (2)
- histological validation (2)
- histone deacetylase (2)
- histone deacetylase inhibitor (2)
- homeostatic plasticity (2)
- hormones (2)
- human biology and medicine (2)
- human cytomegalovirus (2)
- human genomics (2)
- human immunodeficiency virus (2)
- humans (2)
- hyperalgesia (2)
- hyperhomocysteinemia (2)
- hypertension (2)
- iCBT (2)
- iDILI (2)
- iPS (2)
- idiopathic pulmonary fibrosis (2)
- immune system (2)
- immune therapy (2)
- immunocytochemistry (2)
- immunologische Methoden (2)
- in-cabin exposure (2)
- induced membrane (2)
- induction chemotherapy (2)
- infections (2)
- infectious disease (2)
- infectivity (2)
- infiltration (2)
- inhibitors (2)
- injury (2)
- inner ear (2)
- insulin (2)
- integrated stress response (2)
- integration (2)
- integrative medicine (2)
- interferon (2)
- interferon gamma (2)
- interleukin-18 (2)
- interleukin-4 (2)
- intermediate risk (2)
- international (2)
- internet (2)
- intracranial hemorrhage (2)
- irritable bowel syndrome (2)
- job-exposure matrix (2)
- joint contact forces (2)
- keratinized mucosa (2)
- kidney cancer (2)
- kidney function (2)
- kidney transplantation (2)
- kinase inhibitor (2)
- kinase regulation (2)
- kinematic analysis (2)
- kinematics (2)
- klinischer Nutzen (2)
- knowledge discovery (2)
- laboratory testing (2)
- lapatinib (2)
- lathosterol (2)
- layer-specificity (2)
- lenalidomide (2)
- leukodystrophy (2)
- leukopenia (2)
- leukotriene (2)
- lifestyle intervention (2)
- lipid metabolism (2)
- lipidomics (2)
- lipoproteins (2)
- liver damage (2)
- liver disease (2)
- liver metastases (2)
- local control (2)
- local information dynamics (2)
- localized prostate cancer (2)
- long-term outcome (2)
- long-term potentiation (2)
- long-term prophylaxis (2)
- long-term success (2)
- long-term survival (2)
- long-term tooth survival (2)
- longevity (2)
- low molecular weight heparin (2)
- low-glycaemic meal replacement (2)
- lymph node dissection (2)
- lymphocytes (2)
- mRNA stability (2)
- mTOR inhibitor (2)
- maintenance (2)
- malignancy (2)
- mammary carcinoma (2)
- mandatory reporting (2)
- marginal bone loss (2)
- mast cells (2)
- mathematical models of viral RNA cycle (2)
- matrix (2)
- medical studies (2)
- medication review (2)
- medulloblastoma (2)
- melatonin (2)
- membrane protein complex (2)
- mental health (2)
- mesenchymal stromal cell (2)
- meta-analysis (2)
- metastatic castration-resistant prostate cancer (2)
- methylprednisolone (2)
- miR (2)
- miR-181 (2)
- miR-21 (2)
- microdosing (2)
- microenvironment (2)
- microsurgery (2)
- minimalinvasive Biopsie (2)
- minimally invasive biopsies (2)
- mobile air quality study (2)
- modularity (2)
- molecular dynamics (2)
- molecular marker (2)
- molecular mimicry (2)
- molecular typing (2)
- morphogenesis (2)
- morphometry (2)
- mouse models (2)
- mucormycetes (2)
- multicentre study (2)
- multidetector computed tomography (2)
- multinucleated giant cells (2)
- multiple trauma (2)
- multisensory integration (2)
- musculoskeletal (2)
- musculoskeletal modeling (2)
- music (2)
- myelodysplastic syndrome (2)
- nanoparticles (2)
- natural product (2)
- ncRNA (2)
- needlestick injury (2)
- neoadjuvante Chemotherapie (2)
- neoadjuvante Therapie (2)
- nephropathy (2)
- network analysis (2)
- neurocognition (2)
- neurocognitive (2)
- neurodegenerative diseases (2)
- neuroendocrine (2)
- neurogenesis (2)
- neuromodulation (2)
- neurooncology (2)
- neurophysiology (2)
- neuroprotection (2)
- neuroticism (2)
- neutropenia (2)
- neutrophils (2)
- next generation sequencing (2)
- next generation sequencing (NGS) (2)
- niche (2)
- nivolumab (2)
- non-small cell lung cancer (2)
- non-small-cell lung cancer (2)
- nursery schools (2)
- nutlin-3 (2)
- occupational exposure (2)
- occupational health (2)
- olfaction (2)
- oligomerisation (2)
- omega-3 fatty acids (2)
- oncogene (2)
- oncogenes (2)
- oncomodulation (2)
- optical imaging (2)
- oral and maxillofacial surgery (2)
- oscillations (2)
- osteogenesis (2)
- other-cause mortality (2)
- out-patient paediatrics (2)
- p16 (2)
- paclitaxel (2)
- pain management (2)
- paired associative stimulation (2)
- palatal tremor (2)
- partial information decomposition (2)
- particle size distribution (2)
- passive smoke (2)
- pathology (2)
- patient (2)
- patient centered care (2)
- patient preferences (2)
- patient triage (2)
- patient-reported outcomes (2)
- pediatric surgery (2)
- pelvic packing (2)
- penile cancer (2)
- peptide aptamer (PA) (2)
- peri-implant diseases (2)
- pericytes (2)
- periodontal diseases (2)
- periodontitis stage III and IV (2)
- peri‐implantitis (2)
- pertussis (2)
- phagocytes (2)
- pharmacogenetics (2)
- pharmacokinetics (2)
- pharmacoresistance (2)
- pharmacovigilance (2)
- phosphate (2)
- photodynamic therapy (2)
- physiotherapy (2)
- polo-like kinase 1 (2)
- poly(lactic-co-glycolic acid) (PLGA) (2)
- polygenic risk score (2)
- polymerase chain reaction (2)
- polymorphism (2)
- polyphenols (2)
- population dynamics (2)
- post-translational modifications (2)
- postoperative complications (2)
- postoperative pain (2)
- posttraumatic stress disorder (2)
- preclinical (2)
- prediction (2)
- predictive (2)
- predictive factors (2)
- preterm birth (2)
- primary sclerosing cholangitis (2)
- process evaluation (2)
- prognostic (2)
- prognostic value (2)
- progranulin (2)
- prostaglandin E (2)
- prostate carcinoma cells (2)
- proteasome (2)
- proteasome inhibitor (2)
- protein kinase (2)
- protein phosphorylation (2)
- protein quality control (2)
- protein-protein interaction (2)
- protein-rich (2)
- proteostasis (2)
- proximal tubule (2)
- psychiatric disorders (2)
- psychiatry (2)
- psychophysiology (2)
- psychosis (2)
- pulmonary embolism (2)
- pulmonary hypertension (2)
- pulmonary vein isolation (2)
- pulse wave velocity (2)
- qRT-PCR (2)
- quality (2)
- quality management (2)
- quantum biology (2)
- radical cystectomy (2)
- radioimmunotherapy (2)
- randomized (2)
- randomized controlled trial (2)
- rare disease (2)
- rare diseases (2)
- rat model (2)
- re-osseointegration (2)
- real-world (2)
- real-world data (2)
- recommendations (2)
- reference values (2)
- refractory (2)
- regenerative medicine (2)
- regulatory T cell (2)
- relapse (2)
- relaxometry (2)
- renal failure (2)
- renal tubular epithelial cells (2)
- research (2)
- residual myometrial thickness (2)
- resistance mutation (2)
- resistant cell lines (2)
- resolution (2)
- resolution of inflammation (2)
- respiratory chain (2)
- respiratory failure (2)
- respiratory infections (2)
- respiratory tract infection (2)
- resting-state (2)
- resveratrol (2)
- revision surgery (2)
- ribavirin (2)
- risk assessment (2)
- risk group (2)
- risk management (2)
- risk prediction (2)
- saliva (2)
- sarcoma (2)
- scaffold (2)
- school-based prevention (2)
- scientometrics (2)
- scientometry (2)
- second-hand smoke (2)
- second-line (2)
- secondary data analysis (2)
- secretion (2)
- secretome (2)
- secukinumab (2)
- selection (2)
- sensory neuropathy (2)
- serine protease (NS3-4A) (2)
- sex differences (2)
- short essay questions (2)
- shunt (2)
- siRNA (2)
- signal transducer and activator of transcription 5 (Stat5) (2)
- signature (2)
- single-sided deafness (2)
- sitosterol (2)
- skin (2)
- smoking cessation (2)
- smooth muscle cells (2)
- soft tissue (2)
- soluble MICA (2)
- sound-induced flash illusion (2)
- speech (2)
- speech and language disorder (2)
- speech perception (2)
- sphingosine 1-phosphate receptor (2)
- sphingosine kinase (2)
- spiking neural networks (2)
- spinal dural leaks (2)
- spine head (2)
- spreadsheet (2)
- squamous cell carcinoma (2)
- stability (2)
- stage (2)
- standard value (2)
- starvation (2)
- stationarity (2)
- steatosis (2)
- stem cell therapy (2)
- stem cells (2)
- stereotactic radiosurgery (2)
- stress granules (2)
- studies (2)
- study protocol (2)
- sub-lineage (2)
- subchondral bone (2)
- suicide (2)
- superficial siderosis (2)
- supplementation (2)
- supportive therapy (2)
- survival rate (2)
- survivin (2)
- sympathetic nervous system (2)
- symptoms (2)
- synaptopodin (2)
- synchronization (2)
- synchrony (2)
- synergy (2)
- synovium (2)
- tDCS (2)
- telemedicine (2)
- temperature (2)
- temsirolimus (2)
- test methods (2)
- testing (2)
- testosterone (2)
- tetracycline (2)
- tetrahydrobiopterin (2)
- tetrahydrocannabinol (2)
- therapy resistance (2)
- thromboembolism (2)
- thrombophilia (2)
- tissue Doppler imaging (2)
- tobacco (2)
- tobacco smoke (2)
- tolerability (2)
- tolerance (2)
- tomosynthesis (2)
- tooth transplantation (2)
- total hip replacement (2)
- tracking (2)
- traffic emissions (2)
- trafficking (2)
- transcription factors (2)
- transcriptomics (2)
- transforming growth factor-β (2)
- translation (2)
- trastuzumab (2)
- treatment/therapy (2)
- triple-negative breast cancer (2)
- trophoblast (2)
- trophoblasts (2)
- tumor (2)
- tumor angiogenesis (2)
- tumor infiltrating lymphocytes (2)
- tumor necrosis factor (2)
- tumor stroma (2)
- tumor suppressor (2)
- tumor-infiltrating lymphocytes (2)
- type 1 diabetes (2)
- undergraduate medical education (2)
- unilateral hip osteoarthritis (2)
- upgrading (2)
- urethral stricture (2)
- urethroplasty (2)
- urinary incontinence (2)
- urological cancer (2)
- ursodeoxycholic acid (2)
- ustekinumab (2)
- uteroglobin (2)
- vaccination rates (2)
- vaccine uptake rates (2)
- validity (2)
- vascular biology (2)
- vascular disease (2)
- vasodilation (2)
- venous thrombosis (2)
- ventral striatum (2)
- very high risk (2)
- virus (2)
- viruses (2)
- visual cortex (2)
- vitamin B deficiency (2)
- von Willebrand disease (2)
- von Willebrand factor (2)
- walking (2)
- weight loss (2)
- weight reduction (2)
- white matter hyperintensity (2)
- within-host viral modelling (2)
- women (2)
- workflow (2)
- zebrafish (2)
- Ärztliche Aufklärung (2)
- "NS"-Euthanasie (1)
- "alternative" technology (1)
- "conventional" analysis technics (1)
- (cardiac) surgery (1)
- (lyso)phospholipids (1)
- (novel) brominated flame retardants ((N)BFR) (1)
- (sub-) luxation (1)
- 1,2-dichloroethane (1)
- 1,25-Dihydroxyvitamin D (1)
- 1-propanol (1)
- 14-3-3 gene family (1)
- 15-PGDH (1)
- 16 segment AHA model (1)
- 16S rRNA sequencing (1)
- 16p11.2 (1)
- 17-AAG (1)
- 177Lu-PSMA (1)
- 17‐OH itraconazole (1)
- 18-Hydroxycorticosteron (1)
- 18-OH corticosterone (1)
- 19F MR spectroscopy (1)
- 1H MR spectroscopy (1)
- 1H NMR; Conformational Properties (1)
- 1α,25(OH)2D3 (1)
- 2-AG (1)
- 2-Arachidonoyl glycerol (1)
- 2-deoxy-d-glucose (1)
- 2-deoxyglucose (2-DG) (1)
- 2-hydroxyglutarate (1)
- 2019-nCoV (1)
- 223Radium-dichloride (1)
- 26 LncRNA (1)
- 2‑methoxyestradiol (1)
- 2′,3′-cGAMP (1)
- 3 mm RAS instruments (1)
- 3 mm instruments (1)
- 3-hydroxyanthranilic acid (1)
- 3-hydroxyisovaleryl carnitine (1)
- 3-year survival (1)
- 32D progenitor cells (1)
- 3Cs technology (1)
- 3D culture (1)
- 3D gait analysis (1)
- 3D laparoscopy (1)
- 3D printed cell-free scaffold (1)
- 3D printing using composite resin (1)
- 3D printing using zirconia (1)
- 3D spatiotemporal resolved mathematical models (1)
- 3D tissue models (1)
- 3D-Druck (1)
- 3D-models (1)
- 3D-printing (1)
- 3T3-L1 mouse fibroblasts (1)
- 3years (1)
- 4-1BB (1)
- 4-FA (1)
- 4-fluoroamphetamine (1)
- 5 lipoxygenase (1)
- 5' UTR (1)
- 6-Schritt-Methode (1)
- 9-aminoacridine (1)
- 90% or more improvement in baseline Psoriasis Area and Severity Index (1)
- 98/79/EC (1)
- 99mTc-MIBI (1)
- 99mTc-pertechnetate (1)
- A-FFIP (1)
- A-PRF+ (1)
- A2BP1 (1)
- A375 human melanoma cell line (1)
- A375 human melanoma cells (1)
- A498 cells (1)
- A549 (1)
- AA-amylodosis (1)
- AAA+ disaggregase (1)
- AABR (1)
- AB-serum (1)
- ABC transporter (1)
- ABCB5 (1)
- ABS (1)
- ABT-737 (1)
- ACAD (1)
- ACE inhibitor (1)
- ACE-Bestimmung (1)
- ACE-inhibitor (1)
- ACI-Rat (1)
- ACI-Ratte (1)
- ACKR (1)
- ACT-777991 (1)
- ACTH (1)
- ACURATE neo (1)
- ADAM-17 (1)
- ADAM10 (1)
- ADAMTS-13 (1)
- ADAMTS13 (1)
- ADC (1)
- ADC-Karte (1)
- ADC-Map (1)
- ADCC (1)
- ADGRE1 (1)
- ADHD differential diagnosis (1)
- AFS (1)
- AGC kinase (1)
- AGMO (1)
- AICAR (1)
- AIH immunopathogenesis (1)
- AIS (1)
- AJAP1 (1)
- AKT (1)
- AKT signaling (1)
- AKT-mTOR pathway (1)
- ALD (1)
- ALDH2 (1)
- ALF (1)
- ALK gene (1)
- ALK-rearranged NSCLC (1)
- ALLO (1)
- AMD3100 (1)
- AML – acute myeloid leukemia (1)
- AMP-activated kinase (1)
- AMP-activated kinase (AMPK) (1)
- AO-PCCF (1)
- AOSpine (1)
- AOSpine injury score (1)
- APMPPE - acute posterior multifocal placoid pigment epitheliopathy (1)
- APP (1)
- APP processing (1)
- APRI (1)
- APS (1)
- APT-CEST (1)
- ARA (1)
- ARID5B (1)
- ASA (1)
- ASA-Klassifikation (1)
- ASA404 (1)
- ASAP (1)
- ASC (1)
- ASCT (1)
- ASD-specific (1)
- ASO (1)
- ASPECTS (1)
- AT-101 (1)
- AT1 receptor antagonist (1)
- ATG3 (1)
- ATG4 (1)
- ATG8 (1)
- ATO (1)
- ATXN2 (1)
- AU-rich element (1)
- AVM hemorrhage (1)
- AZD7762 (1)
- Aachen <2012> (1)
- Abatacept (1)
- Abdominal infections (1)
- Abdominal surgery (1)
- Abdominal trauma (1)
- Abductor pollicis longus (1)
- Abiraterone acetate (1)
- Abl kinase inhibitors (1)
- Ablation (1)
- Ablation Techniques (1)
- Abrasion (1)
- Abruf (1)
- Absenteeism (1)
- Absolute quantification (1)
- Abstrich <Medizin> (1)
- Abstrichisolate (1)
- Abtötung (1)
- Abtötungskinetik (1)
- Abusive head trauma (AHT) (1)
- Academic health centres (1)
- Academics (1)
- Accelerometry (1)
- Accessibility (1)
- Access® immunoassay system (1)
- Access®-Immunoassaysystem (1)
- Accident (1)
- Accidents (1)
- Accumulated degree days (1)
- Acellular dermis (1)
- Acenocoumarol (1)
- Acer platanoides (1)
- Acetabulumdefekt (1)
- Acetylsalicylsäure (1)
- Achtundsechzig (1)
- Achtundsechziger (1)
- Acid ceramiase (1)
- Acide gamma-aminobutyrique (1)
- Acidic Dissociation (1)
- Acidic Amino Acids (1)
- Acquired drug resistance (1)
- Acquired resistance (1)
- Acrylamid (1)
- Actaea cimicifuga (1)
- Actin (1)
- Actinomycin D (1)
- Action potential (1)
- Activated partial thromboplastin time (1)
- Active middle ear implants (1)
- Activity control (1)
- Acute (1)
- Acute HIV infection (1)
- Acute Hemiparesis (1)
- Acute Myeloid Leukemia (1)
- Acute appendicitis (1)
- Acute bronchitis (1)
- Acute calcolous cholecystitis (1)
- Acute coronary syndrome (1)
- Acute cough (1)
- Acute elbow dislocation (1)
- Acute heart failure (1)
- Acute hospital (1)
- Acute injuries (1)
- Acute kidney failure (1)
- Acute leukemia (1)
- Acute renal failure (1)
- Acute respiratory distress syndrom (1)
- Acute-on-chronic subdural hematoma (1)
- Adeno associated virus (1)
- Adenylate Kinase (1)
- Adenylyl cyclase (1)
- Adherence junctions (1)
- Adhesins (1)
- Adhesion Factor (1)
- Adhärenz (1)
- Adipose tissue-derived mesenchymal stem cells (1)
- Adipositas Chirurgie (1)
- Adiposity (1)
- Adjustment of dosage at steady state (1)
- Adjuvant procedure (1)
- Adjuvant therapies (1)
- Adjuvante Therapie (1)
- Adjuvantes Verfahren (1)
- Administrative claims data (1)
- Adolescence (1)
- Adoptive Immuntherapie (1)
- Adoptivkind (1)
- Adrenal crisis (1)
- Adrenale Krise (1)
- Adrenalektomie (1)
- Adrenocorticotropic hormone (1)
- Adrenokortikotropes Hormon (1)
- Adult (1)
- Adult T-cell acute lymphoblastic leukemia (1)
- Adult-onset ADHD (1)
- Advanced biliary tract cancer (1)
- Advanced breast cancer (1)
- Advanced glycation endproducts (1)
- Advanced stage (1)
- Adverse effects (1)
- Aeroplysinin-1 (1)
- Aerosolspektrometrie (1)
- Affect (1)
- Affective Misattribution Procedure (1)
- Affective disorders (1)
- Affinity Chromatography (1)
- Africa (1)
- Afrikanische Schlafkrankheit (1)
- Ag-RDT (1)
- Aganglionosis (1)
- Agardiffusion (1)
- Age (1)
- Age determination (1)
- Age determination by skeleton (1)
- Ageing (1)
- Aggregation (1)
- Aggression (1)
- Aggressive periodontitis (1)
- Agitation (1)
- Agoraphobia (1)
- Agreement (1)
- Air traffic (1)
- Airport-related emissions (1)
- Airways (1)
- Akkreditierung (1)
- Akt-mTOR pathway (1)
- Akt-mTOR signaling (1)
- Aktivierte partielle Thromboplastinzeit (1)
- Aktivität (1)
- Akute (1)
- Akute Leukämie (1)
- Akute Niereninsuffizienz (1)
- Akute Verletzungen (1)
- Akutes Koronarsyndrom (1)
- Akzelerationszeit (1)
- Albumin (1)
- Albumin ratio (1)
- Aliphatic halogenated hydrocarbons (1)
- Alisertib (1)
- Alkaline phosphatase (1)
- Alkalische Phosphatase (1)
- Alkaloid (1)
- Alkohol (1)
- Alkoholiker (1)
- Alkoholismus (1)
- Alkoholmissbrauch (1)
- Alkylating NAD-Analogs (1)
- All oral (1)
- All-oral therapy (1)
- All-trans retinoic acid (1)
- Allergen (1)
- Allergen immunotherapy (1)
- Allergen-Testung (1)
- Allergenprovokation (1)
- Allergic rhinitis (1)
- Allergische Rhinitis (1)
- Allergisches Asthma (1)
- Allergoid (1)
- Allgemeinmedizin Forschung (1)
- Allochromatium vinosum (1)
- Allogeneic (1)
- Allogeneic Stem Cell Transplantation (SCT) (1)
- Allogeneic hematopoietic stem (1)
- Allogeneic stem cell transplantation (1)
- Allograft bone block (1)
- Allopregnanolon (1)
- Alpha oscillations (1)
- Alpha power (1)
- Alpha-fetoprotein (AFP) (1)
- Alpha-synuclein (1)
- Alpha-synuclein deficiency (1)
- Alte Medizin (1)
- Altenheim (1)
- Alternative oxidase (1)
- Alveolar ridge augmentation (1)
- Alzheimer’s dementia (1)
- Ambient air (1)
- Ambroxol (1)
- Ambulante Pflege (1)
- Ambulatory Assessment (1)
- Ameloblastoma (1)
- Amino acid analysis (1)
- Amino acids (1)
- Aminosäuremetabolismus (1)
- Aminosäuren (1)
- Aminotransferases (1)
- Amiodaron (1)
- Amisulpride (1)
- Amitriptyline (1)
- Amizon (1)
- Amniotic fluid (1)
- Amphetamine (1)
- Amsterdam-Kriterien (1)
- Amygdala (1)
- Amyloid precursor protein (1)
- Amyloid-beta 42 (1)
- Amyotrophic lateral sclerosis (1)
- Anaesthesia (1)
- Anakinra (1)
- Analkarzinom (1)
- Analogue modelling (1)
- Analschleimhautabstrich (1)
- Analysis tool (1)
- Anamneseerhebung (1)
- Anaplastic astrocytoma (1)
- Anatomic competence (1)
- Anatomie (1)
- Anatomie und Histologie (1)
- Andersen-Tawil syndrome (1)
- Anderson–Fabry (1)
- Andexanet alpha (1)
- Andropogon virginicus (1)
- Anemia management (1)
- Anerkennung (1)
- Anesthesia, Intravenous (1)
- Aneurysm (1)
- Aneurysmal subarachnoid hemorrhage (1)
- Aneurysms (1)
- Anfall (1)
- Anfallsserie (1)
- Anfallsunterbrechende (1)
- Anfallsunterbrechende Medikamente (1)
- Angeborene Fehlbildungen (1)
- Angiectasia (1)
- Angiodysplasia (1)
- Angioedema (1)
- Angiogenèse (1)
- Angiomyolipoma (1)
- Angioplasty (1)
- Angiotensin Converting Enzyme (1)
- Angiotensin-converting enzyme (1)
- Angststörungen (1)
- Animal disease models (1)
- Animal experiment (1)
- Animal wings (1)
- Anion and Zwitterion Transport (1)
- Anisotrope Diffusion (1)
- Ankle arthrometer (1)
- Ankylosierende Spondylitis (1)
- Ankylosing spondylitis (1)
- Anomalie <Medizin> (1)
- Anomalous venous atrial connections (1)
- Anopheles (1)
- Anorexia Nervosa (1)
- Anosmia (1)
- Antagonist (1)
- Antarctic marine sponges (1)
- Anterior cingulate cortex (1)
- Anterior cruciate ligament reconstruction (1)
- Anti platelet therapy (1)
- Anti-CMV IgG (1)
- Anti-Cardiolipin-Antikörper (1)
- Anti-Müller-Hormon (1)
- Anti-Phospholipid-Syndrom (1)
- Anti-TNF (1)
- Anti-inflammatory (1)
- Anti-rheumatic agents (1)
- Anti-tumor immunity (1)
- Antiangiogenesis (1)
- Antibiotic (1)
- Antibiotic generic drugs (1)
- Antibiotic steward-ship (1)
- Antibiotic stewardship (1)
- Antibiotic therapy (1)
- Antibiotika (1)
- Antibiotikaresistenz (1)
- Antibody avidity (1)
- Antibody detection (1)
- Antibody isotypes (1)
- Antibody therapy (1)
- Antibody-mediated rejection (1)
- Anticholinergic (1)
- Anticoagulant (1)
- Anticoagulants (1)
- Anticoagulants [MeSH] (1)
- Anticonvulsant (1)
- Antidepressant (1)
- Antidepressiva (1)
- Antifungal agents (1)
- Antigen (1)
- Antigen CD62 (1)
- Antigen- und Nukleinsäurenachweis (1)
- Antigen-presenting cells (1)
- Antigene Virale/Immunologie (1)
- Antigennachweis (1)
- Antigens (1)
- Antigens,Viral/immunology (1)
- Antihormone therapy (1)
- Antikörpernachweis (1)
- Antimicrobial resistance (1)
- Antineoplastic agents (1)
- Antioxidant (1)
- Antioxidants (1)
- Antiplatelet therapy (1)
- Antiproliferative (1)
- Antireflux surgery (1)
- Antirheumatic agents (1)
- Antiseizure medication (1)
- Antiseizure medication Instructions for action (1)
- Antithrombotic therapy (1)
- Antivenom (1)
- Antiviral agents (1)
- Antiviral immune response (1)
- Antiviral response (1)
- Antiviral treatment (1)
- Antivirale Therapie (1)
- Anura (1)
- Anwendbarkeit (1)
- Anxiolytic pharmacological therapy (1)
- Anzapfsyndrom (1)
- Aortic Valve Replacement (1)
- Aortic aneurysm (1)
- Aortic arch replacement (1)
- Aortic debranching (1)
- Aortic input function (1)
- Aortic stiffness (1)
- Aortic valve sparing (1)
- Aperiodic (1)
- Apes (1)
- Aphantasia (1)
- Aphasia (1)
- Aphasie (1)
- Apoptose (1)
- Apoptotic cell death (1)
- Appendectomy (1)
- Aquaporins (1)
- Ara h2-specific IgE (1)
- Arabin pessary (1)
- Arabin-Pessar (1)
- Arbeit (1)
- Arbeitsbedingt erworbene Infektion (1)
- Arbeitsflexibilisierung (1)
- Arbeitsmedizin (1)
- ArchT (1)
- Archaebacterial Lipids (1)
- Architektur (1)
- Arcuate fascicle (1)
- Area deprivation (1)
- Argatroban (1)
- Arms (1)
- Aromatase Inhibitors (1)
- Aromatase inhibitors (1)
- Arrhythmia syndromes (1)
- Arrhythmia/all (1)
- Artemether-lumefantrine (1)
- Artemisinin-combination-therapy (1)
- Arteria ophthalmica (1)
- Arterielle Thrombose (1)
- Arterielle Verschlusskrankheit (1)
- Arteriogenesis (1)
- Arteriosclerosis (1)
- Arteriovenous malformation (1)
- Artesunate (1)
- Arthrodese (1)
- Arthroscopy (1)
- Arthroskopischer Bankart-Repair (1)
- Artificial feeding bioassays (1)
- Arzt-Patient-Beziehung (1)
- Asian bush mosquito (1)
- Asparaginase (1)
- Aspergillosis (1)
- Aspergillus species (1)
- Aspirin (1)
- Assay variation (1)
- Assessment of care (1)
- Asthma and allergic disorders (1)
- Asthmadiagnostik (1)
- Astrocytoma (1)
- Astrocytoma grades (1)
- Astrozyten (1)
- Ataxia score (1)
- Atazanavir (1)
- Atelopus carbonerensis (1)
- Atelopus mucubajiensis (1)
- Atelopus tamaense (1)
- Atemtest (1)
- Atención centrada en el paciente (1)
- Atherosklerose (1)
- Athlete (1)
- Atm (1)
- Atomoxetine (1)
- Atrial Fibrillation (1)
- Atrial appendage occlusion (1)
- Atrial fibrillation classification (1)
- Atrial function (1)
- Attack (1)
- Attention Deficit Hyperactivity Disorder (1)
- Attention Deficit Hyperactivity Disorder (ADHD) (1)
- Attention deficit (1)
- Attention-Deficit/Hyperactivity Disorder (ADHD) (1)
- Attention-deficit / hyperactivity disorder (1)
- Attentional bias (1)
- Atxn2 (1)
- Audio equipment (1)
- Audio signal processing (1)
- Audiologie (1)
- Audiology (1)
- Audition (1)
- Auditory (1)
- Auditory cortex (1)
- Aufmerksamkeit (1)
- Aufmerksamkeitsleistung (1)
- Augenerkrankungen (1)
- Auric nanoparticles (1)
- Aurora (1)
- Aurora Ax (1)
- Aurora kinase (1)
- Aurora kinase inhibitor (1)
- Ausbildung (1)
- Australia (1)
- Autism Spectrum disorder (1)
- Autism spectrum disorders (1)
- Autismus-Spektrum-Störungen (1)
- Autistic Behavior (1)
- Autistic disorder (1)
- Auto transfusion (1)
- Auto-ML (1)
- Autogenous bone block (1)
- Autoimmun (1)
- Autoimmune Disease (1)
- Autoimmune encephalomyelitis (1)
- Autoimmune response (1)
- Autoimmune vasculopathy (1)
- Autoimmunität (1)
- Autologous stem cell transplantation (1)
- Automated Tube Potential Selection (1)
- Automated sRNA analysis (1)
- Automatic Environmental Tobacco Smoke Emitter (1)
- Automatisation (1)
- Autonomes Nervensystem (1)
- Autonomic nervous system (1)
- Autophagie (1)
- Autoregulation (1)
- Autosomal recessive cutis laxa type 1C (1)
- Awareness (1)
- Awareness campaign (1)
- Axial spondyloarthritis (1)
- Axiale Spondyloarthritis (1)
- Axiales Längenwachstum (1)
- Axiography (1)
- Axon (1)
- Axons (1)
- Ayahuasca (1)
- Ayurveda (1)
- Ayurvedic herbal products (1)
- Azacitidine (1)
- Azan (1)
- Azan trichrome stain (1)
- Azathioprin (1)
- Azathioprine (1)
- Azidothymidine (1)
- B cell cancer (1)
- B cell differentiation (1)
- B cell malignancies (1)
- B cell precursor acute lymphoblastic leukemia (1)
- B cell receptor (1)
- B cell subpopulations (1)
- B-cell (1)
- B-cell antigen receptor (1)
- B-cell immunology (1)
- B-cell non-Hodgkin lymphoma (1)
- B-cell receptor (1)
- B-cell transcription factors (1)
- B.1.1.529 (1)
- B.1.1.7 (1)
- B.1.617.1 (1)
- B.1.617.2 (1)
- B16 cells (1)
- B3GNT2 (1)
- BA.4 (1)
- BA.5 (1)
- BACTEC™ 9000 (1)
- BATF3 (1)
- BBB (1)
- BCG (1)
- BCG-Therapie (1)
- BCL-2 (1)
- BCL11b (1)
- BCORL1 (1)
- BCR signaling (1)
- BCR-ABL (1)
- BEACOPP (1)
- BET proteins (1)
- BEZ235 (1)
- BFIS (1)
- BG-index (1)
- BH3 mimetics (1)
- BH4 (1)
- BI1361849 (1)
- BIAM switch assay (1)
- BIAM-switch (1)
- BIRC5 (1)
- BK channel (1)
- BMAC (1)
- BMP4 (1)
- BMSC (1)
- BNC2 (1)
- BNT2b2 (1)
- BOPTA (1)
- BPD (1)
- BPDCN (1)
- BPO (1)
- BPTF (1)
- BRAF V600E (1)
- BRAF inhibitors (1)
- BRAF mutation (1)
- BRD4-NUT (1)
- BRD7 (1)
- BRUCE (1)
- BRVO (1)
- BSP (1)
- BTC (1)
- BTK (1)
- BV6 (1)
- Babesia venatorum (1)
- Baby-Bodyplethysmographie (1)
- Bacillus subtilis (1)
- Back scan (1)
- Backpropagating action potential (1)
- Bacteraemia (1)
- Bacteremia/diagnosis (1)
- Bacteria (1)
- Bacteria-host interaction (1)
- Bacterial abundance (1)
- Bacterial adhesion (1)
- Bacterial intestinal overgrowth (1)
- Bacterial leakage (1)
- Bacterial meningitis (1)
- Bacterial pathogenesis (1)
- Bacterial pathogens (1)
- Bacteriological techniques (1)
- BadA, (1)
- Bag6 (1)
- Bagatelltrauma (1)
- Bakterien (1)
- Bakterientest (1)
- Bakteriologische Techniken (1)
- Bakterizidie Index (1)
- Bakteriämie/Diagnostik (1)
- Balance (1)
- Ballet (1)
- Ballon (1)
- Ballon-assisted enteroscopy (1)
- Balloon-expandable TAVI (1)
- Bamlanivimab (1)
- Bankart-Läsion (1)
- Bariatric surgery (1)
- Barlow disease (1)
- Barrier (1)
- Bartonella (1)
- Bartonella adhesin A (1)
- Bartonella grahamii (1)
- Bartonella schoenbuchensis (1)
- Basal Ganglia (1)
- Basal ganglia (1)
- Basalzellkarzinom (1)
- Basedow-Krankheit (1)
- Basel Consensus Statement (1)
- Basler Consensus Statement (1)
- Bathyergidae (1)
- Batten disease (1)
- Bayesian (1)
- Bayesian inference (1)
- Bayesian model (1)
- Bcl-2 (1)
- Bcr-Abl (1)
- Beatmung (1)
- Beckwith–Wiedemann syndrome (1)
- Becton Dickinson (1)
- Bedburg-Hau, Anstalt (1)
- Bee venom allergy (1)
- Beginners (1)
- Begriffsbestimmung (1)
- Behandlungskontrolle (1)
- Behandlungspfad (1)
- Behandlungssystematik (1)
- Behandlungsumfang (1)
- Behavioral analysis (1)
- Behavioral tests (1)
- Behavioural ecology (1)
- Behinderung (1)
- Bence Jones (BJ) proteinuria (1)
- Bence Jones-Proteinurie (1)
- Benchmarks (1)
- Benign disorder (1)
- Benign enlargement of the subarachnoid spaces (BESS) (1)
- Benign prostatic hyperplasia (1)
- Benign pulmonary diseases (1)
- Benigne Lungenerkrankungen (1)
- Bentall operation (1)
- Beratung (1)
- Berci needle (1)
- Berner, Friedrich (1)
- Berotralstat (1)
- Berufliche Gesundheit (1)
- Berufszufriedenheit (1)
- Beschäftigte (1)
- Besiedelungsgrad (1)
- Best practice (1)
- Best-practice model (1)
- Bestimmungsmethoden (1)
- Bestrahlung (1)
- Betazellfunktion (1)
- Betriebliches Wiedereingliederungsmanagement (1)
- Bevölkerungsschutz (1)
- Bewegungsanalyse mit Inertialsensoren (1)
- Bewegungsstörung (1)
- Bias (1)
- Bibliometric analysis (1)
- Biceps brachii (1)
- Bidirectional genes (1)
- Big data (1)
- Big five (1)
- Bilateral cochlear implant (1)
- Bilateral sagittal split osteotomy (1)
- Bildgebendes Verfahren (1)
- Bildgebung (1)
- Bildqualität (1)
- Bildung (1)
- Bildverarbeitung (1)
- Biliary physiology (1)
- Biliary tree (1)
- Biliary tree stones (1)
- Bilirubin (1)
- Bilirubinbestimmung (1)
- Billroth II gastroenterostomy (1)
- Billroth papillotome (1)
- Billroth’s operation-II (1)
- Binnenmarkt (1)
- Bio safety (1)
- Bioactivity-guided fractionation (1)
- Bioavailability prediction (1)
- Bioelektrische Impedanzanalyse (1)
- Bioenergetics (1)
- Biofluids (1)
- Biological (1)
- Biological Activity (1)
- Biological heart valves (1)
- Biological invasion (1)
- Biological markers (1)
- Biological sciences (1)
- Biologisches Profil (1)
- Biomarker Discovery Study (1)
- Biomarker Lipoprotein(a) (1)
- Biomarker TIMP‑2 und IGFBP7 (1)
- Biomarkers & Diagnostic Imaging (1)
- Biomarkers TIMP‑2 and IGFBP7 (1)
- Biomechanical analysis (1)
- Biophysics (1)
- Bioprosthesis (1)
- Biopterin (1)
- Biotechnology (1)
- Bipolare Störung (1)
- Biposiekomplikationen (1)
- Birth (1)
- Bis-azido-NAD+ Analog (1)
- Bisphosphonates (1)
- Black cohosh (1)
- Black cohosh induced liver injury (1)
- Blasenkarzinom (1)
- Bleeding Risk (1)
- Blended learning curriculum · (1)
- Blended-Learning-Curriculum (1)
- Blended-learning (1)
- Bletilla striata (1)
- Blindness (1)
- Blocked occlusion (1)
- Blood Banks/standards (1)
- Blood Transfusion, Autologous (1)
- Blood cells (1)
- Blood coagulation disorder (1)
- Blood loss calculator (1)
- Blood loss formula (1)
- Blood management (1)
- Blood parameters (1)
- Blood sample handling (1)
- Blood sampling (1)
- Blood transfusion (1)
- Bloodstream infection (1)
- Blot, Western (1)
- Blot, western (1)
- Blow fly (1)
- Blowflies (1)
- BluePrint (1)
- Blurred vision (1)
- Blut- und Plasmaprodukte (1)
- Blutbanken/Standards (1)
- Blutflußumkehr (1)
- Blutgefäß (1)
- Blutgerinnungshemmung (1)
- Blutkulturdiagnostik (1)
- Blutparameter (1)
- Blutspenderscreening (1)
- Bluttransfusion, Autologe (1)
- Blutung (1)
- Blutungskontrolle (1)
- Bochum <2010> (1)
- Body image (1)
- Body limbs (1)
- Body measurements (1)
- Body sway (1)
- Body-contouring surgery (1)
- Bodyplethysmographie (1)
- Bologna process (1)
- Bologna-Prozess (1)
- Bone and joint mechanics (1)
- Bone cancer (1)
- Bone cement implantation syndrome (1)
- Bone conduction devices (1)
- Bone diseases, Metabolic (1)
- Bone dust (1)
- Bone marrow aspirate concentrate (1)
- Bone marrow cells (1)
- Bone marrow fibrosis (1)
- Bone marrow mononuclear cells (1)
- Bone metastasis (1)
- Bone remodelling (1)
- Bone strength assessment (1)
- Bone substitute (1)
- Bone tumor (1)
- Borrelia Garinii (1)
- Borrelia miyamotoi (1)
- Bortezomib (1)
- Bottom-up (1)
- Bovine Spongiforme Enzephalopathie (BSE) (1)
- Bovine spongiform, encephalopathy (BSE) (1)
- Brachial artery (1)
- Brachytherapy (1)
- Bradycardia (1)
- Bradykinin (1)
- Brain DNA methylation (1)
- Brain anatomy (1)
- Brain asymmetry (1)
- Brain damage (1)
- Brain development (1)
- Brain injuries (1)
- Brain injury (1)
- Brain ischemia (1)
- Brain repair (1)
- Brain tumor surgery (1)
- Brain tumors (1)
- BrainNet Europe consortium (1)
- Breast Cancer (1)
- Breast cancer survivers (1)
- Breast conserving surgery (1)
- Breast neoplasm (1)
- Breast reconstruction (1)
- Breath testing (1)
- Breathing (1)
- Breech delivery (1)
- Bright light therapy (1)
- Brij 35 (1)
- BrijL23 (1)
- Brms (1)
- Brodalumab (1)
- Bronchial challenge (1)
- Bronchial inflammation (1)
- Bronchiale Hyperreagibilität (1)
- Bronchialkrebs (1)
- Bronchiolitis (1)
- Bronchiolitis obliterans (1)
- Bronchitis severity scale (1)
- Broncho-alveoläre Lavage (1)
- Bronchodilator agents (1)
- Bronchopulmonary dysplasia (1)
- Browsertool (1)
- Brustkrebs ; Klinische Medizin ; Kontrollierte klinische Studie (1)
- Bufonidae (1)
- Bundesärztekammer / Ausschuss Arbeitsmedizin (1)
- Bungarus niger (1)
- Bupivacain (1)
- Bupivacaine (1)
- Burkholderia arboris (1)
- Burkitt’s lymphoma (1)
- Burns (1)
- Burst (1)
- Bypass liner (1)
- Bühnentanz (1)
- Büroangestellte (1)
- Büroarbeit (1)
- C-clamp (1)
- C-reactive proteins (1)
- C-reaktive protein (1)
- C-reäktives Protein (1)
- C1 esterase inhibitor (human) (1)
- C1-INH (C1 inhibitor, C1-esterase inhibitor) (1)
- C1-esterase inhibitor protein (1)
- C1-inhibitor (1)
- C1-inhibitor deficiency (1)
- C2 domain (1)
- C3M (1)
- C4M (1)
- C5 acylcarnitine (1)
- C57BL/6J mice (1)
- C57BL/6N mice (1)
- C6 ceramide (1)
- CA (1)
- CA1 (1)
- CAD-CAM (1)
- CAD/ CAM crown (1)
- CAD/CAM crown (1)
- CAKUT (1)
- CAPON (1)
- CAR-NK cell (1)
- CAR-T cell (1)
- CAT (1)
- CBC (1)
- CBCT (1)
- CCC-2 (1)
- CCN2 (1)
- CD107-Assay (1)
- CD137 (1)
- CD23 (1)
- CD271 (1)
- CD3 (1)
- CD3/19 depletion (1)
- CD3/CD19 depletion (1)
- CD34 (1)
- CD34 selection (1)
- CD34+ cell enumeration (1)
- CD34 + cells (1)
- CD4 binding site (1)
- CD4+ T cells (1)
- CD40 (1)
- CD41 (1)
- CD45RA Depletion (1)
- CD45RA naïve lymphocytes (1)
- CD47 (1)
- CD49d (1)
- CD56 (1)
- CD62L (1)
- CD62P (1)
- CD62p+Exosomes (1)
- CD74 (1)
- CD8 (1)
- CD8+ T cell (1)
- CD8+ T cells (1)
- CD8+ T lymphocytes (1)
- CD8+ T-cell mediated tumor suppression (1)
- CD8+ tumor infiltrating lymphocytes (1)
- CD8+ zytotoxische T-Zellen (1)
- CD95/Fas receptor (1)
- CDH13 (1)
- CDI (1)
- CDK inhibitor (1)
- CDK-cyclin axis (1)
- CDK2 (1)
- CDK4/6 inhibitor (1)
- CDK4/6 inhibitors (1)
- CDK4/CDK6 (1)
- CDKN2A (1)
- CE (1)
- CE marking (1)
- CE-Kennzeichnung (1)
- CEBPD (1)
- CEBPE (1)
- CEST EPI (1)
- CGD (1)
- CGN codon (1)
- CHA2DS2-VASc-score (1)
- CHAID-Analyse (1)
- CHAID-Analysis (1)
- CHEPs (1)
- CHIP (1)
- CHRDL1 (1)
- CHRNA10 (1)
- CHRNA7 (1)
- CHRNA9 (1)
- CIK cell (1)
- CIM (1)
- CK2α (1)
- CLEC-2 (1)
- CLIF-C ACLF score (1)
- CLIF-C ACLF-R score (1)
- CLOCC (1)
- CLS (1)
- CMR (1)
- CMS (1)
- CMV isolation (1)
- CMV risk groups are: pregnancy - blood transfusion - organ transplantation - prostitutes (1)
- CMV-Isolierung (1)
- CMVepidemiology (1)
- CNDAC (1)
- CNS (1)
- CNS cancer (1)
- CNS toxicity (1)
- CNS tumor (1)
- CNV (1)
- CNVs (1)
- CO2-induced forced ventilation (1)
- COBAS Taqman (1)
- COI (1)
- COII (1)
- COMT (1)
- COPD course and therapy (1)
- COVID (1)
- COVID 19 pandemic (1)
- COVID-19 epitope signatures (1)
- COVID-19 pandemic (1)
- COVID-19 vaccination (1)
- COVID-19, Primary care (1)
- COVID‐19 (1)
- CPET (1)
- CPT1A (1)
- CQL (1)
- CRBN (1)
- CRE-dependent transcription (1)
- CRE-luciferase (1)
- CREB inhibitor (1)
- CRISPR screen (1)
- CRISPR/dCas9 (1)
- CRM1 (1)
- CRPC (1)
- CRT (1)
- CRT-D (1)
- CRVO (1)
- CSC marker (1)
- CT dual-energy computed tomography (1)
- CT pulmonary angiography (1)
- CT radiation exposure (1)
- CT-guidance (1)
- CT-guided interventions (1)
- CTC (1)
- CTX (1)
- CTX and NTX (1)
- CTX und NTX (1)
- CUELA system (1)
- CUP (1)
- CVD biomarker (1)
- CVID (1)
- CWS Studiengruppe (1)
- CX-2 (1)
- CXCL10 (1)
- CXCL13 (1)
- CXCL16 (1)
- CXCR3 antagonism (1)
- CY-503 (1)
- CYBA/p22phox (1)
- CYP1A1 (1)
- CYP450 (1)
- Ca2+ imaging (1)
- CaMPARI (1)
- Cabozantinib (1)
- Caco 2 cells/metabolism (1)
- Caco-2 cells (1)
- Caco‐2 cells (1)
- Caenorhabditis elegans (1)
- Caffeine (1)
- Calcium calmodulin kinase (1)
- Calcium gluconate (1)
- Calcium signalling (1)
- Calciumphosphatprodukt (1)
- Calnexin (1)
- Canada (1)
- Cancer Staging (1)
- Cancer check up (1)
- Cancer detection (1)
- Cancer development (1)
- Cancer epigenetics (1)
- Cancer of unknown primary (1)
- Cancer progression (1)
- Cancer risk factors (1)
- Cancer staging (1)
- Cancer stem cells (1)
- Cancer survivors (1)
- Cancer therapeutic resistance (1)
- Cancer-specific survival (1)
- Candida spp (1)
- Cannabis-based Medicine (1)
- Capacity deficit (1)
- Capillary-Leak-Syndrom (1)
- Capnography (1)
- Capsaicin (1)
- Capsule endoscopy, video (1)
- Carbapenem-resistente Gram-negative Bakterien (CRGN) (1)
- Carbapenemasen (1)
- Carbohydrates (1)
- Carbon tetrachloride (1)
- Carcinogenese (1)
- Carcinoma (1)
- Carcinoma, Ductal, Breast (1)
- Cardiac (1)
- Cardiac Fibrosis (1)
- Cardiac acoustic biomarkers (1)
- Cardiac biomarkers (1)
- Cardiac device therapy (1)
- Cardiac fibroblast (1)
- Cardiac function (1)
- Cardiac implantable electronic devices (1)
- Cardiac infarction (1)
- Cardiac masses (1)
- Cardiac monitoring (1)
- Cardiac necroenzymes (1)
- Cardiac output (1)
- Cardiac rehabilitation (1)
- Cardiac remodeling (1)
- Cardiac remodelling (1)
- Cardiac resynchronization therapy (1)
- Cardiac surgery patients (1)
- Cardiac troponin (1)
- Cardiavascular function (1)
- Cardio-oncology (1)
- CardioMEMS™ HF system (1)
- Cardiogenic shock (1)
- Cardiomyocyte signaling pathways (1)
- Cardiomyopathy (1)
- Cardiopulmonary bypass (1)
- Cardiotoxicity (1)
- Cardiovascular Magnetic Resonance (CMR) (1)
- Cardiovascular disease risk (1)
- Cardiovascular epidemiology (1)
- Cardiovascular genetics (1)
- Cardiovascular mortality (1)
- Cardiovaskuläre Erkrankungen (1)
- Care centers (1)
- Care gaps (1)
- Care home (1)
- Career promotion (1)
- Careers (1)
- Carotid injury (1)
- Carotid stenosis (1)
- Carrier-bound fibrin sealant (1)
- Cartilage (1)
- Cartilage Biology (1)
- Cas9 inhibitor (1)
- Case management [MeSH] (1)
- Casirivimab (1)
- Caspase-8 (1)
- Caspasen (1)
- Castleman’s disease (1)
- Catch-up validation study (1)
- Catel, Werner (1)
- Catheters (1)
- Catumaxomab (1)
- Causality (1)
- Causality assessment. (1)
- Cause of death (1)
- Cdk1/cyclin B1 (1)
- Cell Adhesion (1)
- Cell Biology (1)
- Cell Death (1)
- Cell Metabolism (1)
- Cell Migration (1)
- Cell Signaling (1)
- Cell Surface Receptor (1)
- Cell adhesion (1)
- Cell cortex (1)
- Cell cultures (1)
- Cell cycle (1)
- Cell distribution (1)
- Cell membranes (1)
- Cell metabolism (1)
- Cell motility (1)
- Cell plasticity (1)
- Cell processing (1)
- Cell surface proteoglycans (1)
- Cell-assisted lipotransfer (1)
- Cell-based Assays (1)
- Cell-based therapies (1)
- Cell-to-Cell Spread (1)
- Cellular (1)
- Cellular Immune Response (1)
- Cellular energy metabolism (1)
- Cellular imaging (1)
- Cellular inflammatory response (1)
- Cellular network formation (1)
- Cellular neuroscience (1)
- Cellular stress (1)
- Cellular stress responses (1)
- Cement gap (1)
- Cementation (1)
- Center-specific time in therapeutic range (cTTR) (1)
- Centers for Disease Control and Prevention (1)
- Central Europe (1)
- Central nervous system (1)
- Central nervous system metastases (1)
- Centrifugation (1)
- Cephalometry via electromagnetic induction (1)
- Cephalometry without x-rays (1)
- Ceramic (1)
- Ceramides (1)
- Cerasorb (1)
- Cerclage (1)
- Cerebellar ataxia (1)
- Cerebral Vasospasm (1)
- Cerebral cortex (1)
- Cerebral hypoperfusion (1)
- Cerebral ischemia (1)
- Cerebral oxygen saturation (1)
- Cerebral toxoplasmosis HIV (1)
- Cerebral vasospasm (1)
- Cerebrospinal Fluid (1)
- Cerebrospinal fluid diagnostics (1)
- Cerebrovascular (1)
- Cerebrovascular disorders (1)
- Certification (1)
- Cervical (1)
- Cesarean delivery (1)
- Cethromycin (1)
- Cezanne (1)
- ChAdOx1-S (1)
- Change Management (1)
- Checkliste (1)
- Checkpoint Inhibitor (1)
- Checkpoint kinase (1)
- Checkpoints (1)
- Chemical company (1)
- Chemical ecology (1)
- Chemical labeling (1)
- Chemical modification (1)
- Chemiluminescence (1)
- Chemobrain (1)
- Chemoembolization (1)
- Chemokine CCL2 (1)
- Chemoradiation (1)
- Chemorefractory advanced gastric cancer (1)
- Chemosensitivity (1)
- Chemotherapie (1)
- Chest pain unit (1)
- Chikungunya (1)
- Chikungunya virus (1)
- Child abuse (1)
- Child adiposity (1)
- Child and adolescent psychotherapy (1)
- Chimeric Antigen Receptor (CAR) (1)
- Chimerism (1)
- Chimiothérapie (1)
- Chinesischer Rhabarber (1)
- Chlamydia-Infections/urine (1)
- Chlamydien (1)
- Chlamydieninfektionen/Urin (1)
- Chloralhydrat (1)
- Chlorides (1)
- Chloroform (1)
- Chloroquin (1)
- Cholecystectomy (1)
- Cholesterin (1)
- Cholesterinveresterung (1)
- Cholesterol (1)
- Cholinergic (1)
- Chondral Lesion (1)
- Chondrocyte (1)
- Chondrocyte signalling (1)
- Chorion (1)
- Chrna7 knockout (1)
- Chrom (1)
- Chromatin and Epigenetics (1)
- Chromatin conformation (1)
- Chromodomains (1)
- Chromoendoscopy (1)
- Chromosom (1)
- Chromosomal deletion (1)
- Chromosomale Translokation (1)
- Chronic Hepatitis C (1)
- Chronic ankle instability (1)
- Chronic care model (1)
- Chronic conditions (1)
- Chronic depression (1)
- Chronic disease [MeSH] (1)
- Chronic health condition (1)
- Chronic heart failure (1)
- Chronic hepatitis C virus (1)
- Chronic illness (1)
- Chronic infection (1)
- Chronic intestinal failure (1)
- Chronic lymphocytic leukemia (1)
- Chronic medical conditions (1)
- Chronic obstructive airway disease (1)
- Chronic pancreatitis (1)
- Chronic periodontiti (1)
- Chronification (1)
- Chronisch aktive/Diagnostik (1)
- Chronisch-venöse Insuffizienz (1)
- Chronische Fehl- und Überlastungsschäden (1)
- Chronische Krankheit (1)
- Chronische Niereninsuffizienz (1)
- Chronischer Schmerz (1)
- Chronology of disease (1)
- Cigarette (1)
- Cigarettes (1)
- Cine (1)
- Cinnarizine (1)
- Cinryze® (1)
- Ciprofloxacin (1)
- Circadian (1)
- Circadian rhythms and sleep (1)
- Circulating MiRNA (1)
- Circulating markers (1)
- Circulation (1)
- Cirugía (1)
- Cisplatinresistenz (1)
- Citation (1)
- Citationrate (1)
- Cities (1)
- Citrat (1)
- Civil protection (1)
- Claudin 5 (1)
- Clavien–Dindo classification (1)
- Cleanliness level (1)
- Cleft palate (1)
- Click chemistry (1)
- Climate inequity (1)
- Clincial pharmacology (1)
- CliniMACS (1)
- Clinical Skills (1)
- Clinical effectiveness (1)
- Clinical efficacy (1)
- Clinical frailty scale (1)
- Clinical management (1)
- Clinical outcome (1)
- Clinical pathway (1)
- Clinical pathways (1)
- Clinical pharmacology (1)
- Clinical phenotype (1)
- Clinical practice guidelines (1)
- Clinical psychometry (1)
- Clinical skills (1)
- Clinical variation (1)
- Clip (1)
- Cln3 (1)
- Clonidin (1)
- Clonidine (1)
- Clopidogrel (1)
- Clostridioides difficile (1)
- Clostridium (1)
- Closure (1)
- ClpB (1)
- Cluster (1)
- Cluster randomization (1)
- Clustering (1)
- Co-culture (1)
- Co-morbidity (1)
- Coagulation (1)
- Coagulopathy management (1)
- Cochlear Implant (1)
- Codierung (1)
- Coenzyme Analogue (1)
- Coenzyme Binding (1)
- Coeval folding and boudinage (1)
- Coexistence (1)
- Cofilin (1)
- Cognitive (1)
- Cognitive behavioural therapy (1)
- Cognitive dysfunction (1)
- Cognitive enhancers of exposure therapy (1)
- Cognitive neurology (1)
- Cognitive psychology (1)
- Coherent infomax (1)
- Cohort Analysis (1)
- Cohort study (1)
- Colchicum (1)
- Cold hardiness (1)
- Cold pain (1)
- Cold tolerance (1)
- Colitis Ulcerosa (1)
- Collagen antibody-induced arthritis (1)
- Collagen hemostat (1)
- Collagen type I (1)
- Collagen type III (1)
- Collagen-based biomaterial (1)
- Collagens (1)
- Colon cancer (1)
- Colon capsule endoscopy (1)
- Colonic neoplasms (1)
- Colonisation (1)
- Colonkrebs (1)
- Colony stimulating factor 1 receptor (1)
- Colorimetric blood loss estimation (1)
- Combined immune checkpoint blockade (1)
- Combined surgical therapy (1)
- Combo® DTS (1)
- Combustion (1)
- Commercial Immunoglobulins (1)
- Communicable diseases (1)
- Comparative effectiveness research (1)
- Comparative study (1)
- Comparators (1)
- Compartmental modeling (1)
- Competencies (1)
- Complement Regulator (1)
- Complement cascade (1)
- Complement system (1)
- Complementary medicine (1)
- Complementation rate (1)
- Complete heart block (1)
- Complete response (1)
- Completed suicide (1)
- Complex II (1)
- Complex Systems (1)
- Complex decongestive therapy (1)
- Complex elbow fractures (1)
- Complex hernia (1)
- Complex networks (1)
- Complexin 1 (1)
- Complexin-1 (1)
- Complexome profiling (1)
- Compliance-Beobachtung (1)
- Complicated stage (1)
- Complication (1)
- Comprehensive cancer centers (1)
- Comprehensive complication index (1)
- Compression stocking (1)
- Computational biology and bioinformatics (1)
- Computational biophysics (1)
- Computational model (1)
- Computational neuroscience (1)
- Computational sRNA analysis (1)
- Computational science (1)
- Computed Tomography (1)
- Computed axial tomography (1)
- Computed tomography imaging (1)
- Computed tomography pulmonary angiography (CTPA) (1)
- Computed tomography, X-ray (1)
- Computer simulation (1)
- Computer-Assisted (1)
- Computer-aided drug design (1)
- Computer-unterstützte (1)
- Computers (1)
- Concept paper (1)
- Conception (1)
- Concurrent CNS diseases (1)
- Concurrent chemoradiotherapy (1)
- Conditional gene trap (1)
- Conduct problems (1)
- Conduit function (1)
- Cone-beam computed tomography (1)
- Confinement (1)
- Confocal endomicroscopy (1)
- Conformational change (1)
- Congenital (1)
- Congenital CMVinfection (1)
- Congenital anomalies (1)
- Congenital diaphragmatic hernia (1)
- Congenital duodenal obstruction (1)
- Congenital ocular motor apraxia (1)
- Coniosporium corticale (1)
- Connectivity (1)
- Connectomics (1)
- Conometric connection (1)
- Consciousness (1)
- Consensus document (1)
- Consensus methods (1)
- Consensus statement (1)
- Conservative (1)
- Conservative treatment (1)
- Consortia (1)
- Constipation (1)
- Constitution (1)
- Constrained posture (1)
- Constriction (1)
- Contact precautions (1)
- Contingent Negative Variation, CNV (1)
- Continuous Performance Test, CPT (1)
- Continuous renal replacement therapy (1)
- Contraceptifs hormonaux (1)
- Contractile function (1)
- Contrast agent (1)
- Contrast-Enhancing Lesions (1)
- Contrast-enhanced (1)
- Control (1)
- Conventional Chemotherapeutic (1)
- Conventional and unconventional ubiquitination (1)
- Conventional dendritic cells (1)
- Conventional synthetic disease-modifying antirheumatic drug (1)
- Convolutional Neural Networks (1)
- Cooperation (1)
- Coping (1)
- Copy number (1)
- Copy number variation (1)
- Cord blood transplantation (1)
- Cordichin (1)
- Core needle biopsy (1)
- Cornea (1)
- Corneal tomography (1)
- Corona pandemic (1)
- Corona virus (1)
- Coronary artery disease (CAD) (1)
- Coronary intervention (1)
- Coronaviren (1)
- Coronaviruses (1)
- Cortical degeneration (1)
- Cortical thickness (1)
- Corticotropic axis (1)
- Cost-effectiveness analysis (1)
- Couch tracking (1)
- Council for International Organizations of Medical Sciences (1)
- Course (1)
- Course evaluation (1)
- Cox-2-Inhibitoren (1)
- Cox-Regression (1)
- CoxVa (1)
- Coxibs (1)
- Coxsackieviren (1)
- Craniomandibular disorders (1)
- Craniomaxillofacial injuries (1)
- Cre-recombinase (1)
- Creatinine (1)
- Credentialing (1)
- Creeping Disease (1)
- Crisis (1)
- Crispr/Cas (1)
- Critical Online Reasoning Assessment (1)
- Critical bleeding (1)
- Critical care and emergency medicine (1)
- Critical haematocrit (1)
- Critical pathway (1)
- Critical size (1)
- Cross- sectional study (1)
- Cross-contamination (1)
- Cross-frequency coupling (1)
- Cross-sectional (1)
- Cross-sectional study (1)
- Crosscorrelation (1)
- Crossmodal (1)
- Cryo-electron microscopy (1)
- Cryoablation (1)
- Cryoballoon (1)
- Cryptococcus (1)
- Cryptostroma corticale (1)
- CspA (1)
- Cue-P3 (1)
- Culex pipiens (1)
- Culex pipiens biotypes pipiens/molestus (1)
- Culicidae (1)
- Culture positive (1)
- Cumulative dose (1)
- Curcumis sativus (1)
- Cure (1)
- Curvilinear dose response (1)
- Cushing-Syndrom (1)
- Cushing’s syndrome (1)
- Custom-made mouthguard (1)
- Cyanoacrylate (1)
- CyberKnife (1)
- Cyclin T1 (1)
- Cyclooxygenase (1)
- Cyclosporin A (1)
- Cyp46a1 (1)
- Cystatin C (1)
- Cysteine‐Rich Domain (CRD) (1)
- Cytochrome P450 (1)
- Cytochrome P450 enzymes (1)
- Cytokines Induction (1)
- Cytology (1)
- Cytomegalie (1)
- Cytomegalie-Virus (1)
- Cytomegalovirus (1)
- Cytomegalovirus (CMV) (1)
- Cytomegalovirus Infection (1)
- Cytoplasm (1)
- Cytoplasmic staining (1)
- Cytotoxic CD8+ T cell (1)
- Cytotoxicity (1)
- C‐reactive protein (1)
- D-amino acid oxidase (1)
- D-dimer (1)
- D2-autoreceptor (1)
- DAMP (1)
- DAMPs (1)
- DAN-G (1)
- DBH genotype (1)
- DBS (1)
- DC-NK cell interaction (1)
- DCK (1)
- DCM (1)
- DDA (1)
- DDIT4 (1)
- DEE (1)
- DEPDC5 (1)
- DFNB9 (1)
- DHA (1)
- DILI database case quality (1)
- DIN EN ISO 15189 (1)
- DJ-Katheter (1)
- DKK1 (1)
- DKTK-ROG (1)
- DLBCL (1)
- DMARDs (synthetic) (1)
- DME (1)
- DMXAA (1)
- DNA Adducts (1)
- DNA Damage (1)
- DNA double-strand break repair (1)
- DNA integrity (1)
- DNA repair (1)
- DNA replication (1)
- DNA sequence analysis (1)
- DNA sequencing (1)
- DNA, Virale/Blut (1)
- DNA-Methylierung (1)
- DNA-PK (1)
- DNA-based identification (1)
- DNA-binding proteins (1)
- DNA-protein crosslinks (1)
- DOK1 (1)
- DOT1L (1)
- DPPIV (1)
- DR5 (1)
- DRG (1)
- DRIL-Procedur (1)
- DRIL-procedure (1)
- DSAEK (1)
- DSS /AOM (1)
- DST (1)
- DTHR (1)
- DUBs (1)
- DVI (1)
- DVT (1)
- DWI (1)
- DYRK1A (1)
- DYT1 (1)
- Dabigatran (1)
- Dance (1)
- Dancer (1)
- Dark triad (1)
- Darmerkrankung (1)
- Darreichungsform (1)
- Darunavir (1)
- Data Analysis (1)
- Data acquisition (1)
- Data mining (1)
- Data monitoring (1)
- Data preprocessing (1)
- Data protection (1)
- Data reduction (1)
- Data structure detection (1)
- Data validation (1)
- Database (1)
- Database searching (1)
- Databases (1)
- Dataset bias (1)
- Datenqualität (1)
- Datenschutz (1)
- Datenverarbeitung (1)
- Daubert criteria (1)
- Dauerversorgung (1)
- David technique (1)
- De-isolation (1)
- Dead space (1)
- Death certificate (1)
- Decay (1)
- Decision Confidence (1)
- Decision impact (1)
- Decision support (1)
- Decision-making (1)
- Decolonization (1)
- Decontamination (1)
- Deep learning (1)
- Deep neural network (1)
- Deep vein thrombosis (1)
- Deficient Inhibition (1)
- Deformation (1)
- Deformation oblique layer (1)
- Degrader design (1)
- Dehnen (1)
- Dehntraining (1)
- Dehydrogenase (1)
- Delayed Cerebral Ischemia (1)
- Delayed union (1)
- Deletion mutation (1)
- Delivery mode (1)
- Delivery quality assurance (1)
- Delphi Survey (1)
- Delphie-Befragung (1)
- Demenz (1)
- Dendritic Cells (1)
- Dendritic cell (1)
- Dendritic cell population (1)
- Dendritic cells (1)
- Dendritic spines (1)
- Dendritische Zelle (1)
- Denervation (1)
- Dengue fever (1)
- Dengue fever virus (1)
- Dengue virus (1)
- Denguefieber (1)
- Density equalizing (1)
- Dental Tissues (1)
- Dental air (1)
- Dental assistants (1)
- Dental casts (1)
- Dental education (1)
- Dental phobia (1)
- Dental practice (1)
- Dental training (1)
- Dentale Implantate (1)
- Dentalkeramik; Grünling <Technik>; CAM; Hartmetallwerkzeug; Werkzeugverschleiß; Dimensionsstabilität; Schleifwerkzeug; Diamantwerkzeug (1)
- Dentin adhesives (1)
- Dentition (1)
- Depolarization (1)
- Depression stigma (1)
- Dermal fat (1)
- Dermatitis (1)
- Dermatomyositis (1)
- Desinfektion von Flugzeugen (1)
- Desmin (1)
- Detection (1)
- Detection workflow (1)
- Determination method (1)
- Detraining (1)
- Deutsche Gesellschaft für Arbeitsmedizin (1)
- Deutsche Gesellschaft für Chirurgie (1)
- Deutscher Gewerkschaftsbund (1)
- Deutsches Rotes Kreuz (1)
- Deutschland / Bundesministerium für Gesundheit (1)
- Deutschland / Fallpauschalengesetz (1)
- Developmental Biology (1)
- Developmental disorders (1)
- Developmental programming (1)
- Developmental trajectory (1)
- Developmentally adapted cognitive processing therapy (1)
- Devic disease (1)
- Devic syndrome (1)
- Device (1)
- Dexamethasone (1)
- Dexterity (1)
- Diabetes mellitus Typ 1 und Typ 2 (1)
- Diabetes mellitus Typ 2 (1)
- Diabetic nephropathy (1)
- Diagnosen ICD-10 Ziffern G41.0, G41.1, G41.2, G41.8, G41.9 (1)
- Diagnosenschlüssel (1)
- Diagnoses ICD-10 codes G41.0, G41.1, G41.2, G41.8, G41.9 (1)
- Diagnosis related groups (1)
- Diagnostic differentiation (1)
- Diagnostic dye (1)
- Diagnostic error (1)
- Diagnostic imaging (1)
- Diagnostic techniques and procedures (1)
- Diagnostic tests (1)
- Diagnostik von MLL Translokationen (1)
- Dialog-Konsens- Methoden (1)
- Dialyse-assoziiertes Steal-Syndrom (1)
- Dialysis-associated Steal Syndrome (1)
- Diary Data (1)
- Diastolische Dysfunktion (1)
- Dicer (1)
- Dichloromethane (1)
- Dichtebestimmung (1)
- Dickdarmkrebs (1)
- Didaktik (1)
- Diesel (1)
- Diet (1)
- Dietary HDAC inhibitor (1)
- Dietary intake (1)
- Dietary supplements (1)
- Dieulafoy’s lesion (1)
- Differential Thermoanalysis (1)
- Differential expression (1)
- Difficult Airway Management (1)
- Diffuse astrocytoma (1)
- Diffuse large B cell lymphoma (1)
- Diffusion (1)
- Diffusion Tensor Imaging (1)
- Diffusion magnetic resonance imaging (1)
- Diffusion of Innovations (1)
- Diffusion-Weighted Imaging (1)
- Diffusions-Tensor-Bildgebung (1)
- Diffusionsbildgebung (1)
- Digenic model (1)
- Digestive system (1)
- Digital (1)
- Digital breast tomosynthesis (DBT) (1)
- Digital ethics (1)
- Digital hybrid visualization (1)
- Digital mammography (1)
- Digital pathology (1)
- Digital rectal examination (1)
- Digital subtraction angiography (1)
- Digital transformation (1)
- Digital workshops (1)
- Digitale Ethik (1)
- Digitale Transformation (1)
- Digitale Volumen Tomographie (1)
- Digitization (1)
- Dilated cardiomyopathy (1)
- Dimer (1)
- Dimers (Chemical physics) (1)
- Dimethyltryptamine (1)
- Dipeptide (1)
- Diphosphonates (1)
- Diphtheria (1)
- Diptera (1)
- Direct Acting Antivirals (DAA) (1)
- Direct acting antiviral therapies (1)
- Direct measurement (1)
- Direct oral anticoagulation (1)
- Direct-acting antiviral agents (DAAs) (1)
- Direct-acting antivirals (1)
- Disabilities (1)
- Disabling back pain (1)
- Disaster victim identification (1)
- Disc herniation (1)
- Discitis (1)
- Disconnection (1)
- Discovery (1)
- Discs large (1)
- Disease burden (1)
- Disease management (1)
- Disease progression (1)
- Disinfection of aircraft (1)
- Diskonnektion (1)
- Dislocations of the knee (1)
- Dissemination (1)
- Dissociative seizures (1)
- Distale Revascularisation- Intervall Ligatur (1)
- Distance learning (1)
- Distanzunterricht (1)
- Distress (1)
- Distress screening (1)
- Distribution (1)
- Distribution limits (1)
- Dizygotic ectopic (1)
- Dog (1)
- Dogs (1)
- Dome-and-basin structure (1)
- Domestic (1)
- Donor Selection (1)
- Donor screening (1)
- Doppler-Sonographie (1)
- Dorsal root ganglia (1)
- Dorsolateral prefrontal cortex (1)
- Dose optimization (1)
- Dosiskonzepte (1)
- Dot-probe task (1)
- Double balloon enteroscopy (1)
- Double suicide (1)
- Double-blind placebo-controlled trial (1)
- Doubling time (1)
- Douleur (1)
- Down's syndrome (1)
- Downgrading (1)
- Doxorubicin (1)
- Doxycyclin (1)
- Dravet (1)
- Drogenabhängigkeit (1)
- Drogentherapie (1)
- Drogentote (1)
- Droplets (1)
- Drospirenon (1)
- Drug (1)
- Drug Discovery (1)
- Drug Therapy (1)
- Drug addiction (1)
- Drug discovery (1)
- Drug interactions (1)
- Drug permeability (1)
- Drug resistance/synergy (1)
- Drug screens (1)
- Drug susceptibility testing (1)
- Drug targeting (1)
- Drug targets (1)
- Dual energy CT (1)
- Dual therapy (1)
- Dual-Source CT (1)
- Dual-energy computed tomography (1)
- Duchenne’s muscular dystrophy (1)
- Dumon stents (1)
- Duodenal atresia (1)
- Duodenal stenosis (1)
- Duodenum (1)
- Dural onlays (1)
- Durchblutungsstörung (1)
- Durchseuchung (1)
- Dvc1 (1)
- Dysfibrinogenämia (1)
- Dysfunctional social assumptions (1)
- Dyslexia (1)
- Dysphagia (1)
- Désir d’enfant (1)
- D’Amico classification (1)
- E protein structure (1)
- E-cadherin (1)
- E-cadhérine (1)
- E-health (1)
- E-learning (1)
- E. coli (1)
- E/I-Balance (1)
- E3-Ligases (1)
- EAA (1)
- EASI (1)
- EBRA-FCA (1)
- EBRT (1)
- ECLS (1)
- ECM (1)
- EDB (1)
- EDTA-plasma (1)
- EEG reference choices (1)
- EFP1 (1)
- EFRS (1)
- EGF (1)
- EGFL7 (1)
- EGFP (1)
- EGFR inhibitor (1)
- EGFR pathway (1)
- EGFRvIII mutation (1)
- EGR1-dependent transcription (1)
- EHL concentrates (1)
- EIIIB (1)
- ELISPOT (1)
- ELSID-Diabetes (1)
- EMD 55900 (1)
- EMD 72000 (1)
- EMR1 (1)
- EN ISO 15189 (1)
- ENIGMA (1)
- EOB (1)
- EP300 (1)
- EPA (1)
- EQ (1)
- EQ5D5L (1)
- EQA scheme (1)
- EQIP (1)
- ER-phagy (1)
- ERAL1 (1)
- ERBB2 (1)
- ERBB2 (HER2/neu) (1)
- ERCP (1)
- ERK inhibitor (1)
- ERK1/2 signaling (1)
- ERK3/MAPK6 (1)
- ERM (1)
- ERMS (1)
- ERSCongress (1)
- ES (1)
- ES cells (1)
- ESMO-MCBS (1)
- ESR Spectroscopy (1)
- ESR and Infrared Studies (1)
- ESWT (1)
- ET (1)
- ETP-ALL (1)
- ETS (1)
- EWS/Fli1 (1)
- EZ-IO® needle driver (1)
- Early (prenatal and postnatal) life experiences (1)
- Early Rheumatoid Arthritis (1)
- Early diagnosis (1)
- Early goal-directed therapy (1)
- Early intervention (1)
- Early recurrence (1)
- Early setting (1)
- Ebola (1)
- Ebola virus (1)
- Echocardiography (1)
- Echovirus-30 (1)
- Eclampsia (1)
- Ecological Momentary Assessment (EMA) (1)
- Ecological momentary assessment (1)
- Economic analysis (1)
- Economic benchmarks (1)
- Economic evaluation (1)
- Economic impact (1)
- Economics (1)
- Ectopic bone formation (1)
- Ectopic pregnancy (1)
- Ectopic varices (1)
- Edentulous jaw (1)
- Edinger, Ludwig (Arzt) (1)
- Educación médica (1)
- Efavirenz (1)
- Effective connectivity (1)
- Effective half-life (1)
- Effectivity (1)
- Eicosanoide (1)
- Eicosanoids (1)
- Eignungsprüfung (1)
- Einfachauswahlverfahren (1)
- Einflussnahme (1)
- Eingangstest (1)
- Einmaleinnahme (1)
- Einreibetechnik (1)
- Einstellungen zu Impfungen (1)
- Einwilligungsfähigkeit (1)
- Einzelzahnimplantate (1)
- Eisenbestimmung (1)
- Eisenmangel (1)
- Eisenstoffwechsel (1)
- Ektachem® (1)
- Elastogenesis (1)
- Elastographie (1)
- Elderly patients (1)
- Elderly trauma patient (1)
- Elective caesarean section (1)
- Electric stimulation (1)
- Electrical accident (1)
- Electrical instability (1)
- Electroconvulsive Therapy (1)
- Electroencephalography – EEG (1)
- Electrolytes (1)
- Electron transport chain (1)
- Electronic cigarettes (1)
- Electrotonic analysis (1)
- Elektrischer Sturm (1)
- Elektroencephalographie (1)
- Elektroenzephalographie (1)
- Elektronenmikroskopie (1)
- Elektrophysilogie (1)
- Elimination (1)
- Elite football (1)
- Ellipsoids (1)
- Ellipticine (1)
- Elternurteil (1)
- Embden, Gustav (1)
- Embolie (1)
- Embolization (1)
- Embryos (1)
- Emergency (1)
- Emergency card (1)
- Emergency care (1)
- Emergency medicine (1)
- Emergency treatment (1)
- Emotion (1)
- Emotion processing (1)
- Emotional intelligence (1)
- Emotional recognition (1)
- Empfehlungen (1)
- Empfindlichkeitstestung (1)
- Emphysema (1)
- Employment (1)
- Employment effect (1)
- Ena/VASP proteins (1)
- Encephalitis Viruses (1)
- End-of-life decisions (1)
- Endocrine cancer (1)
- Endocrine system and metabolic diseases (1)
- Endocrine therapy (1)
- Endodontie (1)
- Endogenous retroviruses (ERV) (1)
- Endoluminal (1)
- Endometrial cancer (1)
- Endometrial carcinoma (1)
- Endometriome (1)
- Endometriose (1)
- Endometriosis (1)
- Endomicroscopy (1)
- Endométriomes (1)
- Endoplasmic reticulum (1)
- Endorectal (1)
- Endoscopic coronary revascularisation (1)
- Endoscopic papillotomy (1)
- Endoscopic retrograde Cholangiopancreatography (ERCP) (1)
- Endoscopic retrograde cholangiography (1)
- Endoscopic sphincterotomy (1)
- Endoscopic treatment (1)
- Endoskopie (1)
- Endoskopik koroner revaskülarizasyon (1)
- Endosomes (1)
- Endothelial (1)
- Endothelial cell (EC) (1)
- Endothelial nitric oxide synthase (1)
- Endothelial progenitor cells (1)
- Endothelial protein C receptor (1)
- Endothelial-to-mesenchymal transition (1)
- Endothelprogenitorzellen (1)
- Endotoxikose (1)
- Endotoxinaktivität (1)
- Endotoxins (1)
- Endourologie (1)
- Endovaskuläre Versorgung (1)
- Endpoint Urea determination (1)
- Endpoints (1)
- Endpunkt-Harnstoffbestimmung (1)
- Energiebedarf (1)
- Energiedefizit (1)
- Energy (1)
- Energy deficit (1)
- Energy metabolism (1)
- Energy-efficiency (1)
- Enfermedades crónicas (1)
- England (1)
- Engraftment (1)
- Enteral nutrition (1)
- Enteric nervous system (1)
- Enterobacterales (1)
- Enterostomy (1)
- Enterostomy closure (1)
- Enterostomy formation (1)
- Entfernung (1)
- Entorhinal cortex lesion (1)
- Entrenamiento práctico (1)
- Entscheidungsfindung (1)
- EnvZ signalling (1)
- Envenomation (1)
- Environmental biotechnology (1)
- Environmental chemistry (1)
- Environmental enrichment (1)
- Environmental impacts (1)
- Environmental sciences (1)
- Enzephalopathie (1)
- Enzymatic Behaviour (1)
- Enzyme Linked Immunosorbent Assay (ELISA) (1)
- Enzyme Preparation (1)
- Enzyme kinetics (1)
- Enzyme mechanisms (1)
- Enzyme regulation (1)
- Eosinophilie (1)
- EpCAM positive tumor (1)
- Ephrin-B2–EphB4 (1)
- Epidemie (1)
- Epidemiological data (1)
- Epidemiologische Surveillance (1)
- Epidermolysis bullosa simplex with muscular dystrophy (1)
- Epidural abscess (1)
- Epidural block (1)
- Epigenetik (1)
- Epilepsiechirurgie (1)
- Epilepsiezentren (1)
- Epilepsy Acute seizure plan Antiseizure medication Instructions for action Self-management (1)
- Epilepsy center (1)
- Epilepsy centers (1)
- Epilepsy surgery (1)
- Epileptic seizure (1)
- Epithel (1)
- Epithelial cells (1)
- Epithelialization (1)
- Epithelioma Cells (1)
- Epsilon (1)
- Epstein–Barr virus (1)
- Equipment (1)
- Eradication (1)
- ErbB-signaling (1)
- Erblichkeit (1)
- Ereigniskorrelierte Felder (1)
- Erfolgsfaktoren (1)
- Ergebnisquantifizierung (1)
- Ergometrie (1)
- Ergometry (1)
- Ergonomic analysis (1)
- Ergonomie am Arbeitsplatz (1)
- Ergonomische Analyse (1)
- Ernährung (1)
- Erprobung (1)
- Erregernachweis (1)
- Erregerspektrum der Tonsillitis (1)
- Erste Hilfe (1)
- Erste-Hilfe-Kurs (1)
- Erwachsener (1)
- Erythema migrans (1)
- Erythematodes (1)
- Erythrocytes (1)
- Erythrophagocytosis (1)
- Erythropoetin (1)
- Erythropoiesis (1)
- Erythropoietin (1)
- Erythrozytenkonzentrat (1)
- Erythrozytentransfusion (1)
- Esophageal adenocarcinoma (1)
- Esophageal adenocarcinoma (EAC) (1)
- Esophagectomy (1)
- Esophagogastric (1)
- Estimated glomerular filtration rate (1)
- Estimation of height and sex determination (1)
- Estradiol (1)
- Estrogen Receptor Modulators (1)
- Ethnicity (1)
- Eugenik (1)
- Eukaryotic sRNA (1)
- European Society for Immunodeficiencies (ESID) (1)
- European babesiosis (1)
- European registry for idiopathic pulmonary fibrosis (eurIPFreg) (1)
- Europäische Gemeinschaften (1)
- Euthanasie (1)
- Euthymic phase (1)
- Evaluation in microsurgery (1)
- Evaluationspraxis (1)
- Event related potentials (1)
- Event-related potential (1)
- Everolimus resistance (1)
- Evidence-based drug discovery (1)
- Evidence-based guidelines (1)
- Evidenz (1)
- Evidenzbasiert (1)
- Evidenzbasierung (1)
- Evolutionary biology (1)
- Ewing-like (1)
- Exacerbations (1)
- Examination questions (1)
- Excitability (1)
- Exemestane (1)
- Exercise Metabolism (1)
- Exercise challenge (1)
- Exercise challenge at an ambient temperature (1)
- Exercise challenge in a cold chamber (1)
- Exercise testing (1)
- Exercise therapy (1)
- Exercise training (1)
- Exercise-induced asthma (1)
- Exercise-induced bronchoconstriction (1)
- Exhaled nitric oxide (1)
- Exoscope (1)
- Exosomal cytokines (1)
- Expansion (1)
- Expectation violation (1)
- Experimental autoimmune encephalomyelitis (1)
- Expert Systems (1)
- Expertensysteme (1)
- Experts (1)
- Explicit (1)
- Explorative Data Analysis (1)
- Explorative Datenanalyse (1)
- Expression (1)
- Extended Glasgow outcome scale (eGOS) (1)
- Extension study (1)
- External beam radiotherapy (1)
- External-/self-assessment (1)
- Extinction (1)
- Extracellular RNA (1)
- Extracellular RNA (eRNA) (1)
- Extracellular signal-regulated kinase 1/2 (1)
- Extracorporeal circulation (1)
- Extracorporeal devices (1)
- Extracorporeal life support (1)
- Extracorporeal purification (1)
- Extrakorporale Dialyse (1)
- Extrakorporaler Kreislauf (1)
- Extraprostatic (1)
- Extreme hypo-fractionation (1)
- Exudates and transudates (1)
- Eye diseases (1)
- EyesiNet (1)
- Ezrin (1)
- F4/80 (1)
- F508del homozygous (1)
- FAAM (1)
- FABP (1)
- FAIR (1)
- FAK (1)
- FAM134 (1)
- FAM134B (1)
- FAP (1)
- FAPI PET (1)
- FAV00A (1)
- FBK-R23 (1)
- FDG-PET/CT (1)
- FDM (1)
- FECD (1)
- FF-ATP synthase dimer (1)
- FFF (1)
- FFP3 respirator (1)
- FFPE (1)
- FHIR Search (1)
- FIB-4 (1)
- FIH1 (1)
- FIV (1)
- FLT3 (1)
- FOLFIRI (1)
- FOXO1 (1)
- FOXO3 (1)
- FOXO3a (1)
- FPR (1)
- FREEDOM (1)
- FSME-Virus (1)
- FSS (1)
- FTMT (1)
- FX06 (1)
- FXR (1)
- Face masks (1)
- Facet joint osteoarthritis (1)
- Facial nerve (1)
- Factor H (1)
- Factor analysis (1)
- FactorXIII Val34Leu polymorphism (1)
- Faculty Development (1)
- Faktor V Leiden Mutation (1)
- Faktor XIII Val34Leu Polymorphismus (1)
- Faktorstruktur (1)
- Falciparum (1)
- Fall (1)
- Fall Leipzig (Kind Knauer) (1)
- Fallbeispiele (1)
- Falls (1)
- Familienanamnese (1)
- Family Physician (1)
- Famines (1)
- Farbmuster (1)
- Fascia (1)
- Fasciculus arcuatus (1)
- Fast Healthcare Interoperability Resources (1)
- Fast-track (1)
- Fat layer (1)
- Fatigue (1)
- Fatiguesyndrom (1)
- Fatty acids (1)
- Fbw7 (1)
- Fc receptor (1)
- Fear conditioning (1)
- Feasibility studies (1)
- Feature tracking (1)
- Feedback loop (1)
- Fehler (1)
- Fehlerberichtssystem (1)
- Fehlerberichtssysteme (1)
- Fehlerverhütung (1)
- Feinstaub (1)
- Feline bartonellosis (1)
- FemNAT-CD (1)
- Female (1)
- Female adolescents (1)
- Female subjects (1)
- Females (1)
- Feminismus (1)
- Femoral neck (1)
- Fendrr (1)
- Ferritinophagy (1)
- Ferroptose (1)
- Ferroptosis (1)
- Fertigkeit (1)
- Fertigkeiten (1)
- Fertility counseling (1)
- Fetal bovine serum (1)
- Fetal heart (1)
- Fettleber (1)
- Fever (1)
- Fevers (1)
- Fibertracking (1)
- Fibrinolytic (1)
- FibroMax (1)
- FibroScan (1)
- Fibroblast (1)
- Fibroblast growth factor (1)
- Fibrotest (1)
- Fibrous dysplasia (1)
- Fibulin-4 (1)
- Fibulin-5 (1)
- Fieberhafter Harnwegsinfekt (1)
- Field of View (1)
- Filariasis (1)
- Filariosis (1)
- Filgrastim (1)
- Filler (1)
- Filovirus cell entry; attachment factors redundancy; SH-SY5Y cell line; host–pathogen interactions (1)
- Finevo (1)
- Finite Element Method (1)
- First experience with patients (1)
- First site of metastatic disease (1)
- First-line combination antiretroviral therapy (1)
- First-line regimen (1)
- Five-Konzept (1)
- Flaubert, Bouvard und Pécuchet (1)
- Flavin mononucleotide (1)
- Flavonoide (1)
- Fleas (1)
- FlexTouch (1)
- Flexibility (1)
- Flexible Endoscopic Evaluation of Swallowing (1)
- Flexur (1)
- Flowzytometrie (1)
- Flugzeitmassenspektrometer (1)
- Flugzeitmassenspektrometrie (1)
- Flugzeitspektrometrie (1)
- Fluid overload (1)
- Fluid therapy (1)
- Fluorescence (1)
- Fluorescence imaging (1)
- Fluorescence-in-situ-hybridization (FISH) (1)
- Fluorescent Probes (1)
- Flüssigkeitsbeatmung (1)
- Foam rolling (1)
- Focal Adhesion Kinase (1)
- Focal onset seizure (1)
- Folgeerkrankungen (1)
- Folic acid (1)
- Follicular lymphoma (1)
- Follow-up (1)
- Follow-ups (1)
- Fondaparinux (1)
- Food and Drug Administration (1)
- Food and beverage precautions (1)
- Food effects (1)
- Foramen ovale (1)
- Forced expiratory volume in 1 s (1)
- Forensic anthropology (1)
- Forensic examination (1)
- Forensic experts (1)
- Forensic osteology (1)
- Forensic pathology (1)
- Forensics (1)
- Forensische Anthropologie (1)
- Forkhead box (1)
- Formation dance (1)
- Forschung (1)
- Forschungspraxisnetz (1)
- Foxp1 (1)
- Fracture (1)
- Fracture models (1)
- Fracture risk (1)
- Fracture type (1)
- Fragebogen (1)
- Frameshift (1)
- Francisella tularensis (1)
- Francisella tularensis subspecies holarctica (1)
- Frankfurt / Zentrum der Rechtsmedizin (1)
- Frankfurt <Main, 1998> (1)
- Frankfurt <Main, Region> (1)
- Frankfurt <Main> / Carolinum, Zentrum der Zahn-, Mund- und Kieferheilkunde (1)
- Frankfurt <Main> / Geographische Gesellschaft (1)
- Frankfurt <Main> / Klinikum (1)
- Frankfurt <Main> / Neurologisches Institut Frankfurt <Main> (1)
- Frankfurt am Main (1)
- Frankfurt am Main, Universität (1)
- Frankfurt am Main, Universitätsmedizin (1)
- Frankfurt microsurgery course (1)
- Frankfurt, Anatomie (1)
- Frankfurt, Universität (1)
- Frankfurt, Universität, Seminar für Geschichte der Medizin (1)
- Frankfurt, Universitätsmedizin 1933-1945 (1)
- Frauen (1)
- Frauenkrankheit (1)
- Freiburg im Breisgau <2009> (1)
- Freie Atmung (1)
- Fresh frozen plasma (1)
- Freud und die Psychoanalyse (1)
- Frontobasal (1)
- Frontotemporal dementia (1)
- Fruit fly (1)
- Frühgeborenes (1)
- Frühsommermeningoenzephalitis (1)
- Fuctional connectivity (1)
- Fukushima (1)
- Functional ankle instability (1)
- Functional capacity (1)
- Functional mitral regurgitation (1)
- Functional outcome (1)
- Functional outcomes (1)
- Functionally-impaired elderly (1)
- Fungemia/diagnosis (1)
- FungiScope® registry (1)
- Fungämie/Diagnostik (1)
- Funktionelle Bildgebung (1)
- Funktionelle NMR-Tomographie (1)
- Funktionsmorphologie (1)
- Further education (1)
- Fusarium (1)
- Fusion Proteins, BCR-ABL (1)
- Füllungswerkstoff (1)
- G-protein (1)
- G-protein-coupled receptors (1)
- G/P (1)
- G207 (1)
- G3BP (1)
- G3BP1 (1)
- G9a/EHMT2/KMT1C (1)
- GABAergic interneurons (1)
- GCH1 (1)
- GD2 (1)
- GDF11 (1)
- GFR (1)
- GHQ-28 (1)
- GIIb/IIIa-receptor (1)
- GLA deficiency (1)
- GLI inhibitors (1)
- GLUT1 (1)
- GM-CSF (1)
- GMP (1)
- GPR4 (1)
- GPVI (1)
- GRADE (1)
- GRAND-SLAM (1)
- GRK2 (1)
- GRX1-roGFP2 (1)
- GSH (1)
- GSK2334470 (1)
- GSK3α (1)
- GSK3β (1)
- GTP cyclohydrolase (1)
- GTPCH1 (1)
- GVHD (1)
- GVL (1)
- Gaba (1)
- Gadopentate dimeglumine (1)
- Gads (1)
- Gallbladder percutaneous drainage (1)
- Gallengangsstenose (1)
- Galleria mellonella (1)
- Galvano (1)
- Games (1)
- Gamma-Band Activity (1)
- Gamma-aminobutyric acid (1)
- Ganglionic (1)
- Ganzheitsmedizin (1)
- Gan–Dou–Fu–Mu decoction (GDFMD) (1)
- Gap junctions (1)
- Gas gangrene (1)
- Gastric adenoma (1)
- Gastric motility (1)
- Gastroenterology (1)
- Gastroesophageal reflux disease (1)
- Gastroesophageal reflux disease symptoms (1)
- Gastrointestinal cancer (1)
- Gastrointestinal neoplasm (1)
- Gastrointestinal tract (1)
- Gaucher disease type III (1)
- Gaucher’s disease (1)
- Gaussian graphical models (1)
- Gebärmutterhalskrebs (1)
- Gedenken (1)
- Gedächtnisbelastung (1)
- Gefallener (1)
- Gefäßinflammation (1)
- Gefäßtonus (1)
- Gegenübertragung (1)
- Gehörlosigkeit (1)
- Gelastic seizures (1)
- Gelastische Anfälle (1)
- Gemcitabine (1)
- Gemifloxacin (1)
- Genamplifikation (1)
- Gender analysis (1)
- Gender equality (1)
- Gender gap (1)
- Gene (1)
- Gene Polymorphism (1)
- Gene Transfer (1)
- Gene engineering (1)
- Gene expression prediction (1)
- Gene microarray analysis (1)
- Gene polymorphism (1)
- Gene prediction (1)
- Gene sequencing (1)
- Gene set analysis (1)
- Gene-Amplification (1)
- Gene-protein assay (1)
- Gene/Regulation (1)
- GeneMANIA (1)
- General Practitioner (1)
- General clinical cardiology (1)
- General dental practice (1)
- General practice/family medicine (1)
- General practitioner (1)
- Generalized procrustes analysis (1)
- Generation Y (1)
- Generation of reports on special findings in laboratory medicine (1)
- Generation time (1)
- Generic drugs (1)
- Genetic causes of cancer (1)
- Genetic heart disease (1)
- Genetic loci (1)
- Genetic networks (1)
- Genetic syndromes (1)
- Genetic techniques (1)
- Genfamilie (1)
- Genklonierung (1)
- Genome annotation (1)
- Genome editing (1)
- Genome-wide association study (1)
- Genomic instability (1)
- Genomic medicine (1)
- Genregulation (1)
- Gentherapie (1)
- Geographical disparities (1)
- Geriatrie (1)
- Gerinnungsfaktor IX (1)
- Gerinnungsfaktor XIII (1)
- German (1)
- German PID-NET registry (1)
- German Society of Surgery (1)
- Gerontologic legal medicine (1)
- Gerontologische Rechtsmedizin (1)
- Gesamteiweißbestimmung im Harn (1)
- Gesang (1)
- Geschichte 1847-1970 (1)
- Geschichte 1914-2014 (1)
- Geschichte 1919 (1)
- Geschichte 1930-1940 (1)
- Geschichte 1933-1945 (1)
- Geschichte 1938 (1)
- Geschichte 1939-1940 (1)
- Geschichte 1960-1986 (1)
- Geschichte 1972-2002 (1)
- Geschichte 1973-1998 (1)
- Geschichte der Medizin Frankfurt (1)
- Geschlechtsdysphorie bei Kindern und Jugendlichen (1)
- Geschlechtsidentitätsstörungen im Kindes- und Jugendalter (1)
- Gesetzentwurf (1)
- Gesprächsführung (1)
- Gestagen-Monopräparate (1)
- Gestational age (1)
- Gestational diabetes (1)
- Gestationshyperthyreose (1)
- Gesundheitsamt (1)
- Gesundheitskommunikation (1)
- Gesundheitspersonal (1)
- Gesundheitspolitische Zuständigkeit (1)
- Gesundheitsversorgungseinrichtungen (1)
- Gewalt (1)
- Giant lymph node hyperplasia (1)
- Gift (1)
- Giftgas (Lost) (1)
- Gimbaled tracking (1)
- Girdlestone (1)
- Glabella (1)
- Gleason Grade Group (1)
- Gleason Grade group (1)
- Gleason Score (1)
- Gleason grade group (1)
- Gleason upgrading (1)
- Glia Maturation Factor (1)
- Glioblastoma survival (1)
- Glivec® (1)
- Global networking (1)
- Global protein synthesis rates (1)
- Global warming (1)
- Glomerular Filtration Rate (1)
- Glomerular diseases (1)
- Glomerulonephritis (1)
- Glomerulosclerosis (1)
- Glucocorticoids (1)
- Glucose Transporter Type 1 (1)
- Glukose (1)
- Glyceraldehyde-3 Phosphate Dehydrogenase (1)
- Glyceraldehyde-3-phosphate Dehydrogenase (1)
- Glycogen synthase kinase 3 beta (1)
- Glycosphingolipids (1)
- Glyoxalase I (1)
- Goal-oriented care (1)
- Gold (1)
- Gonarthrose (1)
- Goserelin (1)
- Gradient boosting (1)
- Grading (1)
- Grado en medicina (1)
- Graft (1)
- Graft function (1)
- Graft quality (1)
- Graft survival (1)
- Gram negative bacteria (1)
- Gram-negative bacteria (1)
- Gram-positive Bakterien ; Linezolid ; Arzneimittelresistenz (1)
- Gram-positive Bakterien ; Moxifloxacin ; Arzneimittelresistenz (1)
- Gram-positive infection (1)
- Granule cell (1)
- Granulocytes (1)
- Graph Machine Learning (1)
- Graph Neural Networks (1)
- Graph theory (1)
- Graphical LASSO (1)
- Grass pollen (1)
- Graves' (1)
- Graves’ disease (1)
- Gravimetric method (1)
- Graz <2013> (1)
- Greater tuberosity fractures (1)
- Green Tobacco Sickness (GTS) (1)
- Greenhouse effect (1)
- Grenzwert (1)
- Groin pain (1)
- Gross tumor volume optimization (1)
- Grossesse (1)
- Growth cone (1)
- Growth factor (1)
- Growth factor signalling (1)
- Großhirnrinde (1)
- Grün fluoreszierendes Protein (1)
- Guidance (1)
- Guide profession (1)
- Guided bone regeneration (GBR) (1)
- Guided surgery (1)
- Guided tissue regeneration (1)
- Guided tissue regeneration (GTR) (1)
- Guideline adherence (1)
- Guideline-based treatment (1)
- Gut (1)
- Gut bacteria (1)
- Gut-liver-axis (1)
- GvHD (1)
- GvL (1)
- Gynäkologie (1)
- Gyrasehemmer (1)
- Görden, Anstalt (1)
- Güntz, Eduard (1)
- Gütt, Arthur (1)
- Gαq/11 (1)
- H-Index (1)
- H3 receptor (1)
- H5N1 (1)
- HACA (1)
- HADS (1)
- HAEGARDA (1)
- HAI‐1 (1)
- HARS2 (1)
- HBV filaments (1)
- HBV genotypes (1)
- HBV reactivation (1)
- HBV surface protein (1)
- HCC marker (1)
- HCC recurrence (1)
- HCV treatment (1)
- HCV-Core-Antigen (1)
- HDAC and BET inhibitor (1)
- HDAC inhibition (1)
- HDAC-inhibition (1)
- HDAC4 (1)
- HDR-Brachytherapie (1)
- HDR-brachytherapy (1)
- HEOR (1)
- HER2 c-erbB2 (1)
- HER2-positive (1)
- HER2/neu (ERBB2) (1)
- HEUS (1)
- HEV (1)
- HFrEF (1)
- HGF (1)
- HH (1)
- HHUSD (1)
- HHV-8 (1)
- HIBCPP cells (1)
- HIF-1 (1)
- HIF-1α (1)
- HIF-2 (1)
- HIF-2α (1)
- HIF-2α, erythropoietin (1)
- HIF1α (1)
- HIFU (1)
- HILI (1)
- HIPPO signalling (1)
- HIT (1)
- HIV serodiagnosis (1)
- HIV therapy (1)
- HIV-1 Genotypisierung (1)
- HIV-1 escape restriction (1)
- HIV-1 genotyping (1)
- HIV-Antigen-Test (1)
- HIV-Infektionen (1)
- HIV-Infizierter (1)
- HIV-RNA (1)
- HIV-infected patient (1)
- HIV-infection (1)
- HLA DQ haplotypes (1)
- HLA class I loss (1)
- HLA class II (1)
- HLA peptidome (1)
- HLHS (1)
- HMA (1)
- HMGB1 (1)
- HNO (1)
- HNPCC (1)
- HODE (1)
- HOLEP (1)
- HOSO (1)
- HOTAIR (1)
- HPO (1)
- HPV infection (1)
- HPV-positive OPSCC (1)
- HRCT (1)
- HRV (1)
- HRas (1)
- HSC (1)
- HSP (hereditary spastic paraplegia) (1)
- HSPC (1)
- HSV type specific antibodies (1)
- HSV-2 (1)
- HSV-typenspezifische Antikörper (1)
- HUVEC (1)
- HVPG (1)
- Haaranalyse (1)
- Hadamar (1)
- Haematocrit (1)
- Haematologic diseases (1)
- Haematoma expansion (1)
- Haematopoietic stem cells (1)
- Haemodialysis (1)
- Haemodynamic monitoring (1)
- Haemophilia (1)
- Haemophilie A (1)
- Haemostatics (1)
- Half-of-the-Sites Reactivity (1)
- Halogenobenzimidazoles (1)
- Hals-Nasen-Ohren-Heilkunde (1)
- Hamburg <2014> (1)
- Hand-foot syndrome (1)
- Handlungsanweisungen (1)
- Haploidentical stem cell transplantation (1)
- Haplotypes (1)
- Hard-tissue trauma (1)
- Hard-to-reach population (1)
- Hardware erosion (1)
- Harnsteinanalyse (1)
- Harnsteinkomponenten (1)
- Hashimoto (1)
- Hashimoto Thyreoiditis (1)
- Hashimoto’s thyroiditis (1)
- Hausarzt (1)
- Hautlokalisation (1)
- Hawaii Department of Health (1)
- HbA1c (1)
- HeLa cells (1)
- Head and neck Cancer (1)
- Head bandage (1)
- Head injury (1)
- Head neck cancer (1)
- Health Communication (1)
- Health Policy (1)
- Health Systems (1)
- Health care access (1)
- Health care resource utilization (1)
- Health care sector (1)
- Health care structures (1)
- Health education and awareness (1)
- Health facilities (1)
- Health information (1)
- Health literacy (1)
- Health personnel (1)
- Health risk analysis (1)
- Health sciences (1)
- Health services research [MeSH] (1)
- Health surveys (1)
- Health technology assessment (1)
- Health-related quality of life (1)
- Health-seeking behaviour (1)
- Healthcare (1)
- Healthcare resource utilisation (1)
- Healthcare structure (1)
- Healthy Living Index (HLI) (1)
- Healthy men (1)
- Healthy stem cell donors (1)
- Health‐related quality of life (1)
- Heart defects (1)
- Heart rate (1)
- Heart regeneration (1)
- Heartrate (1)
- Heat Shock Protein (HSP) (1)
- Heat dissipation (1)
- Heat pain (1)
- Heat shock protein 27 (1)
- Hebbian plasticity (1)
- Heben (1)
- Hedgehog (1)
- Hedgehog pathway (1)
- Heimtraining (1)
- Heinz-Jürgen Voss (1)
- Helpline (1)
- Hemagglutination inhibition assay (1)
- Hematocrit value (1)
- Hematologic adverse events (1)
- Hematoma (1)
- Hematopoietic stem and progenitor cells (HSPCs) (1)
- Hematopoietic stem cell (1)
- Hematopoietic stem cell transplant (1)
- Hematopoietic stem cell transplantation (1)
- Hematopoietic stem cells (1)
- Hematotoxicity (1)
- Hematoxylin staining (1)
- Heme-Oxygenase 1 (1)
- Hemikraniektomie (1)
- Hemispheric specialization (1)
- Hemobilia (1)
- Hemodialyse (1)
- Hemodilution (1)
- Hemodynamic management (1)
- Hemoglobin (1)
- Hemophilia A (1)
- Hemorrhagic shock (1)
- Hemosiderin (1)
- Hemostasis (1)
- Hemostatics (1)
- HepG2 Zellen (1)
- HepaRG cells (1)
- Heparan Sulfate (1)
- Heparin (1)
- Heparinsensitivität (1)
- Hepatectomy (1)
- Hepatic encephalopathy (1)
- Hepatic stellate cell (1)
- Hepatitis B Antibodies/serum (1)
- Hepatitis B Core-Antigene/Immunologie (1)
- Hepatitis B infection (1)
- Hepatitis B vaccination (1)
- Hepatitis B virus (1)
- Hepatitis B-Antikörper/Serum (1)
- Hepatitis B-Core-Antigens-immunology (1)
- Hepatitis C antibodies (1)
- Hepatitis C antigens (1)
- Hepatitis C, Chronic (1)
- Hepatitis C-Virus (HCV) (1)
- Hepatitis C; DNA (1)
- Hepatitis G virus (1)
- Hepatitis G-Virus (1)
- Hepatitis c (1)
- Hepatitis, Chronic Active/diagnosis (1)
- Hepatoblastom (1)
- Hepatocellular carcinoma (HCC) (1)
- Heptazelluläres Karzinom (1)
- Her2-neu (1)
- Herafill (1)
- Herbal medicine (1)
- Herbalife (1)
- Herbalife products (1)
- Herbs (1)
- Herbs induced liver injury (1)
- Herd immunity (1)
- Hereditary breast and ovarian cancer (1)
- Hereditary breast cancer (1)
- Hereditary ovarian cancer (1)
- Hereditäre Thrombophilie (1)
- Heregulin (1)
- Hernia recurrence (1)
- Hernia surgery (1)
- Herniated disk (1)
- Herpe-Viren (1)
- Herpes Simplex Virus/isolation and purification . (1)
- Herpes genitalis (1)
- Herpes simplex (1)
- Herpes simplex Virus Typ 1 (1)
- Herpes simplex Virus Typ 2 (1)
- Herpes simplex Virus/Isolierung und Anreicherung (1)
- Herpes simplex virus type 1 (1)
- Herpes simplex virus type 2 (1)
- Herpes virus (1)
- Herpesvirus 1, Humanes (1)
- Herpesvirus 2, Human (1)
- Herpesvirus 2, Humanes (1)
- Herpesvirus1, Human (1)
- Herz-Kreislauffunktion (1)
- Herzchirurgie (1)
- Herzindex (1)
- Herzinfarkt (1)
- Herzkatheteruntersuchung (1)
- Heterologous prime-boost (1)
- Heterotopic pregnancy (1)
- Heuristik (1)
- Hexavalent vaccine (1)
- HhAntag (1)
- HiC (1)
- HiChIP (1)
- Hidradenitis suppurativa (1)
- Hierarchical drift-diffusion modeling (1)
- Hif-1 alpha (1)
- Hif1α (1)
- Hig1 (1)
- High altitude (1)
- High radon areas (1)
- High-dose chemotherapy (1)
- High-income countries (1)
- High-intensity interval endurance training (1)
- High-risk cardiac surgery (1)
- High-risk patient (1)
- High-risk prostate cancer (1)
- High-throughput screening (1)
- Highly infectious diseases (1)
- Highwire (1)
- Himalayas (1)
- Hindu Kush Himalayas (1)
- Hip (1)
- Hip hemiarthroplasty (1)
- Hip revision (1)
- Hippo signaling (1)
- Hippocampal excitability (1)
- Hippocampal volume (1)
- Hippokrates, Asteroid (1)
- Hirnkrankheit (1)
- Hirnmetastasen (1)
- Hirntumor (1)
- Hirnverletzung (1)
- Hirschsprung disease (1)
- Hirt, August (1)
- Hispanic people (1)
- Hispanic–Latino race/ethnicity (1)
- Histological analysis (1)
- Histone post-translational modifications (1)
- Histonmethylierung (1)
- Histoplasma qPCR (1)
- Hitachi 705 (1)
- HlV-Infections (1)
- Hmox1 (1)
- Hochansteckende Krankheiten (1)
- Hochdurchsatz (1)
- Hochfrequenz-Katheterablation (1)
- Hochschuldidaktik (1)
- Hodgkin-Lymphom (1)
- Hodgkin’s lymphoma (1)
- Holmium laser enucleation (1)
- Home Care Services [MeSH] (1)
- Homeostatic plasticity (1)
- Hometraining (1)
- Homicide-suicide (1)
- Homizid-Suizid (1)
- Homocysteine (1)
- Homonationalismus (1)
- Honolulu Queen’s Medical Center (1)
- Hormonal (1)
- Hormone (1)
- Hormone de régression müllérienne (1)
- Hormone receptor positive breast cancer (1)
- Hormonelle Kontrazeptiva (1)
- Hormones thyroïdiennes (1)
- Horner's syndrome (1)
- Hornhauttransplantation (1)
- Horses (1)
- Hospital case volume (1)
- Hospitalization (1)
- Hospitalizations (1)
- Host-directed therapies (1)
- Host-targeting agents (HTAs) (1)
- Hounsfield units (1)
- Hounsfieldeinheit (1)
- House dust mite allergy (1)
- Household contacts (1)
- Hrvaška (1)
- Hsp70 (1)
- Hsp90 inhibitor (1)
- Huh7 (1)
- Human (1)
- Human Immunodeficiency Virus (1)
- Human chorionic villi mesenchymal stromal cells (1)
- Human experimental pain models (1)
- Human immunodeficiency virus (HIV) (1)
- Human olfaction (1)
- Human pancreas (1)
- Human physiology (1)
- Human primary proximal tubular cells (1)
- Human prostate (1)
- Human retroelements (1)
- Human visual cortex (1)
- Humangenetik (1)
- Humans (1)
- Humeral fractures (1)
- Humerus (1)
- Humerus fracture (1)
- Humerusfraktur (1)
- Hungary (1)
- Hyaluronan (1)
- Hybrid Formation (1)
- Hydrocephalus (1)
- Hydrocortison (1)
- Hydrocortisone (1)
- Hydrofluoric acid (1)
- Hydromineral (1)
- Hydroxyapatite (1)
- Hydroxychloroquine (1)
- Hydroxycut (1)
- Hydroxyethyl starch (1)
- Hydroxyurea (1)
- Hygienestandards (1)
- Hymenoptera venom allergy (1)
- Hymenoptera venom immunotherapy (1)
- Hyperactivity (1)
- Hyperammonemic encephalopathy (1)
- Hyperhidrosis axillaris (1)
- Hyperlipidemia (1)
- Hyperlipidämie (1)
- Hyperscanning (1)
- Hypertensive disorders in pregnancy (1)
- Hyperthyroïdie gestationnelle (1)
- Hypofractionated radiotherapy (1)
- Hypokalzämie (1)
- Hyponatremia (1)
- Hypoparathyreoidismus (1)
- Hyposensibilisierung (1)
- Hypothyreose (1)
- Hypothyroïdie (1)
- Hypoxia inducible factor (1)
- Hypoxia inducible factor 1 alphal (1)
- Hypoxia-inducible factor-1α (HIF-1α) (1)
- Hypoxic responses (1)
- Hypoxie (1)
- Hysterektomie-Prävalenz (1)
- Häm-Oxygenase 1 (1)
- Hämatotoxizität (1)
- Hämodynamik Shunt (1)
- Hämophile Arthropathie (1)
- Hämophilie (1)
- Händehygiene (1)
- Höchstrichterliche Rechtsprechung (1)
- Höhren (1)
- Hörscreening (1)
- I-FABP (1)
- I-PRF (1)
- IAP (1)
- IAP Proteins (1)
- IAP-IAP (1)
- ICAM-1 (1)
- ICG (1)
- ICH M13A draft guideline (1)
- ICSD (1)
- ICSI (1)
- IDH1 inhibitor (1)
- IDO1 (1)
- IDT (1)
- IFA (1)
- IFN (1)
- IFN-β (1)
- IFN-γ expression (1)
- IGF (1)
- IGF-1 (1)
- IGF1 (1)
- IGRA (1)
- IKKε (1)
- IKZF1 (1)
- IL -17 (1)
- IL -23 (1)
- IL 23p19 knockout mouse (1)
- IL-11 (1)
- IL-13 (1)
- IL-15 (1)
- IL-17 (1)
- IL-17A (1)
- IL-18 binding protein (1)
- IL-18BP (1)
- IL-1b (1)
- IL-21 (1)
- IL-22 (1)
- IL-23 (1)
- IL-27 cytokine (1)
- IL-38 (1)
- IL10R (1)
- ILUVIEN (1)
- IMiD® (1)
- INR (1)
- IPEX (1)
- IPP (1)
- IPS e.max system (1)
- IPSS (1)
- IR (1)
- IRES translation (1)
- IRF-3 (1)
- IRIS (1)
- ISO (1)
- ISRS (1)
- ISS (1)
- ITGA7 (1)
- IUIS classification 2017 (1)
- IV iron (1)
- IVA interference tandem mass spectrometry (1)
- IVD (1)
- IVD degeneration (IVDD) (1)
- IVD directive (1)
- IVD-Richtlinie (1)
- IVDU (1)
- IVF (1)
- IVUS (1)
- Iatrogen (1)
- Iatrogenic (1)
- Iceland (1)
- Idarucizumab (1)
- Idelalisib (1)
- Identifier (1)
- Identifikation (1)
- Identifizierung von Katastrophenopfern (1)
- Identity (1)
- Idiopathic pulmonary fibrosis (IPF) (1)
- Idiopathische Dystonie (1)
- Ig (sub)class-specific antibody determination (1)
- Ig- (sub)klassen-spezifische Antikörperbestimmung (1)
- IgA deficiency (1)
- IgE (1)
- IgG (1)
- IgG substitution therapy (1)
- IgG4-related disease (1)
- IgGAM (1)
- IgM/Immunologie (1)
- IgM/immunology (1)
- Ileostomy (1)
- Illumina (1)
- Image processing (computer-assisted) (1)
- Imagery (1)
- Imaging (1)
- Imaging genetics (1)
- Imaging in LGG (1)
- Imaging, three-dimensional (1)
- Imatinib (1)
- Imdevimab (1)
- Immediate loading (1)
- Immediate placement (1)
- Immobilization (1)
- Immortalisierung (1)
- Immune Complexes (1)
- Immune Response (1)
- Immune checkpoint inhibitors (1)
- Immune complex vasculitis (1)
- Immune paralysis (1)
- Immune receptor signaling (1)
- Immune response (1)
- Immune status (1)
- Immunfixations-Elektrophorese (1)
- Immunglobulinklassen und -subklassen (1)
- Immunhyperthyreose (1)
- Immunität (Medizin) (1)
- Immunitätsbeurteilung (1)
- Immunkomplexe (1)
- Immunnephelometrie (1)
- Immunoassay (1)
- Immunoassays (1)
- Immunocompromised (1)
- Immunodeficiency (1)
- Immunofluoreszenz (1)
- Immunogenetics (1)
- Immunoglobulin Therapy (1)
- Immunoglobulin classes and -subclasses (1)
- Immunoglobulins (1)
- Immunohistochemistry techniques (1)
- Immunologic methods (1)
- Immunological techniques (1)
- Immunologie Methods (1)
- Immunology and Microbiology Section (1)
- Immunomagnetische Antikörper (1)
- Immunomodulation (1)
- Immunomodulatory agents (1)
- Immunomonitoring (1)
- Immunonephelometry (1)
- Immunophenotyping (1)
- Immunosenescence (1)
- Immunoseneszenz (1)
- Immunostaining (1)
- Immunosuppressive Agents (1)
- Immunosuppressive agents (1)
- Immunosuppressive therapy (1)
- Immunoturbidimetry (1)
- Immuno‑histochemistry (1)
- Immunreaktion (1)
- Impedanzaggregometrie (1)
- Impfkurs (1)
- Impfquoten (1)
- Implant osseointegration (1)
- Implant-supported bars (1)
- Implantable cardioverter-defibrillator (1)
- Implantat (1)
- Implementación (1)
- Implicit (1)
- Implicit Processing (1)
- Implicit Association Test (1)
- Implicit motives (1)
- Impoverishment (1)
- Impräzision (1)
- Impulse control (1)
- Impulse generator (1)
- Imrt (1)
- In vivo electrophysiology (1)
- In-ASK Studie (1)
- In-Hospital Emergencies (1)
- In-TIPS thrombosis (1)
- In-hospital cardiac arrest (1)
- In-line filtration (1)
- In-vitro-Kultur (1)
- In-vivo (1)
- Inactivation (1)
- IncL (1)
- IncX (1)
- Incident reporting system (1)
- Incidental prostate cancer (1)
- Incomplete colonoscopy (1)
- Incontinence (1)
- Independent component analysis (1)
- Independent laboratories (1)
- Indeterminate biliary stricture (1)
- Index (1)
- Indication (1)
- Indication for fertility preservation (1)
- Indirect treatment comparison (ITC) (1)
- Individual differences (1)
- Individualisierung des Studiums (1)
- Individualized intervention (1)
- Individualized therapy (1)
- Individuelle Studienbegleitung (1)
- Indocyanine green (1)
- Indoor air pollution (1)
- Induced membrane technique (1)
- Induced pluripotent stem cells (1)
- Induced sputum (1)
- Inducible nitric oxide synthase (iNOS) (1)
- Induction therapy (1)
- Induratio penis plastica (1)
- Inequality (1)
- Inertial motion capture (1)
- Infant (1)
- Infant leukemia (1)
- Infants (1)
- Infarction (1)
- Infectious disease (1)
- Infectious disease epidemiology (1)
- Infektionen (1)
- Infektionsabwehr (1)
- Infektionsprophylaxe (1)
- Infertilität (1)
- Inflammasome (1)
- Inflammatory fibroid polyp (1)
- Inflammatory pattern (1)
- Infliximab (1)
- Inflow obstruction (1)
- Influenza vaccination (1)
- Information transfer (1)
- Informiertheit (1)
- Infrared Raman (1)
- Infrarotspektroskopie (1)
- Infusion management (1)
- Inguinal hernia (1)
- Inguinal pain (1)
- Inherited arrhythmic syndrome (1)
- Injury Severity Score (ISS) (1)
- Inner ear therapy (1)
- Inpatient hospital cases (1)
- Inpatients (1)
- Inside-out Signaling (1)
- Instructions for action (1)
- Insula (1)
- Insulin resistance (1)
- Insulin secretion (1)
- Insulin therapy (1)
- Insulintherapie (1)
- Integrated Pulmonary Index (1)
- Integrated multimodal training (1)
- Integrative Network Analysis (1)
- Integrins (1)
- Intelligence (1)
- Intelligence tests (1)
- Intensive care outcome (1)
- Intensive care unit (1)
- Intensivpatient (1)
- Intention attribution (1)
- Inter-study reproducibility (1)
- Interaction (1)
- Interaktion (1)
- Interaktionsdatenbanken (1)
- Interdisziplinarität (1)
- Interferon alpha (1)
- Interferon-free (1)
- Interferon-free HCV treatment (1)
- Interferon-frei (1)
- Interferon-α (1)
- Interferon-λ, (1)
- Interferonfrei (1)
- Interferons (1)
- Interleukin-10 (1)
- Interleukin-17A (1)
- Interleukin-18 (1)
- Interleukin-18 binding protein (1)
- Interleukin-22 binding protein (1)
- Interleukin-36 (1)
- Interleukine (1)
- Intermediate filaments (1)
- Intermediate-risk (1)
- International body passport (1)
- International normalized ratio (1)
- Internationale Wettbewerbsfähigkeit (1)
- Internationaler Vergleich (1)
- Internationaler Wettbewerb (1)
- Internet citation (1)
- Internet technology (1)
- Internet-based therapy (1)
- Internettechnologie (1)
- Interoperability (1)
- Interposition (1)
- Interpretation Bias (1)
- Interrater Reliability (1)
- Interraterreliabilität (1)
- Intersectoral care (1)
- Interspecific competition (1)
- Interstitial lung diseases (ILD) (1)
- Interstitial pneumonia (1)
- Intervention (1)
- Intervention development (1)
- Interventional Trials (1)
- Interventional cardiology (1)
- Interventional oncological treatment (1)
- Intervertebral disc degeneration (1)
- Intervertebral disc displacement (1)
- Interviews (1)
- Intestinal failure-associated liver disease (1)
- Intestinal fistula (1)
- Intestinal metaplasia (1)
- Intestinal neoplasms (1)
- Intestinale bakterielle Fehlbesiedelung (1)
- Intimal-medial thickness (1)
- Intolerance (1)
- Intoxication (1)
- Intoxikation (1)
- Intra-abdominal infection (1)
- Intracellular pathogens (1)
- Intracerebral haemorrhage (1)
- Intracranial embolism (1)
- Intracranial haemorrhage (1)
- Intracranial hemorrhage (1)
- Intragastric balloon (1)
- Intraoperative blood salvage (1)
- Intraoperative procedure (1)
- Intraoperative test (1)
- Intraoral scanners (1)
- Intraosseous access (1)
- Intratumoral (1)
- Intratympanic drug delivery (1)
- Intravenous Drug User (1)
- Intravenous antibiotic therapy (1)
- Intravenous antiepileptics (1)
- Intravenous injections (1)
- Intravenous iron (1)
- Intravenöse Antiepileptika (1)
- Intrazellulärer Transport (1)
- Intrinsic Disorder (1)
- Intrinsic resistance (1)
- Intubation (1)
- Intubation anesthesia (1)
- Intubationsnarkose (1)
- Invasive candidiasis (1)
- Invasive fungal infection (1)
- Invasive fungal infections (1)
- Inzidenzkorrektur (1)
- Iod (1)
- Iodmangel (1)
- Ionenkanal (1)
- Ionization State (1)
- Ipilimumab (1)
- Ireb2 (1)
- Ireland (1)
- Iridium-192 (1)
- Iron Overload (1)
- Iron chelation (1)
- Iron estimation (1)
- Irregular vaccination (1)
- Ischemia-reperfusion injury (1)
- Ischemia–reperfusion injury (1)
- Ischemic stroke (1)
- Isocitrate dehydrogenase (1)
- Isoflurane (1)
- Isoforms (1)
- Isolierung (1)
- Isolierung <Medizin> (1)
- Isoproterenol (1)
- Isothermal amplification (1)
- Isotope labeling (1)
- Issue 96 (1)
- Italy (1)
- Itpr1 (1)
- Ivor Lewis esophagectomy (1)
- JAK inhibition (1)
- JAK2V617F (1)
- JNK (1)
- JNK3 (1)
- Jak2(V617F) (1)
- Java <Programmiersprache> (1)
- Jaw surgery (1)
- JawsII (1)
- Job satisfaction (1)
- Jodausscheidung im Urin (1)
- Joint actions (1)
- Joint destruction (1)
- Joubert syndrome (1)
- Jugend (1)
- Jumping (1)
- Jurkat (1)
- Juvenile myoclonic epilepsy (1)
- Jüdische Dozenten Frankfurt (1)
- K-homology RNA-binding domain (1)
- K3EDTA plasma sampling (1)
- KAP (1)
- KCCQ (1)
- KCGS (1)
- KCNJ2 mutation (1)
- KCNQ1 (1)
- KCNQ4 (1)
- KDIGO (1)
- KIF (1)
- KIF11 (1)
- KIR (1)
- KLHL11 (1)
- KLK5 (1)
- KOOS IV (1)
- KPS (1)
- KRAS (1)
- KSHV epidemiology (1)
- KSHV, Epidemiologie (1)
- Kachexie (1)
- Kaiserschnitt (1)
- Kaisidis plate (1)
- Kallestad QM 300 (1)
- Kallestad QM 30 (1)
- Kallikrein inhibitor (1)
- Kandidatengen (1)
- Kanzlei des Führers (1)
- Kapazitätsdefizit (1)
- Kapitalismus (1)
- Kaplan-Meier-Schätzung (1)
- Kapnographie (1)
- Kappa (1)
- Kardiomyopathie (1)
- Kardiovaskuläres Risiko (1)
- Karies (1)
- Karyotypes (1)
- Karzinom (1)
- Karzinomzellen (1)
- Katamnese Transidentität im Kindes- und Jugendalter (1)
- Kataraktchirugie (1)
- Katheterablation (1)
- Kava (1)
- Kava hepatotoxicity (1)
- Kavitätenpräparation (1)
- Keap1-Nrf2 (1)
- Kegelschnecke (1)
- Kephalometrie mit Magnetinduktion (1)
- Kephalometrie ohne Röntgenstrahlen (1)
- Keratinocytes (1)
- Keratoplastik (1)
- Ketogenic Diet (1)
- Ketolide (1)
- Ki-67/MIB1 (1)
- Ki67 transgenic c‐myc/TGFα mice (1)
- Kidney Transplantation (1)
- Kidney disease (1)
- Kidney diseases (1)
- Kidney neoplasm (1)
- Kidney transplant recipients (1)
- Kidneys (1)
- Kiefer (1)
- Kieferhöhlenentzündung (1)
- Kim-1 (1)
- Kinder und Jugendliche (1)
- Kinderchirurgie (1)
- Kinderheilkunde (1)
- Kinderkrankheit (1)
- Kindertagesstätten (1)
- Kindes- und Jugendalter (1)
- Kindestötung (1)
- Kindheit (1)
- Kindspech (1)
- Kinematic posture analysis (1)
- Kinematics (1)
- Kinetochore (1)
- Kleinkind (1)
- Klinikum <Frankfurt, Main> / Bericht (1)
- Klinische Fertigkeiten (1)
- Knee joint (1)
- Knee joint sound (1)
- Knee osteoarthritis (1)
- Knee surgery (1)
- Kniegelenkarthrose (1)
- Kniegelenkinfekt (1)
- Knieinfekt (1)
- Knochenabbau (1)
- Knochendefektheilung (1)
- Knochenevaluation (1)
- Knochenmetastasen (1)
- Knockout (1)
- Koch, Richard (1)
- Kodieralgorithmus (1)
- Kognitiv (1)
- Kognitive Beeinträchtigungen (1)
- Kombinationstherapie (1)
- Kombinationstherapien (1)
- Kommerzielle Immunglobuline (1)
- Komorbiditäten (1)
- Komplementbindungsreaktion (KBR) (1)
- Komplementsystem (1)
- Komplikation allogene Stammzelltransplantation (1)
- Komplikationsrate (1)
- Komposit (1)
- Komprimierte Abtastung (1)
- Konformitätsbewertung (1)
- Kongress <Wandlitz, 1997> (1)
- Konsens (1)
- Konsensus Methode (1)
- Kontaktallergie (1)
- Kontrastmittel (1)
- Kontrazeption (1)
- Kontrollierte klinische Studie (1)
- Konusprothese (1)
- Konversion (1)
- Konzeption (1)
- Konzeptpapier (1)
- Kopfhaar (1)
- Kopfstimme (1)
- Koronare Herzkrankheit (1)
- Korporatismus (1)
- Korporativer Staat (1)
- Korrektheit (1)
- Kortikale Dicke (1)
- Kortikotrope Achse (1)
- Krait (1)
- Kraniomandibuläre Dysfunktion (1)
- Krankenhausfallaufkommen (1)
- Krankenhausinformationssystem (1)
- Krankheit (1)
- Krankheitskosten (1)
- Kreatinin (1)
- Krebs (Medizin) (1)
- Krebs <Medizin> (1)
- Krebsfamiliensyndrom (1)
- Krebsforschung (1)
- Krebststammzelle (1)
- Kupfer (1)
- Kupffer cells (1)
- Kurzzeitgedächtnis (1)
- Kutner, Luis (1)
- Kynurenine (1)
- Körper (1)
- Körpergrößenschätzung, Geschlechtsdiskrimination (1)
- Körperliche Aktivität (1)
- Körperliche Belastung (1)
- Körpermaße (1)
- Körpermodifikation (1)
- Körpermodifizierung (1)
- L1 cell-adhesion molecule (L1-CAM) (1)
- L1-norm SVM (1)
- LABAs (1)
- LAMP3 (1)
- LAMTOR1 (1)
- LAMTOR2 (1)
- LARS2 (1)
- LASS (1)
- LAT (1)
- LC-MS (1)
- LC-MS-Based Clinical Research (1)
- LC-MS-based lipid mediator analysis (1)
- LC-NE system (1)
- LC3 I/II (1)
- LC3B (1)
- LCD-Array (1)
- LCH (1)
- LC–MS/MS (1)
- LD 2 Ringe (1)
- LD 2 rings (1)
- LDHB (1)
- LDL (1)
- LDL-cholesterol (1)
- LEOSS (1)
- LFA-1 (1)
- LFP (1)
- LHRH receptor (1)
- LIR interaction, (1)
- LIVIN (1)
- LM11A 31 (1)
- LN229 (1)
- LNS (1)
- LOS (1)
- LPP (1)
- LQTS (1)
- LRBA (1)
- LSD1 (1)
- LSEC (1)
- LTB4 (1)
- LTBI (1)
- LU-102 (1)
- LUBAC (1)
- LUT (1)
- Label-free (1)
- Laboratory techniques and procedures (1)
- Labordiagnose (1)
- Labormedizin (1)
- Labormedizinische Spezialbefundung (1)
- Labororganisation (1)
- Laborpersonal (1)
- Lack of immunity (1)
- Lactation (1)
- Lactic acidosis (1)
- Lactobacillus (1)
- Lacunar (1)
- Lafora disease (1)
- Lagerungsbedingungen (1)
- Lakunär (1)
- Laminin (1)
- Lamivudine (1)
- LanCL2 (1)
- Landmark (1)
- Langstreckige Knochendefekte (1)
- Language delay (1)
- Langzeiteffekt (1)
- Langzeitergebnis (1)
- Langzeitpflege (1)
- Laparoscopic fundoplication (1)
- Laparostomy (1)
- Laparotomy. Joel-Cohen (1)
- Laparscopic Bariatric Surgery (1)
- Large vessel occlusion (1)
- Laryngeal Tube (1)
- Laser interstitial thermal therapy (1)
- Laser navigation system (1)
- Laser-Doppler-Signal (1)
- Lasers (1)
- Lasertherapie (1)
- Late Gadolinium Enhancement (LGE) (1)
- Late gadolinium enhancement (1)
- Late presentation (1)
- Latent transforming growth factor β-binding protein 4 (1)
- Lateral flow antigen testing (1)
- Lateral flow immunoassay (1)
- Lateral recess stenosis (1)
- Laterality (1)
- Laufökonomie (1)
- Le carcinome épidermoïde oral (1)
- Leadership (1)
- Learning algorithms (1)
- Learning outcomes (1)
- Lebensbedingungen (1)
- Lebenslimitierende Erkrankungen (1)
- Leber (1)
- Leber congenital amaurosis (1)
- Leberkrebs (1)
- Lebermetastase (1)
- Lebertransplantation (1)
- Lectin affinity plasmapheresis (1)
- Lecture (1)
- Lee type, functional outcome (1)
- Lee-type (1)
- Leflunomide (1)
- Left Ventricular Mass (1)
- Left ventricular assist device (1)
- Left ventricular function (1)
- Left ventricular mass (1)
- Left ventricular non-compaction, (1)
- Leg alignment (1)
- Legal considerations (1)
- Legal medicine (1)
- Legasthenie (1)
- Legionella pneumophila (1)
- Lehre im klinischen Alltag (1)
- Lehrerausbildung (1)
- Lehrforschung (1)
- Lehrveranstaltungsevaluation (1)
- Lehrvideos (1)
- Leichenschauschein (1)
- Leigh syndrome (1)
- Leipzig (1)
- Leipzig <2015> (1)
- Leipzig, Universitätskinderklinik (1)
- Leishmaniasis (1)
- Leistungsfähigkeit (1)
- Leistungsmessung (1)
- Leistungsorientierte Mittelvergabe (1)
- Leitbegriff (1)
- Leitlinie (1)
- Leitliniengerechte Behandlung (1)
- Leksell (1)
- Lemperle (1)
- Lenalidomide (1)
- Length of stay (1)
- Lennox-Gastaut syndrome (1)
- Lentiviral vectors (1)
- Lernen (1)
- Lernerfolgsmessung (1)
- Lernziele (1)
- Les macrophages associés aux tumeurs (1)
- Lesestörung (1)
- Leseverstehen (1)
- Lesion (1)
- Leukaemic Cells (1)
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1)
- Leukocyte depletion filter (1)
- Leukocyte elastase (1)
- Leukocytes (1)
- Leukodystrophy (1)
- Leukotriene (1)
- Leukozytenfiltration (1)
- Levobupivacain (1)
- Levobupivacaine (1)
- Liberalismus (1)
- Lice (1)
- Life-limiting conditions (1)
- Lifestyle (1)
- Ligand post-insertion (1)
- Ligatur (1)
- Light sheet fluorescence microscopy (1)
- Limitation of therapy (1)
- Lineage (1)
- Lineage tracing (1)
- Linkage (1)
- Lipedema (1)
- Lipemia (1)
- Lipid Transition Temperature (1)
- Lipid metabolism (1)
- Lipid peroxidation (1)
- Lipid signaling (1)
- Lipid solution (1)
- Lipid trafficking (1)
- Lipidol (1)
- Lipidstoffwechsel (1)
- Lipiodol (1)
- Lipodystrophy (1)
- Lipopolysaccharide-binding protein (1)
- Lipoprotein(a)/Analytik (1)
- Lipoprotein(a)/analysis (1)
- Lipoproteine (1)
- Liposuction (1)
- Lippen-Kiefer-Gaumenspalte (1)
- Lipämie (1)
- Liquid filled MicroLion ion chamber array (1)
- Liquor cerebrospinalis (1)
- Liquordiagnostik (1)
- Lithium (1)
- Liver Fibrosis (1)
- Liver biopsy (1)
- Liver disease (1)
- Liver enzymes (1)
- Liver histology (1)
- Liver metastases (1)
- Liver resection (1)
- Liver transplant (1)
- Liver-Related Complications (1)
- Liver-related complications (1)
- LiverTox (1)
- LncRNA - long noncoding RNA (1)
- Loa loa (1)
- Local IgE (1)
- Local allergic rhinitis (1)
- Local control (1)
- Local field potential (1)
- Localized prostate cancer (1)
- Locally advanced (1)
- Lockdown (1)
- Loco-regional control (1)
- Locomotor circuit (1)
- Lokales IgE (1)
- Lokalisation (1)
- Lomentospora prolificans (1)
- Long interspersed nuclear elements (LINE) (1)
- Long non-coding RNA (1)
- Long noncoding RNA (1)
- Long term output (1)
- Long term result (1)
- Long-COVID (1)
- Long-term (1)
- Long-term continence (1)
- Long-term effect (1)
- Long-term follow up (1)
- Long-term follow-up (1)
- Long-term results (1)
- Long-term-measurements (1)
- Longchain polyunsaturated fatty acids (1)
- Longitudinal Study (1)
- Longitudinal analysis (1)
- Longitudinalstudie (1)
- Low birth weight infant (1)
- Low grade glioma (1)
- Low volume prep (1)
- Low-dose X-irradiation (1)
- Low-dose ionizing radiation (1)
- Low-dose radiation therapy (1)
- Low-grade glioma (1)
- Lower back pain (1)
- Lp(a)-Lipoproteinbestimmungen (1)
- Lp(a)-lipoprotein determinations (1)
- Lpar2 (1)
- Ltbp-4 (1)
- Ltbp-4L (1)
- Ltbp-4S (1)
- Ltbp4 (1)
- Lucigenin (1)
- Luftverkehr (1)
- Lumbar spinal canal stenosis (1)
- Lumbar stenosis (1)
- Lumican (1)
- Luminex (1)
- Lung (1)
- Lung Cancer (1)
- Lung Neoplasms/serum (1)
- Lung adenocarcinoma (1)
- Lung development (1)
- Lung function (1)
- Lung neoplasms (1)
- Lung ultrasound (1)
- Lungenbiopsie (1)
- Lungenerkrankungen (1)
- Lungenherde (1)
- Lungenkontusion (1)
- Lungenneoplasma/Serum (1)
- Lungentumor (1)
- Lungenversagen (1)
- Lyme Borreliosis (1)
- Lyme Disease (1)
- Lyme borreliosis (1)
- Lyme disease - Borreliosis (1)
- Lyme-Borreliose (1)
- Lymph node (1)
- Lymphadenopathy (1)
- Lymphangiectasia (1)
- Lymphangiogenesis (1)
- Lymphangioleiomyomatosis (1)
- Lymphedema (1)
- Lymphocyte (1)
- Lymphocyte subpopulations (1)
- Lymphoepithelioma (1)
- Lymphoid Neoplasia (1)
- Lymphoid tissues (1)
- Lymphoma Cells (1)
- Lymphomas (1)
- Lymphopenia Mortality (1)
- Lymphozytenantigen (1)
- Lynch-Syndrom (1)
- Lysosomal storage disease (1)
- Ländlicher Raum (1)
- M. Intracellulare (1)
- M. avium (1)
- M. avium complex (1)
- M. chimaera (1)
- MACE (1)
- MAGGIC score (1)
- MAIT cell (1)
- MAP Kinases (MAPKs) (1)
- MAP kinase (1)
- MBC (1)
- MC-Fragen (1)
- MCH (1)
- MCP (1)
- MCP-1 (1)
- MDD (1)
- MDM2 (1)
- MDR1 (1)
- MEDIC (1)
- MEIS (1)
- MEIS homeodomain protein (1)
- MEIS2 (1)
- MEK inhibitor (1)
- MELD (1)
- MEN1 (1)
- MET (1)
- MFA (1)
- MGMT (1)
- MGMT promoter (1)
- MIC (1)
- MID task (1)
- MK-0457 (1)
- MKP1 (1)
- ML-IAP (1)
- MLC tracking (1)
- MLL-rearranged leukemia (1)
- MLN8237 (1)
- MLV (1)
- MM-121 (1)
- MMF (1)
- MMP14 (1)
- MMP2 (1)
- MMPs (1)
- MN1 (1)
- MOLLI (1)
- MPA (1)
- MPM (1)
- MPN (1)
- MPN-U (1)
- MR-based histology (1)
- MR-guided (1)
- MR-proADM (1)
- MR-spectroscopy (1)
- MRA (1)
- MRI patterns of gliomas (1)
- MRI-negative epilepsy (1)
- MRP4 (1)
- MS (1)
- MSC (1)
- MSC-subsets (1)
- MSM (1)
- MT: Non-coding RNAs (1)
- MTCL (1)
- MTHFR-Mutation (1)
- MTHFR-mutation (1)
- MTL30 (1)
- MTOR inhibitor (1)
- MTRNR1 (1)
- MTRasym (1)
- MTT (1)
- MUTARS® RS Cup (1)
- MUTARS® RS Cup System (1)
- MUTARS® RS cup system (1)
- MVPA (1)
- MYCBP2 (1)
- MYCN amplification (1)
- Machine Learning (1)
- Machine learning algorithms (1)
- Machine teaching (1)
- Macrophage (1)
- Macrophage Transdifferentiation (1)
- Macular neovascularization (1)
- Magnet dislocation (1)
- Magnetencephalography (1)
- Magnetic resonance imaging (MRI) (1)
- Magnetoencephalographie (1)
- Magnetoencephalography (1)
- Magnetresonanztomografie (1)
- Magnetresonanztomographie (1)
- Maintenance therapy (1)
- Maintenance treatment (1)
- Major Depressive Disorder (1)
- Major bleeding (1)
- Major infection after cardiac surgery (1)
- Makrophage (1)
- Makrophagen (1)
- Malaria prophylaxis (1)
- Malariae (1)
- Malariaprophylaxe (1)
- Malate Dehydrogenases (1)
- Male (1)
- Male Population (1)
- Malignancy (1)
- Malignant meningioma (1)
- MammaPrint (1)
- Mammalian target of rapamycin (1)
- Mammaplasty (1)
- Mammary gland (1)
- Managed Care (1)
- Management (1)
- Manatee invariant (1)
- Manchester scar scale (1)
- Mandatory Vaccinations (1)
- Mandible (1)
- Mandibula (1)
- Mangel (1)
- Mania (1)
- Manuelle Lymphdrainage (1)
- Manufacturing (1)
- Maple bark disease (1)
- Maple bark strippers’ lung (1)
- Mapping (1)
- Marginal grafts (1)
- Marginal integrity (1)
- Marker genes (1)
- Marknagelung (1)
- Markov model (1)
- Masking effect (1)
- Masquelet (1)
- Mass disaster (1)
- Massenkatastrophe (1)
- Massenspektrometrie (1)
- Massive Online Open Course (1)
- Master Plan 2020 (1)
- Masterplan 2020 (1)
- Mastoiditis (1)
- Matching-adjusted indirect comparison (MAIC) (1)
- Material (1)
- Materials science (1)
- Maternal morbidity (1)
- Maternal separation (1)
- Mathematical biosciences (1)
- Mathematical functions (1)
- Mathematical methods (1)
- Mathematical model (1)
- Mathematical models (1)
- Mathematische Biologie (1)
- Maxillofacial reconstruction (1)
- Maxillofacial surgery (1)
- Maxillofacial trauma (1)
- Mcl-1 (1)
- MdM2 (1)
- Mean erythrocyte volume (1)
- Measles (1)
- Measurement equipment (1)
- Mechanical ankle instability (1)
- Mechanical ventilation (1)
- Mechanism of action (1)
- Meckel’s diverticulum (1)
- Median nerve (1)
- Medical (1)
- Medical Education (1)
- Medical Oncology (1)
- Medical communication (1)
- Medical errors (1)
- Medical ethics (1)
- Medical examiner (1)
- Medical history (1)
- Medical hypoxia (1)
- Medical imaging (1)
- Medical implants (1)
- Medical law (1)
- Medical management (1)
- Medical school (1)
- Medical staff (1)
- Medical student (1)
- Medical studies (1)
- Medical study (1)
- Medical traineeship (1)
- Medication changes (1)
- Medicine and health sciences (1)
- Medikamente (1)
- Medikamente Handlungsanweisungen (1)
- Medizin ; Information Retrieval ; World Wide Web ; Medizin ; Metasuchmaschine (1)
- Medizinalrhabarber (1)
- Medizingeschichte, Lehrbuch (1)
- Medizinische Abbildung (1)
- Medizinische Ethik (1)
- Medizinische Fachangestellte (1)
- Medizinische Fehler (1)
- Medizinische Lehre (1)
- Medizinische Psychologie (1)
- Medizinisches Personal (1)
- Medizinkritik in der Literatur (1)
- Medizinrecht (1)
- Medizinsoziologie (1)
- Medizinstudenten 1968 (1)
- Meersseman test (1)
- Mehrfachbefunde (1)
- Mekoniumaspiration (1)
- Membrane Attack Complex (1)
- Membrane Trafficking (1)
- Membrane assays (1)
- Membrane staining (1)
- Membrane-Phloretin Interaction (1)
- Mena/VASP (1)
- Mengele, Josef (1)
- Meningeom (1)
- Meningioma (1)
- Menschenversuche, verbrecherische (1)
- Mental disorder (1)
- Mental health disorders (1)
- Mental health problems (1)
- Mental health therapies (1)
- Menthol (1)
- Mentor (1)
- Mesangial cells (1)
- Mesenchym (1)
- Mesenchymal stem cell (1)
- Mesenchymal stem/stromal cells (1)
- Mesenchymal stromal cells (1)
- Mesenchymal stromal cells (MSC) (1)
- Mesh repair (1)
- Metaanalysis (1)
- Metabolic dysfunction (1)
- Metabolic labeling (1)
- Metabolic models (1)
- Metabolic vulnerabilities (1)
- Metabolism, Inborn Errors (1)
- Metabolomic profile (1)
- Metacognition (1)
- Metal clip (1)
- Metalloproteases (1)
- Metalloproteinases (1)
- Metastase (1)
- Metastasis-directed therapy (1)
- Metastatic tumors (1)
- Metformin (1)
- Methacholine challenge test (1)
- Methacholinprovokation (1)
- Methadon (1)
- Methanol (1)
- Methicillin resistance (1)
- Methicillin-resistenter Staphylococcus aureus (1)
- Methionine (1)
- Method validation (1)
- Methoden (1)
- Methodenvalidierung (1)
- Methodenvergleich (1)
- Methods (1)
- Methotrexate (1)
- Methylation (1)
- Methylmercury Containing Inactivator (1)
- Methylphenidate (1)
- Mgm1p (1)
- MiR-29 (1)
- MiSpEx Network (1)
- MiSpEx-network (1)
- Mice (1)
- Michael acceptor (1)
- Micro RNAs (1)
- Micro computed tomography (1)
- Micro-CT (1)
- MicroRNA-181a (1)
- MicroRNAs (miRNAs) (1)
- Microalgae (1)
- Microarray (1)
- Microbial mutation (1)
- Microbiology and Infectious Disease (1)
- Microbiology, Virology & Host Pathogen Interaction (1)
- Microbubbles (1)
- Microenvironment (1)
- Microfilaremia (1)
- Microfluidics (1)
- Microgap (1)
- Microglial cells (1)
- Micrognathia (1)
- Microparticles (1)
- Microphones (1)
- Microphysiological models (1)
- Microplastic (1)
- Microsatellite instability (1)
- Microstates (1)
- Microstructural impairment (1)
- Microtubule (1)
- Mid-intestinal bleeding (1)
- Midbrain/brainstem expression changes (1)
- Middle East respiratory syndrome coronavirus (1)
- Midkine (1)
- Midline laparotomy (1)
- Midwifery (1)
- Migrant health (1)
- Mikroangiopathie (1)
- Mikroneutralisationstest (1)
- Mikropartikel (1)
- Mikrovesikel (1)
- Mikrowellenablation (1)
- Mild cognitive impairment (1)
- Mild hypoxia (1)
- Mindestmengen (1)
- Mineralization (1)
- Mineralocorticoids (1)
- Mineralokortikoide (1)
- Mini-monovision (1)
- Minimal Residual Disease (MRD) (1)
- Minimal core of imaging (1)
- Minimal invasive (1)
- Minimal invasive dentistry (1)
- Minimal-invasiv (1)
- Minimale Hemmkonzentration (1)
- Minimale bakterizide Konzentration (1)
- Minimally invasive (1)
- Minimally invasive surgical procedures (1)
- Minimally invasive transforaminal interbody fusion (1)
- Minor injury (1)
- Mislocalised proteins (1)
- Mitochondrial Apoptosis (1)
- Mitochondrial Metabolism (1)
- Mitochondrial Permeability Transition (1)
- Mitochondrial Transport (1)
- Mitochondrial amino acid tRNA synthetases (1)
- Mitochondrial and Cytoplasmic Malate Dehydrogenase (1)
- Mitochondrial disease (1)
- Mitochondrial disorder (1)
- Mitochondrial function (1)
- Mitochondrial proteins (1)
- Mitochondrial respiration (1)
- Mitochondrial shuttles (1)
- Mitochondrien (1)
- Mitomycin C (1)
- Mitoxantrone (1)
- Mitral regurgitation (1)
- Mitral valve (1)
- Mitralklappenrekonstruktion (1)
- MixCon (1)
- MixCon-LA (1)
- Mixed Lipid Phases (1)
- Mixed Methods (1)
- Mixed hearing loss (1)
- Mmp12 (1)
- Model Organism (1)
- Model organisms (1)
- Modell-Curriculum (1)
- Modellprojekt, (1)
- Moderating factors (1)
- Moderne Medizin (1)
- Modified FDI criteria (1)
- Molar tooth sign (1)
- Mole-rat (1)
- Molecular Biology (1)
- Molecular Chaperone (1)
- Molecular diagnosis (1)
- Molecular diagnostic testing (1)
- Molecular diagnostics (1)
- Molecular genetics (1)
- Molecular glue (1)
- Molecular imaging (1)
- Molecular marker (1)
- Molecular matched therapy (1)
- Molecular mimicry (1)
- Molecular signatures (1)
- Molecular subtype (1)
- Molecular therapy (1)
- Molecularly targeted therapy (1)
- Molekulare Therapie (1)
- Moll, Albert (1)
- Molmassenverteilung (1)
- Monacolin K (1)
- Monetary incentive delay (1)
- Mongolian spot (1)
- Monoacylglycerol lipase (1)
- Monoclonal antibodies (1)
- Monoclonal antibody (mAb) (1)
- Monocyte gene expression (1)
- Monocytes and macrophages (1)
- Monolithic crown (1)
- Monosaccharide Transport Proteins (1)
- Monotherapie (1)
- Monozyt (1)
- Monozyten (1)
- Monte Carlo method (1)
- Monte Carlo simulation (1)
- Mood (1)
- Morbidität (1)
- Morbus Crohn (1)
- Morbus Cushing Syndrom (1)
- Morphin (1)
- Morphological modeling (1)
- Morphologie (1)
- Morris Hepatoma (1)
- Mortalitätskorrektur (1)
- Mortaliät (1)
- Mosquito (1)
- Mosquito crop (1)
- Mosquito-plant interaction (1)
- Motility (1)
- Motility disorder (1)
- Motivating factor (1)
- Motivation (1)
- Motivational situation (1)
- Motivationslage (1)
- Motor neuron disease (1)
- Motor skills (1)
- Motor-cognitive (1)
- Mouse model (1)
- Moviprep (1)
- Mu-opioid receptor (1)
- Mucomaix® matrix (1)
- Mucopolysaccharidoses (1)
- Mukoviszidose (1)
- Multi-Omics (1)
- Multi-center (1)
- Multi-modal feedback (1)
- Multi-motive grid (1)
- Multi-nucleated cardiomyocytes (1)
- Multi-resistant pathogens (1)
- Multi-stakeholder approach (1)
- Multi-syndrome classification (1)
- Multidetector Computed Tomography (1)
- Multidisciplinary management (1)
- Multidrug-resistance (1)
- Multidrug-resistant bacteria (1)
- Multidrug-resistant organisms (1)
- Multidrug-resistant tuberculosis (1)
- Multilevel two-part modelling (1)
- Multiligament instability (1)
- Multimedia (1)
- Multimedication (1)
- Multimodal Modeling (1)
- Multimodal imaging (1)
- Multimorbid patients (1)
- Multimorbilidad (1)
- Multinomial logistic regression (1)
- Multinucleated giant cells (1)
- Multiomics (1)
- Multiparametric MRI (1)
- Multiple Sclerosis (1)
- Multiple Transport Systems (1)
- Multiple choice Fragen (1)
- Multiple myeloma (1)
- Multiple trauma (1)
- Multiple-indication review (1)
- Multiplex immunoassay (1)
- Multiresistente Erreger (1)
- Multisensorische Integrationsleistung (1)
- Multisensory (1)
- Multiset independent component analysis (1)
- Multivariate Analyse (1)
- Mundhöhlenkarzinome (1)
- Muscarinic acetylcholine receptor (1)
- Muscle (1)
- Muscle analysis (1)
- Muscle atrophy (1)
- Muscle damage (1)
- Muscle pain (1)
- Muscle tissue (1)
- Muscular diseases (1)
- Musculoskeletal (1)
- Musculoskeletal abnormalities (1)
- Musculoskeletal mechanics (1)
- Musculoskeletal problems (1)
- Musculoskeletal ultrasound (1)
- Music (1)
- Music chair concepts (1)
- Musical rhythm (1)
- Musician (1)
- Musician-specific seating position (1)
- Muskuloskeletales System (1)
- Muskuloskelettale Erkrankungen (1)
- Mutation databases (1)
- Muttermilch (1)
- Mycobacteria (1)
- Mycobacterium avium complex (1)
- Mycophenolat Mofetil (1)
- Mycophenolate mofetil (1)
- Mycophenolatmofetil (1)
- Mycoses (1)
- Mycosis (1)
- Myelin or myeloarchitecture (1)
- Myelodysplastic syndrome (1)
- Myelofibrosis (1)
- Myeloperoxidase (1)
- Myeloproliferative disease (1)
- Myiasis (1)
- Mykose (1)
- Myocardial infarction (MI) (1)
- Myocardial injury (1)
- Myocardial remodeling (1)
- Myocardial revascularization (1)
- Myocardial segmentation (1)
- Myocarditis (1)
- Myokardinfarkt (1)
- Myonecrosis (1)
- Myotonic dystrophy (1)
- Männerstimme (1)
- Müdigkeit (1)
- München <2011> (1)
- Mφs (1)
- N-Acetylaspartate (1)
- N-acetyl-L-cysteine (1)
- N-acetylcysteine (1)
- N-cadherin (1)
- N-cadhérine (1)
- N-glycosylation (1)
- N-hydroxysuccinimide (1)
- N-methyl-D-aspartate receptor (1)
- N-myc (1)
- N2 (1)
- N471D strumpellin knock-in mice (1)
- N501Y (1)
- NAD + Analogues (1)
- NAD Analogs (1)
- NAD+-Analogs (1)
- NADP+ Analogues (1)
- NADPH oxidase 4 (1)
- NAD⊕-Isomer (1)
- NAFL (1)
- NAPS (1)
- NAT (1)
- NCAM (1)
- NCH93 (1)
- NCOA4 (1)
- NDBI (1)
- NDM (1)
- NDNF interneurons (1)
- NDR1 (1)
- NDUFA6 (1)
- NDUFAF8 (1)
- NEAT1 (1)
- NEAT2 (1)
- NET (1)
- NETs (1)
- NF-kB (1)
- NF-ĸB (1)
- NF-кB (1)
- NFAT (1)
- NFkB (1)
- NGS (1)
- NGS sequencing (1)
- NHE (1)
- NHEJ (1)
- NIS (1)
- NK Receptor (1)
- NK cell subset (1)
- NK cell subsets (1)
- NK receptors (1)
- NK-ZELL-BASIERTER IMMUNTHERAPIE (1)
- NK-ZELLEN (1)
- NK-Zellen (1)
- NK-cells (1)
- NKG2A blocking (1)
- NKT cell (1)
- NLPHL (1)
- NLRP3 inflammasomes (1)
- NMDA IgA/IgM antibodies (1)
- NMDA antibody (1)
- NMDAR subunit GluN2B (1)
- NMO-IgG (1)
- NMOSD (1)
- NOD (1)
- NOD2 (1)
- NOS (1)
- NOS-I (1)
- NOS1AP (1)
- NOXA (1)
- NPC disease (1)
- NPH insulin (1)
- NPSR1 (1)
- NR4A2 (1)
- NR4A3 (1)
- NRAS (1)
- NS-Kindereuthanasie (1)
- NS1608 (1)
- NS3 protease inhibitor (1)
- NS3-4A protease inhibitor (1)
- NS3/4A protease inhibitors (PI) (1)
- NS3/4A-Protease (1)
- NS5A inhibitors (1)
- NS5B polymerase inhibitor (1)
- NSAIDs (1)
- NSBB (1)
- NSC350625 (1)
- NSE (1)
- NSF (1)
- NSG mice (1)
- NSTEMI (1)
- NTDs (1)
- NTM (1)
- NURF (1)
- NVBP (1)
- NXF1 (1)
- Nachteile (1)
- Nachtschattengewächs (1)
- Nachwuchsmangel (1)
- Nackenmuskulatur (1)
- Nackenschmerzen (1)
- Nahrungsmittelhygiene (1)
- NanoBone (1)
- Nanocrystalline (1)
- Nanoparticles (1)
- Nanoplastic (1)
- Nanopore (1)
- Nasenpolyp (1)
- Nasenschleimhaut (1)
- Nateglinide (1)
- National catalogue of competence-based learning objectives in dentistry (1)
- Native T1 (1)
- Native T1 mapping (1)
- Natriuretic peptide (1)
- Natural Killer (NK) Cell (1)
- Natural killer cells (1)
- Naturwissenschaften (1)
- Nav channel activity (1)
- Nav1.7 (1)
- Nebennierenrinden-Adenom (1)
- Nebennierenrinden-Hyperplasie (1)
- Neck muscles (1)
- Neck pain (1)
- Necroptosis (1)
- Necrosis (1)
- Necrosis (Necrotic Death) (1)
- Necrotic area (1)
- Necrotizing fasciitis (1)
- Needs Assessment [MeSH] (1)
- Needs assessment [MeSH] (1)
- Negative appendectomy rate (1)
- Negative staining (1)
- Negative-pressure wound therapy (1)
- Neglected tropical diseases (1)
- Negligence (1)
- Nek1 (1)
- Nekrose (1)
- Neoadjuvant radiochemotherapy (1)
- Neoadjuvant systemic therapy (1)
- Neoadjuvant therapy (1)
- Neoadjuvant treatment (1)
- Neonatal (1)
- Neonatal abstinence syndrome (1)
- Neonatal brain damage (1)
- Neonatal intensive care unit (1)
- Neonatal morbidity (1)
- Neonatal outcome (1)
- Neonatal surgery outcome (1)
- Neonatal urea cycle disorders (1)
- Neonatales Entzugssyndrom (1)
- Neonatologie (1)
- Neosexualitäten (1)
- Nephelometrie und Turbidimetrie (1)
- Nephelometry and Turbidimetry (1)
- Nephrogenese (1)
- Nephrons (1)
- Nephropathie (1)
- Nervenkrankheit (1)
- Nerves (1)
- Nervous system diseases (1)
- Nesplora Aquarium (1)
- Network Neuroscience (1)
- Network analysis (1)
- Network model (1)
- Netzhaut (1)
- Neues Steuerungsmodell (1)
- Neugeborene (1)
- Neugeborenen-Hörscreeningverfahren ; DPOAE- und AABR-Messungen ; Gerätevergleich ABaer und Ero-Scan (1)
- Neural coding (1)
- Neural function (1)
- Neural goal function (1)
- Neural networks (1)
- Neuro-ophthalmology (1)
- NeuroSAFE (1)
- Neurobiology of disease and regeneration (1)
- Neuroblastom, SAMHD1, Chemoresistenz (1)
- Neuroblastoma (1)
- Neurochemistry (1)
- Neurodegenerative diseases (1)
- Neurodegenerative syndromes (1)
- Neurodevelopment (1)
- Neurodevelopmental disorder (1)
- Neurodevelopmental disorders (1)
- Neuroendocrine cancer (1)
- Neuroendocrine tumor (1)
- Neuroepithelial (1)
- Neuroepithelial tumor (1)
- Neurofeedback (1)
- Neurofilament light chain (1)
- Neurofilament light chains (1)
- Neurofilament-Leichtketten (1)
- Neurogenese (1)
- Neurogenesis (1)
- Neuroligins (1)
- Neurologe (1)
- Neurologiegeschichte (1)
- Neurologisches Institut <Frankfurt am Main> (1)
- Neuromodulatorisches Netzwerk (1)
- Neuromodulatory network (1)
- Neuromuscular exercise (1)
- Neuromyelitis optica (1)
- Neuron-Specific Enolase/serum (1)
- Neuron-spezifische Enolase/Serum (1)
- Neuronal dendrites (1)
- Neuronal homeostasis (1)
- Neuronal networks (1)
- Neuronal nitric oxide synthase (1)
- Neuronal plasticity (1)
- Neuronales Netzwerk (1)
- Neuronavigation (1)
- Neuronspecific Enolase (1)
- Neuronspezifische-Enolase (1)
- Neurooncology (1)
- Neuropathic pain (1)
- Neuropathie (1)
- Neuropathologie (1)
- Neurophysiologie (1)
- Neurophysiology (1)
- Neuropilin (1)
- Neuropsychiatric disorders (1)
- Neuropsychiatrie (1)
- Neuropsychological testing (1)
- Neuropsychologie (1)
- Neuropsychology (1)
- Neurostimulation (1)
- Neurovascular damage (1)
- Neurovascular lesion (1)
- Neurowissenschaften (1)
- Neutrophils (1)
- Nevus of Ito (1)
- Nevus of Ota (1)
- New Developments (1)
- New E3-ligase ligands (1)
- Newbornhearingscreening (1)
- Next generation sequencing (1)
- NfL (1)
- Nfe2l2 (1)
- Niche (1)
- Niche differentiation (1)
- Nicht-allergische Rhinitis (1)
- Nichtversicherung (1)
- Nicolaides-Baraitser syndrome (1)
- Nicotine (Nicotiana tabacum/ Nicotiana rustica) (1)
- Nicotinic acetylcholine receptors (1)
- Nierendosimetrie (1)
- Nikotin (Nicotiana tabacum/ Nicotiana rustica) (1)
- Nikotinerge Acetylcholinrezeptoren (1)
- Nimotuzumab (1)
- Nitric Oxide Synthase (1)
- Nkx2-5 (1)
- Nociception (1)
- Nodular lymphocyte predominant Hodgkin lymphoma (1)
- Non-Hodgkin Lymphoma (1)
- Non-Hodgkin lymphoma (1)
- Non-Hodgkin-Lymphom (1)
- Non-RCT (1)
- Non-abusive head trauma (NAHT) (1)
- Non-alcoholic fatty liver disease (1)
- Non-allergic-rhinitis (1)
- Non-aneurysmal (1)
- Non-apoptotic functions (1)
- Non-clear cell renal cell cancer (1)
- Non-coding RNAs (1)
- Non-cylindrical folds (1)
- Non-diffractive EDOF-IOL (1)
- Non-expert MRI (1)
- Non-falciparum (1)
- Non-invasive brain stimulation (1)
- Non-neuronal cholinergic system (1)
- Non-nucleoside polymerase inhibitors (NNI) (1)
- Non-operative (1)
- Non-perimesencephalic (1)
- Non-responder (1)
- Non-small-cell lung cancer (1)
- Non-steroidal anti-inflammatory drugs (1)
- Non-trauma (1)
- Non-tuberculous mycobacteria (1)
- Non-urothelial (1)
- Non-vitamin K antagonist oral anticoagulants (1)
- Nonaerosolizing treatment (1)
- Noncoding RNA (1)
- Nonfermenter (1)
- Noninferiority (1)
- Nonoperative management (1)
- Nonpenetrating (1)
- Nonsteroidal anti-inflammatory drugs (1)
- Nontuberculous mycobacteria (1)
- Nonunion (1)
- Non–small-cell lung cancer (1)
- Noradrenergic (1)
- Nordhrine-Westfalia (1)
- Nordic questionnaire (1)
- Nordrhein-Westfalen (1)
- Norepinephrine (1)
- Normalkollektiv (1)
- Normative modeling (1)
- Notch (1)
- Notch signaling (1)
- Notfallausweis (1)
- Notfallmedizin (1)
- Notfallversorgung (1)
- Novel treatment target (1)
- Nox inhibition (1)
- NoxA1 (1)
- Nrf-2 (1)
- Nucleolus (1)
- Nucleophosmin-1 (1)
- Nucleotide Triphosphate Analogue (1)
- Nucleus pulposus cells (1)
- Nukleinsäure-Amplifikationstechnik (NAT) (1)
- Nukleinsäureamplifikationstest (NAT) (1)
- Nuklid (1)
- Null responder (1)
- Number of platelets (1)
- Numerical simulation (1)
- Nurses (1)
- Nursing (1)
- Nutrition risk stratification (1)
- Nymphs (1)
- O-GlcNAcylation (1)
- OA (1)
- OECD performance standards (1)
- OGR1 (1)
- OGTT (1)
- OHIP-G14 (1)
- OHRQoL (1)
- ONC201 (1)
- OP capacity (1)
- OP-Kapazität (1)
- OPRM1 methylation (1)
- OPS (1)
- OR time (1)
- ORES (1)
- ORIS (1)
- ORL (1)
- ORP (1)
- OSA (1)
- OSF-2 KI-S2 (1)
- OTSC Proctology (1)
- OTU domain-containing protein 7B (OTUD7B) (1)
- OXA-23 (1)
- OXA-484 (1)
- OXA-58 (1)
- OXPHOS (1)
- Oberarmbruch (1)
- Oberflächenantigen-Mutante (1)
- Object perception (1)
- Object vision (1)
- Objectives (1)
- Objektivität (1)
- Observational studies (1)
- Obsessive-compulsive disorder (1)
- Obstetric care (1)
- Obstetrics (1)
- Obstruktive Bronchitis (1)
- Occlusion (1)
- Occupational Accidents (1)
- Occupational exposure (1)
- Occupational medicine (1)
- Occupational reintegration management (1)
- Occupationally acquired infection (1)
- Ocular findings (1)
- Ocular tuberculosis (1)
- Oesophageal cancer (1)
- Oesophagogastric cancer oxaliplatin (1)
- Off-pump surgery (1)
- Office work (1)
- Ohnr (1)
- Ohrenheilkunde (1)
- Ohrenkrankheit (1)
- Okinawa (1)
- Okinawa diet (1)
- Older adult (1)
- Older adults (1)
- Older patient (1)
- Older patients (1)
- Oldest-old (1)
- Olfactory diagnostics (1)
- Olfactory groove meningioma (1)
- Oligodendrogliom (1)
- Oligodendroglioma (1)
- Oligometastatic (1)
- Omega lipids (1)
- Omega-3-Fettsäuren (1)
- Omicron variant BA.1 (1)
- Omics (1)
- Omphalocele (1)
- Omphalozele (1)
- Oncogenes (1)
- Oncologic surgery (1)
- Oncolytic adenovirus (1)
- Oncolytic virus (1)
- Oncotargets (1)
- One health (1)
- One-leg stand (1)
- Onkogene (1)
- Onkologie (1)
- Onkomodulation (1)
- Online Survey (1)
- Online education (1)
- Online-Lehre (1)
- Online-Lernen (1)
- Online-Magazin (1)
- Online-Magazine (1)
- Online-Umfrage (1)
- Opacity (1)
- Open Science (1)
- Open abdomen (1)
- Open pulmonary tuberculosis (1)
- Open source concept (1)
- Operationsvorbereitung (1)
- Ophthalmoplegia (1)
- Opiatrezeptor (1)
- Opinion (1)
- Opioid system (1)
- Oposterior urethral valve (1)
- Oppositional defant disorder (1)
- Oppositional defiant disorder (1)
- Optic nerve atrophy (1)
- Optical coherence tomography angiography (1)
- Optical lenses (1)
- Optical phenomena (1)
- Optisches Signal (1)
- Oral Health Impact Profile (OHIP) (1)
- Oral and maxillofacial surgery (1)
- Oral and maxillofacial trauma (1)
- Oral cancer (1)
- Oral food challenge (1)
- Oral immunotherapy (OIT) (1)
- Oral implantology (1)
- Oral therapy (1)
- Orale Antikoagulanzien (1)
- Orbital fracture (1)
- Orexin (1)
- Organ allocation (1)
- Organ failure (1)
- Organ injury (1)
- Organ motion (1)
- Organ rinse (1)
- Organ shortage (1)
- Organ support (1)
- Organ-confined (1)
- Organoids (1)
- Organs at Risk (1)
- Oroantral communication (1)
- Orphan disease (1)
- Orthodontic tooth movement (1)
- Orthodontist (1)
- Ortspezifische Mutagenese (1)
- Oryctolagus cuniculus (1)
- Oscillating saws (1)
- Osimertinib (1)
- Osmosensing (1)
- OspE (1)
- Ossifying fibroma (1)
- Osteoarthritis (1)
- Osteocalcin (1)
- Osteoinduction (1)
- Osteonecrosis (1)
- Osteoporose (1)
- Osteoporosis diagnosis (1)
- Osteoporotic fractures (1)
- Oswestry Disability Score (1)
- Otorhinolaryngological (1)
- Otorhinolaryngology (1)
- Outcome assessment [MeSH] (1)
- Ovale (1)
- Ovarian cancer treatment (1)
- Ovarian carcinoma (1)
- Ovarielle Reserve (1)
- Ovartoxizität (1)
- Over-the-scope clip (1)
- Overall survival (1)
- Overweight (1)
- Overwintering (1)
- Oxa1/YidC/Alb3 Membrane Insertases (1)
- Oxaliplatin (1)
- Oxidative phosphorylation (1)
- Oxygen (1)
- Oxygen consumption (1)
- Oxygen extraction fraction (1)
- Oxygen uptake (1)
- Oxygen-derived free radicals (1)
- P-gp (1)
- P1NP (1)
- PACS (1)
- PAD-test (1)
- PAI-1 (1)
- PAM (1)
- PAPR (1)
- PAR (1)
- PARK4 (1)
- PARK6 (1)
- PARK7 (1)
- PATZ1 (1)
- PAX3/FOXO1 (1)
- PBBM (1)
- PBM (1)
- PBMC (peripheral blood mononuclear cells) (1)
- PBPK simulation (1)
- PBSC (1)
- PBX (1)
- PBX1 (1)
- PC12 cells (1)
- PC12 neuronal differentiation (1)
- PC20 (1)
- PCP (1)
- PCSK9 protein (1)
- PCV (1)
- PD-1 inhibitor (1)
- PD20 (1)
- PDCD4 (1)
- PDD - Assessment - Screening (1)
- PDE inhibition (1)
- PDE‐5‐inhibitor (1)
- PDI (1)
- PDK1 (1)
- PDPK1 (1)
- PEA-15 (1)
- PEGylated PLGA (PLGA-PEG) (1)
- PEI (1)
- PELICAN (1)
- PEM-technology (1)
- PF-06273340 (1)
- PFL (1)
- PFOA (1)
- PFOS (1)
- PGC-1α (1)
- PGE2 (1)
- PHGDH (1)
- PHR1 (1)
- PI3K inhibitor (1)
- PI3K/mTor inhibition (1)
- PID prevalence (1)
- PIF pocket (1)
- PKA (1)
- PKCδ (1)
- PKCε (1)
- PKD (1)
- PKD/IC (1)
- PLA (1)
- PLAGL1 (1)
- PLK1 (1)
- PLK1 inhibitors (1)
- PLX4032 (1)
- PLX4720 (1)
- PM (1)
- PMA (1)
- PMF (1)
- PMI (1)
- PMMA (1)
- POCT (1)
- POLG (1)
- POR (1)
- PPAR (1)
- PPAR (Peroxisome proliferator-activated receptors) (1)
- PPAR-γ (1)
- PPARγ (1)
- PPTC7 (1)
- PRG-1 (1)
- PRG5 (1)
- PRLTS3 (1)
- PROM (1)
- PROMISE (1)
- PRRT (1)
- PRRT2 (1)
- PRoMPT (1)
- PSA screening (1)
- PSA-Screening (1)
- PTCH (1)
- PTCH-1 (1)
- PTDM (1)
- PTEN inducible kinase 1 (1)
- PTEN p53 Survivin (1)
- PTK2B (1)
- PTM (1)
- PTP-1B (1)
- PTSD (1)
- PUMA (1)
- PV (1)
- PV loop (1)
- PWI (1)
- PXA (1)
- PYGL (1)
- PacBio SMRT sequencing (1)
- Paediatric Investigation Plan (1)
- Paediatric cancer (1)
- Paediatric oncology (1)
- Paediatric research (1)
- Paediatric trauma patients (1)
- Paediatrics (1)
- Pain prevalence (1)
- Pain scale MWA (1)
- Pain sensation (1)
- Palacos reaction (1)
- Palliative Care [MeSH] (1)
- Palmitoylethanolamid (1)
- Pancreas transplantation (1)
- Pancreatic islet (1)
- Pancreatic surgery (1)
- Pancreatitis (1)
- Pancreatoduodenectomy (1)
- Panel testing (1)
- Panic disorder (1)
- Papillon-Lefèvre syndrome (1)
- Par-4 (1)
- Paracelsus, Asteroid (1)
- Paracetamol (1)
- Paracoccus denitrificans (1)
- Parainfluenza (1)
- Paramyxoviridae (1)
- Paraneoplastic syndrome (1)
- Parapneumonic pleural effusion (1)
- Parasympathetic (1)
- Parent support (1)
- Parkinson (1)
- Parkinson diagnosis (1)
- Parkinsonerkrankung (1)
- Parkinsons disease (1)
- Parodontitis (1)
- Parodontitistherapie (1)
- Particle load reduction (1)
- Particle number size distribution (1)
- Particle size distribution (1)
- Particle toxicity (1)
- Particles (1)
- Particulates (1)
- Passivrauch (1)
- Patellarerkrankungen (1)
- Patellofemoral Joint (1)
- Pathogen reduction (1)
- Pathogenicity (1)
- Pathogens (1)
- Pathologic changes (1)
- Pathological complete response (1)
- Pathologists (1)
- Pathology Section (1)
- Pathophysiology (1)
- Patient Blood Management (PBM) (1)
- Patient Outcome Assessment (1)
- Patient Outcome Assessment [MeSH] (1)
- Patient Reported Outcome Measures [MeSH] (1)
- Patient and public Involvement (1)
- Patient care (1)
- Patient care planning (1)
- Patient education (1)
- Patient information (1)
- Patient information materials (1)
- Patient isolation (1)
- Patient knowledge (1)
- Patient outcome assessment (1)
- Patient participation (1)
- Patient perspective (1)
- Patient portals (1)
- Patient preferences (1)
- Patient reported outcomes (1)
- Patient satisfaction (1)
- Patient*inneninformation (1)
- Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (1)
- Patient-centered care (1)
- Patient-reported outcomes (1)
- Patienten (1)
- Patientenaufklärung (1)
- Patientenportale (1)
- Patientensicherheit (1)
- Patientenstudie (1)
- Patientenverfügung (1)
- Pattern recognition receptors (1)
- Pause (1)
- Pdgfrβ (1)
- Pedagogue (1)
- Pediatric burn injury (1)
- Pediatric fracture (1)
- Pediatric neuroimaging (1)
- Pediatric oncology (1)
- Pediatric sarcoma (1)
- Pediatric stem cell transplantation (1)
- Pediatric surgery (1)
- Pediatrics [MeSH] (1)
- Peer Teaching (1)
- Peer teaching (1)
- Peer-feedback (1)
- Peer-teaching (1)
- Peg3 (1)
- Pegylated liposomal doxorubicin (1)
- Pelargonium sidoides questionable hepatotoxicity (1)
- Pelvic (1)
- Pentose Pathway (1)
- Peptides and proteins (1)
- Per1−/−-mice (1)
- Perceived stigma (1)
- Percutaneous (1)
- Percutaneous endoscopic gastrostomy (1)
- Percutaneous pinning (1)
- Percutaneous ultrasound (1)
- Performance (1)
- Performing Artists (1)
- Peri-implant disease (1)
- Pericardial effusion (1)
- Pericarditis (1)
- Perifolliculitis capitis abscedens et suffodiens (1)
- Perilymph (1)
- Perimesencephalic (1)
- Perinatalzentren (1)
- Periodic (1)
- Periodontal disease (1)
- Periodontal diseases (1)
- Periodontal trauma (1)
- Periodontitis grades B and C (1)
- Peripheral arterial occlusive disease (1)
- Peripheral blood smears (1)
- Peripheral vascular disease (1)
- Periphere arterie (1)
- Periprocedural anticoagulation (1)
- Peritoneal macrophages (1)
- Peritumoural oedema (1)
- Peri‑implantitis (1)
- Perkutane transluminale Angioplastie (1)
- Peroxidase (1)
- Perrault syndrome (1)
- Persistence SARS-CoV-2 antibodies (1)
- Persistent organic pollutants (1)
- Persistierender Ductus arteriosus (1)
- Personal medicine (1)
- Personal protective equipment (1)
- Personal stigma (1)
- Personalbelastung (1)
- Personalised medicine (1)
- Personality (1)
- Personality disorder (1)
- Personality inventory (1)
- Personalized Medicine (1)
- Personalmangel (1)
- Personnel shortage (1)
- Perspective forum (1)
- Perspektivforum (1)
- Persönlichkeitsfaktor (1)
- Pertussis (1)
- Pessar (1)
- Peutz–Jeghers syndrome (1)
- Peyronie's disease (1)
- Pfannenstiel (1)
- Pflege (1)
- Pflegeeinrichtungen (1)
- Pgrmc1 (1)
- Phalangeal fractures (1)
- Phantom study (1)
- Phantoms (imaging) (1)
- Pharm-fMRI (1)
- Pharmaco-nutrition (1)
- Pharmacodynamic (1)
- Pharmacokinetics (1)
- Pharmacological treatment (1)
- Pharmacometrics (1)
- Pharmacotherapy (1)
- Pharmacovigilance (1)
- Pharmacy setting (1)
- Pharmaka (1)
- Pharmakoepidemiologie (1)
- Pharyngeal reflex (1)
- Phase 2 (1)
- Phase 3 (1)
- Phase 3 trial (1)
- Phase I clinical trial (1)
- Phase I trials (1)
- Phase II trial (1)
- Phase rotors (1)
- Phase-IV research (1)
- Phase-Proteine (1)
- Phase-reset (1)
- Phenotypic plasticity (1)
- Phenprocoumon (1)
- Phenylketonuria (PKU) (1)
- Philadelphia Chromosome (1)
- Philadelphia Chromosome-positive leukemia (1)
- Philadelphia chromosome-positive acute leukemia (1)
- Philemon and Baucis (1)
- Philemon und Baucis (1)
- Phlyctenule (1)
- Phospho-soda (1)
- Phospho-tau (1)
- Phosphohydrolases (1)
- Phospholipasen A2 (1)
- Phospholipids (1)
- Phosphopyruvate Hydratase/serum (1)
- Phosphopyruvathydratase/Serum (1)
- Phosphorylierung (1)
- Photoaffinity Labeling (1)
- Physical and mental health (1)
- Physical comorbidities (1)
- Physical fitness (1)
- Physical self-perception (1)
- Physical therapist (1)
- Physician report (1)
- Physician-assisted suicide (1)
- Physics (1)
- Physiologie (1)
- Physiotherapy (1)
- Phytochemicals (1)
- Piercing (1)
- Pierre Robin sequence (1)
- Pill Count (1)
- PillCamColon2 (1)
- Pilocytic astrocytoma (1)
- Pilze (1)
- Pilzsinusitis (1)
- Pim-1 (1)
- Pindar, Pythische Ode III (1)
- Pink esthetic score (1)
- Placental growth factor (1)
- Placental organoids (1)
- Planning target volume (1)
- Plantagearbeiter (1)
- Plantation workers (1)
- Plaque <Medizin> (1)
- Plasma fibronectin (1)
- Plasma proteins (1)
- Plasma transfusion (1)
- Plasma usage (1)
- Plasmacytoid dendritic cell (1)
- Plasmapools (1)
- Plasmaprotein analyzer (1)
- Plasmaproteinanalysensysteme (1)
- Plasmaproteinbestimmung im Harn (1)
- Plasmaproteine (1)
- Plasmapräparate (1)
- Plasminogen (1)
- Plastic endoprosthesis (1)
- Plastic pollution (1)
- Plastics (1)
- Plastikstent (1)
- Platelet (1)
- Platelet dysfunction (1)
- Platelet lysate (1)
- Platelet releasate (1)
- Platzierung (1)
- Plausibilität (1)
- Play (1)
- Pleasure (1)
- Plectin (1)
- Plethysmographie (1)
- Pleural empyema (1)
- Plk1 (1)
- Plus-end (1)
- Plättchen-Leukozyten-Aggregate (1)
- Plättchenaktivierung (1)
- Pneumococcal conjugate vaccine (1)
- Pneumothorax (1)
- Poe, Der wahre Sachverhalt im Falle Valdemar (1)
- Point of care (1)
- Point-of-Care Testing (POCT) (1)
- Point-of-care wound diagnostics (1)
- Polarisierung (1)
- Polarity index (1)
- Poliomyelitis (1)
- Polioviren (1)
- Polizei (1)
- Polo-like kinase 3 (1)
- Poly-Pore (1)
- PolySUMOylation (1)
- Polyenfettsäuren (1)
- Polygenic risk score (1)
- Polyhexanide (1)
- Polymerase Chain Reaction (1)
- Polymerase Chain Reaction (PCR) (1)
- Polymerase Kettenreaktion (PCR) (1)
- Polymerase-Kettenreaktion (1)
- Polymerasekettenreaktion (1)
- Polymorphismen (1)
- Polyposis (1)
- Polyposis syndrome (1)
- Polyps (1)
- Polysomnography (1)
- Polyunsaturated fatty acid mediators (1)
- Polyunsaturated fatty acids (1)
- Polyzystisches Ovarsyndrom (1)
- Política de Saúde (1)
- Ponatinib (1)
- Pooling (1)
- Poor solubility (1)
- Population dynamics (1)
- Population-based screening (1)
- Porin regulation (1)
- Porphyromonas gingivalis (1)
- Portal (1)
- Portugal (1)
- Portuguese population (1)
- Posaconazole serum level (1)
- Position paper (1)
- Positron emission tomography (1)
- Positron-emission tomography (1)
- Post mortem examination (1)
- Post mortem interval (1)
- Post surgery pain (1)
- Post treatment (1)
- Post-cesarean (1)
- Post-mortem genetic screening (1)
- Post-offence drinking (1)
- Post-thaw recovery (1)
- Post-transplant (1)
- Post-traumatic stress disorder (1)
- Posterior Cerebral (1)
- Postmortem (1)
- Postmortem interval (1)
- Postoperative Complications (1)
- Postoperative anatomy (1)
- Postoperative infections (1)
- Postoperative nutritional management (1)
- Posttranslational modification (1)
- Posttraumatische Belastungsstörung (1)
- Postural sway (1)
- Posture (1)
- Postvention (1)
- Potassium channel Kir2.1 (1)
- Potassium iodide (1)
- Powered air-purifying respirator (1)
- Practical training (1)
- Practice (1)
- Practice-based Research Network (1)
- Practice-based research network (1)
- Praeklampsie (1)
- Praktikum (1)
- Praktische Fertigkeiten (1)
- Praktische Lehre (1)
- Praktisches Jahr (1)
- Pre-economic effects (1)
- Pre-emptive immunotherapy (1)
- Pre-operative radiotherapy (1)
- Pre-treatment drug resistance mutations (1)
- PreS1 deletion (1)
- Precision (1)
- Precision medicine (1)
- Precision oncology (1)
- Preclinical (1)
- Preclinical drug development (1)
- Precompetitive development (1)
- Prediction of locoregional recurrence (1)
- Predictive Modeling (1)
- Predictive medicine (1)
- Predictive model (1)
- Predictive processing (1)
- Predictors (1)
- Prenatal ultrasonographic detection rate (1)
- Preoperative diagnostics (1)
- Preoperative radiochemotherapy (1)
- Prepontine (1)
- Presbyopia (1)
- Pressure distribution (1)
- Pressure measuring plate (1)
- Pressure pain (1)
- Presynaptic vesicles (1)
- Pre‐Ligand Assembly Domain (PLAD) (1)
- Primary Care Health Centre (1)
- Primary Care Research Network (1)
- Primary breast lymphoma (1)
- Primary health care [MeSH] (1)
- Primary molars (1)
- Primary prophylaxis (1)
- Primary sclerosing cholangitis (1)
- Principal component analysis (1)
- Private Krankenversicherung (1)
- Pro.M.D. (1)
- Probenidentifikation (1)
- Procedural skills (1)
- Produkte zur Desinfektion (1)
- Professional dance (1)
- Professional dancers (1)
- Professioneller Fußball (1)
- Professions (1)
- Profi-Tänzer*innen (1)
- Proficiency testing (1)
- Profiling Transthiolation Activity (1)
- Profilometry (1)
- Progestatifs synthétiques (1)
- Progesteron (1)
- Progesterone (1)
- Prognose (1)
- Prognostic biomarker (1)
- Prognostic models (1)
- Prognostische Marker (1)
- Programming languages (1)
- Projekte Seltene Erkrankungen (1)
- Promoters (1)
- Promotor <Genetik> (1)
- Propensity score matching (1)
- Propensity-Score Matching Analyse (1)
- Proposal (1)
- Propriozeption (1)
- Prospective randomized Analysis (1)
- Prostaglandin (1)
- Prostaglandin D2 (1)
- Prostaglandin E2 (1)
- Prostaglandine (1)
- Prostata-specific antigen (1)
- Prostataarterienembolisation (1)
- Prostatakrankheit (1)
- Prostatakrebs (1)
- Prostate Cancer (1)
- Prostate cancer cell lines (1)
- Prostate-specific membrane antigen (1)
- Prostatic specific antigen (1)
- Prosthetic rehabilitation (1)
- Protease activity (1)
- Proteasomes (1)
- Protective factors (1)
- Protein (1)
- Protein Domains (1)
- Protein Expression (1)
- Protein Folding (1)
- Protein Kinase Inhibitors (1)
- Protein Motifs (1)
- Protein Structure (1)
- Protein Targeting (1)
- Protein aggregates (1)
- Protein complex (1)
- Protein degradation (1)
- Protein domains (1)
- Protein interactions (1)
- Protein kinase (1)
- Protein purify derivative (1)
- Protein tyrosine modification (1)
- Protein-Kinasen (1)
- Protein-Lipid Interaction (1)
- Protein-Tyrosin-Kinasen (1)
- Protein-translocation (1)
- Proteinbestimmung (1)
- Proteinkinase (1)
- Proteins (1)
- Proteintyrosinphosphatasen (1)
- Proteinuria (1)
- Proteinurie (1)
- Protektion (1)
- Proteostasis (1)
- Protestantism (1)
- Protestbewegung (1)
- Prothese (1)
- Prothrombin complex concentrate (1)
- Prothrombinmutation (1)
- Protocol (1)
- Protokoll-Compliance (1)
- Proton density (1)
- Prototypes (1)
- Proximal (1)
- Proximal humeral fracture (1)
- Proximale Ballonokklusion (1)
- Prä-B-Zellen (1)
- Präanalytik (1)
- Prädiktor (1)
- Präkonditionierung (1)
- Präpulsinhibition (1)
- Präsenzdiagnostik (1)
- Präzision und Richtigkeit (1)
- Prüfung (1)
- Prüfungen (1)
- Prüfungserfolg (1)
- Prüfungsfragen (1)
- Pseudo HE-images (1)
- Pseudophakia (1)
- Pseudoprogression (1)
- Psoriasis vulgaris (1)
- Psoriatic arthritis (1)
- Psychiatric traits (1)
- Psychiatrie (1)
- Psychiatry (1)
- Psycho-oncology (1)
- Psychoanalyse (1)
- Psychodynamic psychotherapy (1)
- Psychological stress (1)
- Psychometric evaluation (1)
- Psychometrics (1)
- Psychometrie (1)
- Psychopathologie (1)
- Psychopathology (1)
- Psychophysics (1)
- Psychophysiologie (1)
- Psychosocial (1)
- Psychosomatik (1)
- Pteridine (1)
- Public and occupational health (1)
- Publication (1)
- Publication output (1)
- Pulmonale Hypertonie (1)
- Pulmonary artery pressure (1)
- Pulmonary disease, chronic obstructive (1)
- Pulmonary edema (1)
- Pulmonary failure (1)
- Pulmonary hypoplasia (1)
- Pulse contour analysis (1)
- Pulse pressure variation (1)
- Pulsed SILAC (1)
- Pulswellengeschwindigkeit (1)
- Pumpkin seeds (1)
- Punktion (1)
- Pupillometry (1)
- Purdue Pegboard (1)
- Pustulosis (1)
- Pyogenic (1)
- Pyogenic spondylodiscitis (1)
- Pyramidenbahn (1)
- Pyruvate (1)
- Pyruvate Kinase (1)
- Python (1)
- Pädagoge/in (1)
- Pädiatrische Brandverletzung (1)
- Q80K (1)
- QA/QC (1)
- QOL (1)
- Qb-Test (1)
- QbTest® (1)
- Qualifikation (1)
- Qualitative Analyse (1)
- Qualitative Research [MeSH] (1)
- Qualitative analysis (1)
- Qualitative research [MeSH] (1)
- Qualitative study (1)
- Quality control (1)
- Quality management (1)
- Quality of Health Care [MeSH] (1)
- Quality of Teaching and Learning (1)
- Quality of health care [MeSH] (1)
- Quality standards (1)
- Quality, performance, safety and outcomes (1)
- Qualität (1)
- Qualitätsindikator (1)
- Qualitätsindikatoren (1)
- Qualitätssicherung der Lehre (1)
- Qualitätsstandards (1)
- Quantitative (q)T2 mapping (1)
- Quantitative Analyse (1)
- Quantitative Antikörpermessung (1)
- Quantitative Imaging (1)
- Quantitative Ultraschall-Osteodensitometrie (1)
- Quantitative magnetic resonance imaging (1)
- Quantitative research (1)
- Quantitative sensory testing (1)
- Quantitative trait (1)
- Quantitative trait loci (1)
- Quantra (1)
- Quarantine (1)
- Quasi-longitudinal study (1)
- Queere Kapitalismuskritik (1)
- Querschnittsstudie (1)
- Questionnaire - Psychometrics - Diagnostics (1)
- Quinine (1)
- Quinolinate phosphoribosyltransferase (1)
- Quinolinic acid (1)
- Quinolones (1)
- R (1)
- R programming language (1)
- R software (1)
- R406 (1)
- RA-1000 (1)
- RAD001 (1)
- RAF (1)
- RARP (1)
- RAS pathway (1)
- RAS-ID-Gramneg (1)
- RBC (1)
- RBC-depletion (1)
- RBFOX1 (1)
- RBS-R (1)
- RCC (1)
- RD cells (1)
- REM sleep (1)
- REMS (1)
- RESLES (1)
- RET (1)
- RGAG1 (1)
- RH30 cells (1)
- RIP (1)
- RIP1 (1)
- RIPK1 (1)
- RIS (1)
- RNA Biology (1)
- RNA chaperone (1)
- RNA extraction (1)
- RNA polymerase (1)
- RNA polymerase inhibitors (1)
- RNA processing (1)
- RNA processing machinery (1)
- RNA sequencing (1)
- RNA stability (1)
- RNA turnover (1)
- RNA virus (1)
- RNA viruses (1)
- RNA, Virale/ Blut (1)
- RNA, long noncoding (1)
- RNA-Bindeprotein (1)
- RNA-Interferenz (1)
- RNA-binding protein (1)
- RNA-templated DNA repair (1)
- RNA/MicroRNA (1)
- RNAP II (1)
- RNActive (1)
- RNAi (1)
- RNAi and CRISPR screens (1)
- RNAseq analysis (1)
- RND (1)
- ROC analyses (1)
- ROC-Analysen (1)
- ROS generation (1)
- ROS/RNS (1)
- ROSA (1)
- ROTEM (1)
- RPE65 (1)
- RRMS (1)
- RT-PCR (1)
- RT-PCR-detection (1)
- RT-qPCR (1)
- RTS (1)
- RUFY (1)
- RULA (1)
- RUNX1/ETO (1)
- Rab proteins (1)
- Rabbit (1)
- Rac1 (1)
- Race (1)
- Radial artery (1)
- Radiation Oncology (1)
- Radiation Protection Act (1)
- Radiation Protection Ordinance (1)
- Radiation exposure (1)
- Radiation induced diarrhoea (1)
- Radiation necrosis (1)
- Radical cystectomy (1)
- Radical nephrectomy (1)
- Radiofrequency (1)
- Radiofrequency ablation (1)
- Radiofrequenzablation (1)
- Radioiodine therapy (1)
- Radioiodine uptake test (1)
- Radiojodtherapie (1)
- Radioligandentherapie (1)
- Radiologie, Universität Frankfurt (1)
- Radiologische Diagnostik (1)
- Radiology (1)
- Radiology and imaging (1)
- Radiosurgery (1)
- Radiothérapie (1)
- Radiyal arter (1)
- Radon action plan (1)
- Radonmaßnahmenplan (1)
- Radonvorsorgegebiete (1)
- Ragulator complex (1)
- Rahmenbedingungen der Lehre (1)
- Raketenimmunelektrophorese (1)
- Ramadan (1)
- Raman spectroscopy (1)
- Ramucirumab (1)
- Ramón y Cajal (1)
- Randomisation (1)
- Randomised controlled trial (1)
- Randomised trial (1)
- Randomized (1)
- Randomized Controlled Trial (1)
- Randomized trial (1)
- RapL (1)
- Rapamycin (1)
- Rapid diagnostic test (1)
- Rapid eye movement sleep behavior disorder (1)
- Rare Diseases (1)
- Rare Diseases/ Orphan Diseases (1)
- Rare disease (1)
- Raster (1)
- Ratewahrscheinlichkeit (1)
- Rational use (1)
- Ratte (1)
- Rcf1 (1)
- Re-exploration (1)
- Re-exposure (1)
- Re-injury (1)
- Reactogenicity (1)
- Reading Disorder (1)
- Readmission (1)
- Ready-made mouthguard (1)
- ReagentKits, -Diagnostic (1)
- Reagenzkits, Diagnostische (1)
- Reaktionszeit (1)
- Real world study (1)
- Real-time MRI (1)
- Real-time phase contrast (1)
- Real-time polymerase chain reaction (PCR) tests (1)
- Real-world data (1)
- Real-world evidence (1)
- RealTime (1)
- Rearing temperature (1)
- Recall rate (1)
- Receptor physiology (1)
- Receptors/Nuclear (1)
- Rechtliche Würdigung (1)
- Rechtsmediziner (1)
- Recognition (1)
- Reconstructed human epidermis (1)
- Reconstruction (1)
- Reconstructive surgical procedures (1)
- Recurrence rate (1)
- Recurrent episodes (1)
- Red blood cells (1)
- Red yeast rice (1)
- Redox (1)
- Redox dependent epigenetic modifications (1)
- Redox modification (1)
- Redox-sensitive GFP (1)
- Redox-sensitive transcription factor (1)
- Redoxregulation (1)
- Reduktion von Komplikationen (1)
- Redundancy (1)
- Reference (1)
- Reference values (1)
- Referenzwerte (1)
- Referral (1)
- Reflotron® (1)
- Refractive changes (1)
- Refractive lense exchange (1)
- Refractory AML (1)
- Refractory status epilepticus (1)
- Refraktärer Status epilepticus (1)
- RegJoint™ (1)
- Regenerative medicine (1)
- Region (1)
- Region of Interest (1)
- Regret (1)
- Regulatory T cells (1)
- Regulatory agencies. (1)
- Regulatory framework (1)
- Regulatory networks (1)
- Rehospitalization (1)
- Reintervention (1)
- Reiseapotheke (1)
- Reisedurchfall (1)
- Reisefieber (1)
- Reiseimpfungen (1)
- Reisemedizinische Beratung (1)
- Rekonstruktion (1)
- Rekonstruktive chirurgische Verfahren (1)
- Relapse (1)
- Relapse surveillance (1)
- Relapsed ALL (1)
- Relative quantification (1)
- Relaxometrie (1)
- Release of mtDNA and mtRNA (1)
- Reliability (1)
- Remission (1)
- Remote ischemic conditioning (1)
- Remote monitoring (1)
- Renal cancer (1)
- Renal function (1)
- Renal lesions (1)
- Renal replacement therapy (1)
- Renin-Angiotensin-Aldosteron-System (1)
- Repatriation of corpses (1)
- Reperfusion (1)
- Repetitives Verhalten (1)
- Replication study (1)
- Replikon (1)
- Repositioning drugs (1)
- Representative survey (1)
- Reproducibility/stability (1)
- Reproduktionsmedizin (1)
- Requirements engineering (1)
- Research (1)
- Research data (1)
- Research design (1)
- Research investment (1)
- Research patterns (1)
- Research trends (1)
- Research validity (1)
- Resection (1)
- Reservoir function (1)
- Residency (1)
- Residential care (1)
- Residential facilities (1)
- Residual myometrial thickness (1)
- Resilience (1)
- Resin composites (1)
- Resistenzentwicklung (1)
- Resistenzprüfung (1)
- Resistenztestung (1)
- Resource competition (1)
- Respimat® Soft Mist™ Inhaler (1)
- Respiratorische Infekte (1)
- Respiratory Syncytial Virus (1)
- Respiratory signs and symptoms (1)
- Respiratory syncytial virus (1)
- Respiratory tract diseases (1)
- Response (1)
- Response control (1)
- Response criteria (1)
- Responsibility of healthcare policy (1)
- Ressourcen (1)
- Resting state (1)
- Restricted posture (1)
- Restriktionsanalyse (1)
- Restriktive und Repetitive Verhaltensweisen (1)
- Resuscitation (1)
- Reticulon (1)
- Retikulozytenbestimmung (1)
- Retinal degeneration (1)
- Retinal diseases (1)
- Retinoic acid (1)
- Retro-IDEAL (1)
- Retrospective studies (1)
- Retrospective study (1)
- Rettungsdienst (1)
- Return to play (1)
- Return to sports (1)
- Return to work (1)
- Reverse electron transfer (1)
- Reverse transcription polymerase chain reaction (1)
- Review (1)
- Revision (1)
- Revisionsprothese (1)
- Reward anticipation (1)
- Reward system (1)
- Rezeptorsignalweg (1)
- Rezidivprophylaxe (1)
- Rezidivrate (1)
- Rh Antigens (1)
- Rhabarber (1)
- Rhabarber <Gattung> (1)
- Rhabdomyoma (1)
- Rhabdomyosarkom (1)
- Rheuma (1)
- Rheumatology (1)
- Rhinosinusitis (1)
- Rho GTPases (1)
- Rho-kinase (1)
- Rho/Rho-kinase (1)
- RhoA (1)
- RhoGTPases (1)
- Rhythmologie (1)
- Ribosomal RNA (1)
- Ribosomal S6 phosphorylation (1)
- Ribosomal translation (1)
- Ribosomes (1)
- Richtigkeit (1)
- Richtlinien (1)
- Ridge preservation (1)
- Riftia pachyptila (1)
- Right hemisphere (1)
- Ringversuch (1)
- Risikogruppen sind: Schwangerschaft - Bluttransfusion - Organtransplantation - Prostituierte (1)
- Risikokommunikation (1)
- Risikomanagement (1)
- Risk communication (1)
- Risk prediction (1)
- Risk reduction (1)
- Risk-stratification (1)
- Roboter (1)
- Robotic Radiosurgery (1)
- Robotic tracking (1)
- Robotic-assisted radical prostatectomy (1)
- Robotik (1)
- Rocket immunoelectrophoresis (1)
- Rodents (1)
- Roe deer (1)
- Rolandic Spikes (1)
- Roma women (1)
- Rora (1)
- Rotorest (1)
- Roughness (1)
- Round window membrane (1)
- Roussel Uclaf Causality Assess- ment Method (RUCAM) (1)
- Routinedaten (1)
- Routinely Collected Health Data [MeSH] (1)
- Roux-en-Y gastric bypass (1)
- Rtn3 (1)
- Ruijs-Aalfs syndrome (1)
- Running Economy (1)
- Rural areas (1)
- Rush (1)
- Rush protocol (1)
- Rush-SIT (1)
- Russell-Taylor-Nagel (1)
- Russell-Taylor-Nail (1)
- Ruxolitinib (1)
- Ryanodine (1)
- Récidive (1)
- Réserve ovarienne (1)
- Röntgendiagnostik (1)
- Röntgendiffraktion (1)
- Rückenschmerzen (1)
- S. cerevisiae (1)
- S100 calcium‑binding protein B (1)
- S100A12 Hexamer (1)
- S100b (1)
- S1P1 receptor (1)
- S1P1–5 (1)
- S1P5 (1)
- S1PR1 (1)
- S1PR4 (1)
- S1PR5 (1)
- S63845 (1)
- SAGE (1)
- SAH (1)
- SAH close (1)
- SAMHD1 knockout mouse (1)
- SAMHD1 phosphorylation (1)
- SAP (1)
- SARS CoV 2 (1)
- SARS-CoV (1)
- SARS-CoV-2-specific T cells (1)
- SARS-CoV2 (1)
- SARS-CoV‑2 pandemic (1)
- SARS-CoV‑2-Pandemie (1)
- SAVI (1)
- SCA2 (1)
- SCA34 (1)
- SCA38 (1)
- SCD14 (1)
- SCMR (1)
- SCN5A (1)
- SCT (1)
- SDF-1 (1)
- SDH (1)
- SDS (1)
- SEAP (1)
- SEC (1)
- SEC-ICP-DRC-MS (1)
- SEER (1)
- SELEX (1)
- SENP6 (1)
- SEREX (1)
- SERS (1)
- SF-12 (1)
- SF-12 WOMAC KSS (1)
- SFR (1)
- SGPL1 (1)
- SGPL1 knockout cell line (1)
- SH- (S-S)-Groups (1)
- SH-SY5Y (1)
- SH-SY5Y neuroblastoma cells (1)
- SHH (1)
- SIADH (1)
- SIDS (1)
- SILAC (1)
- SIRPalpha (1)
- SKALE score (1)
- SKI II (1)
- SLAM-seq (1)
- SLC20A1 (1)
- SLC6a3 (1)
- SLC7A11 (1)
- SLP-76 (1)
- SLUG (1)
- SMAD (1)
- SMAD signaling (1)
- SMOC1 (1)
- SNORD95 (1)
- SNV (1)
- SOCS (1)
- SOFA (1)
- SPARTAN (1)
- SPG8 (1)
- SPPL3 (1)
- SPRTN (1)
- SPSS (1)
- SR protein (1)
- SR-BI (1)
- SRSF3 (1)
- SRSF7 (1)
- SSRI (1)
- SSTI (1)
- ST2L (1)
- STAMPE2 (1)
- STAT5 (1)
- STDP (1)
- STI 571 (1)
- STIR (1)
- SUD (1)
- SUMO chains (1)
- SUMO1-3 (1)
- SUMOylation (1)
- SUN1 (1)
- SUN2 (1)
- SUV (1)
- SW480 Cell (1)
- SW480 cells (1)
- SWATH (1)
- Saccades (1)
- Saccadometry (1)
- Safety culture (1)
- Safety equipment (1)
- Safety learning (1)
- Safety perspectives (1)
- Salivary gland cancer (1)
- Salivary gland carcinoma (1)
- Salivary gland diseases (1)
- Salmonella choleraesuis (1)
- Salmonella infection (1)
- Salt inducible kinase 2 (SIK2) (1)
- Salvage therapy (1)
- Sampling protocol (1)
- Sandfly (1)
- Sanger Sequencing (1)
- Sapacitabine (1)
- Sarcomas (1)
- Sarcopenia (1)
- Sarcophagidae (1)
- Sarkoidose (1)
- Satisfaction (1)
- Saudi Arabia (1)
- Sauerstoffpartialdruck (1)
- Sauerstoffpuls (1)
- Saure Dissoziation (1)
- Scaffold (1)
- Scalp defect (1)
- Scanner models (1)
- Scedosporium spp. (1)
- Schaftposition (1)
- Scheduling of radiotherapy (1)
- Schilddrüse (1)
- Schilddrüsenhormone (1)
- Schlafentzug (1)
- Schlaganfall-Sekundärprophylaxe (1)
- Schlagvolumen (1)
- Schmerzforschung (1)
- Schmerzprävalenz (1)
- Schmerztherapie (1)
- School support (1)
- Schulter (1)
- Schwangerschaftstumor (1)
- Schädel-MRT (1)
- Science structure (1)
- Scientifi c competence (1)
- Scientific community (1)
- Scientific publishing (1)
- Scientometria (1)
- Scientometric analysis (1)
- Scientometrics (1)
- Scientometry (1)
- Sclerostin (1)
- Sclerotic glomeruli (1)
- Screening guidelines (1)
- Screening-ELISA (1)
- Screeningfragebogen (1)
- Scrofulous keratitis (1)
- Seasonal variation (1)
- Seattle heart failure model (1)
- Second donation (1)
- Second stage of labor (1)
- Second-line treatment (1)
- Secondary injury cascades (1)
- Secondary prevention (1)
- Secondhand Smoke (1)
- Secretion (1)
- Sectio (1)
- Secular trend (1)
- Sedation (1)
- Sedatives (1)
- Sedierung (1)
- Seizure series (1)
- Sektion (1)
- Sektionsart (1)
- Sekundärversagen (1)
- Selbstbeteiligung (1)
- Selbstmord (1)
- Selbstmordpakt (1)
- Selbstverwaltung (1)
- Selbstvorstellung (1)
- Selection bias (1)
- Selective autophagy (1)
- Selen (1)
- Selenium (1)
- Selenium administration in gynecologic radiation oncology (1)
- Selenoproteins (1)
- Self-assessment (1)
- Self-efficacy (1)
- Self-esteem (1)
- Self-expandable TAVI (1)
- Self-expandable metal stent (SEMS) (1)
- Self-expandable metal stents (1)
- Self-expandable metal stents complications (1)
- Self-introduction (1)
- Self-management support (1)
- Self-myofascial release (1)
- Self-report (1)
- Seltene Erkrankungen in der Lehre (1)
- Semicontinuous (1)
- Seminom (1)
- Semitendinosus tendon autograft (1)
- Sensorimotor processing (1)
- Sensorimotor training (1)
- Sensory Neuroscience (1)
- Sensory neuron (1)
- Sensory perception (1)
- Sensory systems (1)
- Separation of ADP-Binding Enzymes (1)
- Sepsis-bundle (1)
- Septic shock (1)
- Septischer Schock (1)
- Sequelae (1)
- Sequence (1)
- Sequence alignment (1)
- Sequence motif analysis (1)
- Sequencing (1)
- Sequential (1)
- Sequenzanalyse <Chemie> (1)
- Seralyzer-System (1)
- Seralyzer® (1)
- Seribantumab (1)
- Serine proteases (1)
- Serious injured children (1)
- Seroconverter (1)
- Serodiagnostik (1)
- Seroepidemiology (1)
- Serology (1)
- Serotonin (1)
- Serotype 3 (1)
- Serum Susceptibility (1)
- Serum biomarker (1)
- Severe Acute Respiratory Syndrome (1)
- Severe bacterial infection (1)
- Severe blood loss (1)
- Severe malaria (1)
- Severity of illness index (1)
- Sexual Dysfunctions (1)
- Sexual child abuse (1)
- Sexual violence (1)
- Sexualmedizin (1)
- Sexuelle Dysfunktionen (1)
- Sexuelle Gewalt (1)
- Sexuelle Revolution (1)
- Sexueller Kindesmissbrauch (1)
- Shannon index (1)
- Shared information (1)
- Sharp injuries (1)
- Sharpin (1)
- Sholl analysis (1)
- Shone’s complex (1)
- Shortage of recruits (1)
- Shoulder joint (1)
- Shoulder luxation (1)
- Shunt-Operation (1)
- Sialic acid (1)
- Sialinsäure (1)
- Sickle Cell Disease (1)
- Side effect (1)
- Side effects (1)
- Siderosis (1)
- Signal Recognition Particle (1)
- Signal Transduction (1)
- Signal intensity (1)
- Signal transduction (1)
- Signaling ROS (1)
- Signaling pathway (1)
- Signs and symptoms (1)
- Silicosis (1)
- Silver diamine fluoride (1)
- Silver in situ hybridization (1)
- Simulation and modeling (1)
- Simulation komplexer Systeme (1)
- Simulator (1)
- Simultaneous (1)
- Single nucleotide polymorphism (1)
- Single positive core biopsy (1)
- Single-Molecule Localization Microscopy (SMLM) (1)
- Single-cell RNA sequencing (1)
- Single-cell RNA-seq (1)
- Single-cell RNA-sequencing (1)
- Single-leg hop for distance (1)
- Single-treatment (1)
- Sinus pilonidalis (1)
- Sirolimus (1)
- Sistemas de Saúde (1)
- Sitafloxacin (1)
- Sitting posture (1)
- Sitzhaltung (1)
- Skeletal health (1)
- Skeletal joints (1)
- Skeletal muscle (1)
- Skeletal muscle fiber-type switching (1)
- Skeletal muscles (1)
- Skills training (1)
- Skin fibroblast (1)
- Skin irritation test (1)
- Skin manifestation (1)
- Skin morphology (1)
- Skp (1)
- Skull base (1)
- Slc11a2 (1)
- Slc25a37 (1)
- Sleep deprivation (1)
- Slow Cortical Potentials, SCP (1)
- Smac mimetic (1)
- Smac mimetics (1)
- Smad (1)
- Small Cell/diagnosis (1)
- Small Leucine-rich Proteoglycan (SLRP) (1)
- Small RNA analysis (1)
- Small bowel atresia (1)
- Small bowel endoscopy (1)
- Small molecules (1)
- Small vessel disease (1)
- Small- and medium-sized enterprises (1)
- Small-bowel endoscopy (1)
- Small-cell lung cancer (1)
- Smart nebulizer (1)
- Smooth muscle (1)
- Smooth muscle cell (1)
- Smooth muscle cells (1)
- Snakebite (1)
- Social Phobia (1)
- Social brain (1)
- Social cognition (1)
- Social communication (1)
- Social decision-making (1)
- Social determinants (1)
- Social differences (1)
- Social information processing (1)
- Social neuroscience (1)
- Social phobia (1)
- Social research (1)
- Social sciences (1)
- Social skills training (1)
- Social support (1)
- Sociocognitive predictors (1)
- Sociodemographic characteristics (1)
- Socioeconomic analysis (1)
- Socioeconomic indices (1)
- Socket healing (1)
- Socket preservation (1)
- Sodium chloride (1)
- Soecificity (1)
- Sofortbelastung (1)
- Soft skills (1)
- Soft tissue healing (1)
- Soft tissue infection (1)
- Soft tissue sarcoma (1)
- Soft-tissue sarcoma (1)
- Software (1)
- Software tool (1)
- Software tools (1)
- Softwareentwicklung (1)
- Solanaceae (1)
- Solar insolation (1)
- Solidarität (1)
- Solidworks 2015 (1)
- SoloSTAR (1)
- Soluble epoxide hydrolase (1)
- Somatization (1)
- Sonographie (1)
- Sonography (1)
- Sotalol (1)
- Source reconstruction (1)
- Sozialpolitik (1)
- Sozialpsychiatrischer Dienst (1)
- Sozialstaat (1)
- Sozialstaatsprinzip (1)
- Spa water (1)
- Spanish National Health System (1)
- Sparse models (1)
- Spatial Attention (1)
- Specialist training (1)
- Specialized outpatient palliative care (1)
- Species identification (1)
- Speciesidentification (1)
- Specific Synthesis (1)
- Specimen preparation and treatment (1)
- Spectral library (1)
- Spectraldomain OCTA (1)
- Spectrin (1)
- Speech signal processing (1)
- Speicherung (1)
- Spezialisierte ambulante Palliativversorgung (1)
- Speziesbarriere (1)
- Sphere Formation Assay (1)
- Sphingolipid (1)
- Sphingolipidstoffwechsel (1)
- Sphingosine 1-phosphate (1)
- Sphingosine-1-phosphate (1)
- Sphk1 (1)
- Sphk2 (1)
- Spinal fractures (1)
- Spinal injuries (1)
- Spinal surgery (1)
- Spinalanästhesie (1)
- Spinalkanalstenose (1)
- Spine Register (1)
- Spine care (1)
- Spine density (1)
- Spine fractures (1)
- Spine infection (1)
- Spinocerebellar ataxia (1)
- Spinocerebellar ataxia type 2 (1)
- Spirochetes (1)
- Splanchnic Hemodynamics (1)
- Spleen (1)
- Splenic dendritic cell (1)
- Splice variants (1)
- Spondylitis (1)
- Spondyloarthritis (1)
- Spondylodiscitis (1)
- Spondylolisthesis (1)
- Spontan bakterielle Peritonitis (1)
- Spontaneous bacterial peritonitis (1)
- Sportler (1)
- Sportliche Leistungsfähigkeit (1)
- Sports (1)
- Spot sign (1)
- Spread of Excitation (1)
- Spurenelemente (1)
- Sputum smear-negative (1)
- StUbL (1)
- Staatsexamen (1)
- Stability (1)
- Staff load (1)
- Stage at presentation (1)
- Stakeholder participation (1)
- Stammzelle (1)
- Stammzellen (1)
- Stammzelltherapie (1)
- Standard dataset (1)
- Standard reference values (1)
- Standard risk (1)
- Standardized operating procedures (1)
- Standards of care (1)
- Standardverfahren (1)
- Staphylococcus aureus (1)
- Stark verwester Leichnam (1)
- Staroperation (1)
- Starvation (1)
- Static MRI (1)
- Statin (1)
- Stationäre Krankenhausfälle (1)
- Statistical methods (1)
- Status quo Seltene Erkrankungen (1)
- Stavudine (1)
- Steatosis (1)
- Steinfreiheit (1)
- Stem cell dose (1)
- Stem cell enumeration (1)
- Stenosis (1)
- Stenotrophomonas maltophilia (1)
- Stentimplantation (1)
- Stentoplasty (1)
- Stereoelektroenzephalographie (1)
- Stereoisomerie (1)
- Stereoisomers (1)
- Stereotactic ablative body radiotherapy (1)
- Stereotactic radiosurgery (1)
- Sterilität (1)
- Sternberg-Aufgabe (1)
- Steroid (1)
- Sterols (1)
- Stigma (1)
- Stigma scale (1)
- Stilbene (1)
- Stimulant (1)
- Stimulation experiments (1)
- Stimulus-secretion coupling (1)
- Sting challenge (1)
- Stoma (1)
- Stoppa approach (1)
- Strahlendosis (1)
- Strahlenschutzgesetz (1)
- Strahlenschutzverordnung (1)
- Straßburg, Reichsuniversität (1)
- Streptokokken (1)
- Streptomyces hydrogenans (1)
- Stress (1)
- Stress and resilience (1)
- Stress resilience (1)
- Stress vulnerability/resilience genes (1)
- Stretch training (1)
- Streustrahlung (1)
- Stringed bow player (1)
- Stroke Risk (1)
- Stroke genetics (1)
- Stroke prevention (1)
- Stroke volume variation (1)
- Stromal cell (1)
- Structural MRI (1)
- Structural genomics (1)
- Structured reporting (1)
- Structured written feedback (1)
- Strukturwandel der Sexualität (1)
- Student (1)
- Studentenproteste Frankfurt am Main (1)
- Students (1)
- Studiendauer (1)
- Studium mit Kind (1)
- Störfaktoren (1)
- Störfaktoren in der serologischen Diagnostik (1)
- Sub-segmentation (1)
- Sub-zero exposure (1)
- Subacute cerebellar degeneration (1)
- Subarachnoid Hemorrhage (1)
- Subcortical (1)
- Subcutaneous (1)
- Subdural Haematoma (1)
- Subdurales Hämatom (1)
- Subependymal giant cell astrocytoma (1)
- Subgroup identification (1)
- Subjective effects (1)
- Subjective health status (1)
- Subjekt (1)
- Subjektiver Gesundheitszustand (1)
- Subkortikal (1)
- Subpopulation (1)
- Substances for disinfection (1)
- Substitution of Ribose (1)
- Subterranean (1)
- Subventricular zone (1)
- Sudden Cardiac Death (SCD) (1)
- Sudden infant death syndrome (1)
- Sugar feeding (1)
- Suicidal behavior (1)
- Suicidal ideation (1)
- Suicidal thoughts (1)
- Suicide attempt (1)
- Suizid (1)
- Sulfasalazine (1)
- Sulfhydryl Groups (1)
- Sulfhydryl-reactivity (1)
- Sulforaphane (1)
- Sulfur metabolism (1)
- Sulphoraphane (1)
- Sunlight (1)
- Superimposition (1)
- Superinfection (1)
- Supplemental parenteral nutrition (1)
- Support vector machine (1)
- Supported Decision-making (1)
- Supraglottic Airway Devices (1)
- Supraspinatus tendon (1)
- Supratentorial (1)
- Supraventricular arrhythmias (1)
- Supreme court ruling (1)
- Surface (1)
- Surfactantlavage (1)
- Surgical APGAR Score (1)
- Surgical ICU (1)
- Surgical blood loss (1)
- Surgical education (1)
- Surgical risk (1)
- Surgical site infection (1)
- Surgical site occurrence (1)
- Surgical therapy (1)
- Surrogate endpoint (1)
- Survey (1)
- Surveys (1)
- Survival data (1)
- Suspension (1)
- Sustainable Development (1)
- Sustained attention (1)
- Sustained virologic response (1)
- Sustained virological response (1)
- Sustained virological response (SVR) (1)
- Swallowing (1)
- Sweat osmolality (1)
- Sweat secretion rate (1)
- Swept-source OCTA (1)
- Switzerland (1)
- Sycamore (1)
- Syk Kinase (1)
- Syllables (1)
- Symmetrical blocked occlusion (1)
- Sympathetic (1)
- Sympathicolysis (1)
- Symptome (1)
- Symptoms (1)
- Synapse (1)
- Synapses (1)
- Synaptic dysfunction (1)
- Synaptic organizer (1)
- Synaptopodin (1)
- Synaptosomal preparation (1)
- Syncope (1)
- Syndecan-1 (1)
- Syndrome des ovaires polykystiques (1)
- Synergy (1)
- Synovial inflammation (1)
- Synthetic (1)
- Synthetic biology (1)
- Synthetische Gestagene (1)
- Synthetische Letalität (1)
- Syrian hamster (1)
- Systemic inflammatory response (1)
- Systemic lupus erythematosus (1)
- Systemic treatment (1)
- Systemischer Erythematodes (1)
- Systems & Computational Biology (1)
- Systems biology (1)
- Systems medicine (1)
- Szientometrie (1)
- Säkularer Trend (1)
- Sérotonine (1)
- T Cell Biology (1)
- T Cells (1)
- T cell receptor (1)
- T cell receptors (1)
- T cell/histiocyte rich large B cell lymphoma (1)
- T helper 17 cells (1)
- T helper cell differentiation (1)
- T-ALL (1)
- T-DM1 (1)
- T-Zell-Depletion (1)
- T-Zellen (1)
- T-bet (1)
- T-cell development (1)
- T-cell homeostasis (1)
- T-cell homing (1)
- T-cell niche (1)
- T-cell receptor (TCR) (1)
- T-cell targeting (1)
- T-cell-depletion (1)
- T-lymphocytes (1)
- T-tubule system (1)
- T-wave alternans (1)
- T1 (1)
- T1 and T2 mapping (1)
- T1 mapping (1)
- T2 (1)
- T4-Bestimmung (1)
- T4-analysis (1)
- T84 colon carcinoma cells (1)
- TALE-homdomain protein (1)
- TAM (1)
- TAMs (1)
- TAPSE (1)
- TAVI Vergleich transapikaler transfemoraler Zugangsweg (1)
- TAVI, Kardiologie, Klappen, Aortenklappenstenose, Prothesen, TTE, Frankfurt, Vergleich, Transkatheter, Mortalität, Herz (1)
- TAVR (1)
- TAX1BP1 (1)
- TB-therapy (1)
- TBI (1)
- TC stenosis (1)
- TCR signaling cascade (1)
- TDAG8 (1)
- TDM (1)
- TEER (1)
- TEM (1)
- TEOAE (1)
- TEPT (1)
- TEVAR (1)
- TG-186 (1)
- TG-43 (1)
- TGF-beta (1)
- TGF-α (1)
- TGFB-induced factor homeobox 1 (1)
- TGIF (1)
- TGR(mREN2)27 (1)
- THRLBCL (1)
- THV (1)
- TIA-1 (1)
- TIC10 (1)
- TIGAR (1)
- TILs (1)
- TIM23 (1)
- TIMP2 (1)
- TIRADS (1)
- TL AOSIS (1)
- TLR (1)
- TLR2 (1)
- TLR2/6 (1)
- TLR4 (1)
- TLR7 (1)
- TLR8 (1)
- TMC435 (1)
- TME (1)
- TMEM126B (1)
- TMS (1)
- TMS-EEG (1)
- TNF (1)
- TNF inhibitors (1)
- TNF-α (1)
- TNFR1 (1)
- TOR inhibitor (1)
- TOR signalling (1)
- TOR1A (1)
- TP53 (1)
- TP53 mutation status (1)
- TP53-induced glycolysis and apoptosis regulator (1)
- TPR (1)
- TRAPP (1)
- TRIM25 (1)
- TRIMs (1)
- TRP Channels (1)
- TRP2 (1)
- TRPM8 (1)
- TRPV4 (1)
- TSC-associated neuropsychiatric disorders (1)
- TSC22D3 (1)
- TSH (1)
- TSP-4 (1)
- TTFields (1)
- TTW nodules (1)
- TUR-P (1)
- TURP (1)
- TVT (1)
- TWINKLE (1)
- TWNK (1)
- Tabak (1)
- Tabakkonsum (1)
- Taekwondoka (1)
- Tagging (1)
- Tailored medicine (1)
- Takotsubo Syndrome (1)
- Tamoxifen (1)
- Tamponade (1)
- Tanz (1)
- Tar (1)
- Targeted delivery (1)
- Targeted sequencing (1)
- Targeted tumor therapy (1)
- Tas2r126 (1)
- Tas2r135 (1)
- Tas2r143 (1)
- Tau (1)
- Tau acetylation (1)
- Tax effect (1)
- Taxane (1)
- Taxonomy (1)
- Tea (1)
- Teaching and Learning conditions (1)
- Teaching in daily surgical routine (1)
- Technical data (1)
- Technicians (1)
- Technique (1)
- Teilzeit (1)
- Tele-consultation (1)
- Telekonsil (1)
- Telomerase (1)
- Telomere length (1)
- Telomeres (1)
- Tempo-parietal junction (1)
- Temporal lobe epilepsy (1)
- Temporomandibular joint (1)
- Temporomandibular joint dysfunction (1)
- Temsirolimus (1)
- Tendon incontinence repair (1)
- Tendon transplantation (1)
- Term birth (1)
- Terminal ileitis (1)
- Terminology (1)
- Test assay (1)
- Testing (1)
- Testosterone (1)
- Teststreifenanalytik (1)
- Tet-inducible system (1)
- Tetanus (1)
- Tetrahydro-Aldosteron (1)
- Texture analysis (1)
- Tfrc (1)
- Tgfβ (1)
- Th1 polarization (1)
- Thalidomide (1)
- Theorie der Sexualität (1)
- Theranostik (1)
- Therapeutic adherence (1)
- Therapeutic anticoagulation (1)
- Therapeutic competence (1)
- Therapeutics (1)
- Therapiefreie Remission (1)
- Therapielimitierung (1)
- Therapiemonitoring (1)
- Therapies (1)
- Therapy response (1)
- Thermal injury (1)
- Thermal spring water (1)
- Thermische Verletzung (1)
- Thermoablation (1)
- Thermodilution (1)
- Thermogenesis (1)
- Thermometrie (1)
- Thermometry (1)
- Thermoplasma (1)
- Thermoplasma acidophilum Membranes; Tetraetherlipids (1)
- Thiol redox modification (1)
- Thioredoxin-1 (1)
- Thorax (1)
- Thoraxbiopsie (1)
- Three-dimensional back scan (1)
- Three-dimensional echocardiography (1)
- Threonin (1)
- Thrombin (1)
- Thromboembolische Ereignisse (1)
- Thrombosis/hypercoagulable states (1)
- Thrombotic microangiopathy (1)
- Thromboxane (1)
- Thrombozytenaggregation (1)
- Thrombozytenaktivierung (1)
- Thrombozytentransfusion (1)
- Thumb carpometacarpal joint osteoarthritis (1)
- Thymocytes (1)
- Thymus (1)
- Thyreoiditis (1)
- Thyreostatika (1)
- Thyroid Cancer Cells (1)
- Thyroid disease (1)
- Thyréostatiques (1)
- Tick (1)
- Tick-Borae (1)
- Tick-Born Diseases (1)
- Tick-Borne diseases (1)
- Tick-borne encephalitis (1)
- Ticks (1)
- Tiermodell (1)
- Time in therapeutic range (TTR) (1)
- Time of death (1)
- Time optimization (1)
- Time series (1)
- Time to treatment failure (1)
- Time trend (1)
- Timing (1)
- Tinnitus (1)
- Tissue Engineering (1)
- Tissue expander (1)
- Tissue microarray (1)
- Tissue microarray (TMA) (1)
- Tissue stiffness (1)
- Tissue-specificity (1)
- Tobacco (1)
- Tocilizumab (1)
- Todesumstand (1)
- Todesursache (1)
- Toll-like Receptor (TLR) (1)
- Toll-like Rezeptor, Subcommissuralorgan; Circumventriculäre Organe (1)
- Toll-like receptor (TLR) 6 (1)
- Toll-like receptors (1)
- Toll-like-Rezeptoren (1)
- Toluidine blue (1)
- Tonsil (1)
- Tonsillitis (1)
- Tools and ressources (1)
- Tooth Development (1)
- Tooth segmentation (1)
- Tooth transplantation (1)
- Topoisomerase (1)
- Total Quality Managemen (1)
- Total colonoscopy (1)
- Total elbow arthroplasty (1)
- Total hip arthroplasty (1)
- Total hip replacement (1)
- Total operating room time (1)
- Touchscreen (1)
- Touristikmedizin (1)
- Toxic liver disease (1)
- Toxicité ovarienne (1)
- Toxicology (1)
- Toxikologie (1)
- Toxins (1)
- Tozasertib (1)
- Tracheal Intubation (1)
- Tracktographie (1)
- Traditional Chinese Medicine (TCM) (1)
- Traditional Indian Medicine (1)
- Trafficking (1)
- Tragen (1)
- Trail (1)
- Traits of medical students (1)
- Trajectories (1)
- Tranexamic acid (1)
- Tranexamsäure (1)
- Transbrachial Angiography (1)
- Transbrachiale Angiographie (1)
- Transcatheter Aortic Valve Implantation (1)
- Transcatheter based aortic valve implantation (1)
- Transcatheter stage 1 (1)
- Transcranial direct current stimulation (1)
- Transcription factor (1)
- Transcription regulation (1)
- Transcriptional control (1)
- Transcriptional regulatory elements (1)
- Transcriptome (1)
- Transcriptome analysis (1)
- Transcriptome microarray (1)
- Transcriptomics (1)
- Transdifferentiation (1)
- Transduction (1)
- Transesophageal echocardiography (1)
- Transfer learning (1)
- Transfer model (1)
- Transferases (1)
- Transformation (1)
- Transfusion practice (1)
- Transfusionsbedingte virale Infektionen (1)
- Transfusionszwischenfall (1)
- Transgenic SK-2 mice (1)
- Transgenic mice (1)
- Transidente Kinder und Jugendliche (1)
- Transient (1)
- Transient elastography (1)
- Transient ischemic attack (1)
- Transiente Elastographie (1)
- Transition invariant (1)
- Transitional cell carcinoma (1)
- Transitional fractures 3D printing (1)
- Transjugular Intrahepatic Portosystemic Shunt (1)
- Transjugular intrahepatic portosystemic shunt (1)
- Translation (1)
- Translation initiation (1)
- Translation proteomics (1)
- Translational (1)
- Translationsregulation (1)
- Transmembrane communication (1)
- Transplant logistics (1)
- Transplantation Centers (1)
- Transplantation/Immunologie (1)
- Transplantation/immunology (1)
- Transplantatnephrektomie (1)
- Transplantatvaskulopathie (1)
- Transportation (1)
- Transurethral resection of the prostate (1)
- Trastuzumab (1)
- Trauma centre (1)
- Trauma surgery (1)
- TraumaRegister DGU® (1)
- TraumaRegister DGU® (TR-DGU) (1)
- Traumatic dental injury (1)
- Traumatologie (1)
- Traumatology (1)
- Travel Health Advisory (1)
- Travel immunisations (1)
- Travel medicine (1)
- Travel regulations (1)
- Travel times (1)
- Travellers (1)
- Treatment costs (1)
- Treatment effectiveness (1)
- Treatment management (1)
- Treatment modification (1)
- Treatment protocol (1)
- Treatment rates (1)
Institute
- Medizin (7659) (remove)
We conducted a systematic review investigating the efficacy and tolerability of adrenocorticotropic hormone (ACTH) and corticosteroids in children with epilepsies other than infantile epileptic spasm syndrome (IESS) that are resistant to anti-seizure medication (ASM). We included retrospective and prospective studies reporting on more than five patients and with clear case definitions and descriptions of treatment and outcome measures. We searched multiple databases and registries, and we assessed the risk of bias in the selected studies using a questionnaire based on published templates. Results were summarized with meta-analyses that pooled logit-transformed proportions or rates. Subgroup analyses and univariable and multivariable meta-regressions were performed to examine the influence of covariates. We included 38 studies (2 controlled and 5 uncontrolled prospective; 31 retrospective) involving 1152 patients. Meta-analysis of aggregate data for the primary outcomes of seizure response and reduction of electroencephalography (EEG) spikes at the end of treatment yielded pooled proportions (PPs) of 0.60 (95% confidence interval [CI] 0.52–0.67) and 0.56 (95% CI 0.43–0.68). The relapse rate was high (PP 0.33, 95% CI 0.27–0.40). Group analyses and meta-regression showed a small benefit of ACTH and no difference between all other corticosteroids, a slightly better effect in electric status epilepticus in slow sleep (ESES) and a weaker effect in patients with cognitive impairment and “symptomatic” etiology. Obesity and Cushing's syndrome were the most common adverse effects, occurring more frequently in trials addressing continuous ACTH (PP 0.73, 95% CI 0.48–0.89) or corticosteroids (PP 0.72, 95% CI 0.54–0.85) than intermittent intravenous or oral corticosteroid administration (PP 0.05, 95% CI 0.02–0.10). The validity of these results is limited by the high risk of bias in most included studies and large heterogeneity among study results. This report was registered under International Prospective Register of Systematic Reviews (PROSPERO) number CRD42022313846. We received no financial support.
Key points
* Systematic review resulting in low to moderately solid evidence on the efficacy and tolerability of adrenocorticotropic hormone (ACTH) and corticosteroid treatment in children with epilepsy other than infantile spasms.
* Meta-analysis based on aggregate data from 2 controlled prospective, 5 uncontrolled prospective, and 31 retrospective studies.
* Pooled data showing a seizure response in 60% and electroencephalography (EEG) response in 56% of patients, with no major differences between drugs. However, 30%–40% of patients relapse after the cessation of treatment.
* The most frequent adverse effects are obesity and Cushing's syndrome, occurring in 70% of patients under continuous treatment for some weeks, but in less than 10% undergoing pulsed, intermittent regimens.
* More prospective, randomized-controlled studies are needed to improve the level of evidence and define the optimal doses and treatment duration.
Viruses that carry a positive-sense, single-stranded (+ssRNA) RNA translate their genomes soon after entering the host cell to produce viral proteins, with the exception of retroviruses. A distinguishing feature of retroviruses is reverse transcription, where the +ssRNA genome serves as a template to synthesize a double-stranded DNA copy that subsequently integrates into the host genome. As retroviral RNAs are produced by the host cell transcriptional machinery and are largely indistinguishable from cellular mRNAs, we investigated the potential of incoming retroviral genomes to directly express proteins. Here we show through multiple, complementary methods that retroviral genomes are translated after entry. Our findings challenge the notion that retroviruses require reverse transcription to produce viral proteins. Synthesis of retroviral proteins in the absence of productive infection has significant implications for basic retrovirology, immune responses and gene therapy applications.
Bipolar disorder (BD) is a heritable mental illness with complex etiology. While the largest published genome-wide association study identified 64 BD risk loci, the causal SNPs and genes within these loci remain unknown. We applied a suite of statistical and functional fine-mapping methods to these loci, and prioritized 22 likely causal SNPs for BD. We mapped these SNPs to genes, and investigated their likely functional consequences by integrating variant annotations, brain cell-type epigenomic annotations, brain quantitative trait loci, and results from rare variant exome sequencing in BD. Convergent lines of evidence supported the roles of SCN2A, TRANK1, DCLK3, INSYN2B, SYNE1, THSD7A, CACNA1B, TUBBP5, PLCB3, PRDX5, KCNK4, AP001453.3, TRPT1, FKBP2, DNAJC4, RASGRP1, FURIN, FES, YWHAE, DPH1, GSDMB, MED24, THRA, EEF1A2, and KCNQ2 in BD. These represent promising candidates for functional experiments to understand biological mechanisms and therapeutic potential. Additionally, we demonstrated that fine-mapping effect sizes can improve performance and transferability of BD polygenic risk scores across ancestrally diverse populations, and present a high-throughput fine-mapping pipeline (https://github.com/mkoromina/SAFFARI).
Human feline leukaemia virus subgroup C receptor-related proteins 1 and 2 (FLVCR1 and FLVCR2) are members of the major facilitator superfamily1. Their dysfunction is linked to several clinical disorders, including PCARP, HSAN and Fowler syndrome2,3,4,5,6,7. Earlier studies concluded that FLVCR1 may function as a haem exporter8,9,10,11,12, whereas FLVCR2 was suggested to act as a haem importer13, yet conclusive biochemical and detailed molecular evidence remained elusive for the function of both transporters14,15,16. Here, we show that FLVCR1 and FLVCR2 facilitate the transport of choline and ethanolamine across the plasma membrane, using a concentration-driven substrate translocation process. Through structural and computational analyses, we have identified distinct conformational states of FLVCRs and unravelled the coordination chemistry underlying their substrate interactions. Fully conserved tryptophan and tyrosine residues form the binding pocket of both transporters and confer selectivity for choline and ethanolamine through cation–π interactions. Our findings clarify the mechanisms of choline and ethanolamine transport by FLVCR1 and FLVCR2, enhance our comprehension of disease-associated mutations that interfere with these vital processes and shed light on the conformational dynamics of these major facilitator superfamily proteins during the transport cycle.
Background: A good physician should be empathic and altruistic, among other qualities. Therefore, the levels of socially undesirable personality traits (Dark Triad) as well as implicit motives of achievement, affiliation and power (Multi-Motive Grid) among medical students as future physicians were analyzed at two different points in their medical training.
Methods: This study includes 380 medical students in their first year and 217 in their third year in Germany. All participants completed the Dirty Dozen (DD) and Multi-Motive Grid (MMG) questionnaires at the end of two different classes as paper-and-pencil tests. Relevant differences of the Dark Triad traits between the medical students and reference sample and the two different cohorts, as well as their implicit motives, the associations of Dark Triad traits and MMG components and gender differences of the Dark Triad traits were calculated.
Results: There were no significant group differences between year one and year three medical students in narcissism, psychopathy and Machiavellianism (Dark Triad). There were no significant differences between the medical students and reference sample except in psychopathy. Male students scored significantly higher in the Dark Triad traits than female students. In the MMG, first-year students scored significantly higher levels in Fear of Rejection, and lower levels in Hope of Success and Hope of Power than the third-year students. Some associations were found between narcissism and Machiavelliansim with Hope of Success, Hope of Power and Fear of power.
Conclusions: Dark Triad traits already appear to exist before the commencement of medical studies. These traits do not differ significantly between the medical students and reference sample; only a few MMG components seem to differ at different stages of their studies. This lack of differences between the medical students and validation cohort indicates that tests based on (undesirable) personality traits are not suitable criteria for the admission selection of medical students.
Hematopoietic mutations in epigenetic regulators like DNA methyltransferase 3 alpha (DNMT3A), play a pivotal role in driving clonal hematopoiesis of indeterminate potential (CHIP), and are associated with unfavorable outcomes in patients suffering from heart failure (HF). However, the precise interactions between CHIP-mutated cells and other cardiac cell types remain unknown. Here, we identify fibroblasts as potential partners in interactions with CHIP-mutated monocytes. We used combined transcriptomic data derived from peripheral blood mononuclear cells of HF patients, both with and without CHIP, and cardiac tissue. We demonstrate that inactivation of DNMT3A in macrophages intensifies interactions with cardiac fibroblasts and increases cardiac fibrosis. DNMT3A inactivation amplifies the release of heparin-binding epidermal growth factor-like growth factor, thereby facilitating activation of cardiac fibroblasts. These findings identify a potential pathway of DNMT3A CHIP-driver mutations to the initiation and progression of HF and may also provide a compelling basis for the development of innovative anti-fibrotic strategies.
The human immune system is determined by the functionality of the human lymph node. With the use of high-throughput techniques in clinical diagnostics, a large number of data is currently collected. The new data on the spatiotemporal organization of cells offers new possibilities to build a mathematical model of the human lymph node - a virtual lymph node. The virtual lymph node can be applied to simulate drug responses and may be used in clinical diagnosis. Here, we review mathematical models of the human lymph node from the viewpoint of cellular processes. Starting with classical methods, such as systems of differential equations, we discuss the values of different levels of abstraction and methods in the range from artificial intelligence techniques formalism.
Highlights
• Constrictional structures range from dome-and-basin folds to coeval folds and boudins.
• Under bulk constriction, the competent layer rotates slower than a passive plane.
• Extension-parallel and –perpendicular folds grow simultaneously.
• Extension-perpendicular folds affect previous boudins.
Abstract
We conducted scaled analogue modelling to show the influence of varying single layer initial orientation on the geometry of folds and boudins in a bulk constrictional strain field. The initial angle between the plane of shortening and the competent layer (θZ(i)) was incrementally increased from 0° to 90° by multiples of 11.25°. While the amount of layer thickening decreased with increasing θZ(i), the deformation structures produced range from pure dome-and-basin folds to coeval folds and boudins. Based on the attitude of fold axes, there are extension-parallel (FEPR) and extension-perpendicular (FEPP) folds, with axes subparallel and subperpendicular to the principal stretching axis (X), respectively. Coeval growth of FEPR folds and boudins occurred when θZ(i) > ca. 25°. The FEPP folds can be subdivided into a first type which affect the entire layer (if θZ(i) ranges between 11.25 and 78.75°) and a second type, referred to as FBEPP folds, which are affecting pre-existing boudins if θZ(i) > 45°. The interlimb angle of all types of folds increases with increasing θZ(i). Folds and boudins similar to the ones produced in this study can be found in salt domes and in tectonites of subduction zones.
Background: Trauma-related guilt and shame are crucial for the development and maintenance of PTSD (posttraumatic stress disorder). We developed an intervention combining cognitive techniques with loving-kindness meditations (C-METTA) that specifically target these emotions. C-METTA is an intervention of six weekly individual treatment sessions followed by a four-week practice phase.
Objective: This study examined C-METTA in a proof-of-concept study within a randomized wait-list controlled trial.
Method: We randomly assigned 32 trauma-exposed patients with a DSM-5 diagnosis to C-METTA or a wait-list condition (WL). Primary outcomes were clinician-rated PTSD symptoms (CAPS-5) and trauma-related guilt and shame. Secondary outcomes included psychopathology, self-criticism, well-being, and self-compassion. Outcomes were assessed before the intervention phase and after the practice phase.
Results: Mixed-design analyses showed greater reductions in C-METTA versus WL in clinician-rated PTSD symptoms (d = −1.09), guilt (d = −2.85), shame (d = −2.14), psychopathology and self-criticism.
Conclusion: Our findings support positive outcomes of C-METTA and might contribute to improved care for patients with stress-related disorders. The study was registered in the German Clinical Trials Register (DRKS00023470).
HIGHLIGHTS
C-METTA is an intervention that addresses trauma-related guilt and shame and combines cognitive interventions with loving-kindness meditations.
A proof-of-concept study was conducted examining C-METTA in a wait-list randomized controlled trial
C-METTA led to reductions in trauma-related guilt and shame and PTSD symptoms.
Targeted protein degradation (TPD) has recently emerged as an exciting new drug modality. However, the strategy of developing small molecule-based protein degraders has evolved over the past two decades and has now established molecular tags that are already in clinical use, as well as chimeric molecules, PROteolysis TArgeting Chimeras (PROTACs), based mainly on ligand systems developed for the two E3 ligases CRBN and VHL. The large size of the human E3 ligase family suggests that PROTACs can be developed by targeting a large diversity of E3 ligases, some of which have restricted expression patterns with the potential to design disease- or tissue-specific degraders. Indeed, many new E3 ligands have been published recently, confirming the druggability of E3 ligases. This review summarises recent data on E3 ligases and highlights the challenges in developing these molecules into efficient PROTACs rivalling the established degrader systems.
Background: Despite known clinical benefits, guideline-recommended heart rate (HR) control is not achieved for a significant proportion of patients with HF with reduced ejection fraction. The wearable cardioverter-defibrillator (WCD) provides continuous HR monitoring and alerts that could aid medication titration.
Objective: This study sought to evaluate sex differences in achieving guideline-recommended HR control during a period of WCD use.
Methods: Data from patients fitted with a WCD from 2015 to 2018 were obtained from the manufacturer’s database (ZOLL). The proportion of patients with adequate nighttime resting HR control at the beginning of use (BOU) and at the end of use (EOU) were compared by sex. Adequate HR control was defined as having a nighttime median HR <70 beats/min.
Results: A total of 21,440 women and a comparative sample of 17,328 men (median 90 [IQR 59–116] days of WCD wear) were included in the final dataset. Among patients who did not receive a shock, over half had insufficient HR control at BOU (59% of women, 53% of men). Although the proportion of patients with resting HR ≥70 beats/min improved by EOU, 43% of women and 36% of men did not achieve guideline-recommended HR control.
Conclusion: A significant proportion of women and men did not achieve adequate HR control during a period of medical therapy optimization. Compared with men, a greater proportion of women receiving WCD shocks had insufficiently controlled HR in the week preceding ventricular tachyarrhythmia/ventricular fibrillation and 43% of nonshocked women, compared with 36% of men, did not reach adequate HR control during the study period. The WCD can be utilized as a remote monitoring tool to record HR and inform adequate uptitration of beta-blockers, with particular focus on reducing the treatment gap in women.
Evidence-based and comprehensible health information is a key element of evidence-based medicine and public health. The goal is informed decision-making based on realistic estimations of health risks and accurate expectations about benefits and harms of interventions. In Germany, standards of evidence-based risk information were poorly followed during the COVID-19 pandemic. Frequently, public information was biased, fragmentary and misleading. Pandemic-related threat scenarios induced emotional distress and unnecessary anxiety. A systematic and comprehensive evaluation of the pandemic measures is crucial, but still pending in Germany. A critical analysis of risk communication by experts, politicians and the media during the pandemic should be a key element of the evaluation process. Evaluation of decision making and media reporting during the pandemic should improve preparedness for future crises.
Background: Urachal cancer (UrC) is a rare disease with limited availability of representative incidence and clinical data. Although, the prevalence is accounting for less than 1% of bladder tumors, the 5-year survival rate is around only 50% for patients with resectable tumors, and even worse for patients with metastatic disease. Due to the lack of comprehensive prospective studies, our current knowledge of UrC is still limited.
Objective: The present study aimed to summarize the available registry-based studies with unselected UrC patients to evaluate its incidence and clinicopathological characteristics.
Material and methods: We conducted a systematic literature search of registry-based UrC publications on the 15th of May 2023 in 5 databases, which identified 4,748 publications. After duplicate removal and selection by 2 independent investigators, 6 publications proved to be appropriate for the final meta-analysis. Estimated incidence and clinicopathological parameters were extracted.
Results: Estimated incidence ranged between 0.022 and 0.060/ 100.000 person-years, with the highest occurrence in Japan and the lowest in Canada, while the random effect model calculated an overall incidence rate of 0.04 (95%CI: 0.03–0.05) 100.000 person-years. The median age at first diagnosis was 60 years (range: 58–64). The female to male ratio was 2:3. Lymph node or distant metastases were present in 9% and 14% of patients. The predominant tumour type was adenocarcinoma (86%) followed by urothelial carcinoma (12%) and squamous cell carcinoma (2%). The 5-year survival rate was 51.0% with 95%CI: 45.2–57.4.
Conclusions: Our study provides an up-to-date comparison of estimated incidence rates between 6 countries of 3 continents based on rigorously selected registry-based studies. The results suggest low incidence rates for UrC with considerable geographic differences. The present meta-analysis provides unbiased registry-based data on the incidence, clinicopathological parameters and survival of UrC.
The ICH M13A draft bioequivalence guideline allows the exclusion of very low plasma profiles from the statistical evaluation in exceptional cases, i.e., if such phenomenon occurs due to non-compliance of subjects (not swallowing the product). Moreover, the draft ICH guideline requests additional bioequivalence studies for medicinal products with pH-dependent solubility after concomitant administration of gastric pH modifying preparations, e.g., proton pump inhibitors. Both regulations are scientifically sound, however, would need further specification. Main problem in this context is that compounds with very low solubility and slow intrinsic dissolution in the intestinal environment will cause significant bioavailability problems if their solid oral dosage forms are emptied from the stomach undisintegrated. Also very low plasma profiles may result under these circumstances. Such cases can occur accidentally and are not resultant of non-compliance. Thus, limitation for one case per study only as suggested in the guideline is not justified.
Background: The Association of the Scientific Medical Societies in Germany (AWMF) clinical practice guideline on cochlear implant (CI) treatment, which was updated in 2020, defined the entire process of CI care for the first time. In the present study, the feasibility and results of very early rehabilitation were examined.
Materials and methods: The intervention group (IG) comprised 54 patients in whom rehabilitation was initiated within 14 (maximally 28) days after implantation. Patients with a significantly longer waiting time were included in the control group (CG, n = 21). In addition to the start and duration of rehabilitation, the speech intelligibility achieved with CI was recorded at different timepoints within a 12-month period. In addition, questionnaires were used to assess the effort of fitting the CI processor and the patients’ satisfaction with the outcome as well as the timing of the start of rehabilitation.
Results: Median waiting time between implantation and start of rehabilitation was 14 days in the IG and 106 days in the CG; 92.6% of IG patients were able to start rehabilitation within 14 days. The effect of rehabilitation in the IG was 35 and in the CG 25 percentage points (Freiburg monosyllabic test). After 6 and 12 months of CI use, both groups showed comparable results in the test condition in quiet (IG/CG 6 months: 70%/70%; 12 months: 70%/60%, Freiburg monosyllabic test) and in noise (IG/CG 6 months: −1.1 dB SNR/–0.85 dB SNR; 12 months: −0.65 dB SNR/+0.3 dB SNR, Oldenburg sentence test). Hearing quality assessment scores collected by SSQ (Speech, Spatial and Qualities of Hearing Scale) questionnaire showed better scores in the IG at 6 months, which converged to CG scores at 12 months. The IG was significantly more satisfied with the timing of the start of rehab than the CG. All other data obtained from questionnaires showed no differences between the two groups.
Conclusion: A very early start of inpatient rehabilitation after cochlear implantation was successfully implemented. The rehabilitation was completed within 7 weeks of CI surgery. Comparison of speech recognition test results before and after rehabilitation showed a significant improvement. A clear rehabilitation effect can therefore be demonstrated. Inclusion of CI rehabilitation in the German catalog of follow-up treatments is thus scientifically justified and therefore strongly recommended.
Therapierefraktärer Schmerz ist ein weit verbreitetes, äußerst belastendes Leitsymptom rheumatischer Erkrankungen. Viele Betroffene weichen daher bei Versagen der Standardmedikation selbstständig auf Cannabis oder die strukturell verwandte Substanz Palmitoylethanolamid (PEA) als Add-On- oder Alternativtherapie aus, obwohl dies in Deutschland bisher nur eingeschränkt zulässig ist. Die deutsche Gesetzgebung ist diesbezüglich nicht eindeutig, weshalb Ärzt:innen in ihrer Entscheidung, Cannabis zu verschreiben, auf Leitlinien, Fallberichte und Expert:innenmeinungen zurückgreifen müssen. Dies führt zu schwierigen Einzelfallentscheidungen, da sich die derzeitige Datenlage zu Cannabis-based Medicine (CBM) bzw. PEA und Rheuma als mangelhaft darstellt und die Leitlinien dementsprechend keine klaren Empfehlungen enthalten. Ziel der vorliegenden Arbeit ist es, die vorhandene Evidenz zusammenzufassen, zu ordnen und anhand der Hill-Kriterien den möglichen kausalen Zusammenhang zwischen der Einnahme von CBM bzw. PEA und der analgetischen Wirkung bei Rheumaschmerzen zu prüfen.
Background: Novel treatments are needed to control refractory status epilepticus (SE). This study aimed to assess the potential effectiveness of fenfluramine (FFA) as an acute treatment option for SE. We present a summary of clinical cases where oral FFA was used in SE.
Methods: A case of an adult patient with Lennox–Gastaut syndrome (LGS) who was treated with FFA due to refractory SE is presented in detail. To identify studies that evaluated the use of FFA in SE, we performed a systematic literature search.
Results: Four case reports on the acute treatment with FFA of SE in children and adults with Dravet syndrome (DS) and LGS were available. We report in detail a 30-year-old woman with LGS of structural etiology, who presented with generalized tonic and dialeptic seizures manifesting at high frequencies without a return to clinical baseline constituting the diagnosis of SE. Treatment with anti-seizure medications up to lacosamide 600 mg/d, brivaracetam 300 mg/d, valproate 1,600 mg/d, and various benzodiazepines did not resolve the SE. Due to ongoing refractory SE and following an unremarkable echocardiography, treatment was initiated with FFA, with an initial dose of 10 mg/d (0.22 mg/kg body weight [bw]) and fast up-titration to 26 mg/d (0.58 mg/kg bw) within 10 days. Subsequently, the patient experienced a resolution of SE within 4 days, accompanied by a notable improvement in clinical presentation and regaining her mobility, walking with the assistance of physiotherapists. In the three cases reported in the literature, DS patients with SE were treated with FFA, and a cessation of SE was observed within a few days. No treatment-emergent adverse events were observed during FFA treatment in any of the four cases.
Conclusions: Based on the reported cases, FFA might be a promising option for the acute treatment of SE in patients with DS and LGS. Observational data show a decreased SE frequency while on FFA, suggesting a potentially preventive role of FFA in these populations.
Key points
* We summarize four cases of refractory status epilepticus (SE) successfully treated with fenfluramine.
* Refractory SE resolved after 4–7 days on fenfluramine.
* Swift fenfluramine up-titration was well-tolerated during SE treatment.
* Treatment-emergent adverse events on fenfluramine were not observed.
* Fenfluramine might be a valuable acute treatment option for SE in Dravet and Lennox–Gastaut syndromes.
MicroRNAs (miRNAs) are critical post-transcriptional regulators in many biological processes. They act by guiding RNA-induced silencing complexes to miRNA response elements (MREs) in target mRNAs, inducing translational inhibition and/or mRNA degradation. Functional MREs are expected to predominantly occur in the 3’ untranslated region and involve perfect base-pairing of the miRNA seed. Here, we generate a high-resolution map of miR-181a/b-1 (miR-181) MREs to define the targeting rules of miR-181 in developing murine T-cells. By combining a multi-omics approach with computational high-resolution analyses, we uncover novel miR-181 targets and demonstrate that miR-181 acts predominantly through RNA destabilization. Importantly, we discover an alternative seed match and identify a distinct set of targets with repeat elements in the coding sequence which are targeted by miR-181 and mediate translational inhibition. In conclusion, deep profiling of MREs in primary cells is critical to expand physiologically relevant targetomes and establish context-dependent miRNA targeting rules.
Key Points:
* Deep profiling identifies novel targets of miR-181 associated with global gene regulation.
* miR-181 MREs in repeat elements in the coding sequence act through translational inhibition.
* High-resolution analysis reveals an alternative seed match in functional MREs.
Understanding the underlying mechanisms that link psychopathology and physical comorbidities in schizophrenia is crucial since decreased physical fitness and overweight pose major risk factors for cardio-vascular diseases and decrease the patients’ life expectancies. We hypothesize that altered reward anticipation plays an important role in this. We implemented the Monetary Incentive Delay task in a MR scanner and a fitness test battery to compare schizophrenia patients (SZ, n = 43) with sex- and age-matched healthy controls (HC, n = 36) as to reward processing and their physical fitness. We found differences in reward anticipation between SZs and HCs, whereby increased activity in HCs positively correlated with overall physical condition and negatively correlated with psychopathology. On the other handy, SZs revealed stronger activity in the posterior cingulate cortex and in cerebellar regions during reward anticipation, which could be linked to decreased overall physical fitness. These findings demonstrate that a dysregulated reward system is not only responsible for the symptomatology of schizophrenia, but might also be involved in physical comorbidities which could pave the way for future lifestyle therapy interventions.
Spezialwissen für SCALE
(2024)
Volker Zickermann und Eric Helfrich sind bei der Exzellenzcluster-Initiative SCALE (Subcellular Architecture of Life) dabei und werden dort ihre Expertise einbringen. Das Spezialgebiet des einen ist ein Proteinkomplex in den Mitochondrien, den Kraftwerken der Zelle. Der andere sucht schwerpunktmäßig bisher unbekannte Naturstoffe, die die Basis für neue Antibiotika sein könnten.
Herzforschung meets KI
(2024)
Moderne Methoden der Künstlichen Intelligenz (KI) spielen in der Wissenschaft eine immer größere Rolle. Wie Forscher des Exzellenzclusters Cardio-Pulmonary Institute (CPI) KI in der Herzbildgebung nutzen, zeigte Professor Eike Nagel im Rahmen der Bürgeruniversität der Goethe-Universität. Er leitet das Institut für experimentelle und translationale kardiovaskuläre Bildgebung am Fachbereich Medizin und forscht an der Entwicklung verbesserter Behandlungsmöglichkeiten für Herz-Kreislauf-Erkrankungen. Mit dem Ziel, seine Forschung für alle Menschen zugänglich und verständlicher zu machen, lud Prof. Nagel interessierte Bürger*innen am 10. Mai in sein Institut ein.
Lifestyle factors—such as diet, physical activity (PA), smoking, and alcohol consumption—have a significant impact on mortality as well as healthcare costs. Moreover, they play a crucial role in the development of type 2 diabetes mellitus (DM2). There also seems to be a link between lifestyle behaviours and insulin resistance, which is often a precursor of DM2. This study uses an enhanced Healthy Living Index (HLI) integrating accelerometric data and an Ecological Momentary Assessment (EMA) to explore differences in lifestyle between insulin-sensitive (IS) and insulin-resistant (IR) individuals. Moreover, it explores the association between lifestyle behaviours and inflammation. Analysing data from 99 participants of the mPRIME study (57 women and 42 men; mean age 49.8 years), we calculated HLI scores—ranging from 0 to 4— based on adherence to specific low-risk lifestyle behaviours, including non-smoking, adhering to a healthy diet, maximally moderate alcohol consumption, and meeting World Health Organization (WHO) PA guidelines. Insulin sensitivity was assessed using a Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) and C-reactive protein (CRP) levels were used as a proxy for inflammation. Lifestyle behaviours, represented by HLI scores, were significantly different between IS and IR individuals (U = 1529.0; p = 0.023). The difference in the HLI score between IR and IS individuals was mainly driven by lower adherence to PA recommendations in the IR group. Moreover, reduced PA was linked to increased CRP levels in the IR group (r = −0.368, p = 0.014). Our findings suggest that enhancing PA, especially among individuals with impaired insulin resistance, holds significant promise as a preventive strategy.
Although, during the past decades, substantial advances emerged in identifying major local and systemic factors contributing to initiation and progression of osteoarthritis (OA), some neuroendocrine mechanisms are still not understood or even neglected when thinking about novel therapeutic options. One of which is the sympathetic nervous system that exhibits various OA-promoting effects in different tissues of the joint. Interestingly, the β2-adrenoceptor (AR) mediates the majority of these effects as demonstrated by several in vitro, in vivo as well as in clinical studies. This review article does not only summarize studies of the past two decades demonstrating that the β2-AR plays an OA-promoting role in different tissues of the joint but also aims to encourage the reader to think about next-level research to discover novel and innovative preventive and/or therapeutic strategies targeting the β2-AR in OA.
Hintergrund: Mit der im Jahr 2020 aktualisierten AWMF-Leitlinie zur Versorgung mit einem Cochleaimplantat (CI) wurde erstmals der gesamte Prozess einer CI-Versorgung definiert. In der vorliegenden Studie wurden die Machbarkeit und die Ergebnisse einer sehr frühen Rehabilitationsmaßnahme (Reha) untersucht.
Methodik: Es wurden 54 Patienten in die Interventionsgruppe (IG) eingeschlossen, bei der die Reha innerhalb von 14 (maximal 28) Tagen nach der Implantation eingeleitet wurde. In eine Kontrollgruppe (KG, n = 21) wurden Patienten mit deutlich längerer Wartezeit eingeschlossen. Neben dem Beginn und der Dauer der Reha wurde das mit CI erreichte Sprachverstehen zu verschiedenen Zeitpunkten innerhalb von 12 Monaten erfasst. Zusätzlich wurde mit Fragebögen der Aufwand der Anpassung des CI-Prozessors und die Zufriedenheit der Patienten mit dem Ergebnis sowie dem Zeitpunkt des Beginns der Reha ermittelt.
Ergebnisse: Die Wartezeit zwischen Implantation und Beginn der Reha lag in der IG bei 14 Tagen und in der KG bei 106 Tagen (Mediane). Es konnten 92,6 % der Patienten der IG die Reha innerhalb von 14 Tagen antreten. Der Effekt der Reha lag in der IG bei 35 und in der KG bei 25 Prozentpunkten (Freiburger Einsilbertest). Nach 6 und 12 Monaten (M) CI-Nutzung zeigten beide Gruppen sowohl in der Testbedingung in Ruhe (IG/KG 6M: 70 %/70 %; 12M: 70 %/60 %, Freiburger Einsilbertest) als auch im Störgeräusch (IG/KG 6M: −1,1 dB SNR/–0,85 dB SNR; 12M: −0,65 dB SNR/+0,3 dB SNR, Oldenburger Satztest) vergleichbare Ergebnisse. Die mittels des Fragebogens Speech, Spatial and Qualities of Hearing Scale (SSQ) erfassten Ergebnisse für die Einschätzung der Hörqualität zeigten nach 6 Monaten eine bessere Bewertung in der IG, die sich nach 12 Monaten an die Ergebnisse der KG anglich. Die IG war mit dem Zeitpunkt des Beginns der Reha deutlich zufriedener als die KG. Alle anderen aus Fragebögen ermittelten Daten zeigten keine Unterschiede zwischen den beiden Gruppen.
Schlussfolgerung: Der sehr frühe Beginn einer stationären Reha nach Cochleaimplantation ist erfolgreich umsetzbar. Die Reha konnte innerhalb von 7 Wochen nach der Implantation abgeschlossen werden. Der Vergleich der Ergebnisse der Tests des Sprachverstehens vor und nach der Reha zeigte eine deutliche Steigerung. Somit ist ein deutlicher Reha-Effekt nachweisbar. Die Aufnahme der CI-Rehabilitation in den Katalog der Anschlussheilbehandlungen ist somit wissenschaftlich begründet und damit dringend zu empfehlen.
Highlights
• CD62p + exosomes were significantly increased in septic polytrauma-patients, while CD40+, as well as CD49e + exosomes were diminished.
• Exosomal IL-6 concentration in septic patients reflects the systemic IL-6.
• Exosomal IL-10 concentration seemed to be constant in patients and healthy controls.
• Decrease of miR-21 in exosomes was associated with the development of sepsis, while exosomal miR-93, miR-155 and miR-92a were not specifically altered.
Abstract
Sepsis as a severe systemic inflammation leads oftentimes to organ dysfunction and subsequently to death. In polytrauma patients, septic complications represent with 45% the predominant cause of late death and are responsible for extremely high costs in the healthcare system. Therefore, clinicians have to detect as early as possible the begin of sepsis to improve the patient's outcome. One new promising diagnostic tool to diagnose septic complications in polytraumatized patients are exosomes.
Plasma samples from polytraumatized patients (Injury Severity Score (ISS) ≥16) which developed sepsis (n = 10) and without sepsis (n = 10), were collected at emergency room (ER), 24h and 5 days after trauma. The EVs subpopulations were investigated by a bead-based multiplex flow cytometry measurement of surface epitopes and were compared with plasma EVs from healthy controls (n = 10). Moreover, exosomal cytokine concentrations were measured via high-sensitive ELISA and were correlated with systemic concentrations. For miRNA cargo analysis, we analysed the miRNAs miR-1298-5p, miR-1262, miR-125b-5p, miR-92a-3p, miR-93-5p, miR-155-5p and miR-21-5p and compared their exosomal concentrations by means of RT-qPCR.
CD62p + exosomes were significantly increased in septic polytrauma-patients (p ≤ 0.05), while CD40+exosomes, as well as CD49e + exosomes were diminished (p ≤ 0.05). Furthermore, we observed that the exosomal IL-6 concentration reflects the systemic IL-6 concentration (r2 = 0.63) and did not significantly alter between patients with and without sepsis. The exosomal IL-10 concentration seemed to be constant in all patients and healthy controls. We observed that a decrease of miR-21-5p in exosomes was associated with the development of sepsis (p ≤ 0.05), while exosomal miR-93-5p, miR-155-5p and miR-92a-3p were not specifically altered in septic patients.
Taken together, the present study in polytraumatized patients demonstrated that the development of sepsis is associated with an increase of CD62p + exosomes. Furthermore, the exosomal cargo was changed in septic patients: miR-21-5p was diminished.
Die vorliegende Arbeit behandelt den Vergleich zweier Geräte - „Endotrust MiFusion TLS 2“ und „Medtronic LigaSure Maryland System“ - zur endoskopischen Entnahme der Arteria radialis (RA) zur Verwendung als Bypass-Gefäß in der Herzchirurgie.
Grundsätzlich kommen in der Bypass-Chirurgie zur Herstellung eines Free-Grafts am Herzen neben der Verwendung der Thoraxarterien die Vena Saphena Magna (VSM) sowie die RA in Frage. In den aktuellen europäischen Leitlinien zur Behandlung von hochgradigen Stenosen wird die Verwendung der RA empfohlen („Class 1 Level B“-Empfehlung).
Die Frage, ob die RA für den Einsatz als Bypass-Gefäß offen oder endoskopisch entnommen werden sollte, ist in der Literatur weiterhin umstritten. In den aktuellen Leitlinien zur Behandlung von koronaren Herzkrankheiten wird aufgrund dieser insoweit uneindeutigen Studienlage keine Empfehlung ausgesprochen. Trotzdem ist die endoskopische Entnahme der RA im klinischen Alltag mittlerweile etabliert. Im Kontext dieser uneindeutigen Studienlage einerseits und der praktischen Bedeutung endoskopischer Entnahme andererseits ist es Zielsetzung der vorliegenden Arbeit, durch einen Gerätevergleich einen Beitrag zur Optimierung der endoskopischen Operationstechnik zu leisten. Es soll zudem aufgezeigt werden, inwieweit die endoskopische Entnahme der RA ein sicheres und effizientes Verfahren darstellt.
In der Literatur zum Vergleich von Operationstechniken zur Entnahme von Bypass-Gefäßen werden häufig histologische Untersuchungen angewendet. Diese ermöglichen eine zeitnahe Beurteilung der Qualität des entnommenen Grafts. Das ist auch in dieser Arbeit der wesentliche Grund dafür, dass die histologische Beurteilung der Qualität der RA als primärer Endpunkt angewendet wird. In Anlehnung an die Literatur wurde die strukturelle Integrität des Endothels und der Elastica interna beurteilt. Die histologische Beurteilung erfolgte nach Immunfluoreszenz-Bearbeitung der Proben.
Im Einklang mit der bestehenden Literatur zur Frage, ob die RA offen oder endoskopisch entnommen werden sollte, wurde in dieser Studie als sekundäre Endpunkte Kriterien bezüglich der Sicherheit und Effizienz der Entnahme verwendet. Dies betrifft das Auftreten von intra- und postoperativen Komplikationen, insbesondere im Hinblick auf neurologische Beeinträchtigungen am operierten Arm, sowie die Entnahmedauer und den operativen Aufwand zur Blutstillung.
Die in dieser Arbeit behandelte Studie wurde als prospektive, 1:1 randomisierte Studie mit zwei Gruppen mit jeweils 50 Patienten durchgeführt. Alle Operationen erfolgten im Zeitraum Januar 2017 bis Juli 2017 im Herzzentrum der Kerckhoff-Klinik Bad Nauheim.
Bezüglich der Resultate des Gerätevergleichs zeigte sich ein eindeutiges Ergebnis. Sämtliche Beurteilungskriterien, bei denen signifikante Unterschiede zwischen den beiden Gruppen aufgetreten sind, u.a. Integrität der Elastica interna, Entnahmedauer, Vorkommen von Residualblutungen, Auftreten von sensorischen Störungen fallen zugunsten des LigaSure-Systems aus.
Dabei ist unserer Meinung nach der wichtigste Einzelaspekt, dass die histologisch ermittelte Integrität der Elastica interna als Indikator für die Qualität des entnommen Grafts in der LigaSure-Gruppe signifikant besser war als in der MiFusion-Gruppe. Dagegen konnten aus der histologischen Untersuchung des Endothels keine klaren Rückschlüsse gezogen werden. Insofern besteht Unsicherheit, ob die Schädigung der Endothelschicht durch die Entnahme selbst oder durch die anschließende Präparierung der entnommenen Proben verursacht wurde.
Bezüglich der sekundären Endpunkte zeigten sich für die Mifusion-Patientengruppe im Vergleich zu anderen Studien zur endoskopischen Entnahme der RA zufriedenstellende bis gute und für die LigaSure Gruppe gute bis sehr gute Ergebnisse. Unabhängig vom verwendeten Gerät kann diese Studie deshalb als eine Bestätigung bisheriger Studien zur Vorteilhaftigkeit der endoskopischen RA-Entnahme angesehen werden. Letztlich fehlt jedoch weiterhin der Nachweis, dass eine endoskopische Entnahme unbedenklich im Hinblick auf den langfristigen kardiologischen Outcome ist. Dies bleibt zukünftiger Forschung vorbehalten.
Darüber hinaus trägt die Studie dazu bei, das klinische Erfahrungswissen über operationstechnische Details bei der Entnahme der Radialarterie zu erweitern und somit die Akzeptanz für die Verwendung der Radialarterie als Bypass-Gefäß in der koronaren Herzchirurgie zu verbessern.
Highlights
• It is important to distinguish acute provoked seizures due to autoimmune encephalitis from chronic unprovoked seizures due to autoimmune-associated epilepsy.
• Currently it is hardly possible in an individual AIE/ALE/RE patient to separate acute provoked seizures from chronic unprovoked seizures due to limitations in determining seizure outcomes, unclear time courses, potential causal interactions between both seizure origins, compartmentalized immune-inflammation, and a lack of licensed drugs to reliably resolve immune-inflammation in the brain parenchyma.
• This makes it hard to decide when to terminate ASMs and to counsel the individual patient regarding driving abilities and other behavioral restrictions and recommendations.
• Studies are urgently needed to define clinical and paraclinical biomarkers in a hypothesis-free, data-driven approach reliably predicting (or not) the development of AAE and the cognitive and behavioral outcome in the due course of an individual patient´s disease.
• These studies should be experimentally validated in suitable animal models.
Abstract
The current International League Against Epilepsy (ILAE) definition and classification guidelines for the first time introduced the category of immune-mediated focal epilepsy in addition to structural, genetic, infectious, and metabolic aetiologies. Moreover, the ILAE Autoimmunity and Inflammation Taskforce recently provided a conceptual framework for the distinction between acute “provoked” seizures in the acute phase of autoimmune encephalitis from chronic “unprovoked” seizures due to autoimmune-associated epilepsy. The first category predominately applies to those autoimmune encephalitis patients with autoantibodies against cell surface neural antigens, in whom autoantibodies are assumed to exert a direct ictogenic effect without overt structural damage. These patients do not exhibit enduring predisposition to seizures after the “acute phase” encephalitis, and thus do not fulfil the definition of epilepsy. The second category applies to those autoimmune encephalitis patients with autoantibodies against intracellular neural antigens and Rasmussen's encephalitis, in whom T cells are assumed to cause epileptogenic effects through immune-inflammation and overt structural damage. These patients do exhibit enduring predisposition to seizures after the “acute phase” of encephalitis and thus fulfil the definition of epilepsy. AAE may result from both, ongoing brain autoimmunity and associated structural brain damage according to the current ILAE definition and classification guideline. We here discuss the shortcomings and defaults of this concept and suggest an unbiased translationally validated and data-driven approach to predict in an individual encephalitis patient the propensity to develop (or not) AAE and the cognitive and behavioural outcome.
Tight control over transcription factor activity is necessary for a sensible balance between cellular proliferation and differentiation in the embryo and during tissue homeostasis by adult stem cells, but mechanistic details have remained incomplete. The homeodomain transcription factor MEIS2 is an important regulator of neurogenesis in the ventricular–subventricular zone (V-SVZ) adult stem cell niche in mice. We here identify MEIS2 as direct target of the intracellular protease calpain-2 (composed of the catalytic subunit CAPN2 and the regulatory subunit CAPNS1). Phosphorylation at conserved serine and/or threonine residues, or dimerization with PBX1, reduced the sensitivity of MEIS2 towards cleavage by calpain-2. In the adult V-SVZ, calpain-2 activity is high in stem and progenitor cells, but rapidly declines during neuronal differentiation, which is accompanied by increased stability of MEIS2 full-length protein. In accordance with this, blocking calpain-2 activity in stem and progenitor cells, or overexpression of a cleavage-insensitive form of MEIS2, increased the production of neurons, whereas overexpression of a catalytically active CAPN2 reduced it. Collectively, our results support a key role for calpain-2 in controlling the output of adult V-SVZ neural stem and progenitor cells through cleavage of the neuronal fate determinant MEIS2.
Diese Arbeit hatte das Ziel, die Größe einer DVT-Aufnahme (FOV) mit der Größe der durch die Indikationsstellung definierten Region (ROI) zu vergleichen. Durch eine speziell dafür entwickelte Software sollten Messungen in den Datensätzen ermöglicht werden. Die dazu verwendeten 332 Datensätze wurden zufallsverteilt aus den mit einem Orthophos SL-3D DVT-Gerät der Firma Dentsply Sirona in der Poliklinik für zahnärztliche Chirurgie und Implantologie des ZZMK (Carolinum) in Frankfurt angefertigten Röntgenaufnahmen selektiert.
Es wurde die Auswertungssoftware ExRoi entwickelt, mit der die Werte des axialen Durchmessers, die Höhe (vertikale Dimension) sowie die Distanz der Mittelpunkte von FOV und ROI direkt in den Datensätzen bestimmt werden konnten. Zusätzlich wurde festgehalten, welche rechtfertigenden Indikationen gestellt und welche Auflösungsmodi verwendet wurden.
Die Stichprobe bestand aus Aufnahmen mit einem axialen Durchmesser von 8 cm [VOL 1] (n= 76, entsprechend 46,39%), 5 cm Durchmesser [VOL 2] (n = 102, entsprechend 30,72%) und 11 cm Durchmesser [VOL 3] (n= 154, entsprechend 22,89%). 95,18% der Aufnahmen wurden im HD-Modus mit laut Herstellerangaben vier Mal so vielen Aufnahmen im Vergleich zum SD-Modus angefertigt. Hauptindikationen waren Implantat Planung (45,1%) und Planungen komplizierter Zahn-Extraktionen (25,5%).
Die Messungen zum Vergleich des axialen Durchmessers zeigten, dass bei Verwendung des VOL 2 die ROI im Mittel den größten Anteil der FOV nutzt (78,52 %), den kleinsten Anteil nutzt durchschnittlich VOL 1 (56,04 %). Dazwischen liegt VOL 3 (69,12 %). In der Vertikalen nutzt die ROI von VOL 3 mittelwertig den größten Anteil der FOV (81,87 %), den kleinsten Mittelwert hat VOL 1 (58,76 %). VOL 2 liegt zwischen diesen Werten (64,47 %).
In allen Fällen war das FOV größer als die ROI und die ROI lag im Bereich des gewählten FOV.
Die Mittelpunkte von FOV und ROI lagen im Mittel in der axialen Ebene in Abhängigkeit vom gewählten Volumen um rund 9-13 mm auseinander, in der coronalen und sagittalen Ebene um rund 5-6mm.
Aus diesen Ergebnissen kann für das verwendete Gerät eine gute Trefferquote für die ROI abgeleitet werden. Höhe und Durchmesser des FOV hätten in den meisten Fällen kleiner gewählt werden können, liegen aber angesichts der vorhandenen Auswahl-Optionen des Röntgengeräts zur Dimensionierung der Volumina in einem akzeptablen Bereich.
Highlights
• Artificial intelligence systems for mechanically ventilated patients are increasing.
• The clinical and financial impact of these models are often unexamined.
• We developed a generic health-economic model for artificial intelligence systems.
• This model assesses the cost-effectiveness for many different scenarios.
• The developed framework is easily adjustable to other (clinical) situations.
Abstract
Purpose: The health and economic consequences of artificial intelligence (AI) systems for mechanically ventilated intensive care unit patients often remain unstudied. Early health technology assessments (HTA) can examine the potential impact of AI systems by using available data and simulations. Therefore, we developed a generic health-economic model suitable for early HTA of AI systems for mechanically ventilated patients.
Materials and methods: Our generic health-economic model simulates mechanically ventilated patients from their hospitalisation until their death. The model simulates two scenarios, care as usual and care with the AI system, and compares these scenarios to estimate their cost-effectiveness.
Results: The generic health-economic model we developed is suitable for estimating the cost-effectiveness of various AI systems. By varying input parameters and assumptions, the model can examine the cost-effectiveness of AI systems across a wide range of different clinical settings.
Conclusions: Using the proposed generic health-economic model, investors and innovators can easily assess whether implementing a certain AI system is likely to be cost-effective before an exact clinical impact is determined. The results of the early HTA can aid investors and innovators in deployment of AI systems by supporting development decisions, informing value-based pricing, clinical trial design, and selection of target patient groups.
Highlights
• Deletion of SPPL3 promotes resistance of malignant B cells to NK cell cytotoxicity
• Loss of SPPL3 blocks ligand binding to NK receptors via increased N-glycosylation
• B3GNT2 deletion reduces LacNAc addition and restores SPPL3-KO cell sensitivity to NK cells
• SPPL3-deficient cells are enriched in tetra-antennary N-glycans with LacNAc elongations
Summary
Natural killer (NK) cells are primary defenders against cancer precursors, but cancer cells can persist by evading immune surveillance. To investigate the genetic mechanisms underlying this evasion, we perform a genome-wide CRISPR screen using B lymphoblastoid cells. SPPL3, a peptidase that cleaves glycosyltransferases in the Golgi, emerges as a top hit facilitating evasion from NK cytotoxicity. SPPL3-deleted cells accumulate glycosyltransferases and complex N-glycans, disrupting not only binding of ligands to NK receptors but also binding of rituximab, a CD20 antibody approved for treating B cell cancers. Notably, inhibiting N-glycan maturation restores receptor binding and sensitivity to NK cells. A secondary CRISPR screen in SPPL3-deficient cells identifies B3GNT2, a transferase-mediating poly-LacNAc extension, as crucial for resistance. Mass spectrometry confirms enrichment of N-glycans bearing poly-LacNAc upon SPPL3 loss. Collectively, our study shows the essential role of SPPL3 and poly-LacNAc in cancer immune evasion, suggesting a promising target for cancer treatment.
Inflammation is a regulated reaction of the body to control a threat such as infection or injury. An efficient resolution of inflammation is critical to prevent the development of chronic inflammation and to restore tissue homeostasis. Macrophages (Mf) play a crucial role in the onset, but also in the resolution of inflammation, because they phagocytose and eliminate pathogens and tissue debris. Efficient efferocytosis, i.e. the engulfment of apoptotic cells, represents an important trigger for the onset of the resolution response and contributes to the pro-resolving reprogramming of Mf. Despite the importance of post- transcriptional modes of regulation during the resolution phase and translational control as a key node modulating gene expression in immune cells, relevant translational alterations remain largely elusive.
In the present study, I aimed to identify translationally regulated targets in inflammatory primary murine Mf upon resolution-promoting efferocytosis. To this end, I used total RNA-sequencing as well as de novo proteomics analyses to determine global transcriptional and translational changes. Sequencing data confirmed that efferocytosis induced a pro-resolution signature in inflammatory Mf and pointed towards translational regulation because the related integrated stress response was enriched upon efferocytosis. While changes of gene expression between efferocytic and non-efferocytic Mf appeared rather small at the transcriptional level, I observed considerable differences at the level of de novo synthesized proteins. This finding suggests a regulation at the level of translation. Furthermore, the tight connection between translational and metabolic changes was confirmed by enriched metabolism-associated terms of targets upregulated by efferocytosis at both RNA and de novo protein level. Interestingly, analysis of translationally regulated targets in response to inflammatory stimulation showed reduced translation for most targets, with only little impact of efferocytosis. Among those targets, I identified pro-resolving matrix metallopeptidase 12 (Mmp12) as a novel candidate, which showed translational repression during early inflammation and translational increase during the resolution phase. Noteworthy, a first indicator for a potential translation regulatory component of Mmp12 were the extremely high mRNA levels and not overly high de novo protein levels. Validation experiments recapitulated a slight elevation of Mmp12 mRNA expression and a significant downregulation of MMP12 intracellular protein levels in inflammatory Mf, as observed in the RNA-seq and de novo proteomics datasets. To investigate whether the discrepancy in mRNA and protein expression were due to changes in translation, I applied polysomal fractionation analysis to determine the translational status of Mmp12. Inflammatory Mf displayed a significantly lower relative Mmp12 mRNA abundance in the late polysomes compared to naïve Mf, suggesting reduced translational efficiency upon inflammatory stimulation. Consequently, extracellular MMP12 levels in the supernatant of inflammatory Mf decreased, although with a slight delay.
The functional impact of attenuated Mmp12 translation upon inflammatory stimulation was assessed in migration assays. While siRNA-mediated knockdown of Mmp12 did not alter Mf migration on uncoated plates, it increased migration 3-fold on matrigel/elastin-coated plates. Importantly, the increase in migrated distance driven by siMmp12 could be lowered by the addition of exogenous recombinant MMP12 protein. In line with reduced Mmp12 translation and MMP12 protein in inflammatory Mf, I observed a significant increase in cell migration on matrigel/elastin-coated plates, while it remained unaltered on uncoated plates. Consequently, Mf elastase MMP12 degrades elastin, thereby cell migration along elastin fibers is diminished. In inflammatory Mf, Mmp12 is translationally downregulated, thereby enhancing the migratory capacity.
In summary, the present study identifies a substantial contribution of translational regulation in the course of inflammation shown by high changes between inflammatory naïve and efferocytic Mf at the de novo proteomic level. Specifically, I was able to determine the translational regulation of pro-resolving Mmp12, which is repressed during early inflammation and recovers during the resolution phase. Functionally, translational control of MMP12 emerged as a strategy to alter the migratory properties of Mf, enabling enhanced, matrix- dependent migration of Mf during the early inflammatory phase, while restricting migration during the resolution phase.
Non-alcoholic steatohepatitis (NASH) and alcoholic steatohepatitis (ASH) are the leading causes of liver disease worldwide. To identify disease-specific pathomechanisms, we analyzed the lipidome, metabolome and immune cell recruitment in livers in both diseases. Mice harboring ASH or NASH had comparable disease severities regarding mortality rate, neurological behavior, expression of fibrosis marker and albumin levels. Lipid droplet size was higher in NASH than ASH and qualitative differences in the lipidome were mainly based on incorporation of diet-specific fatty acids into triglycerides, phosphatidylcholines and lysophosphatidylcholines. Metabolomic analysis showed downregulated nucleoside levels in both models. Here, the corresponding uremic metabolites were only upregulated in NASH suggesting stronger cellular senescence, which was supported by lower antioxidant levels in NASH as compared to ASH. While altered urea cycle metabolites suggest increased nitric oxide synthesis in both models, in ASH, this depended on increased L-homoarginine levels indicating a cardiovascular response mechanism. Interestingly, only in NASH were the levels of tryptophan and its anti-inflammatory metabolite kynurenine upregulated. Fittingly, high-content immunohistochemistry showed a decreased macrophage recruitment and an increased polarization towards M2-like macrophages in NASH. In conclusion, with comparable disease severity in both models, higher lipid storage, oxidative stress and tryptophan/kynurenine levels were seen in NASH, leading to distinct immune responses.
In a recent discussion on how to deal with data analysis issues initiated by reviewers of pain-related scientific manuscripts in the European Journal of Pain, a seemingly simple statistical issue was raised: two subsets of data in a paper had the same mean and standard deviation. A reviewer asked for a statistical test for or against the identity of the subset distributions. The authors insisted that if the mean and standard deviation were the same, this was sufficient evidence that the subsets of data were not significantly different.
This prompted a discussion among pain researchers, who are not necessarily primarily from the field of data science, a discussion of the importance of carefully examining the distribution of pain-related data in a journal whose primary audience is pain researchers seems warranted...
Objectives In this early retrospective cohort study, a total of 26 patients with SARS-CoV-2 were treated with bamlanivimab or casirivimab/imdevimab, and the reduction of the viral load associated with the developed clinical symptoms was analyzed.
Methods: Patients in the intervention groups received bamlanivimab or casirivimab/imdevimab. Patients without treatment served as control. Outcomes were assessed by clinical symptoms and change in log viral load from baseline based on the cycle threshold over a period of 18 days.
Results: Median log viral load decline was higher in both intervention groups after 3 and 6 days compared to control. However, at later time points, the decline of the viral load was more distinct in the control group. Mild symptoms of COVID-19 were observed in 6.3% of the intervention groups and in no patient of the control. No patients treated with bamlanivimab, 18.8% treated with casirivimab/imdevimab, and 14.2% in the control group developed moderate symptoms. Severe symptoms were recorded only in the control group (14.2%), including one related death.
Conclusion: Treatment with monoclonal SARS-CoV-2 antibodies seems to accelerate decline of virus loads, especially in the first 6 days after administration, compared to control. This may be associated with a reduced likeliness of a severe course of COVID-19.
Das Glioblastom ist eine tödliche maligne Erkrankung des zentralen Nervensystems. Etablierte Therapiekonzepte resultieren in einer Fünfjahresüberlebensrate von fünf Prozent. Die derart infauste Prognose wird unter anderem bedingt durch die Heterogenität des Tumors. Insbesondere einer Population stammzellartiger Zellen wird die Verantwortung für Resistenz und Rekurrenz des Glioblastoms zugesprochen. Die genuine Plastizität des Glioblastoms mit entsprechender Fähigkeit zur Änderungen tumorweiter Expressionsprofile und Ausbildung einzigartiger funktioneller Fähigkeiten kann ohne gezielte Beeinträchtigung von stammzellartigen Zellen womöglich nicht ausreichend überwunden werden. Als Urheber kritischer Eigenschaften erscheint die erfolgreiche Elimination dieser Population innerhalb des Glioblastoms notwendig um nachhaltige Therapieerfolge zu erzielen. Mögliche Strategien der Elimination stammzellartiger Zellen setzen an Differenzierung und Ausbeutung stammzelltypischer Signalwege zur Modulation dieser Zellen an. Hierdurch sollen zentrale Fähigkeiten der Population stammzellartiger Zellen, wie Selbsterneuerung, Resistenz gegenüber Strahlen- und Chemotherapie und erneute Formation heterogener Tumore, überwunden werden.
Zentrale zelluläre Prozesse, welche zum Erhalt des stammzellartigen Zustandes dieser Zellen beitragen, sind unter anderem der Hedgehog- und Notch-Signalweg. Einer Beeinträchtigung dieser Signalwege wohnt womöglich die Fähigkeit der effektiven Modulation zentraler Eigenschaften stammzellartiger Zellen inne. Neben diesen Signalwegen gibt es eine Reihe weiterer Prozesse, welchen eine Urheberschaft an der Resistenz der Zellen zugesprochen wird. Hierzu zählt beispielweise der Prozess der Autophagie. Die Autophagie ist ein hochkonservierter zellulärer Mechanismus zur Selbsterneuerung durch Selbstdegradation fehlerhafter zellulärer Komponenten. Gleichzeitig kann die Autophagie durch eine Überaktivität zu einem spezifischen, autophagischen Zelltod beitragen. Die Modulation dieses Dualismus kann in einer Vielzahl von Tumoren, so auch im Glioblastom, das Schicksal einer tumorfördernden Autophagie in eine antitumorale Autophagie ändern.
Im Rahmen dieser Arbeit wurde erstmalig eine Modulation zentraler Eigenschaften stammzellartiger Zellen durch die Beeinflussung ihrer zellulären Prozesse mittels kombinierter Therapie durch Arsentrioxid oder GANT und (-)-Gossypol gezeigt. Arsentrioxid wirkt unspezifisch unter anderem als Inhibitor von Notch- und Hedgehog-Signalweg. Diese Inhibition wurde auch in den untersuchten Zellen nachgewiesen und führte zu einer Reduktion von stammzelltypischen Markerproteinen und Fähigkeiten der Tumorgenese in -vitro und ex -vivo, sowie zur Sensitivierung gegenüber strahleninduzierten Schäden. Gegenüber einer spezifischen Hedgehog-Inhibition durch eine GANT-vermittelte Bindung an Gli-Transkriptionsfaktoren zeigten sich deutliche Vorteile der dualen Inhibition durch Arsentrioxid hinsichtlich der genannten Eigenschaften. Die Kombination der Substanzen mit dem pan-Bcl-Inhibitor (-)-Gossypol führte zu einer synergistischen Steigerung der antitumoralen Effekte. (-)-Gossypol wird in Gliomzellen insbesondere mit der Modulation der autophagischen Maschinerie und Auslösung eines autophagischen Zelltodes in Verbindung gebracht. Die Ergebnisse weisen parallele Signalweginteraktionen mit effektiver Modulation des DNA-Damage-Response-Systems durch die Reduktion des Proteins CHEK als kausalen Mechanismus des Synergismus der Substanzen aus.
Die beobachteten Änderungen der typischen Eigenschaften stammzellartiger Zellen durch die Therapie mit Arsentrioxid und (-)-Gossypol implizieren lohnende Folgeuntersuchungen zur weiteren Evaluation dieser Effekte in -vivo, um zukünftig translationale Ableitungen zu erlauben. Die Heterogenität des Glioblastoms und seine genuine Plastizität lassen sich womöglich erfolgreich durch multiple Eingriffe in unterschiedliche zelluläre Prozesse, hierunter Notch- und Hedgehog-Signaling, modulieren. Hierdurch könnten zentrale Eigenschaften des Glioblastoms eventuell effektiv verändert und Resistenz sowie Rekurrenz überwunden werden.
Oral e-Poster Presentations - Booth 1: Vascular 3, September 27, 2023, 10:00 AM - 10:40 AM
Background: Despite current clinical guidelines recommending suboccipital decompressive craniectomy (SDC) in patients with space-occupying cerebellar infarction when neurological deterioration occurs, the precise definition of such deterioration remains unclear. The current study aimed at characterizing whether clinical outcomes can be predicted by the GCS score immediately prior to SDC, and whether higher GCS scores are associated with better clinical outcomes. We aimed to characterize whether clinical outcomes can be predicted by the GCS score immediately prior to SDC, and if higher GCS scores are associated with better clinical outcomes.
Methods: In a single-center, retrospective analysis of 51 patients treated with SDC for space-occupying cerebellar infarction clinical and imaging data were evaluated at the timepoints of symptom onset, hospital admission and preoperatively. Clinical outcome was measured by mRS at the last available follow-up. Preoperative GCS scores were stratified into three groups (GCS 3-8, 9-11 and 12-15). Univariate and multivariate Cox regression analyses were performed using clinical and radiological parameters as predictors of clinical outcome.
Results: In Cox-regression analysis using mRS of 1-2 as a positive clinical outcome we found a significant increase in the proportional hazard ratio (HR) of 6.581 [CI 1.839-36.414]; p=0.031 for GCS scores of 12-15 prior to SDC. Clinical outcomes (mRS 3-6) were associated with infarct volume above 6.0 cm3 (HR 2.473 [CI 1.209-5.057]; p=0.013), tonsillar herniation (HR: 0.279 [CI 0.083-0.933]; p=0.038), brainstem compression (HR 0.304 [CI 0.123-0.749]; p=0.010) and a preoperative GCS score of 3-8 (HR 2.386 [CI 1.160-4.906]; p=0.018).
Conclusions: SDC should be considered in patients with infarct volumes above 6.0 cm3 with GCS scores higher than previously described in the literature, as these patients may show better long-term outcome than those in which surgery is delayed until a GCS score of 11 or lower.
Einleitung: Das Pseudoaneurysma (PSA) stellt eine der häufigsten Komplikationen nach arteriellen Punktionen dar. Dabei unterscheiden sich die Komplikationsraten kathetergestützter Verfahren bei diagnostischen Eingriffen deutlich von jenen bei therapeutischen Eingriffen. Zur Behandlung des Pseudoaneurysmas steht eine große Bandbreite an Therapieoptionen zur Verfügung, unter anderem die ultraschallgestützte Thrombininjektion (TI) sowie die Therapie mittels konventionellem Druckverband (DV). Jedoch werden venöse Thrombosen nach der Behandlung des Pseudoaneurysmas beschrieben. Der Einfluss von Antikoagulantien (AK) und Thrombozytenaggregationshemmern (TAH) sowohl auf die Erfolgsraten der Pseudoaneurysmatherapie als auch die anschließende Entstehung venöser Thrombosen wurde bisher noch nicht analysiert.
Fragestellung: Die Effektivität des Druckverbands und der Thrombininjektion bei Patienten mit Pseudoaneurysma und damit assoziierten venösen Thrombosen wurde geprüft. Außerdem wurden die Auswirkungen von Antikoagulantien und Thrombozytenaggregationshemmern auf die Erfolgsraten der Pseudoaneurysmatherapie und die damit assoziierten venösen Thrombosen untersucht.
Methoden: Es wurden von Januar 2010 bis Dezember 2018 insgesamt 468 Patienten mit Pseudoaneurysma untersucht, wovon 238 Patienten in die retrospektive Studie eingeschlossen wurden. Die Behandlung des Pseudoaneurysmas erfolgte mittels Thrombininjektion oder Druckverband. Nach Ablauf von 24 Stunden wurde der Therapieerfolg sonographisch kontrolliert, wobei auch auf das Neuauftreten venöser Beinvenenthrombosen geachtet wurde. Bei allen Patienten wurde die Medikation mit Antikoagulantien und Thrombozytenaggregationshemmern zum Zeitpunkt der Pseudoaneurysmatherapie erhoben.
Ergebnisse: Die Thrombininjektion war dem Druckverband sowohl hinsichtlich des größeren Therapieerfolgs (TI 86% vs. DV 52%, p<0,001) als auch der geringeren Thromboseinzidenz (TI 7,7% vs. DV 21,3%, p=0,039) signifikant überlegen.
Insgesamt erlitten 40 der 238 Patienten eine neu aufgetretene venöse Thrombose der unteren Extremität. Auch bei Betrachtung des Einflusses von Antikoagulantien und Thrombozytenaggregationshemmern erwies sich die 5 Thrombininjektion als dem Druckverband signifikant überlegen. Jedoch wurde bei der Thrombininjektion eine um 18% niedrigere Erfolgsrate unter Antikoagulation festgestellt (TIoAK 97% vs. TImAK 79%, p=0,22), wohingegen bei Druckverbandanlage unter Antikoagulation die Erfolgsrate nur um 6% geringer war (DVoAK 57% vs. DVmAK 51%, p=0,38). In Bezug auf die Thromboseraten nach Thrombininjektion bzw. Druckverband unter Antikoagulation oder Thrombozytenaggregationshemmern konnten keine signifikanten Unterschiede beobachtet werden.
Fazit: Es konnte nachgewiesen werden, dass die Thrombininjektion eine sichere Methode zur Behandlung des Pseudoaneurysmas darstellt und nach Ansicht der Autoren, bei vorhandener Expertise, primär angewandt werden sollte.
Denn die Thrombininjektion ist dem Druckverband in Bezug auf Erfolgs- und Thromboseraten signifikant überlegen. Antikoagulantien beeinträchtigen den Erfolg der Thrombininjektion stärker als den des Druckverbands, weshalb bei Notwendigkeit einer Pseudoaneurysmatherapie die Pausierung der Antikoagulantien im Rahmen einer patientenspezifischen Risiko-Nutzen-Abwägung in Betracht gezogen werden sollte.