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Long-range angular correlations on the near and away side in p–Pb collisions at √sNN=5.02 TeV
(2013)
Abelev, Betty ; Adam, Jaroslav ; Adamová, Dagmar ; Marshall Adare, Andrew ; Aggarwal, Madan Mohan ; Aglieri Rinella, Gianluca ; Agnello, Michelangelo ; Gabor Agocs, Andras ; Agostinelli, Andrea ; Ahammed, Zubayer ; Ahmad, Nazeer ; Ahmad, Arshad ; Ahn, Sul-Ah ; Ahn, Sang Un ; Ajaz, Muhammad ; Akindinov, Alexander ; Aleksandrov, Dmitry ; Alessandro, Bruno ; Alici, Andrea ; Alkin, Anton ; Jonathan Almaraz Avina, Erick ; Alme, Johan ; Alt, Torsten ; Altini, Valerio ; Altinpinar, Sedat ; Altsybeev, Igor ; Andrei, Cristian ; Andronic, Anton ; Anguelov, Venelin ; Anielski, Jonas ; Daniel Anson, Christopher ; Antičić, Tome ; Antinori, Federico ; Antonioli, Pietro ; Aphecetche, Laurent Bernard ; Appelshäuser, Harald ; Arbor, Nicolas ; Arcelli, Silvia ; Arend, Andreas ; Armesto, Nestor ; Arnaldi, Roberta ; Robert Aronsson, Tomas ; Arsene, Ionut Cristian ; Arslandok, Mesut ; Asryan, Andzhey ; Augustinus, Andre ; Averbeck, Ralf Peter ; Awes, Terry ; Heikki Aysto, Juha ; Danish Azmi, Mohd ; Jakob Bach, Matthias ; Badalà, Angela ; Baek, Yong Wook ; Bailhache, Raphaëlle ; Bala, Renu ; Baldini Ferroli, Rinaldo ; Baldisseri, Alberto ; Baltasar Dos Santos Pedrosa, Fernando ; Ban, Jaroslav ; Chandra Baral, Rama ; Barbera, Roberto ; Barile, Francesco ; Barnaföldi, Gergely Gábor ; Stuart Barnby, Lee ; Barret, Valerie ; Gustaw Bartke, Jerzy ; Basile, Maurizio ; Bastid, Nicole ; Basu, Sumit ; Bathen, Bastian ; Batigne, Guillaume ; Batyunya, Boris ; Heinrich Baumann, Christoph ; Gardner Bearden, Ian ; Beck, Hans ; Kumar Behera, Nirbhay ; Belikov, Iouri ; Bellini, Francesca ; Bellwied, Rene ; Belmont-Moreno, Ernesto ; Bencédi, Gyula ; Beolè, Stefania ; Berceanu, Ionela ; Bercuci, Alexandru ; Berdnikov, Yaroslav ; Berényi, Dániel ; Annick Erica Bergognon, Anais ; Berzano, Dario ; Betev, Latchezar ; Bhasin, Anju ; Kumar Bhati, Ashok ; Bhom, Jihyun ; Bianchi, Livio ; Bianchi, Nicola ; Bielčík, Jaroslav ; Bielčíková, Jana ; Bilandzic, Ante ; Bjelogrlic, Sandro ; Blanco, Francesco ; Blanco, Fernando ; Blau, Dmitry S. ; Blume, Christoph ; Boccioli, Marco ; Boettger, Stefan ; Bogdanov, Alexey A. ; Bøggild, Hans ; Bogolyubsky, Mikhail ; Boldizsar, Laszlo ; Bombara, Marek ; Book, Julian ; Borel, Herve ; Borissov, Alexander ; Bossú, Francesco ; Botje, Michiel ; Botta, Elena ; Braidot, Ermes ; Braun-Munzinger, Peter ; Bregant, Marco ; Breitner, Timo Gunther ; Alexander Broker, Theo ; Allen Browning, Tyler ; Broz, Michal ; Brun, Rene ; Bruna, Elena ; Eugenio Bruno, Giuseppe ; Budnikov, Dmitry ; Büsching, Henner ; Bufalino, Stefania ; Bunčić, Predrag ; Busch, Oliver ; Buthelezi, Edith Zinhle ; Caballero Orduna, Diego ; Caffarri, Davide ; Cai, Xu ; Caines, Helen Louise ; Calvo Villar, Ernesto ; Camerini, Paolo ; Canoa Roman, Veronica ; Cara Romeo, Giovanni ; Carena, Wisla ; Carena, Francesco ; Carlin Filho, Nelson ; Carminati, Federico ; Ofelia Casanova Diaz, Amaya ; Castillo Castellanos, Javier Ernesto ; Castillo Hernández, Juan Francisco ; Anna Rita Casula, Ester ; Catanescu, Vasile ; Cavicchioli, Costanza ; Ceballos Sanchez, Cesar ; Čepila, Jan ; Cerello, Piergiaio ; Chang, Beomsu ; Chapeland, Sylvain ; Fernand Charvet, Jean-Luc ; Chattopadhyay, Sukalyan ; Chattopadhyay, Subhasis ; Chawla, Isha ; Gerard Cherney, Michael ; Cheshkov, Cvetan Valeriev ; Cheynis, Brigitte ; Miguel Chibante Barroso, Vasco ; Chinellato, David Dobrigkeit ; Chochula, Peter ; Chojnacki, Marek ; Choudhury, Subikash ; Christakoglou, Panagiotis ; Christensen, Christian Holm ; Christiansen, Peter L. ; Chujo, Tatsuya ; Chung, Suh-Urk ; Cicalò, Corrado ; Cifarelli, Luisa ; Cindolo, Federico ; Willy Andre Cleymans, Jean ; Coccetti, Fabrizio ; Colamaria, Fabio Filippo ; Colella, Domenico ; Collu, Alberto ; Conesa Balbastre, Gustavo ; Conesa del Valle, Zaida ; Elizabeth Connors, Megan ; Contin, Giacomo ; Contreras Nuno, Jesus Guillermo ; Cormier, Thomas Michael ; Corrales Morales, Yasser ; Cortese, Pietro ; Cortes Maldonado, Ismael ; Rogerio Cosentino, Mauro ; Costa, Filippo ; Enrique Cotallo, Manuel ; Crescio, Elisabetta ; Crochet, Philippe ; Cruz Alaniz, Emilia ; Cruz Albino, Rigoberto ; Cuautle, Eleazar ; Cunqueiro Mendez, Leticia ; Dainese, Andrea ; Dalsgaard, Hans Hjersing ; Danu, Andrea ; Das, Indranil ; Das, Debasish ; Das, Supriya ; Das, Kushal ; Kumar Dash, Ajay ; Dash, Sadhana ; De, Sudipan ; de Barros, Gabriel ; De Caro, Annalisa ; De Cataldo, Giacinto ; Cuveland, Jan de ; De Falco, Alessandro ; De Gruttola, Daniele ; Delagrange, Hugues ; Deloff, Andrzej ; De Marco, Nora ; Denes, Ervin ; De Pasquale, Salvatore ; Deppman, Airton ; DʼErasmo, Ginevra ; Stefan de Rooij, Raoul ; Angel Diaz Corchero, Miguel ; Di Bari, Domenico ; Dietel, Thomas ; Di Giglio, Carmelo ; Di Liberto, Sergio ; Di Mauro, Antonio ; Di Nezza, Pasquale ; Divià, Roberto ; Djuvsland, Øystein ; Florin Dobrin, Alexandru ; Antoni Dobrowolski, Tadeusz ; Donigus, Benjamin ; Dordic, Olja ; Driga, Olga ; Kumar Dubey, Anand ; Dubla, Andrea ; Ducroux, Laurent ; Dupieux, Pascal ; Dutta Majumdar, A.K. ; Elia, Domenico ; Philip Emschermann, David ; Engel, Heiko ; Erazmus, Barbara ; Austrheim Erdal, Hege ; Espagnon, Bruno ; Danielle Estienne, Magali ; Esumi, ShinIchi ; Evans, David ; Eyyubova, Gyulnara ; Fabris, Daniela ; Faivre, Julien ; Falchieri, Davide ; Fantoni, Alessandra ; Fasel, Markus ; Worsley Fearick, Roger ; Fehlker, Dominik ; Feldkamp, Linus ; Felea, Daniel ; Feliciello, Alessandro ; Fenton-Olsen, Bo ; Feofilov, Grigory ; Fernández Téllez, Arturo ; Ferretti, Alessandro ; Festanti, Andrea ; Figiel, Jan ; Figueredo, Marcel ; Filchagin, Sergey ; Finogeev, Dmitry ; Fionda, Fiorella Maria Celeste ; Enrichetta, Maria Fiore ; Floratos, Emmanuel ; Floris, Michele ; Foertsch, Siegfried Valentin ; Foka, Panagiota ; Fokin, Sergey ; Fragiacomo, Enrico ; Francescon, Andrea ; Michael Frankenfeld, Ulrich ; Fuchs, Ulrich ; Furget, Christophe ; Fusco Girard, Mario ; Gaardhøje, Jens Jørgen ; Gagliardi, Martino ; Gago Medina, Alberto Martín ; Gallio, Mauro ; Gangadharan, Dhevan Raja ; Ganoti, Paraskevi ; Garabatos Cuadrado, Jose Maria ; Garcia-Solis, Edmundo ; Garishvili, Irakli ; Gerhard, Jochen ; Germain, Marie ; Geuna, Claudio ; Gheata, Mihaela ; Gheata, Andrei George ; Ghidini, Bruno ; Ghosh, Premomoy ; Gianotti, Paola ; Robert Girard, Martin ; Giubellino, Paolo ; Gładysz-Dziaduś, Ewa ; Glässel, Peter ; Gomez, Ramon ; Gonzalez Ferreiro, Elena ; Helena Gonzalez-Trueba, Laura ; González Zamora, Pedro ; Gorbunov, Sergey ; Goswami, Ankita ; Gotovac, Sven ; Graczykowski, Łukasz Kamil ; Grajcarek, Robert ; Grelli, Alessandro ; Grigoraș, Costin ; Gabriela Grigoras, Alina ; Grigoriev, Vladislav A. ; Grigoryan, Ara ; Grigoryan, Smbat ; Grinyov, Boris ; Grion, Nevio ; Gros, Philippe ; Große-Oetringhaus, Jan Fiete ; Grossiord, Jean-Yves ; Grosso, Raffaele ; Guber, Fedor ; Guernane, Rachid ; Guerzoni, Barbara ; Rene Joseph Guilbaud, Maxime ; Herlache Gulbrandsen, Kristjan ; Gulkanyan, Hrant ; Gunji, Taku ; Gupta, Anik ; Gupta, Ramni ; Haake, Rüdiger ; Senneset Haaland, Oystein ; Marie Hadjidakis, Cynthia ; Haiduc, Maria ; Hamagaki, Hideki ; Hamar, Gergö ; Han, Byounghee ; David Hanratty, Luke ; Hansen, Alexander ; Harmanova, Zuzana ; William Harris, John ; Hartig, Matthias ; Harton, Austin ; Hatzifotiadou, Despoina ; Hayashi, Shinichi ; Hayrapetyan, Arsen ; Heckel, Stefan Thomas ; Ansgar Heide, Markus ; Helstrup, Håvard ; Ionut Herghelegiu, Andrei ; Antonio Herrera Corral, Gerardo ; Herrmann, Norbert ; Hess, Benjamin Andreas ; Hetland, Kristin Fanebust ; Hicks, Bernard ; Hippolyte, Boris ; Hori, Yasuto ; Zahariev Hristov, Peter ; Hrivnacova, Ivana ; Huang, Meidana ; Humanic, Thomas J. ; Sung Hwang, Dae ; Ichou, Raphaelle ; Ilkaev, Radiy ; Ilkiv, Iryna ; Inaba, Motoi ; Incani, Elisa ; Giaio Innocenti, Pier ; Michele Innocenti, Gian ; Ippolitov, Mikhail ; Irfan, Muhammad ; Geae Ivan, Cristian ; Ivanov, Vladimir ; Ivanov, Andrey ; Ivanov, Marian ; Ivanytskyi, Oleksii ; Wlodzimierz Jacholkowski, Adam ; Jacobs, Peter ; Jin Jang, Haeng ; Anna Janik, Malgorzata ; Janik, Rudolf ; Jayarathna, Sandun ; Jena, Satyajit ; Manu Jha, Deeptanshu ; Tonatiuh Jimenez Bustamante, Raul ; Graham Jones, Peter ; Taik Jung, Hyung ; Jusko, Anton ; Kaidalov, Alexei ; Kalcher, Sebastian ; Kalinak, Peter ; Esa Aukusti Kalliokoski, Tuomo ; Kalweit, Alexander Philipp ; Hwan Kang, Ju ; Kaplin, Vladimir ; Karasu Uysal, Ayben ; Karavichev, Oleg V. ; Karavicheva, Tatiana L. ; Karpechev, Evgeny ; Kazantsev, Andrey ; Kebschull, Udo ; Keidel, Ralf ; Khan, Palash ; Ahmad Khan, Shuaib ; Mohammed Khan, Mohisin ; Hussain Khan, Kamal ; Khanzadeev, Alexei ; Kharlov, Yury ; Kileng, Bjarte ; Kim, Beomkyu ; Sook Kim, Jin ; Kim, Jonghyun ; Jo Kim, Dong ; Won Kim, Do ; Kim, Taesoo ; Yong Kim, Se ; Kim, Mimae ; Kim, Minwoo ; Kirsch, Stefan ; Kisel, Ivan ; Kiselev, Sergej N. ; Ryszard Kisiel, Adam ; Lynn Klay, Jennifer ; Klein, Jochen ; Klein-Bösing, Christian ; Kliemant, Michael ; Kluge, Alexander ; Linus Knichel, Michael ; Garritt Knospe, Anders ; Kohler, Markus ; Kollegger, Thorsten ; Kolojvari, Anatoly ; Kompaniets, Mikhail ; Kondratiev, Valery ; Kondratyeva, Natalia ; Konevskih, Artem ; Kovalenko, Vladimir ; Kowalski, Marek ; Kox, Serge ; Koyithatta Meethaleveedu, Greeshma ; Kral, Jiří ; Králik, Ivan ; Kramer, Frederick ; Kravčáková, Adela ; Krawutschke, Tobias ; Křelina, Michal ; Kretz, Matthias ; Krivda, Marian ; Krizek, Filip ; Krus, Miroslav ; Kryshen, Evgeny ; Krzewicki, Mikolaj ; Kucheriaev, Yury ; Kugathasan, Thanushan ; Claude Kuhn, Christian ; Kuijer, Paul ; Kulakov, Igor ; Kumar, Jitendra ; Kurashvili, Podist ; Kurepin, Alexander ; Kurepin, Alexey B. ; Kuryakin, Alexey ; Kushpil, Svetlana ; Kushpil, Vasily ; Kvaerno, Henning ; Jung Kweon, Min ; Kwon, Youngil ; Ladron de Guevara, Pedro ; Lakomov, Igor ; Langoy, Rune ; Louise La Pointe, Sarah ; Ernesto Lara, Camilo ; Xavier Lardeux, Antoine ; La Rocca, Paola ; Lea, Ramona ; Lechman, Mateusz ; Sang Lee, Ki ; Chul Lee, Sung ; Richard Lee, Graham ; Legrand, Iosif ; Walter Lehnert, Joerg ; Laurent Lenhardt, Matthieu ; Lenti, Vito ; Leon, Hermes ; Leon Monzon, Ildefonso ; Leon Vargas, Hermes ; Lévai, Peter ; Li, Shuang ; Lien, Jaen ; Lietava, Roman ; Lindal, Svein ; Lindenstruth, Volker ; Lippmann, Christian ; Annan Lisa, Michael ; Martin Ljunggren, Hans ; Loenne, Per-Ivar ; Loggins, Vera ; Loginov, Vitaly ; Lohner, Daniel ; Loizides, Constantinos ; Krister Loo, Kai ; Bernard Lopez, Xavier ; López Torres, Ernesto ; Lovhoiden, Gunnar ; Lu, Xianguo ; Luettig, Philipp ; Lunardon, Marcello ; Luo, Jiebin ; Luparello, Grazia ; Luzzi, Cinzia ; Ma, Rongrong ; Ma, Ke ; Minthaka Madagodahettige-Don, Dilan ; Maevskaya, Alla ; Mager, Magnus ; Mahapatra, Durga Prasad ; Maire, Antonin ; Malaev, Mikhail ; Alicia Maldonado Cervantes, Ivonne ; Malinina, Liudmila ; MalʼKevich, Dmitry ; Malzacher, Peter ; Mamonov, Alexander ; Henri Antoine Manceau, Loic ; Kumar Mangotra, Lalit ; Manko, Vladislav ; Manso, Franck ; Manzari, Vito ; Mao, Yaxian ; Marchisone, Massimiliano ; Mareš, Jiří ; Margagliotti, Giacomo Vito ; Margotti, Anselmo ; Maria Marin, Ana ; Markert, Christina ; Marquard, Marco ; Martashvili, Irakli ; Alice Martin, Nicole ; Martinengo, Paolo ; Ivan Martinez, Mario Ivan ; Martinez Davalos, Arnulfo ; Martínez Garcia, Ginés ; Martynov, Yevgen ; Jean-Michel Mas, Alexis ; Masciocchi, Silvia ; Masera, Massimo ; Masoni, Alberto ; Marie Massacrier, Laure ; Mastroserio, Annalisa ; Tomasz Matyja, Adam ; Mayer, Christoph ; Mazer, Joel ; Maria Mazzoni, Alessandra ; Meddi, Franco ; Alejandro Menchaca-Rocha, Arturo ; Mercado Perez, Jae ; Meres, Michal ; Miake, Yasuo ; Milano, Leonardo ; Milošević, Jovan ; Mischke, André ; Nath Mishra, Aditya ; Miśkowiec, Dariusz Czesław ; Mihai Mitu, Ciprian ; Mizuno, Sanshiro ; Mlynarz, Jocelyn ; Mohanty, Bedangadas ; Molnar, Levente ; Manuel Montano Zetina, Luis ; Monteno, Marco ; Montes Prado, Esther ; Moon, Taebong ; Morando, Maurizio ; Aparecida Moreira De Godoy, Denise ; Moretto, Sandra ; Morreale, Astrid ; Morsch, Andreas ; Muccifora, Valeria ; Mudnic, Eugen ; Muhuri, Sanjib ; Mukherjee, Maitreyee ; Muller, Hans ; Munhoz, Marcelo ; Murray, Sean ; Musa, Luciano ; Musinsky, Jan ; Musso, Alfredo ; Kumar Nandi, Basanta ; Nania, Rosario ; Nappi, Eugenio ; Nattrass, Christine ; Kumar Nayak, Tapan ; Nazarenko, Sergey ; Nedosekin, Alexander ; Nicassio, Maria ; Niculescu, Mihai ; Svane Nielsen, Bae ; Niida, Takafumi ; Nikolaev, Sergey ; Nikolic, Vedran ; Nikulin, Sergey ; Nikulin, Vladimir ; Steven Nilsen, Bjorn ; Stormo Nilsson, Mads ; Noferini, Francesco ; Nomokonov, Petr V. ; Nooren, Gerardus ; Novitzky, Norbert ; Nyanin, Alexander ; Nyatha, Anitha ; Nygaard, Casper ; Nystrand, Joakim Ingemar ; Ochirov, Alexander ; Oskar Oeschler, Helmut ; Oh, Saehanseul ; Kun Oh, Sun ; Oleniacz, Janusz ; Carlos Oliveira Da Silva, Antonio ; Oppedisano, Chiara ; Ortiz Velasquez, Antonio ; Nils Erik Oskarsson, Anders ; Krystian Ostrowski, Piotr ; Tomasz Otwinowski, Jacek ; Oyama, Ken ; Ozawa, Kyoichiro ; Chiara Pachmayer, Yvonne ; Pachr, Milos ; Padilla, Fatima ; Pagano, Paola ; Paic, Guy ; Painke, Florian ; Pajares Vales, Carlos ; Kumar Pal, Susanta ; Singh Palaha, Arvinder ; Palmeri, Armando ; Papikyan, Vardanush ; Pappalardo, Giuseppe Salvatore ; Jin Park, Woo ; Passfeld, Annika ; Pastircak, Blahoslav ; Ivanovich Patalakha, Dmitri ; Paticchio, Vincenzo ; Paul, Biswarup ; Pavlinov, Alexei ; Pawlak, Tomasz Jan ; Peitzmann, Thomas ; Denis Antonio Pereira Da Costa, Hugo ; Pereira De Oliveira Filho, Elienos ; Peresunko, Dmitri ; Eugenio Perez Lara, Carlos ; Perini, Diego ; Perrino, Davide ; Stanislaw Peryt, Wiktor ; Pesci, Alessandro ; Peskov, Vladimir ; Pestov, Yury N. ; Petráček, Vojtech ; Petran, Michal ; Petris, Mariana ; Rumenov Petrov, Plamen ; Petrovici, Mihai A. ; Petta, Catia ; Piano, Stefano ; Pikna, Miroslav ; Pillot, Philippe ; Pinazza, Ombretta ; Pinsky, Lawrence ; Pitz, Nora ; Piyarathna, Danthasinghe ; Planinic, Mirko ; Ploskon, Mateusz Andrzej ; Marian Pluta, Jan ; Pocheptsov, Timur ; Pochybova, Sona ; Luis Manuel Podesta Lerma, Pedro ; Poghosyan, Martin G. ; Polak, Karel ; Polichtchouk, Boris ; Pop, Amalia ; Porteboeuf-Houssais, Sarah Julie ; Pospisil, Vladimir ; Potukuchi, Baba ; Prasad, Sidharth Kumar ; Preghenella, Roberto ; Prino, Francesco ; Andre Pruneau, Claude ; Pshenichnov, Igor A. ; Puddu, Giovanna ; Punin, Valery ; Putis, Marian ; Putschke, Jörn H. ; Quercigh, Emanuele ; Qvigstad, Henrik ; Rachevski, Alexandre ; Rademakers, Alphonse ; Samuli Raiha, Tomi ; Rak, Jan ; Malala Rakotozafindrabe, Andry ; Ramello, Luciano ; Ramirez Reyes, Abdiel ; Raniwala, Rashmi ; Raniwala, Sudhir ; Sakari Rasanen, Sami ; Theodor Rascanu, Bogdan ; Rathee, Deepika ; Francis Read, Kenneth ; Real, Jean-Sébastien ; Redlich, Krzysztof ; Jan Reed, Rosi ; Ur Rehman, Attiq ; Reichelt, Patrick ; Reicher, Martijn ; Arno Ernst Renfordt, Rainer ; Rita Reolon, Anna ; Reshetin, Andrey ; Vincenz Rettig, Felix ; Revol, Jean-Pierre ; Johannes Reygers, Klaus ; Riccati, Lodovico ; Angelo Ricci, Renato ; Richert, Tuva ; Richter, Matthias ; Riedler, Petra ; Riegler, Werner ; Riggi, Francesco ; Rodrı́guez Cahuantzi, Mario ; Rodriguez Manso, Alis ; Roed, Ketil ; Rohr, David ; Röhrich, Dieter ; Romita, Rosa ; Ronchetti, Federico ; Rosnet, Philippe ; Rossegger, Stefan ; Rossi, Andrea ; Sophie Roy, Christelle ; Kumar Roy, Pradip ; Juan Rubio Montero, Antonio ; Rui, Rinaldo ; Russo, Riccardo ; Ryabinkin, Evgeny ; Rybicki, Andrzej ; Sadovskiy, Sergey ; Šafařík, Karel ; Sahoo, Raghunath ; Kumar Sahu, Pradip ; Saini, Jogender ; Sakaguchi, Hiroaki ; Sakai, Shingo ; Sakata, Dosatsu ; Albert Salgado, Carlos ; Salzwedel, Jai ; Singh Sambyal, Sanjeev ; Samsonov, Vladimir ; Sanchez Castro, Xitzel ; Šándor, Ladislav ; Sandoval, Andres ; Sano, Masato ; Santagati, Gianluca ; Santoro, Romualdo ; Jaako Sarkamo, Juho ; Scapparone, Eugenio ; Scarlassara, Fernando ; Paul Scharenberg, Rolf ; Schiaua, Claudiu Cornel ; Schicker, Rainer ; Joachim Schmidt, Christian ; Rudolf Schmidt, Hans ; Schuchmann, Simone ; Schukraft, Jürgen ; Schuster, Tim ; Roland Schutz, Yves ; Eberhard Schwarz, Kilian ; Schweda, Kai ; Scioli, Gilda ; Scomparin, Enrico ; Aaron Scott, Patrick ; Scott, Rebecca ; Segato, Gianfranco ; Selyuzhenkov, Ilya ; Senyukov, Serhiy ; Seo, Jeewon ; Serci, Sergio ; Serradilla, Eulogio ; Sevcenco, Adrian ; Shabetai, Alexandre ; Shabratova, Galina ; Shahoyan, Ruben ; Sharma, Natasha ; Sharma, Satish ; Sharma, Rohini ; Shigaki, Kenta ; Shtejer, Katherin ; Sibiriak, Yury ; Sicking, Eva ; Siddhanta, Sabyasachi ; Siemiarczuk, Teodor ; Olle Rickard Silvermyr, David ; Silvestre, Catherine ; Simatovic, Goran ; Simonetti, Giuseppe ; Narayana Singaraju, Rama ; Singh, Ranbir ; Singha, Subhash ; Singhal, Vikas ; Sinha, Bikash ; Sinha, Tinku ; Sitar, Branislav ; Sitta, Mario ; Skaali, Toralf Bernhard ; Skjerdal, Kyrre ; Smakal, Radek ; Smirnov, Nikolai ; Snellings, Raimond ; Sogaard, Carsten ; Ariel Soltz, Ron ; Son, Hyungsuk ; Song, Jihye ; Song, Myunggeun ; Soos, Csaba ; Soramel, Francesca ; Sputowska, Iwona ; Spyropoulou-Stassinaki, Martha ; Srivastava, Brijesh Kumar ; Stachel, Johanna ; Stan, Ionel ; Stefanek, Grzegorz ; Steinpreis, Matthew ; Anders Stenlund, Evert ; Francois Steyn, Gideon ; Hendrik Stiller, Johannes ; Stocco, Diego ; Stolpovskiy, Mikhail ; Strmen, Peter ; Suaide, Alexandre Alarcon do Passo ; Subieta Vasquez, Martin Alfonso ; Sugitate, Toru ; Suire, Christophe Pierre ; Sultanov, Rishat ; Šumbera, Michal ; Šuša, Tatjana ; Symons, Timothy ; Toledo, Alejandro Szanto de ; Szarka, Imrich ; Szczepankiewicz, Adam ; Krzysztof Szostak, Artur ; Szymanski, Maciej ; Takahashi, Jun ; Tapia Takaki, Jesus Daniel ; Tarantola Peloni, Attilio ; Tarazona Martinez, Alfonso ; Tauro, Arturo ; Tejeda Muñoz, Guillermo ; Telesca, Adriana ; Terrevoli, Cristina ; Mathias Thader, Jochen ; Thomas, Deepa ; Noel Tieulent, Raphael ; Timmins, Anthony Robert ; Tlusty, David ; Toia, Alberica ; Torii, Hisayuki ; Toscano, Luca ; Trubnikov, Victor ; Truesdale, David Christopher ; Trzaska, Wladyslaw Henryk ; Tsuji, Tomoya ; Tumkin, Alexandr ; Turrisi, Rosario ; Spedstad Tveter, Trine ; Glyndwr Ulery, Jason ; Ullaland, Kjetil ; Ulrich, Jochen ; Uras, Antonio ; Urban, Jozef ; Marie Urciuoli, Guido ; Usai, Gianluca ; Vajzer, Michal ; Vala, Martin ; Valencia Palomo, Lizardo ; Vallero, Sara ; Vyvre, Pierre vande ; Leeuwen, Marco van ; Vannucci, Luigi ; Diozcora Vargas, Aurora ; Varma, Raghava ; Vasileiou, Maria ; Vasiliev, Andrey ; Vechernin, Vladimir ; Veldhoen, Misha ; Venaruzzo, Massimo ; Vercellin, Ermanno ; Vergara, Sergio ; Vernet, Renaud ; Verweij, Marta ; Vicković, Linda ; Viesti, Giuseppe ; Viinikainen, Jussi ; Vilakazi, Zabulon ; Villalobos Baillie, Orlando ; Vinogradov, Yury I. ; Vinogradov, Alexander ; Vinogradov, Leonid ; Virgili, Tiziano ; Viyogi, Yogendra P. ; Vodopianov, Alexander ; Voloshin, Sergei ; Voloshin, Kirill ; Volpe, Giacomo ; Haller, Barthélémy von ; Vorobyev, Ivan ; Vranić, Danilo ; Vrláková, Janka ; Vulpescu, Bogdan ; Vyushin, Alexey ; Wagner, Boris ; Wagner, Vladimir ; Wan, Renzhuo ; Wang, Yaping ; Wang, Yifei ; Wang, Mengliang ; Wang, Dong ; Watanabe, Kengo ; Weber, Michael ; Wessels, Johannes ; Westerhoff, Uwe ; Wiechula, Jens ; Wikne, Jon ; Rudolf Wilde, Martin ; Andrzej Wilk, Grzegorz ; Wilk, Alexander ; Williams, M. Crispin S. ; Windelband, Bernd ; Xaplanteris Karampatsos, Leonidas ; Yaldo, Chris G. ; Yamaguchi, Yorito ; Yang, Hongyan ; Yang, Shiming ; Yasnopolsky, Stanislav ; Yi, JunGyu ; Yin, Zhongbao ; Yoo, In-Kwon ; Yoon, Jongik ; Yu, Weilin ; Yuan, Xianbao ; Yushmanov, Igor ; Zaccolo, Valentina ; Zach, Cenek ; Zampolli, Chiara ; Zaporozhets, Sergey ; Zarochentsev, Andrey ; Závada, Petr ; Zaviyalov, Nikolai ; Zbroszczyk, Hanna Paulina ; Zelnicek, Pierre ; Ion Zgura, Sorin ; Zhalov, Mikhail ; Zhang, Haitao ; Zhang, Xiaoming ; Zhou, Fengchu ; Zhou, You ; Zhou, Daicui ; Zhu, Hongsheng ; Zhu, Jianhui ; Zhu, Jianlin ; Zhu, Xiangrong ; Zichichi, Antonino ; Zimmermann, Alice ; Zinovjev, Gennady M. ; Denis Zoccarato, Yannick ; Zynovyev, Mykhaylo ; Zyzak, Maksym
Angular correlations between charged trigger and associated particles are measured by the ALICE detector in p–Pb collisions at a nucleon–nucleon centre-of-mass energy of 5.02 TeV for transverse momentum ranges within 0.5<pT,assoc<pT,trig<4 GeV/c. The correlations are measured over two units of pseudorapidity and full azimuthal angle in different intervals of event multiplicity, and expressed as associated yield per trigger particle. Two long-range ridge-like structures, one on the near side and one on the away side, are observed when the per-trigger yield obtained in low-multiplicity events is subtracted from the one in high-multiplicity events. The excess on the near-side is qualitatively similar to that recently reported by the CMS Collaboration, while the excess on the away-side is reported for the first time. The two-ridge structure projected onto azimuthal angle is quantified with the second and third Fourier coefficients as well as by near-side and away-side yields and widths. The yields on the near side and on the away side are equal within the uncertainties for all studied event multiplicity and pT bins, and the widths show no significant evolution with event multiplicity or pT. These findings suggest that the near-side ridge is accompanied by an essentially identical away-side ridge.
Pirkis, Jane ; Gunnell, David ; Shin, Sangsoo ; Del Pozo-Banos, Marcos ; Arya, Vikas ; Analuisa Aguilar, Pablo ; Appleby, Louis ; Yasir Arafat, S. M. ; Arensman, Ella ; Ayuso-Mateos, Jose Luis ; Pal Singh Balhara, Yatan ; Bantjes, Jason ; Baran, Anna ; Behera, Chittaranjan ; Bertolote, Jose ; Borges, Guilherme ; Bray, Michael ; Brečić, Petrana ; Caine, Eric ; Calati, Raffaella ; Carli, Vladimir ; Castelpietra, Giulio ; Fong Chan, Lai ; Chang, Shu-Sen ; Colchester, David ; Coss-Guzmán, Maria ; Crompton, David ; Ćurković, Marko ; Dandona, Rakhi ; De Jaegere, Eva ; De Leo, Diego ; Deisenhammer, Eberhard A. ; Dwyer, Jeremy ; Erlangsen, Annette ; Faust, Jeremy S. ; Fornaro, Michele ; Fortune, Sarah ; Garrett, Andrew ; Gentile, Guendalina ; Gerstner, Rebekka ; Gilissen, Renske ; Gould, Madelyn ; Kumar Gupta, Sudhir ; Hawton, Keith ; Holz, Franziska ; Kamenshchikov, Iurii ; Kapur, Navneet ; Kasal, Alexandr ; Khan, Murad ; Kirtley, Olivia J. ; Knipe, Duleeka ; Kõlves, Kairi ; Kölzer, Sarah C. ; Krivda, Hryhorii ; Leske, Stuart ; Madeddu, Fabio ; Marshall, Andrew ; Memon, Anjum ; Mittendorfer-Rutz, Ellenor ; Nestadt, Paul ; Neznanov, Nikolay ; Niederkrotenthaler, Thomas ; Nielsen, Emma ; Nordentoft, Merete ; Oberlerchner, Herwig ; O’Connor, Rory C. ; Papsdorf, Rainer ; Partonen, Timo ; Phillips, Michael R. ; Platt, Steve ; Portzky, Gwendolyn ; Psota, Georg ; Qin, Ping ; Radeloff, Daniel ; Reif, Andreas ; Reif-Leonhard, Christine ; Rezaeian, Mohsen ; Román-Vázquez, Nayda ; Roskar, Saska ; Rozanov, Vsevolod ; Sara, Grant ; Scavacini, Karen ; Schneider, Barbara ; Semenova, Natalia ; Sinyor, Mark ; Tambuzzi, Stefano ; Townsend, Ellen ; Ueda, Michiko ; Wasserman, Danuta ; Webb, Roger T. ; Winkler, Petr ; Yip, Paul S. F. ; Zalsman, Gil ; Zoja, Riccardo ; John, Ann ; Spittal, Matthew J.
Background: Predicted increases in suicide were not generally observed in the early months of the COVID-19 pandemic. However, the picture may be changing and patterns might vary across demographic groups. We aimed to provide a timely, granular picture of the pandemic's impact on suicides globally.
Methods: We identified suicide data from official public-sector sources for countries/areas-within-countries, searching websites and academic literature and contacting data custodians and authors as necessary. We sent our first data request on 22nd June 2021 and stopped collecting data on 31st October 2021. We used interrupted time series (ITS) analyses to model the association between the pandemic's emergence and total suicides and suicides by sex-, age- and sex-by-age in each country/area-within-country. We compared the observed and expected numbers of suicides in the pandemic's first nine and first 10-15 months and used meta-regression to explore sources of variation.
Findings: We sourced data from 33 countries (24 high-income, six upper-middle-income, three lower-middle-income; 25 with whole-country data, 12 with data for area(s)-within-the-country, four with both). There was no evidence of greater-than-expected numbers of suicides in the majority of countries/areas-within-countries in any analysis; more commonly, there was evidence of lower-than-expected numbers. Certain sex, age and sex-by-age groups stood out as potentially concerning, but these were not consistent across countries/areas-within-countries. In the meta-regression, different patterns were not explained by countries’ COVID-19 mortality rate, stringency of public health response, economic support level, or presence of a national suicide prevention strategy. Nor were they explained by countries’ income level, although the meta-regression only included data from high-income and upper-middle-income countries, and there were suggestions from the ITS analyses that lower-middle-income countries fared less well.
Interpretation: Although there are some countries/areas-within-countries where overall suicide numbers and numbers for certain sex- and age-based groups are greater-than-expected, these countries/areas-within-countries are in the minority. Any upward movement in suicide numbers in any place or group is concerning, and we need to remain alert to and respond to changes as the pandemic and its mental health and economic consequences continue.
Hudson, Lawrence N. ; Newbold, Tim ; Contu, Sara ; Hill, Samantha L. L. ; Lysenko, Igor ; Palma, Adriana de ; Phillips, Helen R. P. ; Senior, Rebecca A. ; Bennett, Dominic J. ; Booth, Hollie ; Choimes, Argyrios ; Correia, David L. P. ; Day, Julie ; Echeverria-Londono, Susy ; Garon, Morgan ; Harrison, Michelle L. K. ; Ingram, Daniel J. ; Jung, Martin ; Kemp, Victoria ; Kirkpatrick, Lucinda ; Martin, Callum D. ; Pan, Yuan ; White, Hannah J. ; Aben, Job ; Abrahamczyk, Stefan ; Adum, Gilbert B. ; Aguilar-Barquero, Virginia ; Aizen, Marcelo ; Ancrenaz, Marc ; Arbelaez-Cortes, Enrique ; Armbrecht, Inge ; Azhar, Badrul ; Azpiroz, Adrián B. ; Baeten, Lander ; Báldi, András ; Banks, John E. ; Barlow, Jos ; Batáry, Péter ; Bates, Adam J. ; Bayne, Erin M. ; Beja, Pedro ; Berg, Åke ; Berry, Nicholas J. ; Bicknell, Jake E. ; Bihn, Jochen H. ; Böhning-Gaese, Katrin ; Boekhout, Teun ; Boutin, Celine ; Bouyer, Jeremy ; Brearley, Francis Q. ; Brito, Isabel ; Brunet, Jörg ; Buczkowski, Grzegorz ; Buscardo, Erika ; Cabra-Garcia, Jimmy ; Calvino-Cancela, Maria ; Cameron, Sydney A. ; Cancello, Eliana M. ; Carrijo, Tiago F. ; Carvalho, Anelena L. ; Castro, Helena ; Castro-Luna, Alejandro Antonio ; Cerda, Rolando ; Cerezo, Alexis ; Chauvat, Matthieu ; Clarke, Frank M. ; Cleary, Daniel F. R. ; Connop, Stuart P. ; D'Aniello, Biagio ; Silva, Pedro Giovani da ; Darvill, Ben ; Dauber, Jens ; Dejean, Alain ; Diekötter, Tim ; Dominguez-Haydar, Yamileth ; Dormann, Carsten F. ; Dumont, Bertrand ; Dures, Simon G. ; Dynesius, Mats ; Edenius, Lars ; Elek, Zoltan ; Entling, Martin H. ; Farwig, Nina ; Fayle, Tom M. ; Felicioli, Antonio ; Felton, Annika M. ; Ficetola, Gentile Francesco ; Filgueiras, Bruno K. C. ; Fonte, Steve J. ; Fraser, Lauchlan H. ; Fukuda, Daisuke ; Furlani, Dario ; Ganzhorn, Jörg U. ; Garden, Jenni G. ; Gheler-Costa, Carla ; Giordani, Paolo ; Giordano, Simonetta ; Gottschalk, Marco S. ; Goulson, Dave ; Gove, Aaron D. ; Grogan, James ; Hanley, Mick E. ; Hanson, Thor ; Hashim, Nor R. ; Hawes, Joseph E. ; Hébert, Christian ; Helden, Alvin J. ; Henden, John-André ; Hernández, Lionel ; Herzog, Felix ; Higuera-Diaz, Diego ; Hilje, Branko ; Horgan, Finbarr G. ; Horvath, Roland ; Hylander, Kristoffer ; Horvath, Roland ; Isaacs-Cubides, Paola ; Ishitani, Mashiro ; Jacobs, Carmen T. ; Jaramillo, Victor J. ; Jauker, Birgit ; Jonsell, Matts ; Jung, Thomas S. ; Kapoor, Vena ; Kati, Vassiliki ; Katovai, Eric ; Kessler, Michael ; Knop, Eva ; Kolb, Annette ; Körösi, Àdám ; Lachat, Thibault ; Lantschner, Victoria ; Le Féon, Violette ; LeBuhn, Gretchen ; Légaré, Jean-Philippe ; Letcher, Susan G. ; Littlewood, Nick A. ; López-Quintero, Carlos A. ; Louhaichi, Mounir ; Lövei, Gabor L. ; Lucas-Borja, Manuel Esteban ; Luja, Victor H. ; Maeto, Kaoru ; Magura, Tibor ; Mallari, Neil Aldrin D. ; Marin-Spiotta, Erika ; Marshall, Edward Jon P. ; Martínez, Eliana ; Mayfield, Margaret M. ; Mikusinski, Gregorz ; Milder, Jeffery C. ; Miller, James R. ; Morales, Carolina L. ; Muriithi-Muchane, Mary Nyawira ; Muchane, Muchai ; Naidoo, Robin ; Nakamura, Akihiro ; Naoe, Shoji ; Nates-Parra, Guiomar ; Navarerete Gutierrez, Dario A. ; Neuschulz, Eike Lena ; Noreika, Norbertas ; Norfolk, Olivia ; Noriega, Jorge Ari ; Nöske, Nicole M. ; O'Dea, Niall ; Oduro, William ; Ofori-Boateng, Caleb ; Oke, Chris O. ; Osgathorpe, Lynne M. ; Paritsis, Juan ; Parrah, Alejandro ; Pelegrin, Nicolás ; Peres, Carlos A. ; Persson, Anna S. ; Petanidou, Theodora ; Phalan, Ben ; Philips, T. Keith ; Poveda, Katja ; Power, Eileen F. ; Presley, Steven J. ; Proença, Vânia ; Quaranta, Marino ; Quintero, Carolina ; Redpath-Downing, Nicola A. ; Reid, J. Leighton ; Reis, Yana T. ; Ribeiro, Danilo B. ; Richardson, Barbara A. ; Richardson, Michael J. ; Robles, Carolina A. ; Römbke, Jörg ; Romero-Duque, Luz Piedad ; Rosselli, Loreta ; Rossiter, Stephen J. ; Roulston, T'ai H. ; Rousseau, Laurent ; Sadler, Jonathan P. ; Sáfián, Szbolcs ; Saldaña-Vásquez, Romeo A. ; Samnegård, Ulrika ; Schüepp, Christof ; Schweiger, Oliver ; Sedlock, Jodi L. ; Shahabuddin, Ghazala ; Sheil, Douglas ; Silva, Fernando A. B. ; Slade, Eleanor ; Smith-Pardo, Allan H. ; Sodhi, Navjot S. ; Somarriba, Eduardo J. ; Sosa, Ramón A. ; Stout, Jane C. ; Struebig, Matthew J. ; Sung, Yik-Hei ; Threlfall, Caragh G. ; Tonietto, Rebecca ; Tóthmérész, Béla ; Tscharntke, Teja ; Turner, Edgar C. ; Tylianakis, Jason M. ; Vanbergen, Adam J. ; Vassilev, Kiril ; Verboven, Hans A. F. ; Vergara, Carlos H. ; Vergara, Pablo M. ; Verhulst, Jort ; Walker, Tony R. ; Wang, Yanping ; Watling, James I. ; Wells, Konstans ; Williams, Christopher D. ; Willig, Michael R. ; Woinarski, John Casimir Zichy ; Wolf, Jan H. D. ; Woodcock, Ben A. ; Yu, Douglas W. ; Zailsev, Andreys ; Collen, Ben ; Ewers, Rob M. ; Mace, Georgina M. ; Purves, Drew W. ; Scharlemann, Jörn P. W. ; Pervis, Andy
Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species’ threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that support computation of a range of biodiversity indicators, is necessary to enable better understanding of historical declines and to project – and avert – future declines. We describe and assess a new database of more than 1.6 million samples from 78 countries representing over 28,000 species, collated from existing spatial comparisons of local-scale biodiversity exposed to different intensities and types of anthropogenic pressures, from terrestrial sites around the world. The database contains measurements taken in 208 (of 814) ecoregions, 13 (of 14) biomes, 25 (of 35) biodiversity hotspots and 16 (of 17) megadiverse countries. The database contains more than 1% of the total number of all species described, and more than 1% of the described species within many taxonomic groups – including flowering plants, gymnosperms, birds, mammals, reptiles, amphibians, beetles, lepidopterans and hymenopterans. The dataset, which is still being added to, is therefore already considerably larger and more representative than those used by previous quantitative models of biodiversity trends and responses. The database is being assembled as part of the PREDICTS project (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems – www.predicts.org.uk). We make site-level summary data available alongside this article. The full database will be publicly available in 2015.
Casey, Jillian P. ; Magalhães, Tiago R. ; Conroy, Judith M. ; Regan, Regina ; Shah, Naisha ; Anney, Richard ; Shields, Denis C. ; Abrahams, Brett S. ; Almeida, Joana ; Bacchelli, Elena ; Bailey, Anthony J. ; Baird, Gillian ; Battaglia, Agatino ; Berney, Tom ; Bolshakova, Nadia ; Bolton, Patrick F. ; Bourgeron, Thomas ; Brennan, Sean ; Cali, Phil ; Correia, Catarina ; Corsello, Christina ; Coutanche, Marc ; Dawson, Geraldine ; Jonge, Maretha de ; Delorme, Richard ; Duketis, Eftichia ; Duque, Frederico ; Estes, Annette ; Farrar, Penny ; Fernandez, Bridget A. ; Folstein, Susan E. ; Foley, Suzanne ; Fombonne, Eric ; Freitag, Christine M. ; Gilbert, John ; Gillberg, Christopher ; Glessner, Joseph T. ; Green, Jonathan ; Guter, Stephen J. ; Hakonarson, Hakon ; Holt, Richard ; Hughes, Gillian ; Hus, Vanessa ; Igliozzi, Roberta ; Kim, Cecilia ; Klauck, Sabine M. ; Kolevzon, Alexander ; Lamb, Janine A. ; Leboyer, Marion ; Le Couteur, Ann ; Leventhal, Bennett L. ; Lord, Catherine ; Lund, Sabata C. ; Maestrini, Elena ; Mantoulan, Carine ; Marshall, Christian R. ; McConachie, Helen ; McDougle, Christopher J. ; McGrath, Jane ; McMahon, William M. ; Merikangas, Alison ; Miller, Judith ; Minopoli, Fiorella ; Mirza, Ghazala K. ; Munson, Jeff ; Nelson, Stanley F. ; Nygren, Gudrun ; Oliveira, Guiomar ; Pagnamenta, Alistair T. ; Papanikolaou, Katerina ; Parr, Jeremy R. ; Parrini, Barbara ; Pickles, Andrew ; Pinto, Dalila ; Piven, Joseph ; Posey, David J. ; Poustka, Annemarie ; Poustka, Fritz ; Ragoussis, Jiannis ; Roge, Bernadette ; Rutter, Michael L. ; Sequeira, Ana F. ; Soorya, Latha ; Sousa, Inês ; Sykes, Nuala ; Stoppioni, Vera ; Tancredi, Raffaella ; Tauber, Maïté ; Thompson, Ann P. ; Thomson, Susanne ; Tsiantis, John ; Engeland, Herman van ; Vincent, John B. ; Volkmar, Fred ; Vorstman, Jacob A. S. ; Wallace, Simon ; Wang, Kai ; Wassink, Thomas H. ; White, Kathy ; Wing, Kirsty ; Wittemeyer, Kerstin ; Yaspan, Brian L. ; Zwaigenbaum, Lonnie ; Betancur, Catalina ; Buxbaum, Joseph D. ; Cantor, Rita M. ; Cook, Edwin H. ; Coon, Hilary ; Cuccaro, Michael L. ; Geschwind, Daniel H. ; Haines, Jonathan L. ; Hallmayer, Joachim ; Monaco, Anthony P. ; Nurnberger, John I. ; Pericak-Vance, Margaret Ann ; Schellenberg, Gerard D. ; Scherer, Stephen W. ; Sutcliffe, James S. ; Szatmari, Peter ; Vieland, Veronica J. ; Wijsman, Ellen M. ; Green, Andrew ; Gill, Michael ; Gallagher, Louise ; Vicente, Astrid M. ; Ennis, Sean
Autism spectrum disorder (ASD) is a highly heritable disorder of complex and heterogeneous aetiology. It is primarily characterized by altered cognitive ability including impaired language and communication skills and fundamental deficits in social reciprocity. Despite some notable successes in neuropsychiatric genetics, overall, the high heritability of ASD (~90%) remains poorly explained by common genetic risk variants. However, recent studies suggest that rare genomic variation, in particular copy number variation, may account for a significant proportion of the genetic basis of ASD. We present a large scale analysis to identify candidate genes which may contain low-frequency recessive variation contributing to ASD while taking into account the potential contribution of population differences to the genetic heterogeneity of ASD. Our strategy, homozygous haplotype (HH) mapping, aims to detect homozygous segments of identical haplotype structure that are shared at a higher frequency amongst ASD patients compared to parental controls. The analysis was performed on 1,402 Autism Genome Project trios genotyped for 1 million single nucleotide polymorphisms (SNPs). We identified 25 known and 1,218 novel ASD candidate genes in the discovery analysis including CADM2, ABHD14A, CHRFAM7A, GRIK2, GRM3, EPHA3, FGF10, KCND2, PDZK1, IMMP2L and FOXP2. Furthermore, 10 of the previously reported ASD genes and 300 of the novel candidates identified in the discovery analysis were replicated in an independent sample of 1,182 trios. Our results demonstrate that regions of HH are significantly enriched for previously reported ASD candidate genes and the observed association is independent of gene size (odds ratio 2.10). Our findings highlight the applicability of HH mapping in complex disorders such as ASD and offer an alternative approach to the analysis of genome-wide association data.
Anney, Richard ; Klei, Lambertus ; Pinto, Dalila ; Regan, Regina ; Conroy, Judith ; Magalhães, Tiago R. ; Correia, Catarina ; Abrahams, Brett S. ; Sykes, Nuala ; Pagnamenta, Alistair T. ; Almeida, Joana ; Bacchelli, Elena ; Bailey, Anthony J. ; Baird, Gillian ; Battaglia, Agatino ; Berney, Tom ; Bolshakova, Nadia ; Bölte, Sven ; Bolton, Patrick F. ; Bourgeron, Thomas ; Brennan, Sean ; Brian, Jessica ; Carson, Andrew R. ; Casallo, Guillermo ; Casey, Jillian ; Chu, Su H. ; Cochrane, Lynne ; Corsello, Christina ; Crawford, Emily L. ; Crossett, Andrew ; Dawson, Geraldine ; Jonge, Maretha de ; Delorme, Richard ; Drmic, Irene ; Duketis, Eftichia ; Duque, Frederico ; Estes, Annette ; Farrar, Penny ; Fernandez, Bridget A. ; Folstein, Susan E. ; Fombonne, Eric ; Freitag, Christine M. ; Gilbert, John ; Gillberg, Christopher ; Glessner, Joseph T. ; Goldberg, Jeremy ; Green, Jonathan ; Guter, Stephen J. ; Hakonarson, Hakon ; Heron, Elizabeth A. ; Hill, Matthew ; Holt, Richard ; Howe, Jennifer L. ; Hughes, Gillian ; Hus, Vanessa ; Igliozzi, Roberta ; Kim, Cecilia ; Klauck, Sabine M. ; Kolevzon, Alexander ; Korvatska, Olena ; Kustanovich, Vlad ; Lajonchere, Clara M. ; Lamb, Janine A. ; Laskawiec, Magdalena ; Leboyer, Marion ; Le Couteur, Ann ; Leventhal, Bennett L. ; Lionel, Anath C. ; Liu, Xiao-Qing ; Lord, Catherine ; Lotspeich, Linda ; Lund, Sabata C. ; Maestrini, Elena ; Mahoney, William ; Mantoulan, Carine ; Marshall, Christian R. ; McConachie, Helen ; McDougle, Christopher J. ; McGrath, Jane ; McMahon, William M. ; Melhem, Nadine M. ; Merikangas, Alison ; Migita, Ohsuke ; Minshew, Nancy J. ; Mirza, Ghazala K. ; Munson, Jeff ; Nelson, Stanley F. ; Noakes, Carolyn ; Noor, Abdul ; Nygren, Gudrun ; Oliveira, Guiomar ; Papanikolaou, Katerina ; Parr, Jeremy R. ; Parrini, Barbara ; Paton, Tara ; Pickles, Andrew ; Piven, Joseph ; Posey, David J. ; Poustka, Annemarie ; Poustka, Fritz ; Prasad, Aparna ; Ragoussis, Jiannis ; Renshaw, Katy ; Rickaby, Jessica ; Roberts, Wendy ; Roeder, Kathryn ; Roge, Bernadette ; Rutter, Michael L. ; Bierut, Laura Jean ; Rice, John P. ; Salt, Jeff ; Sansom, Katherine ; Sato, Daisuke ; Segurado, Ricardo ; Senman, Lili ; Shah, Naisha ; Sheffield, Val C. ; Soorya, Latha ; Sousa, Inês ; Stoppioni, Vera ; Strawbridge, Christina ; Tancredi, Raffaella ; Tansey, Katherine ; Thiruvahindrapduram, Bhooma ; Thompson, Ann P. ; Thomson, Susanne ; Tryfon, Ana ; Tsiantis, John ; Engeland, Herman van ; Vincent, John B. ; Volkmar, Fred ; Wallace, Simon ; Wang, Kai ; Wang, Zhouzhi ; Wassink, Thomas H. ; Wing, Kirsty ; Wittemeyer, Kerstin ; Wood, Shawn ; Yaspan, Brian L. ; Zurawiecki, Danielle ; Zwaigenbaum, Lonnie ; Betancur, Catalina ; Buxbaum, Joseph D. ; Cantor, Rita M. ; Cook, Edwin H. ; Coon, Hilary ; Cuccaro, Michael L. ; Gallagher, Louise ; Geschwind, Daniel H. ; Gill, Michael ; Haines, Jonathan L. ; Miller, Judith ; Monaco, Anthony P. ; Nurnberger, John I. ; Paterson, Andrew D. ; Pericak-Vance, Margaret Ann ; Schellenberg, Gerard D. ; Scherer, Stephen W. ; Sutcliffe, James S. ; Szatmari, Peter ; Vicente, Astrid M. ; Vieland, Veronica J. ; Wijsman, Ellen M. ; Devlin, Bernie ; Ennis, Sean ; Hallmayer, Joachim
Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the Autism Genome Project (AGP) Consortium genotyped 1558 rigorously defined ASD families for 1 million single-nucleotide polymorphisms (SNPs) and analyzed these SNP genotypes for association with ASD. In one of four primary association analyses, the association signal for marker rs4141463, located within MACROD2, crossed the genome-wide association significance threshold of P < 5 × 10−8. When a smaller replication sample was analyzed, the risk allele at rs4141463 was again over-transmitted; yet, consistent with the winner's curse, its effect size in the replication sample was much smaller; and, for the combined samples, the association signal barely fell below the P < 5 × 10−8 threshold. Exploratory analyses of phenotypic subtypes yielded no significant associations after correction for multiple testing. They did, however, yield strong signals within several genes, KIAA0564, PLD5, POU6F2, ST8SIA2 and TAF1C.
Neurogenic/neuropathic bowel dysfunction (NBD) is common in children who are affected by congenital and acquired neurological disease, and negatively impacts quality of life. In the past, NBD received less attention than neurogenic bladder, generally being considered only in spina bifida (the most common cause of pediatric NBD). Many methods of conservative and medical management of NBD are reported, including relatively recently Transanal Irrigation (TAI). Based on the literature and personal experience, an expert group (pediatric urologists/surgeons/gastroenterologists with specific experience in NBD) focused on NBD in children and adolescents. A statement document was created using a modified Delphi method. The range of causes of pediatric NBD are discussed in this paper. The various therapeutic approaches are presented to improve clinical management. The population of children and adolescents with NBD is increasing, due both to the higher survival rate and better diagnosis. While NBD is relatively predictable in producing either constipation or fecal incontinence, or both, its various effects on each patient will depend on a wide range of underlying causes and accompanying comorbidities. For this reason, management of NBD should be tailored individually with a combined multidisciplinary therapy appropriate for the status of the affected child and caregivers.
Bruijn, Clara M. A. de ; Safder, Shaista ; Rolle, Udo ; Mosiello, Giovanni ; Marshall, David ; Christiansen, Albert B. ; Benninga, Marc A.
Objective: To develop a reliable and valid scoring tool, the Pediatric Bowel Management Scoring Tool (PBMST), to better guide management of constipation in pediatric patients.
Study design: The project comprised 2 stages, development of the questionnaire and construction of the bowel management score. Two questionnaires were created, one for children aged 8-18 years to self-report and one parent proxy-report for children aged 4-8 years. Questions regarding physical symptoms (n = 6), emotional aspects (n = 2), social activities/school (n = 1), and treatment (n = 1) were included. Patients (or parents of patients) with symptoms of constipation completed the questionnaire. The reproducibility of each question was computed using the Cohen weighted kappa coefficient (κ). A bowel management score was developed using logistic regression analysis, assessing the associations between the questions and impact on self-reported quality of life (QoL). Questions with adequate reproducibility and significantly associated with QoL were incorporated into the score.
Results: The questionnaire was completed by 385 patients. Six questions met the inclusion criteria and were incorporated into the score: stool shape (range, 0-3 points), anorectal pain (0-4 points), abdominal pain (0-3 points), frequency of fecal incontinence (0-3 points), assistance of caregivers (0-3 points), and interference with social activities (0-6 points). Differences in bowel management scores among patients reporting no, little, some, or major impact on QoL were statistically significant (P < .001).
Conclusions: The newly developed and validated PBMST is a reliable tool for evaluating bowel management strategies in children with constipation.
Slik, J. W. Ferry ; Franklin, Janet ; Arroyo-Rodríguez, Víctor ; Field, Richard ; Aguilar, Salomon ; Aguirre, Nikolay ; Ahumada, Jorge ; Aiba, Shin-Ichiro ; Alves, Luciana F. ; Anitha, Kamalakumari ; Avella, Andres ; Mora, Francisco ; Aymard, Gerardo A. ; Báez, Selene ; Balvanera, Patricia ; Bastian, Meredith L. ; Bastin, Jean-François ; Bellingham, Peter ; van den Berg, Eduardo ; da Conceição Bispo, Polyanna ; Boeckx, Pascal ; Böhning-Gaese, Katrin ; Bongers, Frans ; Boyle, Brad ; Brambach, Fabian ; Brearley, Francis Q. ; Brown, Sandra ; Chai, Shauna-Lee ; Chazdon, Robin L. ; Chen, Shengbin ; Chhang, Phourin ; Chuyong, George ; Ewangog, Corneille ; Coronado, Indiana ; Cristóbal-Azkarate, Jurgi ; Culmsee, Heike ; Damas, Kipiro ; Dattaraja, Handanakere Shivaramaiah ; Davidar, Priya ; DeWalt, Saara J. ; Din, Hazimah ; Drake, Donald R. ; Duque, Alvaro ; Durigan, Giselda ; Eichhorn, Karl ; Schmidt Eler, Eduardo ; Enoki, Tsutomu ; Ensslin, Andreas ; Fandohan, Adandé Belarmain ; Farwig, Nina ; Feeley, Kenneth J. ; Fischer, Markus ; Forshed, Olle ; Garcia, Queila Souza ; Garkoti, Satish Chandra ; Gillespie, Thomas William ; Gillet, Jean-Francois ; Gonmadje, Christelle ; Granzow-de la Cerda, Iñigo ; Griffith, Daniel M. ; Grogan, James ; Hakeem, Khalid Rehman ; Harris, David J. ; Harrison, Rhett D. ; Hector, Andy ; Hemp, Andreas ; Homeier, Jürgen ; Hussain, M. Shah ; Ibarra Manríquez, Guillermo ; Hanum, I. Faridah ; Imai, Nobuo ; Jansen, Patrick A. ; Joly, Carlos Alfredo ; Joseph, Shijo ; Kartawinata, Kuswata ; Kearsley, Elizabeth ; Kelly, Daniel L. ; Kessler, Michael ; Killeen, Timothy J. ; Kooyman, Robert ; Laumonier, Yves ; Laurance, Susan G. ; Laurance, William F. ; Lawes, Michael J. ; Letcher, Susan G. ; Lindsell, Jeremy ; Lovett, Jon ; Lozada, Jose ; Lu, Xinghui ; Lykke, Anne Mette ; Bin Mahmud, Khairil ; Mahayani, Ni Putu Diana ; Mansor, Asyraf ; Marshall, Andrew R. ; Martin, Emanuel H. ; Leal Matos, Darley Calderado ; Meave, Jorge A. ; Melo, Felipe P. L. ; Aguirre Mendoza, Zhofre ; Metali, Faizah ; Medjibe, Vincent P. ; Metzger, Jean Paul ; Metzker, Thiago ; Mohandass, Dharmalingam ; Munguía-Rosas, Miguel A. ; Muñoz, Rodrigo ; Nurtjahy, Eddy ; Lenza de Oliveira, Eddie ; Onrizal, Onrizal ; Parolin, Pia ; Parren, Marc ; Parthasarathy, Narayanaswamy ; Paudel, Ekananda ; Perez, Rolando ; Pérez-García, Eduardo A. ; Pommer, Ulf ; Poorter, Lourens ; Qi, Lan ; F. Piedade, Maria Teresa ; Rodrigues Pinto, José Roberto ; Dalberg Poulsen, Axel ; Poulsen, John R. ; Powers, Jennifer S. ; Prasad, Rama Chandra ; Puyravaud, Jean-Philippe ; Rangel, Orlando ; Reitsma, Jan ; S. B. Rocha, Diogo ; Rolim, Samir ; Rovero, Francesco ; Rozak, Andes ; Ruokolainen, Kalle ; Rutishauser, Ervan ; Rutten, Gemma ; Mohd. Said, Mohd. Nizam ; Saiter, Felipe Z. ; Saner, Philippe ; Santos, Braulio ; dos Santos, João Roberto ; Sarker, Swapan Kumar ; Schmitt, Christine B. ; Schöngart, Jochen ; Schulze, Mark ; Sheil, Douglas ; Sist, Plinio ; Souza, Alexandre F. ; Spironello, Wilson Roberto ; Sposito, Tereza ; Steinmetz, Robert ; Stevart, Tariq ; Suganuma, Marcio Seiji ; Sukri, Rahayu ; Sultana, Aisha ; Sukumar, Raman ; Sunderland, Terry ; Supriyadi, Agus ; Suresh, Hebbalalu S. ; Suzuki, Eizi ; Tabarelli, Marcelo ; Tang, Jianwei ; Tanner, Edmund V. J. ; Targhetta, Natalia ; Theilade, Ida ; Thomas, Duncan ; Timberlake, Jonathan ; de Morisson Valeriano, Márcio ; Valkenburg, Johan van ; Do, Tran Van ; Sam, Hoang Van ; Vandermeer, John H. ; Verbeeck, Hans ; Vetaas, Ole Reidar ; Adekunle, Victor ; Vieira, Simone A. ; Webb, Campbell O. ; Webb, Edward L. ; Whitfeld, Timothy ; Wich, Serge ; Williams, John ; Wiser, Susan ; Wittmann, Florian ; Yang, Xiaobo ; Adou Yao, C. Yves ; Yap, Sandra L. ; Zahawie, Rakan A. ; Zakaria, Rahmad ; Zang, Runguo
Knowledge about the biogeographic affinities of the world’s tropical forests helps to better understand regional differences in forest structure, diversity, composition, and dynamics. Such understanding will enable anticipation of region-specific responses to global environmental change. Modern phylogenies, in combination with broad coverage of species inventory data, now allow for global biogeographic analyses that take species evolutionary distance into account. Here we present a classification of the world’s tropical forests based on their phylogenetic similarity. We identify five principal floristic regions and their floristic relationships: (i) Indo-Pacific, (ii) Subtropical, (iii) African, (iv) American, and (v) Dry forests. Our results do not support the traditional neo- versus paleotropical forest division but instead separate the combined American and African forests from their Indo-Pacific counterparts. We also find indications for the existence of a global dry forest region, with representatives in America, Africa, Madagascar, and India. Additionally, a northern-hemisphere Subtropical forest region was identified with representatives in Asia and America, providing support for a link between Asian and American northern-hemisphere forests.
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