Cotranscriptional folding and fragment-based drug discovery of regulatory mRNA
- This work investigated cyclic-di-nucleotide (CDN) riboswitches, gaining a detailed understanding of their folding during transcription and the feasibility of 19F-NMR fragment-based screening for RNA binding lead structures for riboswitch aptamers.
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| Author: | Albrecht Eduard VölkleinORCiDGND |
|---|---|
| URN: | urn:nbn:de:hebis:30:3-831749 |
| DOI: | https://doi.org/10.21248/gups.83174 |
| Place of publication: | Frankfurt am Main |
| Referee: | Harald SchwalbeORCiDGND, Michael GöbelORCiDGND |
| Document Type: | Doctoral Thesis |
| Language: | English |
| Date of Publication (online): | 2024/04/03 |
| Year of first Publication: | 2023 |
| Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
| Granting Institution: | Johann Wolfgang Goethe-Universität |
| Date of final exam: | 2024/03/11 |
| Release Date: | 2024/04/03 |
| Page Number: | 187 |
| HeBIS-PPN: | 516797069 |
| Institutes: | Biochemie, Chemie und Pharmazie |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| Sammlungen: | Universitätspublikationen |
| Licence (German): |  Deutsches Urheberrecht |
