Identification of developing multiple organ failure in sepsis patients with low or moderate SOFA scores
- An early identification of sepsis patients likely to progress towards multiple organ failure is crucial in order to initiate targeted therapeutic strategies to decrease mortality. Our recent publication highlighted the greater accuracy of mid-regional proadrenomedullin (MR-proADM) compared with conventional biomarkers and clinical scores in predicting 28-day mortality in patients with initially low (≤7 points; N = 240) or moderate (8–13 points; N = 653) Sepsis-related Organ Failure Assessment (SOFA) scores, thus confirming results from smaller investigations. This additional post hoc analysis aimed to further describe the non-surviving patient population of both subgroups and identify those likely to progress towards sepsis-related multiple organ failure. ...
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| Verfasserangaben: | Gunnar Elke, Frank Bloos, Darius Cameron Wilson, Patrick MeybohmORCiDGND |
|---|---|
| URN: | urn:nbn:de:hebis:30:3-466094 |
| DOI: | https://doi.org/10.1186/s13054-018-2084-z |
| ISSN: | 1466-609X |
| ISSN: | 1364-8535 |
| Pubmed-Id: | https://pubmed.ncbi.nlm.nih.gov/29871660 |
| Titel des übergeordneten Werkes (Englisch): | Critical care |
| Verlag: | BioMed Central ; Springer |
| Verlagsort: | London ; Berlin ; Heidelberg |
| Dokumentart: | Wissenschaftlicher Artikel |
| Sprache: | Englisch |
| Jahr der Fertigstellung: | 2018 |
| Datum der Erstveröffentlichung: | 05.06.2018 |
| Veröffentlichende Institution: | Universitätsbibliothek Johann Christian Senckenberg |
| Beteiligte Körperschaft: | SepNet Critical Care Trials Group |
| Datum der Freischaltung: | 14.06.2018 |
| Jahrgang: | 22 |
| Ausgabe / Heft: | 1, Art. 147 |
| Seitenzahl: | 3 |
| Erste Seite: | 1 |
| Letzte Seite: | 3 |
| Bemerkung: | Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| HeBIS-PPN: | 434238953 |
| Institute: | Medizin / Medizin |
| DDC-Klassifikation: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Sammlungen: | Universitätspublikationen |
| Lizenz (Deutsch): |  Creative Commons - Namensnennung 4.0 |
