Long term seizure freedom on perampanel in highly drug-resistant epilepsy caused by bilateral periventricular nodular heterotopia: a case report
- Highlights • NMDA-receptor subunit expression of NR2A and NR2B is downregulated in heterotopias. • Glutamatergic transmission in the hyperexcitability of nodular heterotopias is implicated. • Mechanisms in PVNH to establish etiology specific therapies are still to be defined.
Author: | Makoto KiyoseGND, Marlies WagnerORCiDGND, Annika Männer, Sarah ReitzORCiDGND, Karl Martin KleinORCiD, Adam StrzelczykORCiDGND, Sebastian BauerORCiDGND, Felix RosenowORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-775004 |
DOI: | https://doi.org/10.1016/j.ebcr.2019.01.009 |
ISSN: | 2213-3232 |
Parent Title (English): | Epilepsy & behavior case reports |
Publisher: | Elsevier |
Place of publication: | Amsterdam |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2019/02/25 |
Date of first Publication: | 2019/02/13 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2024/06/03 |
Volume: | 11 |
Page Number: | 4 |
First Page: | 99 |
Last Page: | 102 |
HeBIS-PPN: | 519157842 |
Institutes: | Medizin |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International |