Stimulus-specific plasticity in human visual gamma-band activity and functional connectivity
- Under natural conditions, the visual system often sees a given input repeatedly. This provides an opportunity to optimize processing of the repeated stimuli. Stimulus repetition has been shown to strongly modulate neuronal-gamma band synchronization, yet crucial questions remained open. Here we used magnetoencephalography in 30 human subjects and find that gamma decreases across ≈10 repetitions and then increases across further repetitions, revealing plastic changes of the activated neuronal circuits. Crucially, increases induced by one stimulus did not affect responses to other stimuli, demonstrating stimulus specificity. Changes partially persisted when the inducing stimulus was repeated after 25 minutes of intervening stimuli. They were strongest in early visual cortex and increased interareal feedforward influences. Our results suggest that early visual cortex gamma synchronization enables adaptive neuronal processing of recurring stimuli. These and previously reported changes might be due to an interaction of oscillatory dynamics with established synaptic plasticity mechanisms.
Author: | Benjamin J. StauchORCiDGND, Alina PeterORCiDGND, Heike Schuler, Pascal FriesORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-627410 |
DOI: | https://doi.org/10.7554/eLife.68240 |
ISSN: | 2050-084X |
Parent Title (English): | eLife |
Publisher: | eLife Sciences Publications |
Place of publication: | Cambridge |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2021/08/24 |
Date of first Publication: | 2021/08/24 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2022/05/18 |
Volume: | 10 |
Issue: | art. e68240 |
Page Number: | 22 |
First Page: | 1 |
Last Page: | 22 |
Note: | PF acknowledges grant support by DFG (SPP 1665 FR2557/1-1, FOR 1847 FR2557/2-1, FR2557/5-1-CORNET, FR2557/6-1-NeuroTMR, FR2557/7-1 DualStreams), EU (FP7-604102-HBP, FP7-600730-Magnetrodes), a European Young Investigator Award, NIH (1U54MH091657-WU-Minn-Consortium-HCP), and LOEWE (NeFF). |
HeBIS-PPN: | 49608156X |
Institutes: | Medizin / Medizin |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit | |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung 4.0 |