Lange nicht-codierende RNAs in der Angiogenese

  • More than 97 percent of the transcribed RNA in mammalian cells is not coding for proteins. Among these are micro RNAs (miRs), transfer RNAs (tRNA) as well as ribosomal RNAs (rRNA) but also long non-coding RNAs (lncRNAs). This RNA class is only defined by its sequence length of more than 200 nucleotides and its lack of protein coding potential. The human genome encodes for more than 18.000 lncRNAs which contribute to gene expression control. Here, we discuss the function of these lncRNAs and how they modulate the angiogenic process of vessel growth.
Metadaten
Author:Ralf BrandesGND, Matthias LeisegangORCiDGND
URN:urn:nbn:de:hebis:30:3-637982
DOI:https://doi.org/10.1007/s12268-021-1546-z
ISSN:1868-6249
Parent Title (German):Biospektrum
Publisher:Spektrum
Place of publication:Heidelberg
Document Type:Article
Language:German
Date of Publication (online):2021/03/23
Date of first Publication:2021/03/23
Publishing Institution:Universit├Ątsbibliothek Johann Christian Senckenberg
Release Date:2022/08/22
Volume:27.2021
Issue:2
Page Number:3
First Page:146
Last Page:148
Note:
Open Access funding enabled and organized by Projekt DEAL.
HeBIS-PPN:502534427
Institutes:Medizin
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universit├Ątspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0