Intra- and interobserver variability of 4D ultrasound examination of the infrarenal aorta

  • Objectives: The four-dimensional ultrasound (4D-US) enables imaging of the aortic segment and simultaneous determination of the wall expansion. The method shows a high spatial and temporal resolution, but its in vivo reliability is so far unknown for low-measure values. The present study determines the intraobserver repeatability and interobserver reproducibility of 4D-US in the atherosclerotic and non-atherosclerotic infrarenal aorta. Methods: In all, 22 patients with non-aneurysmal aorta were examined by an experienced examiner and a medical student. After registration of 4D images, both the examiners marked the aortic wall manually before the commercially implemented speckle tracking algorithm was applied. The cyclic changes of the aortic diameter and circumferential strain were determined with the help of custom-made software. The reliability of 4D-US was tested by the intraclass correlation coefficient (ICC). Results: The 4D-US measurements showed very good reliability for the maximum aortic diameter and the circumferential strain for all patients and for the non-atherosclerotic aortae (ICC >0.7), but low reliability for circumferential strain in calcified aortae (ICC = 0.29). The observer- and masking-related variances for both maximum diameter and circumferential strain were close to zero. Conclusions: Despite the low-measured values, the high spatial and temporal resolution of the 4D-US enables a reliable evaluation of cyclic diameter changes and circumferential strain in non-aneurysmal aortae independent from the observer experience but with some limitations for calcified aortae. The 4D-US opens up a new perspective with regard to noninvasive, in vivo assessment of kinematic properties of the vessel wall in the abdominal aorta.
Metadaten
Author:Wojciech Derwich, Antonia Wiedemann, Andreas Wittek, Natalie Filmann, Christopher Blase, Thomas Schmitz-RixenORCiDGND
URN:urn:nbn:de:hebis:30:3-638781
DOI:https://doi.org/10.1002/jum.15622
ISSN:1550-9613
Parent Title (English):Journal of ultrasound in medicine
Publisher:Wiley
Place of publication:Hoboken, NJ
Document Type:Article
Language:English
Date of Publication (online):2021/01/16
Date of first Publication:2021/01/16
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2022/03/16
Volume:40
Issue:11
Page Number:12
First Page:2391
Last Page:2402
Note:
This work was funded by the Adolf Messer Foundation and the Ministry of Higher Education, Research and the Arts (Hessisches Ministerium fur Wissenschaft and Kunst, Hesse, Germany), and their support is gratefully acknowledged. The authors appreciate the contribution of Prof. Eva Herrmann from the Institute of Biostatistics and Mathematical Modeling, Goethe University for the constructive suggestions and critical comments regarding the statistical evaluation of the 4D-US reliability. Open Access funding enabled and organized by ProjektDEAL.
HeBIS-PPN:494728329
Institutes:Biowissenschaften
Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
6 Technik, Medizin, angewandte Wissenschaften / 62 Ingenieurwissenschaften / 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung-Nicht kommerziell - Keine Bearbeitung 4.0