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Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment

  • To clip or coil has been matter of debates for several years and is the domain of interdisciplinary decision making. However, the microsurgical outcome has still been elusive concerning wide neck aneurysms (WNA). A retrospective single center study was performed with all patients with ruptured WNA (rWNA) and unruptured WNA (uWNA) admitted to author´s institute between 2007–2017. Microsurgical outcome was evaluated according to Raymond-Roy occlusion grade and follow-up angiography was performed to analyze the stability of neck/aneurysm remnants and retreatment poverty. Of 805 aneurysms, 139 were rWNA (17.3%) and 148 uWNA (18.4%). Complete occlusion was achieved in 102 of 139 rWNA (73.4%) and 112 of 148 uWNA (75.6%). Neck remnants were observed in 36 patients with rWNA (25.9%) and 30 patients with uWNA (20.3%), 1 (0.7%) and 6 (4.1%) patients had aneurysmal remnant, respectively. Overall complication rate was 11.5%. At follow-up (939/1504 months), all remnants were stable except for one, which was further conservatively treated with marginal retreatment rate under 1%. Even the risk of de-novo aneurysm was higher than the risk for remnant growth (2.6% vs 0% in rWNA; 8.7% vs 5.3% in uWNA) without significant difference. Microsurgical clipping is effective for complete occlusion of r/uWNA with low complication. Furthermore, the risk of remnant growth is marginal even lower than the risk of de-novo rate low retreatment rate.
Metadaten
Author:Sae-Yeon WonORCiDGND, Volker SeifertORCiD, Daniel DubinskiORCiDGND, Sepide KashefiolaslORCiDGND, Nazife DincORCiDGND, Markus BruderORCiDGND, Jürgen KonczallaORCiDGND
URN:urn:nbn:de:hebis:30:3-722216
DOI:https://doi.org/10.1038/s41598-021-84339-x
ISSN:2045-2322
Parent Title (English):Scientific reports
Publisher:Macmillan Publishers Limited, part of Springer Nature
Place of publication:[London]
Document Type:Article
Language:English
Date of Publication (online):2021/03/02
Date of first Publication:2021/03/02
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2023/03/21
Tag:Neurology; Outcomes research
Volume:11.2021
Issue:art. 4982
Article Number:4982
Page Number:11
First Page:1
Last Page:11
Note:
Open Access funding enabled and organized by Projekt DEAL.
HeBIS-PPN:508491533
Institutes:Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - CC BY - Namensnennung 4.0 International